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Items: 1 to 50 of 126

1.

Strain and sex-based glucocentric & behavioral differences between KK/HlJ and C57BL/6J mice.

Inglis A, Shibin S, Ubungen R, Farooq S, Mata P, Thiam J, Al-Mohanna FA, Collison KS.

Physiol Behav. 2019 Oct 15;210:112646. doi: 10.1016/j.physbeh.2019.112646. Epub 2019 Aug 7.

PMID:
31400379
2.

An atypical pulmonary fibrosis is associated with co-inheritance of mutations in the calcium binding protein genes S100A3 and S100A13.

Al-Mutairy EA, Imtiaz FA, Khalid M, Al Qattan S, Saleh S, Mahmoud LM, Al-Saif MM, Al-Haj L, Al-Enazi A, AlJebreen AM, Mohammed SF, Mobeireek AF, Alkattan K, Chisti MA, Luzina IG, Al-Owain M, Weheba I, Abdelsayed AM, Ramzan K, Janssen LJ, Conca W, Alaiya A, Collison KS, Meyer BF, Atamas SP, Khabar KS, Hasday JD, Al-Mohanna F.

Eur Respir J. 2019 Jul 18;54(1). pii: 1802041. doi: 10.1183/13993003.02041-2018. Print 2019 Jul.

3.

Bi-allelic Mutations in FAM149B1 Cause Abnormal Primary Cilium and a Range of Ciliopathy Phenotypes in Humans.

Shaheen R, Jiang N, Alzahrani F, Ewida N, Al-Sheddi T, Alobeid E, Musaev D, Stanley V, Hashem M, Ibrahim N, Abdulwahab F, Alshenqiti A, Sonmez FM, Saqati N, Alzaidan H, Al-Qattan MM, Al-Mohanna F, Gleeson JG, Alkuraya FS.

Am J Hum Genet. 2019 Apr 4;104(4):731-737. doi: 10.1016/j.ajhg.2019.02.018. Epub 2019 Mar 21.

PMID:
30905400
4.

Modifying inter-cistronic sequence significantly enhances IRES dependent second gene expression in bicistronic vector: Construction of optimised cassette for gene therapy of familial hypercholesterolemia.

Al-Allaf FA, Abduljaleel Z, Athar M, Taher MM, Khan W, Mehmet H, Colakogullari M, Apostolidou S, Bigger B, Waddington S, Coutelle C, Themis M, Al-Ahdal MN, Al-Mohanna FA, Al-Hassnan ZN, Bouazzaoui A.

Noncoding RNA Res. 2018 Nov 22;4(1):1-14. doi: 10.1016/j.ncrna.2018.11.005. eCollection 2019 Mar.

5.

Data on hypoxia-induced VEGF, leptin and NF-kB p65 expression.

Al-Anazi A, Parhar R, Saleh S, Al-Hijailan R, Inglis A, Al-Jufan M, Bazzi M, Hashmi S, Conca W, Collison K, Al-Mohanna F.

Data Brief. 2018 Nov 1;21:2395-2397. doi: 10.1016/j.dib.2018.10.147. eCollection 2018 Dec.

6.

Salts and energy balance: A special role for dietary salts in metabolic syndrome.

Brey CW, Akbari-Alavijeh S, Ling J, Sheagley J, Shaikh B, Al-Mohanna F, Wang Y, Gaugler R, Hashmi S.

Clin Nutr. 2018 Nov 3. pii: S0261-5614(18)32492-0. doi: 10.1016/j.clnu.2018.10.021. [Epub ahead of print] Review.

PMID:
30446179
7.

Interleukin-8 Activates Breast Cancer-Associated Adipocytes and Promotes Their Angiogenesis- and Tumorigenesis-Promoting Effects.

Al-Khalaf HH, Al-Harbi B, Al-Sayed A, Arafah M, Tulbah A, Jarman A, Al-Mohanna F, Aboussekhra A.

Mol Cell Biol. 2019 Jan 3;39(2). pii: e00332-18. doi: 10.1128/MCB.00332-18. Print 2019 Jan 15.

8.

Intracellular calcium and NF-kB regulate hypoxia-induced leptin, VEGF, IL-6 and adiponectin secretion in human adipocytes.

Al-Anazi A, Parhar R, Saleh S, Al-Hijailan R, Inglis A, Al-Jufan M, Bazzi M, Hashmi S, Conca W, Collison K, Al-Mohanna F.

Life Sci. 2018 Nov 1;212:275-284. doi: 10.1016/j.lfs.2018.10.014. Epub 2018 Oct 8.

9.

Effect of developmental NMDAR antagonism with CGP 39551 on aspartame-induced hypothalamic and adrenal gene expression.

Collison KS, Inglis A, Shibin S, Saleh S, Andres B, Ubungen R, Thiam J, Mata P, Al-Mohanna FA.

PLoS One. 2018 Mar 21;13(3):e0194416. doi: 10.1371/journal.pone.0194416. eCollection 2018.

10.

The DNA methyl-transferase protein DNMT1 enhances tumor-promoting properties of breast stromal fibroblasts.

Al-Kharashi LA, Al-Mohanna FH, Tulbah A, Aboussekhra A.

Oncotarget. 2017 Dec 18;9(2):2329-2343. doi: 10.18632/oncotarget.23411. eCollection 2018 Jan 5.

11.

A null mutation in MICU2 causes abnormal mitochondrial calcium homeostasis and a severe neurodevelopmental disorder.

Shamseldin HE, Alasmari A, Salih MA, Samman MM, Mian SA, Alshidi T, Ibrahim N, Hashem M, Faqeih E, Al-Mohanna F, Alkuraya FS.

Brain. 2017 Nov 1;140(11):2806-2813. doi: 10.1093/brain/awx237.

PMID:
29053821
12.

Obesity and p16INK4A Downregulation Activate Breast Adipocytes and Promote Their Protumorigenicity.

Al-Khalaf HH, Amir M, Al-Mohanna F, Tulbah A, Al-Sayed A, Aboussekhra A.

Mol Cell Biol. 2017 Aug 11;37(17). pii: e00101-17. doi: 10.1128/MCB.00101-17. Print 2017 Sep 1.

13.

PD-L1 promotes OCT4 and Nanog expression in breast cancer stem cells by sustaining PI3K/AKT pathway activation.

Almozyan S, Colak D, Mansour F, Alaiya A, Al-Harazi O, Qattan A, Al-Mohanna F, Al-Alwan M, Ghebeh H.

Int J Cancer. 2017 Oct 1;141(7):1402-1412. doi: 10.1002/ijc.30834. Epub 2017 Jun 30.

14.

Defective lipid metabolism associated with mutation in klf-2 and klf-3: important roles of essential dietary salts in fat storage.

Ling J, Brey C, Schilling M, Lateef F, Lopez-Dee ZP, Fernandes K, Thiruchelvam K, Wang Y, Chandel K, Rau K, Parhar R, Al-Mohanna F, Gaugler R, Hashmi S.

Nutr Metab (Lond). 2017 Feb 28;14:22. doi: 10.1186/s12986-017-0172-8. eCollection 2017.

15.

Cyp24a1 Attenuation Limits Progression of BrafV600E -Induced Papillary Thyroid Cancer Cells and Sensitizes Them to BRAFV600E Inhibitor PLX4720.

Zou M, Baitei EY, BinEssa HA, Al-Mohanna FA, Parhar RS, St-Arnaud R, Kimura S, Pritchard C, Alzahrani AS, Assiri AM, Meyer BF, Shi Y.

Cancer Res. 2017 Apr 15;77(8):2161-2172. doi: 10.1158/0008-5472.CAN-16-2066. Epub 2017 Feb 27.

16.

FOXP3+ regulatory T cell ameliorates microvasculature in the rejection of mouse orthotopic tracheal transplants.

Khan MA, Alanazi F, Ahmed HA, Al-Mohanna FH, Assiri AM, Broering DC.

Clin Immunol. 2017 Jan;174:84-98. doi: 10.1016/j.clim.2016.11.011. Epub 2016 Dec 9.

PMID:
27939405
17.

Differential effects of early-life NMDA receptor antagonism on aspartame-impaired insulin tolerance and behavior.

Collison KS, Inglis A, Shibin S, Andres B, Ubungen R, Thiam J, Mata P, Al-Mohanna FA.

Physiol Behav. 2016 Dec 1;167:209-221. doi: 10.1016/j.physbeh.2016.09.011. Epub 2016 Sep 15.

PMID:
27640132
18.

Fascin Is Critical for the Maintenance of Breast Cancer Stem Cell Pool Predominantly via the Activation of the Notch Self-Renewal Pathway.

Barnawi R, Al-Khaldi S, Majed Sleiman G, Sarkar A, Al-Dhfyan A, Al-Mohanna F, Ghebeh H, Al-Alwan M.

Stem Cells. 2016 Dec;34(12):2799-2813. doi: 10.1002/stem.2473. Epub 2016 Aug 21.

19.

Effect of aliskiren and carvedilol on expression of Ca(2+)/calmodulin-dependent protein kinase II δ-subunit isoforms in cardiac hypertrophy rat model.

Bin-Dayel AF, Abdel Baky NA, Fadda LM, Mohammad RA, Al-Mohanna F.

Toxicol Mech Methods. 2016 Feb;26(2):122-31. doi: 10.3109/15376516.2015.1128035. Epub 2016 Mar 16.

PMID:
26982530
20.

Target β-catenin/CD44/Nanog axis in colon cancer cells by certain N'-(2-oxoindolin-3-ylidene)-2-(benzyloxy)benzohydrazides.

Radwan AA, Al-Mohanna F, Alanazi FK, Manogaran PS, Al-Dhfyan A.

Bioorg Med Chem Lett. 2016 Apr 1;26(7):1664-70. doi: 10.1016/j.bmcl.2016.02.064. Epub 2016 Feb 23.

PMID:
26944615
21.

IL-12 immunotherapy of Braf(V600E)-induced papillary thyroid cancer in a mouse model.

Parhar RS, Zou M, Al-Mohanna FA, Baitei EY, Assiri AM, Meyer BF, Shi Y.

Lab Invest. 2016 Jan;96(1):89-97. doi: 10.1038/labinvest.2015.126. Epub 2015 Oct 26.

22.

TSH overcomes Braf(V600E)-induced senescence to promote tumor progression via downregulation of p53 expression in papillary thyroid cancer.

Zou M, Baitei EY, Al-Rijjal RA, Parhar RS, Al-Mohanna FA, Kimura S, Pritchard C, Binessa HA, Alzahrani AS, Al-Khalaf HH, Hawwari A, Akhtar M, Assiri AM, Meyer BF, Shi Y.

Oncogene. 2016 Apr 14;35(15):1909-18. doi: 10.1038/onc.2015.253. Epub 2015 Oct 19.

23.

Deletion of low molecular weight protein tyrosine phosphatase (Acp1) protects against stress-induced cardiomyopathy.

Wade F, Quijada P, Al-Haffar KM, Awad SM, Kunhi M, Toko H, Marashly Q, Belhaj K, Zahid I, Al-Mohanna F, Stanford SM, Alvarez R, Liu Y, Colak D, Jordan MC, Roos KP, Assiri A, Al-Habeeb W, Sussman M, Bottini N, Poizat C.

J Pathol. 2015 Dec;237(4):482-94. doi: 10.1002/path.4594. Epub 2015 Sep 1.

24.

KRAS(G12D)-mediated oncogenic transformation of thyroid follicular cells requires long-term TSH stimulation and is regulated by SPRY1.

Zou M, Baitei EY, Al-Rijjal RA, Parhar RS, Al-Mohanna FA, Kimura S, Pritchard C, BinEssa H, Alanazi AA, Alzahrani AS, Akhtar M, Assiri AM, Meyer BF, Shi Y.

Lab Invest. 2015 Nov;95(11):1269-77. doi: 10.1038/labinvest.2015.90. Epub 2015 Jul 6.

25.

Progression of matrixin and cardiokine expression patterns in an ovine model of heart failure and recovery.

Quttainah M, Al-Hejailan R, Saleh S, Parhar R, Conca W, Bulwer B, Moorjani N, Catarino P, Elsayed R, Shoukri M, AlJufan M, AlShahid M, Ouban A, Al-Halees Z, Westaby S, Collison K, Al-Mohanna F.

Int J Cardiol. 2015;186:77-89. doi: 10.1016/j.ijcard.2015.03.156. Epub 2015 Mar 17.

PMID:
25814349
26.

ISCA2 mutation causes infantile neurodegenerative mitochondrial disorder.

Al-Hassnan ZN, Al-Dosary M, Alfadhel M, Faqeih EA, Alsagob M, Kenana R, Almass R, Al-Harazi OS, Al-Hindi H, Malibari OI, Almutari FB, Tulbah S, Alhadeq F, Al-Sheddi T, Alamro R, AlAsmari A, Almuntashri M, Alshaalan H, Al-Mohanna FA, Colak D, Kaya N.

J Med Genet. 2015 Mar;52(3):186-94. doi: 10.1136/jmedgenet-2014-102592. Epub 2014 Dec 24.

PMID:
25539947
27.

Human cancer: is it linked to dysfunctional lipid metabolism?

Hashmi S, Wang Y, Suman DS, Parhar RS, Collison K, Conca W, Al-Mohanna F, Gaugler R.

Biochim Biophys Acta. 2015 Feb;1850(2):352-64. doi: 10.1016/j.bbagen.2014.11.004. Epub 2014 Nov 12. Review.

PMID:
25450488
28.

Association of a mutation in LACC1 with a monogenic form of systemic juvenile idiopathic arthritis.

Wakil SM, Monies DM, Abouelhoda M, Al-Tassan N, Al-Dusery H, Naim EA, Al-Younes B, Shinwari J, Al-Mohanna FA, Meyer BF, Al-Mayouf S.

Arthritis Rheumatol. 2015 Jan;67(1):288-95. doi: 10.1002/art.38877.

29.

Fascin is involved in the chemotherapeutic resistance of breast cancer cells predominantly via the PI3K/Akt pathway.

Ghebeh H, Al-Khaldi S, Olabi S, Al-Dhfyan A, Al-Mohanna F, Barnawi R, Tulbah A, Al-Tweigeri T, Ajarim D, Al-Alwan M.

Br J Cancer. 2014 Oct 14;111(8):1552-61. doi: 10.1038/bjc.2014.453. Epub 2014 Aug 12.

30.

Nuclear factor kappa-B signaling is integral to ocular neovascularization in ischemia-independent microenvironment.

DeNiro M, Al-Mohanna FA.

PLoS One. 2014 Jul 22;9(7):e101602. doi: 10.1371/journal.pone.0101602. eCollection 2014.

31.

Metformin in peritoneal dialysis: a pilot experience.

Al-Hwiesh AK, Abdul-Rahman IS, El-Deen MA, Larbi E, Divino-Filho JC, Al-Mohanna FA, Gupta KL.

Perit Dial Int. 2014 Jun;34(4):368-75. doi: 10.3747/pdi.2013.00048. Epub 2014 Mar 1.

32.

Increased CYP24A1 expression is associated with BRAF(V600E) mutation and advanced stages in papillary thyroid carcinoma.

Zou M, BinHumaid FS, Alzahrani AS, Baitei EY, Al-Mohanna FA, Meyer BF, Shi Y.

Clin Endocrinol (Oxf). 2014 Jul;81(1):109-16. doi: 10.1111/cen.12396. Epub 2014 Jan 21.

PMID:
24382015
33.

Breast stromal fibroblasts from histologically normal surgical margins are pro-carcinogenic.

Al-Rakan MA, Colak D, Hendrayani SF, Al-Bakheet A, Al-Mohanna FH, Kaya N, Al-Malik O, Aboussekhra A.

J Pathol. 2013 Dec;231(4):457-65. doi: 10.1002/path.4256.

34.

Identification of the tetraspanin CD82 as a new barrier to xenotransplantation.

Saleh SM, Parhar RS, Al-Hejailan RS, Bakheet RH, Khaleel HS, Khalak HG, Halees AS, Zaidi MZ, Meyer BF, Yung GP, Seebach JD, Conca W, Khabar KS, Collison KS, Al-Mohanna FA.

J Immunol. 2013 Sep 1;191(5):2796-805. doi: 10.4049/jimmunol.1300601. Epub 2013 Jul 19.

35.

Prediabetic changes in gene expression induced by aspartame and monosodium glutamate in Trans fat-fed C57Bl/6 J mice.

Collison KS, Makhoul NJ, Zaidi MZ, Inglis A, Andres BL, Ubungen R, Saleh S, Al-Mohanna FA.

Nutr Metab (Lond). 2013 Jun 19;10:44. doi: 10.1186/1743-7075-10-44. eCollection 2013.

36.

Profiling of normal and malignant breast tissue show CD44high/CD24low phenotype as a predominant stem/progenitor marker when used in combination with Ep-CAM/CD49f markers.

Ghebeh H, Sleiman GM, Manogaran PS, Al-Mazrou A, Barhoush E, Al-Mohanna FH, Tulbah A, Al-Faqeeh K, Adra CN.

BMC Cancer. 2013 Jun 14;13:289. doi: 10.1186/1471-2407-13-289.

37.

Regulation of lipoprotein assembly, secretion and fatty acid β-oxidation by Krüppel-like transcription factor, klf-3.

Zhang J, Hashmi S, Cheema F, Al-Nasser N, Bakheet R, Parhar RS, Al-Mohanna F, Gaugler R, Hussain MM, Hashmi S.

J Mol Biol. 2013 Aug 9;425(15):2641-55. doi: 10.1016/j.jmb.2013.04.020. Epub 2013 Apr 29.

38.

A C. elegans model to study human metabolic regulation.

Hashmi S, Wang Y, Parhar RS, Collison KS, Conca W, Al-Mohanna F, Gaugler R.

Nutr Metab (Lond). 2013 Apr 4;10(1):31. doi: 10.1186/1743-7075-10-31.

39.

The nexus between VEGF and NFκB orchestrates a hypoxia-independent neovasculogenesis.

DeNiro M, Al-Mohanna FH, Alsmadi O, Al-Mohanna FA.

PLoS One. 2013;8(3):e59021. doi: 10.1371/journal.pone.0059021. Epub 2013 Mar 22.

40.

Letter-to-the-Editor on "No effects of monosodium glutamate consumption on the body weight or composition of adult rats and mice"--further information.

Collison KS, Zaidi MZ, Inglis A, Al-Mohanna FA.

Physiol Behav. 2013 Feb 17;110-111:1-2. doi: 10.1016/j.physbeh.2012.11.010. Epub 2012 Dec 8. No abstract available.

PMID:
23231849
41.

Zinc transporter 8 (ZnT8) expression is reduced by ischemic insults: a potential therapeutic target to prevent ischemic retinopathy.

Deniro M, Al-Mohanna FA.

PLoS One. 2012;7(11):e50360. doi: 10.1371/journal.pone.0050360. Epub 2012 Nov 27.

42.

Loss of ERLIN2 function leads to juvenile primary lateral sclerosis.

Al-Saif A, Bohlega S, Al-Mohanna F.

Ann Neurol. 2012 Oct;72(4):510-6. doi: 10.1002/ana.23641.

PMID:
23109145
43.

POC1A truncation mutation causes a ciliopathy in humans characterized by primordial dwarfism.

Shaheen R, Faqeih E, Shamseldin HE, Noche RR, Sunker A, Alshammari MJ, Al-Sheddi T, Adly N, Al-Dosari MS, Megason SG, Al-Husain M, Al-Mohanna F, Alkuraya FS.

Am J Hum Genet. 2012 Aug 10;91(2):330-6. doi: 10.1016/j.ajhg.2012.05.025. Epub 2012 Jul 26.

44.

Interactive effects of neonatal exposure to monosodium glutamate and aspartame on glucose homeostasis.

Collison KS, Makhoul NJ, Zaidi MZ, Al-Rabiah R, Inglis A, Andres BL, Ubungen R, Shoukri M, Al-Mohanna FA.

Nutr Metab (Lond). 2012 Jun 14;9(1):58. doi: 10.1186/1743-7075-9-58.

45.

Partner in fat metabolism: role of KLFs in fat burning and reproductive behavior.

Hashmi S, Zhang J, Siddiqui SS, Parhar RS, Bakheet R, Al-Mohanna F.

3 Biotech. 2011 Sep;1(2):59-72. Epub 2011 Jul 16.

46.

Gender dimorphism in aspartame-induced impairment of spatial cognition and insulin sensitivity.

Collison KS, Makhoul NJ, Zaidi MZ, Saleh SM, Andres B, Inglis A, Al-Rabiah R, Al-Mohanna FA.

PLoS One. 2012;7(4):e31570. doi: 10.1371/journal.pone.0031570. Epub 2012 Apr 3.

47.

Induction of cell proliferation in old rat liver can reset certain gene expression levels characteristic of old liver to those associated with young liver.

Chishti MA, Kaya N, Binbakheet AB, Al-Mohanna F, Goyns MH, Colak D.

Age (Dordr). 2013 Jun;35(3):719-32. doi: 10.1007/s11357-012-9404-z. Epub 2012 Apr 4.

48.

Erythropoietin and anemia: biological markers that cannot be ignored in diabetic retinopathy.

DeNiro M, Al-Mohanna FA.

Med Hypotheses. 2012 Apr;78(4):555-6. doi: 10.1016/j.mehy.2012.01.026. Epub 2012 Feb 14. No abstract available.

PMID:
22336090
49.

Nutrigenomics of hepatic steatosis in a feline model: effect of monosodium glutamate, fructose, and Trans-fat feeding.

Collison KS, Zaidi MZ, Saleh SM, Makhoul NJ, Inglis A, Burrows J, Araujo JA, Al-Mohanna FA.

Genes Nutr. 2012 Apr;7(2):265-80. doi: 10.1007/s12263-011-0261-7. Epub 2011 Dec 6.

50.

Tissue factor/factor VIIa pathway mediates coagulation activation in induced-heat stroke in the baboon.

Bouchama A, Al-Mohanna F, Assad L, Baturcam E, Eldali A, Owaidah T, Dehbi M.

Crit Care Med. 2012 Apr;40(4):1229-36. doi: 10.1097/CCM.0b013e3182387bef.

PMID:
22080642

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