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Items: 21


Emerging Intraoperative Imaging Modalities to Improve Surgical Precision.

Alam IS, Steinberg I, Vermesh O, van den Berg NS, Rosenthal EL, van Dam GM, Ntziachristos V, Gambhir SS, Hernot S, Rogalla S.

Mol Imaging Biol. 2018 Jun 18. doi: 10.1007/s11307-018-1227-6. [Epub ahead of print]


The Utility of [18F]DASA-23 for Molecular Imaging of Prostate Cancer with Positron Emission Tomography.

Beinat C, Haywood T, Chen YS, Patel CB, Alam IS, Murty S, Gambhir SS.

Mol Imaging Biol. 2018 May 7. doi: 10.1007/s11307-018-1194-y. [Epub ahead of print]


Imaging activated T cells predicts response to cancer vaccines.

Alam IS, Mayer AT, Sagiv-Barfi I, Wang K, Vermesh O, Czerwinski DK, Johnson EM, James ML, Levy R, Gambhir SS.

J Clin Invest. 2018 Jun 1;128(6):2569-2580. doi: 10.1172/JCI98509. Epub 2018 May 14.


[18F]FSPG-PET reveals increased cystine/glutamate antiporter (xc-) activity in a mouse model of multiple sclerosis.

Hoehne A, James ML, Alam IS, Ronald JA, Schneider B, D'Souza A, Witney TH, Andrews LE, Cropper HC, Behera D, Gowrishankar G, Ding Z, Wyss-Coray T, Chin FT, Biswal S, Gambhir SS.

J Neuroinflammation. 2018 Feb 22;15(1):55. doi: 10.1186/s12974-018-1080-1.


Intraoperative Molecular Imaging in Lung Cancer: The State of the Art and the Future.

Rogalla S, Joosten SCM, Alam IS, Gambhir SS, Vermesh O.

Mol Ther. 2018 Feb 7;26(2):338-341. doi: 10.1016/j.ymthe.2018.01.013. Epub 2018 Feb 2. No abstract available.


Eradication of spontaneous malignancy by local immunotherapy.

Sagiv-Barfi I, Czerwinski DK, Levy S, Alam IS, Mayer AT, Gambhir SS, Levy R.

Sci Transl Med. 2018 Jan 31;10(426). pii: eaan4488. doi: 10.1126/scitranslmed.aan4488.


A PET Imaging Strategy to Visualize Activated T Cells in Acute Graft-versus-Host Disease Elicited by Allogenic Hematopoietic Cell Transplant.

Ronald JA, Kim BS, Gowrishankar G, Namavari M, Alam IS, D'Souza A, Nishikii H, Chuang HY, Ilovich O, Lin CF, Reeves R, Shuhendler A, Hoehne A, Chan CT, Baker J, Yaghoubi SS, VanBrocklin HF, Hawkins R, Franc BL, Jivan S, Slater JB, Verdin EF, Gao KT, Benjamin J, Negrin R, Gambhir SS.

Cancer Res. 2017 Jun 1;77(11):2893-2902. doi: 10.1158/0008-5472.CAN-16-2953.


Development of [18F]DASA-23 for Imaging Tumor Glycolysis Through Noninvasive Measurement of Pyruvate Kinase M2.

Beinat C, Alam IS, James ML, Srinivasan A, Gambhir SS.

Mol Imaging Biol. 2017 Oct;19(5):665-672. doi: 10.1007/s11307-017-1068-8.


Rapid Imaging of Tumor Cell Death In Vivo Using the C2A Domain of Synaptotagmin-I.

Neves AA, Xie B, Fawcett S, Alam IS, Witney TH, de Backer MM, Summers J, Hughes W, McGuire S, Soloviev D, Miller J, Howat WJ, Hu DE, Rodrigues TB, Lewis DY, Brindle KM.

J Nucl Med. 2017 Jun;58(6):881-887. doi: 10.2967/jnumed.116.183004. Epub 2017 Feb 16.


Correction: Microwave gallium-68 radiochemistry for kinetically stable bis(thiosemicarbazone) complexes: structural investigations and cellular uptake under hypoxia.

Alam IS, Arrowsmith RL, Cortezon-Tamarit F, Twyman F, Kociok-Köhn G, Botchway SW, Dilworth JR, Carroll L, Aboagye EO, Pascu SI.

Dalton Trans. 2016 Feb 28;45(8):3650. doi: 10.1039/c6dt90021f. No abstract available.


Microwave gallium-68 radiochemistry for kinetically stable bis(thiosemicarbazone) complexes: structural investigations and cellular uptake under hypoxia.

Alam IS, Arrowsmith RL, Cortezon-Tamarit F, Twyman F, Kociok-Köhn G, Botchway SW, Dilworth JR, Carroll L, Aboagye EO, Pascu SI.

Dalton Trans. 2016 Jan 7;45(1):144-55. doi: 10.1039/c5dt02537k. Erratum in: Dalton Trans. 2016 Feb 28;45(8):3650.


Radiopharmaceuticals as probes to characterize tumour tissue.

Alam IS, Arshad MA, Nguyen QD, Aboagye EO.

Eur J Nucl Med Mol Imaging. 2015 Apr;42(4):537-61. doi: 10.1007/s00259-014-2984-3. Epub 2015 Feb 3. Review.


Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress.

Schug ZT, Peck B, Jones DT, Zhang Q, Grosskurth S, Alam IS, Goodwin LM, Smethurst E, Mason S, Blyth K, McGarry L, James D, Shanks E, Kalna G, Saunders RE, Jiang M, Howell M, Lassailly F, Thin MZ, Spencer-Dene B, Stamp G, van den Broek NJ, Mackay G, Bulusu V, Kamphorst JJ, Tardito S, Strachan D, Harris AL, Aboagye EO, Critchlow SE, Wakelam MJ, Schulze A, Gottlieb E.

Cancer Cell. 2015 Jan 12;27(1):57-71. doi: 10.1016/j.ccell.2014.12.002.


Preclinical evaluation of 3-18F-fluoro-2,2-dimethylpropionic acid as an imaging agent for tumor detection.

Witney TH, Pisaneschi F, Alam IS, Trousil S, Kaliszczak M, Twyman F, Brickute D, Nguyen QD, Schug Z, Gottlieb E, Aboagye EO.

J Nucl Med. 2014 Sep;55(9):1506-12. doi: 10.2967/jnumed.114.140343. Epub 2014 Jul 10. Erratum in: J Nucl Med. 2014 Nov;55(11):1914.


A novel radiotracer to image glycogen metabolism in tumors by positron emission tomography.

Witney TH, Carroll L, Alam IS, Chandrashekran A, Nguyen QD, Sala R, Harris R, DeBerardinis RJ, Agarwal R, Aboagye EO.

Cancer Res. 2014 Mar 1;74(5):1319-28. doi: 10.1158/0008-5472.CAN-13-2768.


PET imaging with multimodal upconversion nanoparticles.

Gallo J, Alam IS, Jin J, Gu YJ, Aboagye EO, Wong WT, Long NJ.

Dalton Trans. 2014 Apr 14;43(14):5535-45. doi: 10.1039/c3dt53095g. Epub 2014 Feb 18.


Radiolabeled RGD tracer kinetics annotates differential αvβ 3 integrin expression linked to cell intrinsic and vessel expression.

Alam IS, Witney TH, Tomasi G, Carroll L, Twyman FJ, Nguyen QD, Aboagye EO.

Mol Imaging Biol. 2014 Aug;16(4):558-66. doi: 10.1007/s11307-013-0710-3. Epub 2013 Dec 6.


Evaluation of deuterated 18F- and 11C-labeled choline analogs for cancer detection by positron emission tomography.

Witney TH, Alam IS, Turton DR, Smith G, Carroll L, Brickute D, Twyman FJ, Nguyen QD, Tomasi G, Awais RO, Aboagye EO.

Clin Cancer Res. 2012 Feb 15;18(4):1063-72. doi: 10.1158/1078-0432.CCR-11-2462. Epub 2012 Jan 10.


Imaging sialylated tumor cell glycans in vivo.

Neves AA, Stöckmann H, Harmston RR, Pryor HJ, Alam IS, Ireland-Zecchini H, Lewis DY, Lyons SK, Leeper FJ, Brindle KM.

FASEB J. 2011 Aug;25(8):2528-37. doi: 10.1096/fj.10-178590. Epub 2011 Apr 14.


Comparison of the C2A domain of synaptotagmin-I and annexin-V as probes for detecting cell death.

Alam IS, Neves AA, Witney TH, Boren J, Brindle KM.

Bioconjug Chem. 2010 May 19;21(5):884-91. doi: 10.1021/bc9004415.


Organizational structure and productive efficiency of non-profit hospitals.

Alam IS, Granderson G.

Adv Health Econ Health Serv Res. 2008;18:63-88. No abstract available.


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