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Items: 50

1.

Extracellular brain pH with or without hypoxia is a marker of profound metabolic derangement and increased mortality after traumatic brain injury.

Timofeev I, Nortje J, Al-Rawi PG, Hutchinson PJ, Gupta AK.

J Cereb Blood Flow Metab. 2013 Mar;33(3):422-7. doi: 10.1038/jcbfm.2012.186. Epub 2012 Dec 12.

2.

Interaction between brain chemistry and physiology after traumatic brain injury: impact of autoregulation and microdialysis catheter location.

Timofeev I, Czosnyka M, Carpenter KL, Nortje J, Kirkpatrick PJ, Al-Rawi PG, Menon DK, Pickard JD, Gupta AK, Hutchinson PJ.

J Neurotrauma. 2011 Jun;28(6):849-60. doi: 10.1089/neu.2010.1656.

3.

Cerebral extracellular chemistry and outcome following traumatic brain injury: a microdialysis study of 223 patients.

Timofeev I, Carpenter KL, Nortje J, Al-Rawi PG, O'Connell MT, Czosnyka M, Smielewski P, Pickard JD, Menon DK, Kirkpatrick PJ, Gupta AK, Hutchinson PJ.

Brain. 2011 Feb;134(Pt 2):484-94. doi: 10.1093/brain/awq353. Epub 2011 Jan 18.

PMID:
21247930
4.

Improved cerebrovascular reactivity following low flow EC/IC bypass in patients with occlusive carotid disease.

Patel HC, McNamara IR, Al-Rawi PG, Kirkpatrick PJ.

Br J Neurosurg. 2010 Apr;24(2):179-84. doi: 10.3109/02688690903536603.

PMID:
20210532
5.

Hypertonic saline in patients with poor-grade subarachnoid hemorrhage improves cerebral blood flow, brain tissue oxygen, and pH.

Al-Rawi PG, Tseng MY, Richards HK, Nortje J, Timofeev I, Matta BF, Hutchinson PJ, Kirkpatrick PJ.

Stroke. 2010 Jan;41(1):122-8. doi: 10.1161/STROKEAHA.109.560698. Epub 2009 Nov 12.

PMID:
19910550
6.

A combined microdialysis and FDG-PET study of glucose metabolism in head injury.

Hutchinson PJ, O'Connell MT, Seal A, Nortje J, Timofeev I, Al-Rawi PG, Coles JP, Fryer TD, Menon DK, Pickard JD, Carpenter KL.

Acta Neurochir (Wien). 2009 Jan;151(1):51-61; discussion 61. doi: 10.1007/s00701-008-0169-1. Epub 2008 Dec 20.

PMID:
19099177
7.

Nitric oxide in acute brain injury: a pilot study of NO(x) concentrations in human brain microdialysates and their relationship with energy metabolism.

Carpenter KL, Timofeev I, Al-Rawi PG, Menon DK, Pickard JD, Hutchinson PJ.

Acta Neurochir Suppl. 2008;102:207-13.

PMID:
19388318
8.

Ventriculostomy for control of raised ICP in acute traumatic brain injury.

Timofeev I, Dahyot-Fizelier C, Keong N, Nortje J, Al-Rawi PG, Czosnyka M, Menon DK, Kirkpatrick PJ, Gupta AK, Hutchinson PJ.

Acta Neurochir Suppl. 2008;102:99-104.

PMID:
19388297
9.

Inflammation in human brain injury: intracerebral concentrations of IL-1alpha, IL-1beta, and their endogenous inhibitor IL-1ra.

Hutchinson PJ, O'Connell MT, Rothwell NJ, Hopkins SJ, Nortje J, Carpenter KL, Timofeev I, Al-Rawi PG, Menon DK, Pickard JD.

J Neurotrauma. 2007 Oct;24(10):1545-57.

PMID:
17970618
10.

Enhancement of cerebral blood flow using systemic hypertonic saline therapy improves outcome in patients with poor-grade spontaneous subarachnoid hemorrhage.

Tseng MY, Al-Rawi PG, Czosnyka M, Hutchinson PJ, Richards H, Pickard JD, Kirkpatrick PJ.

J Neurosurg. 2007 Aug;107(2):274-82.

PMID:
17695380
11.

Microdialysis in the management of hepatic encephalopathy.

Hutchinson PJ, Gimson A, Al-Rawi PG, O'Connell MT, Czosnyka M, Menon DK.

Neurocrit Care. 2006;5(3):202-5.

PMID:
17290089
12.

Microdialysis to monitor scalp flap viability.

Bodkin PA, Al-Rawi PG, Canal AC, Hutchinson PJ.

J Reconstr Microsurg. 2007 Jan;23(1):57. No abstract available.

PMID:
17230324
13.

A randomized trial of synthetic patch versus direct primary closure in carotid endarterectomy.

Al-Rawi PG, Turner CL, Waran V, Ng I, Kirkpatrick PJ.

Neurosurgery. 2006 Oct;59(4):822-8; discussion 828-9.

PMID:
17038946
14.

Tissue oxygen index: thresholds for cerebral ischemia using near-infrared spectroscopy.

Al-Rawi PG, Kirkpatrick PJ.

Stroke. 2006 Nov;37(11):2720-5. Epub 2006 Sep 28.

PMID:
17008623
15.

Near infrared spectroscopy in brain injury: today's perspective.

Al-Rawi PG.

Acta Neurochir Suppl. 2005;95:453-7. Review.

PMID:
16463900
16.

Glucose metabolism in traumatic brain injury: a combined microdialysis and [18F]-2-fluoro-2-deoxy-D-glucose-positron emission tomography (FDG-PET) study.

O'Connell MT, Seal A, Nortje J, Al-Rawi PG, Coles JP, Fryer TD, Menon DK, Pickard JD, Hutchinson PJ.

Acta Neurochir Suppl. 2005;95:165-8.

PMID:
16463843
17.

Cerebral blood flow augmentation in patients with severe subarachnoid haemorrhage.

Al-Rawi PG, Zygun D, Tseng MY, Hutchinson PJ, Matta BF, Kirkpatrick PJ.

Acta Neurochir Suppl. 2005;95:123-7.

PMID:
16463835
18.

Extracellular amino acid changes in patients during reversible cerebral ischaemia.

Kett-White R, O'Connell MT, Hutchinson PJ, Al-Rawi PG, Gupta AK, Pickard JD, Kirkpatrick PJ.

Acta Neurochir Suppl. 2005;95:83-8.

PMID:
16463826
19.

Cerebral microdialysis methodology--evaluation of 20 kDa and 100 kDa catheters.

Hutchinson PJ, O'Connell MT, Nortje J, Smith P, Al-Rawi PG, Gupta AK, Menon DK, Pickard JD.

Physiol Meas. 2005 Aug;26(4):423-8. Epub 2005 Apr 11.

PMID:
15886437
20.

Carotid endarterectomy impairs blood pressure homeostasis by reducing the physiologic baroreflex reserve.

Nouraei SA, Al-Rawi PG, Sigaudo-Roussel D, Giussani DA, Gaunt ME.

J Vasc Surg. 2005 Apr;41(4):631-7.

21.

Effect of cerebral perfusion pressure augmentation on regional oxygenation and metabolism after head injury.

Johnston AJ, Steiner LA, Coles JP, Chatfield DA, Fryer TD, Smielewski P, Hutchinson PJ, O'Connell MT, Al-Rawi PG, Aigbirihio FI, Clark JC, Pickard JD, Gupta AK, Menon DK.

Crit Care Med. 2005 Jan;33(1):189-95; discussion 255-7.

PMID:
15644668
22.

Hyperglycemia and brain tissue pH after traumatic brain injury.

Zygun DA, Steiner LA, Johnston AJ, Hutchinson PJ, Al-Rawi PG, Chatfield D, Kirkpatrick PJ, Menon DK, Gupta AK.

Neurosurgery. 2004 Oct;55(4):877-81; discussion 882.

PMID:
15458595
23.

Extracellular Brain pH and Outcome following Severe Traumatic Brain Injury.

Gupta AK, Zygun DA, Johnston AJ, Steiner LA, Al-Rawi PG, Chatfield D, Shepherd E, Kirkpatrick PJ, Hutchinson PJ, Menon DK.

J Neurotrauma. 2004 Jun;21(6):678-84.

PMID:
15253796
24.

Effect of lignocaine injection in carotid sinus on baroreceptor sensitivity during carotid endarterectomy.

Al-Rawi PG, Sigaudo-Roussel D, Gaunt ME.

J Vasc Surg. 2004 Jun;39(6):1288-94.

25.

Effect of cerebral perfusion pressure augmentation with dopamine and norepinephrine on global and focal brain oxygenation after traumatic brain injury.

Johnston AJ, Steiner LA, Chatfield DA, Coles JP, Hutchinson PJ, Al-Rawi PG, Menon DK, Gupta AK.

Intensive Care Med. 2004 May;30(5):791-7. Epub 2004 Mar 27.

PMID:
15048550
26.

Effects of propofol on cerebral oxygenation and metabolism after head injury.

Johnston AJ, Steiner LA, Chatfield DA, Coleman MR, Coles JP, Al-Rawi PG, Menon DK, Gupta AK.

Br J Anaesth. 2003 Dec;91(6):781-6.

27.

Measurement of changes in cytochrome oxidase redox state during obstructive sleep apnea using near-infrared spectroscopy.

McGown AD, Makker H, Elwell C, Al Rawi PG, Valipour A, Spiro SG.

Sleep. 2003 Sep;26(6):710-6.

PMID:
14572124
28.

Effect of hypertonic saline on cerebral blood flow in poor-grade patients with subarachnoid hemorrhage.

Tseng MY, Al-Rawi PG, Pickard JD, Rasulo FA, Kirkpatrick PJ.

Stroke. 2003 Jun;34(6):1389-96. Epub 2003 May 1.

PMID:
12730557
29.

Extracellular lactate/pyruvate and glutamate changes in patients during per-operative episodes of cerebral ischaemia.

Kett-White R, Hutchinson PJ, al-Rawi PG, Gupta AK, O'Connell MT, Pickard JD, Kirkpatrick PJ.

Acta Neurochir Suppl. 2002;81:363-5.

PMID:
12168348
30.

Clinical cerebral microdialysis--determining the true extracellular concentration.

Hutchinson PJ, O'Connell MT, al-Rawi PG, Kett-White R, Gupta AK, Kirkpatrick PJ, Pickard JD.

Acta Neurochir Suppl. 2002;81:359-62.

PMID:
12168347
31.

Cerebral oxygen and microdialysis monitoring during aneurysm surgery: effects of blood pressure, cerebrospinal fluid drainage, and temporary clipping on infarction.

Kett-White R, Hutchinson PJ, Al-Rawi PG, Czosnyka M, Gupta AK, Pickard JD, Kirkpatrick PJ.

J Neurosurg. 2002 Jun;96(6):1013-9.

PMID:
12066900
32.

Correlation between cerebral blood flow, substrate delivery, and metabolism in head injury: a combined microdialysis and triple oxygen positron emission tomography study.

Hutchinson PJ, Gupta AK, Fryer TF, Al-Rawi PG, Chatfield DA, Coles JP, O'Connell MT, Kett-White R, Minhas PS, Aigbirhio FI, Clark JC, Kirkpatrick PJ, Menon DK, Pickard JD.

J Cereb Blood Flow Metab. 2002 Jun;22(6):735-45.

PMID:
12045672
33.

Adverse cerebral events detected after subarachnoid hemorrhage using brain oxygen and microdialysis probes.

Kett-White R, Hutchinson PJ, Al-Rawi PG, Gupta AK, Pickard JD, Kirkpatrick PJ.

Neurosurgery. 2002 Jun;50(6):1213-21; discussion 1221-2.

PMID:
12015838
34.

Effect of hypothermia on brain tissue oxygenation in patients with severe head injury.

Gupta AK, Al-Rawi PG, Hutchinson PJ, Kirkpatrick PJ.

Br J Anaesth. 2002 Feb;88(2):188-92.

35.

Investigation of the effect of chlormethiazole on cerebral chemistry in neurosurgical patients: a combined study of microdialysis and a neuroprotective agent.

Hutchinson PJ, O'Connell MT, Coles JP, Chatfield DA, Coleman MR, Al-Rawi PG, Kett-White CR, Gupta AK, Menon DK, Boniface SJ, Heazell M, Kirkpatrick PJ, Pickard JD.

Br J Clin Pharmacol. 2002 Mar;53(3):275-83.

36.

Measurement of brain tissue oxygenation performed using positron emission tomography scanning to validate a novel monitoring method.

Gupta AK, Hutchinson PJ, Fryer T, Al-Rawi PG, Parry DA, Minhas PS, Kett-White R, Kirkpatrick PJ, Mathews JC, Downey S, Aigbirhio F, Clark J, Pickard JD, Menon DK.

J Neurosurg. 2002 Feb;96(2):263-8.

PMID:
11838800
37.

Increases in GABA concentrations during cerebral ischaemia: a microdialysis study of extracellular amino acids.

Hutchinson PJ, O'Connell MT, Al-Rawi PG, Kett-White CR, Gupta AK, Maskell LB, Pickard JD, Kirkpatrick PJ.

J Neurol Neurosurg Psychiatry. 2002 Jan;72(1):99-105.

38.
39.

On-line monitoring of substrate delivery and brain metabolism in head injury.

Hutchinson PJ, al-Rawi PG, O'Connell MT, Gupta AK, Maskell LB, Hutchinson DB, Pickard JD, Kirkpatrick PJ.

Acta Neurochir Suppl. 2000;76:431-5.

PMID:
11450061
40.

Head injury monitoring using cerebral microdialysis and Paratrend multiparameter sensors.

Hutchinson PJ, al-Rawi PG, O'Connell MT, Gupta AK, Maskell LB, Hutchinson DB, Pickard JD, Kirkpatrick PJ.

Zentralbl Neurochir. 2000;61(2):88-94.

PMID:
10986757
41.

Multiparameter brain tissue monitoring--correlation between parameters and identification of CPP thresholds.

al-Rawi PG, Hutchinson PJ, Gupta AK, Piechnik SK, Pickard JD, Kirkpatrick PJ.

Zentralbl Neurochir. 2000;61(2):74-9.

PMID:
10986755
42.

Clinical cerebral microdialysis: a methodological study.

Hutchinson PJ, O'Connell MT, Al-Rawi PG, Maskell LB, Kett-White R, Gupta AK, Richards HK, Hutchinson DB, Kirkpatrick PJ, Pickard JD.

J Neurosurg. 2000 Jul;93(1):37-43.

PMID:
10883903
43.

Biochemical changes related to hypoxia during cerebral aneurysm surgery: combined microdialysis and tissue oxygen monitoring: case report.

Hutchinson PJ, Al-Rawi PG, O'Connell MT, Gupta AK, Pickard JD, Kirkpatrick PJ.

Neurosurgery. 2000 Jan;46(1):201-5; discussion 205-6.

PMID:
10626951
44.

Monitoring of brain metabolism during aneurysm surgery using microdialysis and brain multiparameter sensors.

Hutchinson PJ, Al-Rawi PG, O'Connell MT, Gupta AK, Maskell LB, Hutchinson DB, Pickard JD, Kirkpatrick PJ.

Neurol Res. 1999 Jun;21(4):352-8.

PMID:
10406006
45.

Hemodynamic characterization of intracranial pressure plateau waves in head-injury patients.

Czosnyka M, Smielewski P, Piechnik S, Schmidt EA, Al-Rawi PG, Kirkpatrick PJ, Pickard JD.

J Neurosurg. 1999 Jul;91(1):11-9.

PMID:
10389874
46.

Critical closing pressure in cerebrovascular circulation.

Czosnyka M, Smielewski P, Piechnik S, Al-Rawi PG, Kirkpatrick PJ, Matta BF, Pickard JD.

J Neurol Neurosurg Psychiatry. 1999 May;66(5):606-11.

47.

Neuropathological findings after intracerebral implantation of microdialysis catheters in sheep forebrain.

Hutchinson PJ, O'Connell MT, Al-Rawi PG, Maskell LB, Gupta AK, Hutchinson DB, Pickard JD, Kirkpatrick PJ, Wharton SB.

Neuroreport. 1999 Feb 25;10(3):i. No abstract available.

PMID:
10208567
48.

Assessment of spatially resolved spectroscopy during cardiopulmonary bypass.

Al-Rawi PG, Smielewski P, Hobbiger H, Ghosh S, Kirkpatrick PJ.

J Biomed Opt. 1999 Apr;4(2):208-16.

49.

Preliminary evaluation of a prototype spatially resolved spectrometer.

al-Rawi PG, Smielewski P, Kirkpatrick PJ.

Acta Neurochir Suppl. 1998;71:255-7.

PMID:
9779199
50.

Use of near infrared spectroscopy for the clinical monitoring of adult brain.

Kirkpatrick PJ, Smielewski P, Lam JM, Al-Rawi PG.

J Biomed Opt. 1996 Oct;1(4):363-72. No abstract available.

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