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Items: 8

1.

Quantitative Proteomics of Clinically Relevant Drug-Metabolizing Enzymes and Drug Transporters and Their Intercorrelations in the Human Small Intestine.

Couto N, Al-Majdoub ZM, Gibson S, Davies PJ, Achour B, Harwood MD, Carlson G, Barber J, Rostami-Hodjegan A, Warhurst G.

Drug Metab Dispos. 2020 Apr;48(4):245-254. doi: 10.1124/dmd.119.089656. Epub 2020 Jan 20.

PMID:
31959703
2.

Quantitative mass spectrometry-based proteomics in the era of model-informed drug development: Applications in translational pharmacology and recommendations for best practice.

El-Khateeb E, Vasilogianni AM, Alrubia S, Al-Majdoub ZM, Couto N, Howard M, Barber J, Rostami-Hodjegan A, Achour B.

Pharmacol Ther. 2019 Nov;203:107397. doi: 10.1016/j.pharmthera.2019.107397. Epub 2019 Jul 31. Review.

PMID:
31376433
3.

Proteomic Quantification of Human Blood-Brain Barrier SLC and ABC Transporters in Healthy Individuals and Dementia Patients.

Al-Majdoub ZM, Al Feteisi H, Achour B, Warwood S, Neuhoff S, Rostami-Hodjegan A, Barber J.

Mol Pharm. 2019 Mar 4;16(3):1220-1233. doi: 10.1021/acs.molpharmaceut.8b01189. Epub 2019 Feb 8.

PMID:
30735053
4.

Quantification of Proteins Involved in Drug Metabolism and Disposition in the Human Liver Using Label-Free Global Proteomics.

Couto N, Al-Majdoub ZM, Achour B, Wright PC, Rostami-Hodjegan A, Barber J.

Mol Pharm. 2019 Feb 4;16(2):632-647. doi: 10.1021/acs.molpharmaceut.8b00941. Epub 2019 Jan 18.

PMID:
30608694
5.

Identification and quantification of blood-brain barrier transporters in isolated rat brain microvessels.

Al Feteisi H, Al-Majdoub ZM, Achour B, Couto N, Rostami-Hodjegan A, Barber J.

J Neurochem. 2018 Sep;146(6):670-685. doi: 10.1111/jnc.14446. Epub 2018 Aug 1.

6.

Data Generated by Quantitative Liquid Chromatography-Mass Spectrometry Proteomics Are Only the Start and Not the Endpoint: Optimization of Quantitative Concatemer-Based Measurement of Hepatic Uridine-5'-Diphosphate-Glucuronosyltransferase Enzymes with Reference to Catalytic Activity.

Achour B, Dantonio A, Niosi M, Novak JJ, Al-Majdoub ZM, Goosen TC, Rostami-Hodjegan A, Barber J.

Drug Metab Dispos. 2018 Jun;46(6):805-812. doi: 10.1124/dmd.117.079475. Epub 2018 Mar 26.

PMID:
29581103
7.

Quantification of the proteins of the bacterial ribosome using QconCAT technology.

Al-Majdoub ZM, Carroll KM, Gaskell SJ, Barber J.

J Proteome Res. 2014 Mar 7;13(3):1211-22. doi: 10.1021/pr400667h. Epub 2014 Feb 12.

PMID:
24494973
8.

Effects of gentamicin on the proteomes of aerobic and oxygen-limited Escherichia coli.

Al-Majdoub ZM, Owoseni A, Gaskell SJ, Barber J.

J Med Chem. 2013 Apr 11;56(7):2904-10. doi: 10.1021/jm301858u. Epub 2013 Mar 29.

PMID:
23517076

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