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Items: 36


Loss of Ataxin-1 Potentiates Alzheimer's Pathogenesis by Elevating Cerebral BACE1 Transcription.

Suh J, Romano DM, Nitschke L, Herrick SP, DiMarzio BA, Dzhala V, Bae JS, Oram MK, Zheng Y, Hooli B, Mullin K, Gennarino VA, Wasco W, Schmahmann JD, Albers MW, Zoghbi HY, Tanzi RE.

Cell. 2019 Aug 22;178(5):1159-1175.e17. doi: 10.1016/j.cell.2019.07.043.


A dynamic view of the proteomic landscape during differentiation of ReNcell VM cells, an immortalized human neural progenitor line.

Song Y, Subramanian K, Berberich MJ, Rodriguez S, Latorre IJ, Luria CM, Everley R, Albers MW, Mitchison TJ, Sorger PK.

Sci Data. 2019 Feb 19;6:190016. doi: 10.1038/sdata.2019.16.


Olanzapine Improved Symptoms and Olfactory Function in an Olfactory Reference Syndrome Patient.

Albers AD, Amato I, Albers MW.

J Neuropsychiatry Clin Neurosci. Spring 2018;30(2):164-167. doi: 10.1176/appi.neuropsych.17050096. Epub 2017 Nov 14. No abstract available.


Activity-Dependent Dysfunction in Visual and Olfactory Sensory Systems in Mouse Models of Down Syndrome.

William CM, Saqran L, Stern MA, Chiang CL, Herrick SP, Rangwala A, Albers MW, Frosch MP, Hyman BT.

J Neurosci. 2017 Oct 11;37(41):9880-9888. doi: 10.1523/JNEUROSCI.1045-17.2017. Epub 2017 Sep 12.


Nasal neuron PET imaging quantifies neuron generation and degeneration.

Van de Bittner GC, Riley MM, Cao L, Ehses J, Herrick SP, Ricq EL, Wey HY, O'Neill MJ, Ahmed Z, Murray TK, Smith JE, Wang C, Schroeder FA, Albers MW, Hooker JM.

J Clin Invest. 2017 Feb 1;127(2):681-694. doi: 10.1172/JCI89162. Epub 2017 Jan 23.


Episodic memory of odors stratifies Alzheimer biomarkers in normal elderly.

Dhilla Albers A, Asafu-Adjei J, Delaney MK, Kelly KE, Gomez-Isla T, Blacker D, Johnson KA, Sperling RA, Hyman BT, Betensky RA, Hastings L, Albers MW.

Ann Neurol. 2016 Dec;80(6):846-857. doi: 10.1002/ana.24792. Epub 2016 Nov 23.


Massachusetts Alzheimer's Disease Research Center: progress and challenges.

Hyman BT, Growdon JH, Albers MW, Buckner RL, Chhatwal J, Gomez-Isla MT, Haass C, Hudry E, Jack CR Jr, Johnson KA, Khachaturian ZS, Kim DY, Martin JB, Nitsch RM, Rosen BR, Selkoe DJ, Sperling RA, St George-Hyslop P, Tanzi RE, Yap L, Young AB, Phelps CH, McCaffrey PG.

Alzheimers Dement. 2015 Oct;11(10):1241-5. doi: 10.1016/j.jalz.2015.06.1887. Epub 2015 Aug 19. No abstract available.


Odor identification and Alzheimer disease biomarkers in clinically normal elderly.

Growdon ME, Schultz AP, Dagley AS, Amariglio RE, Hedden T, Rentz DM, Johnson KA, Sperling RA, Albers MW, Marshall GA.

Neurology. 2015 May 26;84(21):2153-60. doi: 10.1212/WNL.0000000000001614. Epub 2015 May 1.


At the interface of sensory and motor dysfunctions and Alzheimer's disease.

Albers MW, Gilmore GC, Kaye J, Murphy C, Wingfield A, Bennett DA, Boxer AL, Buchman AS, Cruickshanks KJ, Devanand DP, Duffy CJ, Gall CM, Gates GA, Granholm AC, Hensch T, Holtzer R, Hyman BT, Lin FR, McKee AC, Morris JC, Petersen RC, Silbert LC, Struble RG, Trojanowski JQ, Verghese J, Wilson DA, Xu S, Zhang LI.

Alzheimers Dement. 2015 Jan;11(1):70-98. doi: 10.1016/j.jalz.2014.04.514. Epub 2014 Jul 9. Review.


Tau-amyloid interactions in the rTgTauEC model of early Alzheimer's disease suggest amyloid-induced disruption of axonal projections and exacerbated axonal pathology.

Pooler AM, Polydoro M, Wegmann SK, Pitstick R, Kay KR, Sanchez L, Carlson GA, Gomez-Isla T, Albers MW, Spires-Jones TL, Hyman BT.

J Comp Neurol. 2013 Dec 15;521(18):4236-48. doi: 10.1002/cne.23411.


Loss of the V-ATPase B1 subunit isoform expressed in non-neuronal cells of the mouse olfactory epithelium impairs olfactory function.

Păunescu TG, Rodriguez S, Benz E, McKee M, Tyszkowski R, Albers MW, Brown D.

PLoS One. 2012;7(9):e45395. doi: 10.1371/journal.pone.0045395. Epub 2012 Sep 20.


Aβ alters the connectivity of olfactory neurons in the absence of amyloid plaques in vivo.

Cao L, Schrank BR, Rodriguez S, Benz EG, Moulia TW, Rickenbacher GT, Gomez AC, Levites Y, Edwards SR, Golde TE, Hyman BT, Barnea G, Albers MW.

Nat Commun. 2012;3:1009. doi: 10.1038/ncomms2013.


Synaptic plasticity defect following visual deprivation in Alzheimer's disease model transgenic mice.

William CM, Andermann ML, Goldey GJ, Roumis DK, Reid RC, Shatz CJ, Albers MW, Frosch MP, Hyman BT.

J Neurosci. 2012 Jun 6;32(23):8004-11. doi: 10.1523/JNEUROSCI.5369-11.2012.


The precision of axon targeting of mouse olfactory sensory neurons requires the BACE1 protease.

Cao L, Rickenbacher GT, Rodriguez S, Moulia TW, Albers MW.

Sci Rep. 2012;2:231. doi: 10.1038/srep00231. Epub 2012 Jan 20.


Mice with a "monoclonal nose": perturbations in an olfactory map impair odor discrimination.

Fleischmann A, Shykind BM, Sosulski DL, Franks KM, Glinka ME, Mei DF, Sun Y, Kirkland J, Mendelsohn M, Albers MW, Axel R.

Neuron. 2008 Dec 26;60(6):1068-81. doi: 10.1016/j.neuron.2008.10.046.


A tale of two etiologies: loss and recovery of olfactory function.

Albers MW, Marder KS.

Ann Neurol. 2008 Feb;63(2):132-4. doi: 10.1002/ana.21330. No abstract available.


Validation and optimization of statistical approaches for modeling odorant-induced fMRI signal changes in olfactory-related brain areas.

Tabert MH, Steffener J, Albers MW, Kern DW, Michael M, Tang H, Brown TR, Devanand DP.

Neuroimage. 2007 Feb 15;34(4):1375-90. Epub 2006 Dec 28.


Olfactory dysfunction as a predictor of neurodegenerative disease.

Albers MW, Tabert MH, Devanand DP.

Curr Neurol Neurosci Rep. 2006 Sep;6(5):379-86. Review.


A 10-item smell identification scale related to risk for Alzheimer's disease.

Tabert MH, Liu X, Doty RL, Serby M, Zamora D, Pelton GH, Marder K, Albers MW, Stern Y, Devanand DP.

Ann Neurol. 2005 Jul;58(1):155-60.


HIV encephalitis simulating Huntington's disease.

Sevigny JJ, Chin SS, Milewski Y, Albers MW, Gordon ML, Marder K.

Mov Disord. 2005 May;20(5):610-3.


Potentiation of progesterone receptor-mediated transcription by the immunosuppressant FK506.

Tai PK, Albers MW, McDonnell DP, Chang H, Schreiber SL, Faber LE.

Biochemistry. 1994 Sep 6;33(35):10666-71.


A mammalian protein targeted by G1-arresting rapamycin-receptor complex.

Brown EJ, Albers MW, Shin TB, Ichikawa K, Keith CT, Lane WS, Schreiber SL.

Nature. 1994 Jun 30;369(6483):756-8.


Light-regulated, tissue-specific immunophilins in a higher plant.

Luan S, Albers MW, Schreiber SL.

Proc Natl Acad Sci U S A. 1994 Feb 1;91(3):984-8.


An FKBP-rapamycin-sensitive, cyclin-dependent kinase activity that correlates with the FKBP-rapamycin-induced G1 arrest point in MG-63 cells.

Albers MW, Brown EJ, Tanaka A, Williams RT, Hall FL, Schreiber SL.

Ann N Y Acad Sci. 1993 Nov 30;696:54-62. No abstract available.


FKBP54, a novel FK506-binding protein in avian progesterone receptor complexes and HeLa extracts.

Smith DF, Albers MW, Schreiber SL, Leach KL, Deibel MR Jr.

J Biol Chem. 1993 Nov 15;268(32):24270-3.


FKBP-rapamycin inhibits a cyclin-dependent kinase activity and a cyclin D1-Cdk association in early G1 of an osteosarcoma cell line.

Albers MW, Williams RT, Brown EJ, Tanaka A, Hall FL, Schreiber SL.

J Biol Chem. 1993 Oct 25;268(30):22825-9.


P59 (FK506 binding protein 59) interaction with heat shock proteins is highly conserved and may involve proteins other than steroid receptors.

Tai PK, Chang H, Albers MW, Schreiber SL, Toft DO, Faber LE.

Biochemistry. 1993 Aug 31;32(34):8842-7.


Effects of cyclosporin A and FK506 on Fc epsilon receptor type I-initiated increases in cytokine mRNA in mouse bone marrow-derived progenitor mast cells: resistance to FK506 is associated with a deficiency in FK506-binding protein FKBP12.

Kaye RE, Fruman DA, Bierer BE, Albers MW, Zydowsky LD, Ho SI, Jin YJ, Castells MC, Schreiber SL, Walsh CT, et al.

Proc Natl Acad Sci U S A. 1992 Sep 15;89(18):8542-6.


Association of a 59-kilodalton immunophilin with the glucocorticoid receptor complex.

Tai PK, Albers MW, Chang H, Faber LE, Schreiber SL.

Science. 1992 May 29;256(5061):1315-8.


Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity.

Liu J, Albers MW, Wandless TJ, Luan S, Alberg DG, Belshaw PJ, Cohen P, MacKintosh C, Klee CB, Schreiber SL.

Biochemistry. 1992 Apr 28;31(16):3896-901.


Immunophilin-ligand complexes as probes of intracellular signaling pathways.

Schreiber SL, Liu J, Albers MW, Karmacharya R, Koh E, Martin PK, Rosen MK, Standaert RF, Wandless TJ.

Transplant Proc. 1991 Dec;23(6):2839-44. Review. No abstract available.


Hepatotrophic properties in dogs of human FKBP, the binding protein for FK506 and rapamycin.

Starzl TE, Schreiber SL, Albers MW, Porter KA, Foglieni CS, Francavilla A.

Transplantation. 1991 Oct;52(4):751-3. No abstract available.


Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13.

Jin YJ, Albers MW, Lane WS, Bierer BE, Schreiber SL, Burakoff SJ.

Proc Natl Acad Sci U S A. 1991 Aug 1;88(15):6677-81.


Immunophilin ligands demonstrate common features of signal transduction leading to exocytosis or transcription.

Hultsch T, Albers MW, Schreiber SL, Hohman RJ.

Proc Natl Acad Sci U S A. 1991 Jul 15;88(14):6229-33.


Relationship of FKBP to PKCI-2.

Albers MW, Liu J, Schreiber SL.

Nature. 1991 Jun 13;351(6327):527. No abstract available.


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