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Items: 45

1.

Heme Oxygenase-1 protects astroglia against manganese-induced oxidative injury by regulating mitochondrial quality control.

Gorojod RM, Alaimo A, Porte Alcon S, Martinez JH, Cortina ME, Vazquez ES, Kotler ML.

Toxicol Lett. 2018 Oct 1;295:357-368. doi: 10.1016/j.toxlet.2018.07.045. Epub 2018 Jul 21.

PMID:
30040983
2.

Calmodulin: A Multitasking Protein in Kv7.2 Potassium Channel Functions.

Alaimo A, Villarroel A.

Biomolecules. 2018 Jul 18;8(3). pii: E57. doi: 10.3390/biom8030057. Review.

3.

Alpha-synuclein mitochondrial interaction leads to irreversible translocation and complex I impairment.

Martínez JH, Fuentes F, Vanasco V, Alvarez S, Alaimo A, Cassina A, Coluccio Leskow F, Velazquez F.

Arch Biochem Biophys. 2018 Aug 1;651:1-12. doi: 10.1016/j.abb.2018.04.018. Epub 2018 Apr 25.

PMID:
29702063
4.

Drp-1 dependent mitochondrial fragmentation and protective autophagy in dopaminergic SH-SY5Y cells overexpressing alpha-synuclein.

Martinez JH, Alaimo A, Gorojod RM, Porte Alcon S, Fuentes F, Coluccio Leskow F, Kotler ML.

Mol Cell Neurosci. 2018 Apr;88:107-117. doi: 10.1016/j.mcn.2018.01.004. Epub 2018 Feb 3.

PMID:
29414102
5.

Structural and Magnetic Variations in a Family of Isoskeletal, Oximate-Bridged {MnIV2 MIII } Complexes (MIII =Mn, Gd, Dy).

Alaimo AA, Worrell A, Gupta SD, Abboud KA, Lampropoulos C, Christou G, Stamatatos TC.

Chemistry. 2018 Feb 21;24(11):2588-2592. doi: 10.1002/chem.201706098. Epub 2018 Jan 25.

PMID:
29315881
6.

Calmodulin confers calcium sensitivity to the stability of the distal intracellular assembly domain of Kv7.2 channels.

Alaimo A, Nuñez E, Aivar P, Fernández-Orth J, Gomis-Perez C, Bernardo-Seisdedos G, Malo C, Villarroel A.

Sci Rep. 2017 Oct 18;7(1):13425. doi: 10.1038/s41598-017-13811-4.

7.

Structural Diversities in Heterometallic Mn-Ca Cluster Chemistry from the Use of Salicylhydroxamic Acid: {MnIII4Ca2}, {MnII/III6Ca2}, {MnIII/IV8Ca}, and {MnIII8Ca2} Complexes with Relevance to Both High- and Low-Valent States of the Oxygen-Evolving Complex.

Alaimo AA, Koumousi ES, Cunha-Silva L, McCormick LJ, Teat SJ, Psycharis V, Raptopoulou CP, Mukherjee S, Li C, Gupta SD, Escuer A, Christou G, Stamatatos TC.

Inorg Chem. 2017 Sep 5;56(17):10760-10774. doi: 10.1021/acs.inorgchem.7b01740. Epub 2017 Aug 17.

8.

Consensus Document of the Italian Association of Hospital Cardiologists (ANMCO), Italian Society of Pediatric Cardiology (SICP), and Italian Society of Gynaecologists and Obstetrics (SIGO): pregnancy and congenital heart diseases.

Bianca I, Geraci G, Gulizia MM, Egidy Assenza G, Barone C, Campisi M, Alaimo A, Adorisio R, Comoglio F, Favilli S, Agnoletti G, Carmina MG, Chessa M, Sarubbi B, Mongiovì M, Russo MG, Bianca S, Canzone G, Bonvicini M, Viora E, Poli M.

Eur Heart J Suppl. 2017 May;19(Suppl D):D256-D292. doi: 10.1093/eurheartj/sux032. Epub 2017 May 2.

9.

Interplay between lysosomal, mitochondrial and death receptor pathways during manganese-induced apoptosis in glial cells.

Gorojod RM, Alaimo A, Porte Alcon S, Saravia F, Kotler ML.

Arch Toxicol. 2017 Sep;91(9):3065-3078. doi: 10.1007/s00204-017-1936-7. Epub 2017 Apr 4.

PMID:
28378122
10.

Early-onset epileptic encephalopathy caused by a reduced sensitivity of Kv7.2 potassium channels to phosphatidylinositol 4,5-bisphosphate.

Soldovieri MV, Ambrosino P, Mosca I, De Maria M, Moretto E, Miceli F, Alaimo A, Iraci N, Manocchio L, Medoro A, Passafaro M, Taglialatela M.

Sci Rep. 2016 Dec 1;6:38167. doi: 10.1038/srep38167.

11.

[ANMCO/SICP/SIGO Consensus document: Pregnancy and congenital heart disease].

Bianca I, Geraci G, Gulizia MM, Egidy-Assenza G, Barone C, Campisi M, Alaimo A, Adorisio R, Comoglio F, Favilli S, Agnoletti G, Carmina MG, Chessa M, Sarubbi B, Mongiovì M, Russo MG, Bianca S, Canzone G, Bonvicini M, Viora E, Poli M.

G Ital Cardiol (Rome). 2016 Sep;17(9):687-755. doi: 10.1714/2448.25662. Italian.

PMID:
27869889
12.

[Cardiovascular Disease In Children With Ckd].

Corrado C, Pellitteri V, Alaimo A, Galione MA, Mongiovì R, Maringhini S.

G Ital Nefrol. 2015 Nov-Dec;32(6). pii: gin/32.6.10. Italian.

PMID:
26845213
13.

Uncoupling PIP2-calmodulin regulation of Kv7.2 channels by an assembly destabilizing epileptogenic mutation.

Alberdi A, Gomis-Perez C, Bernardo-Seisdedos G, Alaimo A, Malo C, Aldaregia J, Lopez-Robles C, Areso P, Butz E, Wahl-Schott C, Villarroel A.

J Cell Sci. 2015 Nov 1;128(21):4014-23. doi: 10.1242/jcs.176420. Epub 2015 Sep 10.

14.

Glial alterations from early to late stages in a model of Alzheimer's disease: Evidence of autophagy involvement in Aβ internalization.

Pomilio C, Pavia P, Gorojod RM, Vinuesa A, Alaimo A, Galvan V, Kotler ML, Beauquis J, Saravia F.

Hippocampus. 2016 Feb;26(2):194-210. doi: 10.1002/hipo.22503. Epub 2015 Sep 4.

15.

The autophagic- lysosomal pathway determines the fate of glial cells under manganese- induced oxidative stress conditions.

Gorojod RM, Alaimo A, Porte Alcon S, Pomilio C, Saravia F, Kotler ML.

Free Radic Biol Med. 2015 Oct;87:237-51. doi: 10.1016/j.freeradbiomed.2015.06.034. Epub 2015 Jul 8.

PMID:
26163003
16.

An unconventional calmodulin-anchoring site within the AB module of Kv7.2 channels.

Gomis-Perez C, Alaimo A, Fernandez-Orth J, Alberdi A, Aivar-Mateo P, Bernardo-Seisdedos G, Malo C, Areso P, Felipe A, Villarroel A.

J Cell Sci. 2015 Aug 15;128(16):3155-63. doi: 10.1242/jcs.174128. Epub 2015 Jul 6.

17.

Epilepsy-causing mutations in Kv7.2 C-terminus affect binding and functional modulation by calmodulin.

Ambrosino P, Alaimo A, Bartollino S, Manocchio L, De Maria M, Mosca I, Gomis-Perez C, Alberdi A, Scambia G, Lesca G, Villarroel A, Taglialatela M, Soldovieri MV.

Biochim Biophys Acta. 2015 Sep;1852(9):1856-66. doi: 10.1016/j.bbadis.2015.06.012. Epub 2015 Jun 12.

18.

Emissive {Mn4(III)Ca} clusters with square pyramidal topologies: syntheses and structural, spectroscopic, and physicochemical characterization.

Alaimo AA, Takahashi D, Cunha-Silva L, Christou G, Stamatatos TC.

Inorg Chem. 2015 Mar 2;54(5):2137-51. doi: 10.1021/ic502492x. Epub 2014 Dec 5.

PMID:
25478943
19.

Clicked bis-PEG-peptide conjugates for studying calmodulin-Kv7.2 channel binding.

Bonache MA, Alaimo A, Malo C, Millet O, Villarroel A, González-Muñiz R.

Org Biomol Chem. 2014 Nov 28;12(44):8877-87. doi: 10.1039/c4ob01338g.

PMID:
25264745
20.

A molecular survey of Rickettsia felis in fleas from cats and dogs in Sicily (Southern Italy).

Giudice E, Di Pietro S, Alaimo A, Blanda V, Lelli R, Francaviglia F, Caracappa S, Torina A.

PLoS One. 2014 Sep 9;9(9):e106820. doi: 10.1371/journal.pone.0106820. eCollection 2014.

21.

The ever changing moods of calmodulin: how structural plasticity entails transductional adaptability.

Villarroel A, Taglialatela M, Bernardo-Seisdedos G, Alaimo A, Agirre J, Alberdi A, Gomis-Perez C, Soldovieri MV, Ambrosino P, Malo C, Areso P.

J Mol Biol. 2014 Jul 29;426(15):2717-35. doi: 10.1016/j.jmb.2014.05.016. Epub 2014 May 22. Review.

PMID:
24857860
22.

Deregulation of mitochondria-shaping proteins Opa-1 and Drp-1 in manganese-induced apoptosis.

Alaimo A, Gorojod RM, Beauquis J, Muñoz MJ, Saravia F, Kotler ML.

PLoS One. 2014 Mar 14;9(3):e91848. doi: 10.1371/journal.pone.0091848. eCollection 2014.

23.

Pivoting between calmodulin lobes triggered by calcium in the Kv7.2/calmodulin complex.

Alaimo A, Alberdi A, Gomis-Perez C, Fernández-Orth J, Bernardo-Seisdedos G, Malo C, Millet O, Areso P, Villarroel A.

PLoS One. 2014 Jan 28;9(1):e86711. doi: 10.1371/journal.pone.0086711. eCollection 2014.

24.

Mechanostructure and composition of highly reproducible decellularized liver matrices.

Mattei G, Di Patria V, Tirella A, Alaimo A, Elia G, Corti A, Paolicchi A, Ahluwalia A.

Acta Biomater. 2014 Feb;10(2):875-82. doi: 10.1016/j.actbio.2013.10.023. Epub 2013 Oct 30.

PMID:
24184179
25.

Manganese induces mitochondrial dynamics impairment and apoptotic cell death: a study in human Gli36 cells.

Alaimo A, Gorojod RM, Miglietta EA, Villarreal A, Ramos AJ, Kotler ML.

Neurosci Lett. 2013 Oct 25;554:76-81. doi: 10.1016/j.neulet.2013.08.061. Epub 2013 Sep 8.

PMID:
24021799
26.

Primary percutaneous coronary intervention for acute myocardial infarction in a pediatric patient with giant coronary aneurysm due to Kawasaki disease.

Mongiovì M, Alaimo A, Vernuccio F, Pieri D.

Congenit Heart Dis. 2014 Jan-Feb;9(1):E16-8. doi: 10.1111/chd.12056. Epub 2013 Apr 22.

PMID:
23601472
27.

Numerical analysis of piezoelectric active repair in the presence of frictional contact conditions.

Alaimo A, Milazzo A, Orlando C, Messineo A.

Sensors (Basel). 2013 Apr 2;13(4):4390-403. doi: 10.3390/s130404390.

28.

The use of dansyl-calmodulin to study interactions with channels and other proteins.

Alaimo A, Malo C, Areso P, Aloria K, Millet O, Villarroel A.

Methods Mol Biol. 2013;998:217-31. doi: 10.1007/978-1-62703-351-0_17.

PMID:
23529433
29.

Cooperativity between calmodulin-binding sites in Kv7.2 channels.

Alaimo A, Alberdi A, Gomis-Perez C, Fernández-Orth J, Gómez-Posada JC, Areso P, Villarroel A.

J Cell Sci. 2013 Jan 1;126(Pt 1):244-53. doi: 10.1242/jcs.114082. Epub 2012 Nov 30.

30.

Surface expression and subunit specific control of steady protein levels by the Kv7.2 helix A-B linker.

Aivar P, Fernández-Orth J, Gomis-Perez C, Alberdi A, Alaimo A, Rodríguez MS, Giraldez T, Miranda P, Areso P, Villarroel A.

PLoS One. 2012;7(10):e47263. doi: 10.1371/journal.pone.0047263. Epub 2012 Oct 24.

31.

Kv7 channels can function without constitutive calmodulin tethering.

Gómez-Posada JC, Aivar P, Alberdi A, Alaimo A, Etxeberría A, Fernández-Orth J, Zamalloa T, Roura-Ferrer M, Villace P, Areso P, Casis O, Villarroel A.

PLoS One. 2011;6(9):e25508. doi: 10.1371/journal.pone.0025508. Epub 2011 Sep 28.

32.

The extrinsic and intrinsic apoptotic pathways are involved in manganese toxicity in rat astrocytoma C6 cells.

Alaimo A, Gorojod RM, Kotler ML.

Neurochem Int. 2011 Aug;59(2):297-308. doi: 10.1016/j.neuint.2011.06.001. Epub 2011 Jun 16.

PMID:
21704098
33.

Selective interaction of syntaxin 1A with KCNQ2: possible implications for specific modulation of presynaptic activity.

Regev N, Degani-Katzav N, Korngreen A, Etzioni A, Siloni S, Alaimo A, Chikvashvili D, Villarroel A, Attali B, Lotan I.

PLoS One. 2009 Aug 13;4(8):e6586. doi: 10.1371/journal.pone.0006586.

34.

Calmodulin activation limits the rate of KCNQ2 K+ channel exit from the endoplasmic reticulum.

Alaimo A, Gómez-Posada JC, Aivar P, Etxeberría A, Rodriguez-Alfaro JA, Areso P, Villarroel A.

J Biol Chem. 2009 Jul 31;284(31):20668-75. doi: 10.1074/jbc.M109.019539. Epub 2009 Jun 3.

35.

Antitumor effects of curcumin and structurally beta-diketone modified analogs on multidrug resistant cancer cells.

Simoni D, Rizzi M, Rondanin R, Baruchello R, Marchetti P, Invidiata FP, Labbozzetta M, Poma P, Carina V, Notarbartolo M, Alaimo A, D'Alessandro N.

Bioorg Med Chem Lett. 2008 Jan 15;18(2):845-9. Epub 2007 Nov 13.

PMID:
18039573
36.

Calmodulin regulates the trafficking of KCNQ2 potassium channels.

Etxeberria A, Aivar P, Rodriguez-Alfaro JA, Alaimo A, Villacé P, Gómez-Posada JC, Areso P, Villarroel A.

FASEB J. 2008 Apr;22(4):1135-43. Epub 2007 Nov 9.

PMID:
17993630
37.

The antitumor activities of curcumin and of its isoxazole analogue are not affected by multiple gene expression changes in an MDR model of the MCF-7 breast cancer cell line: analysis of the possible molecular basis.

Poma P, Notarbartolo M, Labbozzetta M, Maurici A, Carina V, Alaimo A, Rizzi M, Simoni D, D'Alessandro N.

Int J Mol Med. 2007 Sep;20(3):329-35.

PMID:
17671737
38.

Antitumor effects of the novel NF-kappaB inhibitor dehydroxymethyl-epoxyquinomicin on human hepatic cancer cells: analysis of synergy with cisplatin and of possible correlation with inhibition of pro-survival genes and IL-6 production.

Poma P, Notarbartolo M, Labbozzetta M, Sanguedolce R, Alaimo A, Carina V, Maurici A, Cusimano A, Cervello M, D'Alessandro N.

Int J Oncol. 2006 Apr;28(4):923-30.

PMID:
16525642
39.

Noninvasive pacemaker stress echocardiography for diagnosis of coronary artery disease: a multicenter study.

Picano E, Alaimo A, Chubuchny V, Plonska E, Baldo V, Baldini U, Pauletti M, Perticucci R, Fonseca L, Villarraga HR, Emanuelli C, Miracapillo G, Hoffmann E, De Nes M.

J Am Coll Cardiol. 2002 Oct 2;40(7):1305-10.

40.

[Role of calcitonin and kinesitherapy in the treatment of senile osteoarthrosis].

Dainotto F, Alaimo A, Bonelli M, Miozzi S.

Recenti Prog Med. 1985 Oct;76(10):520-2. Italian. No abstract available.

PMID:
4089305
41.

[Treatment of arterial hypertension with a calcium-channel blocking agent, nicardipine hydrochloride].

Cascone A, Ferrari F, Alaimo A, Daprati A, Cascone G.

Boll Chim Farm. 1985 May;124(5):37S-42S. Italian. No abstract available.

PMID:
4052244
42.

[Treatment of patients with congestive heart failure with coenzyme Q10 in an open trial].

Cascone A, Cascone G, Alaimo A.

Boll Chim Farm. 1985 May;124(5):43S-52S. Italian. No abstract available.

PMID:
3902057
43.

[Coenzyme Q10 in myocardial insufficiency].

Cascone A, Alaimo A, Ferrari F, Cascone G.

Boll Chim Farm. 1984 Aug;123(8):55S-60S. Italian. No abstract available.

PMID:
6525251
44.

[Congenital anophthalmos. Apropos of 2 cases with tomodensitometric examination].

Hullo A, Alaimo A, Fraisse J, Lauras B, Maugery J.

Bull Soc Ophtalmol Fr. 1982 Dec;82(12):1523-5. French. No abstract available.

PMID:
7184650
45.

[Experimental research on the physiopathology of circulation during artificial hibernation. II. Rise in venous potential].

BRANCADORO G, URSINI M, ALAIMO A.

G Ital Chir. 1954 Nov;10(11):887-91. Italian. No abstract available.

PMID:
14366322

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