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Items: 1 to 50 of 62

1.

Emerging Biomarkers in Cutaneous Melanoma.

Eisenstein A, Gonzalez EC, Raghunathan R, Xu X, Wu M, McLean EO, McGee J, Ryu B, Alani RM.

Mol Diagn Ther. 2018 Apr;22(2):203-218. doi: 10.1007/s40291-018-0318-z. Review.

PMID:
29411301
2.

Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors.

Kalin JH, Wu M, Gomez AV, Song Y, Das J, Hayward D, Adejola N, Wu M, Panova I, Chung HJ, Kim E, Roberts HJ, Roberts JM, Prusevich P, Jeliazkov JR, Roy Burman SS, Fairall L, Milano C, Eroglu A, Proby CM, Dinkova-Kostova AT, Hancock WW, Gray JJ, Bradner JE, Valente S, Mai A, Anders NM, Rudek MA, Hu Y, Ryu B, Schwabe JWR, Mattevi A, Alani RM, Cole PA.

Nat Commun. 2018 Jan 4;9(1):53. doi: 10.1038/s41467-017-02242-4.

3.

Quantitative assessment of neuropilin-2 as a simple and sensitive diagnostic assay for spitzoid melanocytic lesions.

Eisenstein A, Panova IP, Chung HJ, Goldberg LJ, Zhang Q, Lazova R, Bhawan J, Busam KJ, Symanowski JT, Alani RM, Ryu B.

Melanoma Res. 2018 Feb;28(1):71-75. doi: 10.1097/CMR.0000000000000416.

4.

Skin cancer screening: recommendations for data-driven screening guidelines and a review of the US Preventive Services Task Force controversy.

Johnson MM, Leachman SA, Aspinwall LG, Cranmer LD, Curiel-Lewandrowski C, Sondak VK, Stemwedel CE, Swetter SM, Vetto J, Bowles T, Dellavalle RP, Geskin LJ, Grossman D, Grossmann KF, Hawkes JE, Jeter JM, Kim CC, Kirkwood JM, Mangold AR, Meyskens F, Ming ME, Nelson KC, Piepkorn M, Pollack BP, Robinson JK, Sober AJ, Trotter S, Venna SS, Agarwala S, Alani R, Averbook B, Bar A, Becevic M, Box N, E Carson W 3rd, Cassidy PB, Chen SC, Chu EY, Ellis DL, Ferris LK, Fisher DE, Kendra K, Lawson DH, Leming PD, Margolin KA, Markovic S, Martini MC, Miller D, Sahni D, Sharfman WH, Stein J, Stratigos AJ, Tarhini A, Taylor MH, Wisco OJ, Wong MK.

Melanoma Manag. 2017 Mar;4(1):13-37. doi: 10.2217/mmt-2016-0022. Epub 2017 Mar 1. Review.

5.

Notch3 signaling-mediated melanoma-endothelial crosstalk regulates melanoma stem-like cell homeostasis and niche morphogenesis.

Hsu MY, Yang MH, Schnegg CI, Hwang S, Ryu B, Alani RM.

Lab Invest. 2017 Jun;97(6):725-736. doi: 10.1038/labinvest.2017.1. Epub 2017 Feb 6.

6.

Paving a New Path Towards Academic Medicine-A Novel Approach to Graduate Medical Education in the United States.

Alani RM, Larson A, Falanga V.

Acad Med. 2016 Aug;91(8):1039-40. doi: 10.1097/ACM.0000000000001269. No abstract available.

PMID:
27465087
7.

A microfluidic Transwell to study chemotaxis.

Zhang C, Barrios MP, Alani RM, Cabodi M, Wong JY.

Exp Cell Res. 2016 Mar 15;342(2):159-65. doi: 10.1016/j.yexcr.2016.03.010. Epub 2016 Mar 14.

PMID:
26988422
8.

Neuropilin-2 promotes melanoma growth and progression in vivo.

Moriarty WF, Kim E, Gerber SA, Hammers H, Alani RM.

Melanoma Res. 2016 Aug;26(4):321-8. doi: 10.1097/CMR.0000000000000190.

PMID:
26881875
9.

A simple engineered platform reveals different modes of tumor-microenvironmental cell interaction.

Zhang C, Shenk EM, Blaha LC, Ryu B, Alani RM, Cabodi M, Wong JY.

Biofabrication. 2015 Dec 30;8(1):015001. doi: 10.1088/1758-5090/8/1/015001.

10.

A prospective study on red blood cell transfusion related hyperkalemia in critically ill patients.

Raza S, Ali Baig M, Chang C, Dabas R, Akhtar M, Khan A, Nemani K, Alani R, Majumder O, Gazizova N, Biswas S, Patel P, Al-Hilli JA, Shad Y, Berger BJ, Zaman M.

J Clin Med Res. 2015 Jun;7(6):417-21. doi: 10.14740/jocmr2123w. Epub 2015 Apr 8.

11.

Detection of circulating tumor DNA in early- and late-stage human malignancies.

Bettegowda C, Sausen M, Leary RJ, Kinde I, Wang Y, Agrawal N, Bartlett BR, Wang H, Luber B, Alani RM, Antonarakis ES, Azad NS, Bardelli A, Brem H, Cameron JL, Lee CC, Fecher LA, Gallia GL, Gibbs P, Le D, Giuntoli RL, Goggins M, Hogarty MD, Holdhoff M, Hong SM, Jiao Y, Juhl HH, Kim JJ, Siravegna G, Laheru DA, Lauricella C, Lim M, Lipson EJ, Marie SK, Netto GJ, Oliner KS, Olivi A, Olsson L, Riggins GJ, Sartore-Bianchi A, Schmidt K, Shih lM, Oba-Shinjo SM, Siena S, Theodorescu D, Tie J, Harkins TT, Veronese S, Wang TL, Weingart JD, Wolfgang CL, Wood LD, Xing D, Hruban RH, Wu J, Allen PJ, Schmidt CM, Choti MA, Velculescu VE, Kinzler KW, Vogelstein B, Papadopoulos N, Diaz LA Jr.

Sci Transl Med. 2014 Feb 19;6(224):224ra24. doi: 10.1126/scitranslmed.3007094.

12.

Neuropilin-2 gene expression correlates with malignant progression in cutaneous melanoma.

Rossi M, Tuck J, Kim OJ, Panova I, Symanowski JT, Mahalingam M, Riker AI, Alani RM, Ryu B.

Br J Dermatol. 2014 Aug;171(2):403-8. doi: 10.1111/bjd.12801. Epub 2014 Jun 11.

PMID:
24359286
13.

MC1R is a potent regulator of PTEN after UV exposure in melanocytes.

Cao J, Wan L, Hacker E, Dai X, Lenna S, Jimenez-Cervantes C, Wang Y, Leslie NR, Xu GX, Widlund HR, Ryu B, Alani RM, Dutton-Regester K, Goding CR, Hayward NK, Wei W, Cui R.

Mol Cell. 2013 Aug 22;51(4):409-22. doi: 10.1016/j.molcel.2013.08.010.

14.

Notch signaling mediates melanoma-endothelial cell communication and melanoma cell migration.

Howard JD, Moriarty WF, Park J, Riedy K, Panova IP, Chung CH, Suh KY, Levchenko A, Alani RM.

Pigment Cell Melanoma Res. 2013 Sep;26(5):697-707. doi: 10.1111/pcmr.12131. Epub 2013 Jul 19.

PMID:
23773728
15.

Selective inhibition of p300 HAT blocks cell cycle progression, induces cellular senescence, and inhibits the DNA damage response in melanoma cells.

Yan G, Eller MS, Elm C, Larocca CA, Ryu B, Panova IP, Dancy BM, Bowers EM, Meyers D, Lareau L, Cole PA, Taverna SD, Alani RM.

J Invest Dermatol. 2013 Oct;133(10):2444-2452. doi: 10.1038/jid.2013.187. Epub 2013 Apr 18.

16.

MicroRNAs as an emerging target for melanoma therapy.

Ryu B, Hwang S, Alani RM.

J Invest Dermatol. 2013 May;133(5):1137-9. doi: 10.1038/jid.2012.505.

17.

DNA repair gene variants in relation to overall cancer risk: a population-based study.

Alberg AJ, Jorgensen TJ, Ruczinski I, Wheless L, Shugart YY, Berthier-Schaad Y, Kessing B, Hoffman-Bolton J, Helzlsouer KJ, Kao WH, Francis L, Alani RM, Smith MW, Strickland PT.

Carcinogenesis. 2013 Jan;34(1):86-92. doi: 10.1093/carcin/bgs304. Epub 2012 Oct 1.

18.

A population-based study of hedgehog pathway gene variants in relation to the dual risk of basal cell carcinoma plus another cancer.

Jorgensen TJ, Ruczinski I, Yao Shugart Y, Wheless L, Berthier Schaad Y, Kessing B, Hoffman-Bolton J, Helzlsouer KJ, Kao WH, Francis L, Alani RM, Strickland PT, Smith MW, Alberg AJ.

Cancer Epidemiol. 2012 Oct;36(5):e288-93. doi: 10.1016/j.canep.2012.05.001. Epub 2012 Jun 5.

19.

A population-based study of DNA repair gene variants in relation to non-melanoma skin cancer as a marker of a cancer-prone phenotype.

Ruczinski I, Jorgensen TJ, Shugart YY, Schaad YB, Kessing B, Hoffman-Bolton J, Helzlsouer KJ, Kao WH, Wheless L, Francis L, Alani RM, Strickland PT, Smith MW, Alberg AJ.

Carcinogenesis. 2012 Sep;33(9):1692-8. doi: 10.1093/carcin/bgs170. Epub 2012 May 11.

20.

A community-based study of nucleotide excision repair polymorphisms in relation to the risk of non-melanoma skin cancer.

Wheless L, Kistner-Griffin E, Jorgensen TJ, Ruczinski I, Berthier-Schaad Y, Kessing B, Hoffman-Bolton J, Francis L, Shugart YY, Strickland PT, Kao WH, Alani RM, Smith MW, Alberg AJ.

J Invest Dermatol. 2012 May;132(5):1354-62. doi: 10.1038/jid.2012.4. Epub 2012 Feb 16.

21.

Neuropilin-2: a novel biomarker for malignant melanoma?

Rushing EC, Stine MJ, Hahn SJ, Shea S, Eller MS, Naif A, Khanna S, Westra WH, Jungbluth AA, Busam KJ, Mahalingam M, Alani RM.

Hum Pathol. 2012 Mar;43(3):381-9. doi: 10.1016/j.humpath.2011.05.008. Epub 2011 Aug 15.

22.

Sun-seeking behavior to increase cutaneous vitamin D synthesis: when prevention messages conflict.

Clipp SL, Burke A, Hoffman-Bolton J, Alani R, Liégeois NJ, Alberg AJ.

Public Health Rep. 2011 Jul-Aug;126(4):533-9.

23.

Dynamic acetylation of all lysine-4 trimethylated histone H3 is evolutionarily conserved and mediated by p300/CBP.

Crump NT, Hazzalin CA, Bowers EM, Alani RM, Cole PA, Mahadevan LC.

Proc Natl Acad Sci U S A. 2011 May 10;108(19):7814-9. doi: 10.1073/pnas.1100099108. Epub 2011 Apr 25.

24.

Expression of Id-1 is regulated by MCAM/MUC18: a missing link in melanoma progression.

Zigler M, Villares GJ, Dobroff AS, Wang H, Huang L, Braeuer RR, Kamiya T, Melnikova VO, Song R, Friedman R, Alani RM, Bar-Eli M.

Cancer Res. 2011 May 15;71(10):3494-504. doi: 10.1158/0008-5472.CAN-10-3555. Epub 2011 Apr 5.

25.

Global analysis of BRAFV600E target genes in human melanocytes identifies matrix metalloproteinase-1 as a critical mediator of melanoma growth.

Ryu B, Moriarty WF, Stine MJ, DeLuca A, Kim DS, Meeker AK, Grills LD, Switzer RA, Eller MS, Alani RM.

J Invest Dermatol. 2011 Jul;131(7):1579-83. doi: 10.1038/jid.2011.65. Epub 2011 Mar 31. No abstract available.

26.

Integration of genotypic and phenotypic screening reveals molecular mediators of melanoma-stromal interaction.

Stine MJ, Wang CJ, Moriarty WF, Ryu B, Cheong R, Westra WH, Levchenko A, Alani RM.

Cancer Res. 2011 Apr 1;71(7):2433-44. doi: 10.1158/0008-5472.CAN-10-1875. Epub 2011 Feb 15.

27.

Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor.

Bowers EM, Yan G, Mukherjee C, Orry A, Wang L, Holbert MA, Crump NT, Hazzalin CA, Liszczak G, Yuan H, Larocca C, Saldanha SA, Abagyan R, Sun Y, Meyers DJ, Marmorstein R, Mahadevan LC, Alani RM, Cole PA.

Chem Biol. 2010 May 28;17(5):471-82. doi: 10.1016/j.chembiol.2010.03.006.

28.

Id1 promotes tumor cell migration in nonsmall cell lung cancers.

Bhattacharya R, Kowalski J, Larson AR, Brock M, Alani RM.

J Oncol. 2010;2010:856105. doi: 10.1155/2010/856105. Epub 2010 Apr 18.

29.

Cigarette smoking and malignant melanoma: a case-control study.

Kessides MC, Wheless L, Hoffman-Bolton J, Clipp S, Alani RM, Alberg AJ.

J Am Acad Dermatol. 2011 Jan;64(1):84-90. doi: 10.1016/j.jaad.2010.01.041. Epub 2010 Mar 23.

30.

Glyceraldehyde-3-phosphate dehydrogenase expression is altered by hypoxia in melanoma cells and primary human melanocytes.

Silverthorn CF, Alani RM.

Melanoma Res. 2010 Feb;20(1):61-3. doi: 10.1097/CMR.0b013e328333d8c2. No abstract available.

PMID:
20051782
31.

The association between skin characteristics and skin cancer prevention behaviors.

Wheless L, Ruczinski I, Alani RM, Clipp S, Hoffman-Bolton J, Jorgensen TJ, Liégeois NJ, Strickland PT, Alberg AJ.

Cancer Epidemiol Biomarkers Prev. 2009 Oct;18(10):2613-9. doi: 10.1158/1055-9965.EPI-09-0383. Epub 2009 Sep 15.

32.

Melanoma biomarkers: current status and vision for the future.

Larson AR, Konat E, Alani RM.

Nat Clin Pract Oncol. 2009 Feb;6(2):105-17. doi: 10.1038/ncponc1296. Epub 2008 Dec 23. Review.

PMID:
19107110
33.

Nonmelanoma skin cancer and risk for subsequent malignancy.

Chen J, Ruczinski I, Jorgensen TJ, Yenokyan G, Yao Y, Alani R, Liégeois NJ, Hoffman SC, Hoffman-Bolton J, Strickland PT, Helzlsouer KJ, Alberg AJ.

J Natl Cancer Inst. 2008 Sep 3;100(17):1215-22. doi: 10.1093/jnci/djn260. Epub 2008 Aug 26.

34.

BRAF kinase in melanoma development and progression.

DeLuca AM, Srinivas A, Alani RM.

Expert Rev Mol Med. 2008 Feb 18;10:e6. doi: 10.1017/S1462399408000604. Review.

PMID:
18279546
35.

Id1 delays senescence of primary human melanocytes.

Cummings SD, Ryu B, Samuels MA, Yu X, Meeker AK, Healey MA, Alani RM.

Mol Carcinog. 2008 Sep;47(9):653-9. doi: 10.1002/mc.20422.

36.
37.

Id1 expression is transcriptionally regulated in radial growth phase melanomas.

Ryu B, Kim DS, DeLuca AM, Healey MA, Dunlap S, Fackler MJ, Herman J, Alani RM.

Int J Cancer. 2007 Oct 15;121(8):1705-9.

38.

Toward a molecular classification of melanoma.

Fecher LA, Cummings SD, Keefe MJ, Alani RM.

J Clin Oncol. 2007 Apr 20;25(12):1606-20. Review.

PMID:
17443002
39.

Synthesis and evaluation of a potent and selective cell-permeable p300 histone acetyltransferase inhibitor.

Zheng Y, Balasubramanyam K, Cebrat M, Buck D, Guidez F, Zelent A, Alani RM, Cole PA.

J Am Chem Soc. 2005 Dec 14;127(49):17182-3.

PMID:
16332055
40.

Histone acetyltransferase activity of p300 is required for transcriptional repression by the promyelocytic leukemia zinc finger protein.

Guidez F, Howell L, Isalan M, Cebrat M, Alani RM, Ivins S, Hormaeche I, McConnell MJ, Pierce S, Cole PA, Licht J, Zelent A.

Mol Cell Biol. 2005 Jul;25(13):5552-66.

41.

Malignant transformation of human cells by constitutive expression of platelet-derived growth factor-BB.

Govindarajan B, Shah A, Cohen C, Arnold RS, Schechner J, Chung J, Mercurio AM, Alani R, Ryu B, Fan CY, Cuezva JM, Martinez M, Arbiser JL.

J Biol Chem. 2005 Apr 8;280(14):13936-43. Epub 2005 Feb 4.

42.

Tumor angiogenesis in mice and men.

Alani RM, Silverthorn CF, Orosz K.

Cancer Biol Ther. 2004 Jun;3(6):498-500. Epub 2004 Jun 19. Review.

PMID:
15153806
43.

High-efficiency stable gene transduction in primary human melanocytes using a lentiviral expression system.

Dunlap S, Yu X, Cheng L, Civin CI, Alani RM.

J Invest Dermatol. 2004 Feb;122(2):549-51. No abstract available.

44.

Selective HAT inhibitors as mechanistic tools for protein acetylation.

Zheng Y, Thompson PR, Cebrat M, Wang L, Devlin MK, Alani RM, Cole PA.

Methods Enzymol. 2004;376:188-99. Review. No abstract available.

PMID:
14975306
45.

Disruption of Id1 reveals major differences in angiogenesis between transplanted and autochthonous tumors.

Sikder H, Huso DL, Zhang H, Wang B, Ryu B, Hwang ST, Powell JD, Alani RM.

Cancer Cell. 2003 Oct;4(4):291-9.

46.

Id proteins in cell growth and tumorigenesis.

Sikder HA, Devlin MK, Dunlap S, Ryu B, Alani RM.

Cancer Cell. 2003 Jun;3(6):525-30. Review.

47.

Wiring the angiogenic switch: Ras, Myc, and Thrombospondin-1.

Volpert OV, Alani RM.

Cancer Cell. 2003 Mar;3(3):199-200.

48.

Id1 regulates angiogenesis through transcriptional repression of thrombospondin-1.

Volpert OV, Pili R, Sikder HA, Nelius T, Zaichuk T, Morris C, Shiflett CB, Devlin MK, Conant K, Alani RM.

Cancer Cell. 2002 Dec;2(6):473-83.

49.

Acupuncture granulomas.

Alani RM, Busam K.

J Am Acad Dermatol. 2001 Dec;45(6 Suppl):S225-6.

PMID:
11712067
50.

The transcriptional repressor of p16/Ink4a, Id1, is up-regulated in early melanomas.

Polsky D, Young AZ, Busam KJ, Alani RM.

Cancer Res. 2001 Aug 15;61(16):6008-11.

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