Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 12

1.

Neurobiology and therapeutic applications of neurotoxins targeting transmitter release.

Ovsepian SV, O'Leary VB, Ayvazyan NM, Al-Sabi A, Ntziachristos V, Dolly JO.

Pharmacol Ther. 2019 Jan;193:135-155. doi: 10.1016/j.pharmthera.2018.08.016. Epub 2018 Aug 25. Review.

PMID:
30149105
2.

A Rational Design of a Selective Inhibitor for Kv1.1 Channels Prevalent in Demyelinated Nerves That Improves Their Impaired Axonal Conduction.

Al-Sabi A, Daly D, Hoefer P, Kinsella GK, Metais C, Pickering M, Herron C, Kaza SK, Nolan K, Dolly JO.

J Med Chem. 2017 Mar 23;60(6):2245-2256. doi: 10.1021/acs.jmedchem.6b01262. Epub 2017 Mar 13.

PMID:
28225274
3.

Porphyrin derivatives as potent and selective blockers of neuronal Kv1 channels.

Daly D, Al-Sabi A, Kinsella GK, Nolan K, Dolly JO.

Chem Commun (Camb). 2015 Jan 21;51(6):1066-9. doi: 10.1039/c4cc05639f.

PMID:
25435252
4.

Disruption of myelin leads to ectopic expression of K(V)1.1 channels with abnormal conductivity of optic nerve axons in a cuprizone-induced model of demyelination.

Bagchi B, Al-Sabi A, Kaza S, Scholz D, O'Leary VB, Dolly JO, Ovsepian SV.

PLoS One. 2014 Feb 3;9(2):e87736. doi: 10.1371/journal.pone.0087736. eCollection 2014.

5.

Sodium channel selectivity and conduction: prokaryotes have devised their own molecular strategy.

Finol-Urdaneta RK, Wang Y, Al-Sabi A, Zhao C, Noskov SY, French RJ.

J Gen Physiol. 2014 Feb;143(2):157-71. doi: 10.1085/jgp.201311037. Epub 2014 Jan 13.

6.

Pharmacological characteristics of Kv1.1- and Kv1.2-containing channels are influenced by the stoichiometry and positioning of their α subunits.

Al-Sabi A, Kaza SK, Dolly JO, Wang J.

Biochem J. 2013 Aug 15;454(1):101-8. doi: 10.1042/BJ20130297.

PMID:
23725331
7.

Position-dependent attenuation by Kv1.6 of N-type inactivation of Kv1.4-containing channels.

Al-Sabi A, Kaza S, Le Berre M, O'Hara L, Bodeker M, Wang J, Dolly JO.

Biochem J. 2011 Sep 1;438(2):389-96. doi: 10.1042/BJ20102169.

PMID:
21352098
8.

Multiple, distributed interactions of μ-conotoxin PIIIA associated with broad targeting among voltage-gated sodium channels.

McArthur JR, Ostroumov V, Al-Sabi A, McMaster D, French RJ.

Biochemistry. 2011 Jan 11;50(1):116-24. Epub 2010 Dec 10.

PMID:
21110521
9.

Arrangement of Kv1 alpha subunits dictates sensitivity to tetraethylammonium.

Al-Sabi A, Shamotienko O, Dhochartaigh SN, Muniyappa N, Le Berre M, Shaban H, Wang J, Sack JT, Dolly JO.

J Gen Physiol. 2010 Sep;136(3):273-82. doi: 10.1085/jgp.200910398.

10.

Identification of a novel pharmacophore for peptide toxins interacting with K+ channels.

Verdier L, Al-Sabi A, Rivier JE, Olivera BM, Terlau H, Carlomagno T.

J Biol Chem. 2005 Jun 3;280(22):21246-55. Epub 2005 Mar 30.

11.

KappaM-conotoxin RIIIK, structural and functional novelty in a K+ channel antagonist.

Al-Sabi A, Lennartz D, Ferber M, Gulyas J, Rivier JE, Olivera BM, Carlomagno T, Terlau H.

Biochemistry. 2004 Jul 13;43(27):8625-35.

PMID:
15236570
12.

Identification of a mammalian target of kappaM-conotoxin RIIIK.

Ferber M, Al-Sabi A, Stocker M, Olivera BM, Terlau H.

Toxicon. 2004 Jun 15;43(8):915-21.

PMID:
15208025

Supplemental Content

Loading ...
Support Center