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Items: 13

1.

Synthesis of marine-derived 3-alkylpyridinium alkaloids with potent antiprotozoal activity.

Rodenko B, Al-Salabi MI, Teka IA, Ho W, El-Sabbagh N, Ali JA, Ibrahim HM, Wanner MJ, Koomen GJ, de Koning HP.

ACS Med Chem Lett. 2011 Oct 5;2(12):901-6. doi: 10.1021/ml200160k. eCollection 2011 Dec 8.

2.

The diamidine diminazene aceturate is a substrate for the high-affinity pentamidine transporter: implications for the development of high resistance levels in trypanosomes.

Teka IA, Kazibwe AJ, El-Sabbagh N, Al-Salabi MI, Ward CP, Eze AA, Munday JC, Mäser P, Matovu E, Barrett MP, de Koning HP.

Mol Pharmacol. 2011 Jul;80(1):110-6. doi: 10.1124/mol.111.071555. Epub 2011 Mar 24.

3.

Symmetrical choline-derived dications display strong anti-kinetoplastid activity.

Ibrahim HM, Al-Salabi MI, El Sabbagh N, Quashie NB, Alkhaldi AA, Escale R, Smith TK, Vial HJ, de Koning HP.

J Antimicrob Chemother. 2011 Jan;66(1):111-25. doi: 10.1093/jac/dkq401. Epub 2010 Nov 14.

4.

Evaluation of nucleoside hydrolase inhibitors for treatment of African trypanosomiasis.

Berg M, Kohl L, Van der Veken P, Joossens J, Al-Salabi MI, Castagna V, Giannese F, Cos P, Versées W, Steyaert J, Grellier P, Haemers A, Degano M, Maes L, de Koning HP, Augustyns K.

Antimicrob Agents Chemother. 2010 May;54(5):1900-8. doi: 10.1128/AAC.01787-09. Epub 2010 Mar 1.

5.

Predictive computational models of substrate binding by a nucleoside transporter.

Collar CJ, Al-Salabi MI, Stewart ML, Barrett MP, Wilson WD, de Koning HP.

J Biol Chem. 2009 Dec 4;284(49):34028-35. doi: 10.1074/jbc.M109.049726. Epub 2009 Oct 5.

6.

Molecular interactions underlying the unusually high adenosine affinity of a novel Trypanosoma brucei nucleoside transporter.

Al-Salabi MI, Wallace LJ, Lüscher A, Mäser P, Candlish D, Rodenko B, Gould MK, Jabeen I, Ajith SN, de Koning HP.

Mol Pharmacol. 2007 Mar;71(3):921-9. Epub 2006 Dec 21.

PMID:
17185380
7.

Trypanosoma brucei: a survey of pyrimidine transport activities.

Gudin S, Quashie NB, Candlish D, Al-Salabi MI, Jarvis SM, Ranford-Cartwright LC, de Koning HP.

Exp Parasitol. 2006 Oct;114(2):118-25. Epub 2006 Apr 18.

PMID:
16620810
8.

Purine nucleobase transport in amastigotes of Leishmania mexicana: involvement in allopurinol uptake.

Al-Salabi MI, de Koning HP.

Antimicrob Agents Chemother. 2005 Sep;49(9):3682-9.

9.

Identification of the first pyrimidine nucleobase transporter in Leishmania: similarities with the Trypanosoma brucei U1 transporter and antileishmanial activity of uracil analogues.

Papageorgiou IG, Yakob L, Al Salabi MI, Diallinas G, Soteriadou KP, De Koning HP.

Parasitology. 2005 Mar;130(Pt 3):275-83.

PMID:
15796010
10.

Trypanosoma brucei: expression of multiple purine transporters prevents the development of allopurinol resistance.

Natto MJ, Wallace LJ, Candlish D, Al-Salabi MI, Coutts SE, de Koning HP.

Exp Parasitol. 2005 Feb;109(2):80-6. Epub 2005 Jan 8.

PMID:
15687014
11.

Identification and characterisation of high affinity nucleoside and nucleobase transporters in Toxoplasma gondii.

De Koning HP, Al-Salabi MI, Cohen AM, Coombs GH, Wastling JM.

Int J Parasitol. 2003 Jul 30;33(8):821-31.

PMID:
12865082
12.

Cloning, heterologous expression, and in situ characterization of the first high affinity nucleobase transporter from a protozoan.

Burchmore RJ, Wallace LJ, Candlish D, Al-Salabi MI, Beal PR, Barrett MP, Baldwin SA, de Koning HP.

J Biol Chem. 2003 Jun 27;278(26):23502-7. Epub 2003 Apr 21.

13.

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