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Items: 23


Distal respiratory tract viral infections in young children trigger a marked increase in alveolar mast cells.

Andersson CK, Shikhagaie M, Mori M, Al-Garawi A, Reed JL, Humbles AA, Welliver R, Mauad T, Bjermer L, Jordana M, Erjefält JS.

ERJ Open Res. 2018 Nov 23;4(4). pii: 00038-2018. doi: 10.1183/23120541.00038-2018. eCollection 2018 Oct.


Expression network analysis reveals cord blood vitamin D-associated genes affecting risk of early life wheeze.

Mirzakhani H, Al-Garawi AA, Carey VJ, Qiu W, Litonjua AA, Weiss ST.

Thorax. 2019 Feb;74(2):200-202. doi: 10.1136/thoraxjnl-2018-211962. Epub 2018 Jul 18.


Integration of metabolomic and transcriptomic networks in pregnant women reveals biological pathways and predictive signatures associated with preeclampsia.

Kelly RS, Croteau-Chonka DC, Dahlin A, Mirzakhani H, Wu AC, Wan ES, McGeachie MJ, Qiu W, Sordillo JE, Al-Garawi A, Gray KJ, McElrath TF, Carey VJ, Clish CB, Litonjua AA, Weiss ST, Lasky-Su JA.

Metabolomics. 2017 Jan;13(1). pii: 7. doi: 10.1007/s11306-016-1149-8. Epub 2016 Dec 12.


The Role of Vitamin D in the Transcriptional Program of Human Pregnancy.

Al-Garawi A, Carey VJ, Chhabra D, Mirzakhani H, Morrow J, Lasky-Su J, Qiu W, Laranjo N, Litonjua AA, Weiss ST.

PLoS One. 2016 Oct 6;11(10):e0163832. doi: 10.1371/journal.pone.0163832. eCollection 2016.


The metabolomics of asthma control: a promising link between genetics and disease.

McGeachie MJ, Dahlin A, Qiu W, Croteau-Chonka DC, Savage J, Wu AC, Wan ES, Sordillo JE, Al-Garawi A, Martinez FD, Strunk RC, Lemanske RF Jr, Liu AH, Raby BA, Weiss S, Clish CB, Lasky-Su JA.

Immun Inflamm Dis. 2015 Sep;3(3):224-38. doi: 10.1002/iid3.61. Epub 2015 May 7.


Therapeutic potential of anti-IL-6 therapies for granulocytic airway inflammation in asthma.

Chu DK, Al-Garawi A, Llop-Guevara A, Pillai RA, Radford K, Shen P, Walker TD, Goncharova S, Calhoun WJ, Nair P, Jordana M.

Allergy Asthma Clin Immunol. 2015 Apr 12;11(1):14. doi: 10.1186/s13223-015-0081-1. eCollection 2015.


Vitamin D and the development of allergic disease: how important is it?

Mirzakhani H, Al-Garawi A, Weiss ST, Litonjua AA.

Clin Exp Allergy. 2015 Jan;45(1):114-25. doi: 10.1111/cea.12430. Review.


Critical role of natural killer cells in lung immunopathology during influenza infection in mice.

Abdul-Careem MF, Mian MF, Yue G, Gillgrass A, Chenoweth MJ, Barra NG, Chew MV, Chan T, Al-Garawi AA, Jordana M, Ashkar AA.

J Infect Dis. 2012 Jul 15;206(2):167-77. doi: 10.1093/infdis/jis340. Epub 2012 May 4.


Shifting of immune responsiveness to house dust mite by influenza A infection: genomic insights.

Al-Garawi A, Husain M, Ilieva D, Humbles AA, Kolbeck R, Stampfli MR, O'Byrne PM, Coyle AJ, Jordana M.

J Immunol. 2012 Jan 15;188(2):832-43. doi: 10.4049/jimmunol.1102349. Epub 2011 Dec 14.


FimH, a TLR4 ligand, induces innate antiviral responses in the lung leading to protection against lethal influenza infection in mice.

Abdul-Careem MF, Firoz Mian M, Gillgrass AE, Chenoweth MJ, Barra NG, Chan T, Al-Garawi AA, Chew MV, Yue G, van Roojen N, Xing Z, Ashkar AA.

Antiviral Res. 2011 Nov;92(2):346-55. doi: 10.1016/j.antiviral.2011.09.004. Epub 2011 Sep 14.


Influenza A facilitates sensitization to house dust mite in infant mice leading to an asthma phenotype in adulthood.

Al-Garawi A, Fattouh R, Botelho F, Walker TD, Goncharova S, Moore CL, Mori M, Erjefalt JS, Chu DK, Humbles AA, Kolbeck R, Stampfli MR, O'Byrne PM, Coyle AJ, Jordana M.

Mucosal Immunol. 2011 Nov;4(6):682-94. doi: 10.1038/mi.2011.35. Epub 2011 Aug 31.


Eosinophils are dispensable for allergic remodeling and immunity in a model of house dust mite-induced airway disease.

Fattouh R, Al-Garawi A, Fattouh M, Arias K, Walker TD, Goncharova S, Coyle AJ, Humbles AA, Jordana M.

Am J Respir Crit Care Med. 2011 Jan 15;183(2):179-88. doi: 10.1164/rccm.200905-0736OC. Epub 2010 Aug 23.


Acute, but not resolved, influenza A infection enhances susceptibility to house dust mite-induced allergic disease.

Al-Garawi AA, Fattouh R, Walker TD, Jamula EB, Botelho F, Goncharova S, Reed J, Stampfli MR, O'Byrne PM, Coyle AJ, Jordana M.

J Immunol. 2009 Mar 1;182(5):3095-104. doi: 10.4049/jimmunol.0802837.


Inhibition of NF-kappaB activation reduces the tissue effects of transgenic IL-13.

Chapoval SP, Al-Garawi A, Lora JM, Strickland I, Ma B, Lee PJ, Homer RJ, Ghosh S, Coyle AJ, Elias JA.

J Immunol. 2007 Nov 15;179(10):7030-41.


Coordinated involvement of mast cells and T cells in allergic mucosal inflammation: critical role of the CC chemokine ligand 1:CCR8 axis.

Gonzalo JA, Qiu Y, Lora JM, Al-Garawi A, Villeval JL, Boyce JA, Martinez-A C, Marquez G, Goya I, Hamid Q, Fraser CC, Picarella D, Cote-Sierra J, Hodge MR, Gutierrez-Ramos JC, Kolbeck R, Coyle AJ.

J Immunol. 2007 Aug 1;179(3):1740-50.


Cysteinyl leukotrienes regulate Th2 cell-dependent pulmonary inflammation.

Kim DC, Hsu FI, Barrett NA, Friend DS, Grenningloh R, Ho IC, Al-Garawi A, Lora JM, Lam BK, Austen KF, Kanaoka Y.

J Immunol. 2006 Apr 1;176(7):4440-8.


FcepsilonRI-dependent gene expression in human mast cells is differentially controlled by T helper type 2 cytokines.

Lora JM, Al-Garawi A, Pickard MD, Price KS, Bagga S, Sicoli J, Hodge MR, Gutiérrez-Ramos JC, Briskin MJ, Boyce JA.

J Allergy Clin Immunol. 2003 Dec;112(6):1119-26.


Activated human hepatic stellate cells express the renin-angiotensin system and synthesize angiotensin II.

Bataller R, Sancho-Bru P, Ginès P, Lora JM, Al-Garawi A, Solé M, Colmenero J, Nicolás JM, Jiménez W, Weich N, Gutiérrez-Ramos JC, Arroyo V, Rodés J.

Gastroenterology. 2003 Jul;125(1):117-25.


Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1.

Grenier JM, Wang L, Manji GA, Huang WJ, Al-Garawi A, Kelly R, Carlson A, Merriam S, Lora JM, Briskin M, DiStefano PS, Bertin J.

FEBS Lett. 2002 Oct 23;530(1-3):73-8.


PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing.

Wang L, Manji GA, Grenier JM, Al-Garawi A, Merriam S, Lora JM, Geddes BJ, Briskin M, DiStefano PS, Bertin J.

J Biol Chem. 2002 Aug 16;277(33):29874-80. Epub 2002 May 17.


The murine CCR3 receptor regulates both the role of eosinophils and mast cells in allergen-induced airway inflammation and hyperresponsiveness.

Humbles AA, Lu B, Friend DS, Okinaga S, Lora J, Al-Garawi A, Martin TR, Gerard NP, Gerard C.

Proc Natl Acad Sci U S A. 2002 Feb 5;99(3):1479-84.


PYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-kappa B.

Manji GA, Wang L, Geddes BJ, Brown M, Merriam S, Al-Garawi A, Mak S, Lora JM, Briskin M, Jurman M, Cao J, DiStefano PS, Bertin J.

J Biol Chem. 2002 Mar 29;277(13):11570-5. Epub 2002 Jan 10.


ICOS is critical for T helper cell-mediated lung mucosal inflammatory responses.

Gonzalo JA, Tian J, Delaney T, Corcoran J, Rottman JB, Lora J, Al-garawi A, Kroczek R, Gutierrez-Ramos JC, Coyle AJ.

Nat Immunol. 2001 Jul;2(7):597-604.


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