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Synthesis of novel (R)-4-fluorophenyl-1H-1,2,3-triazoles: A new class of α-glucosidase inhibitors.

Avula SK, Khan A, Halim SA, Al-Abri Z, Anwar MU, Al-Rawahi A, Csuk R, Al-Harrasi A.

Bioorg Chem. 2019 Aug 2;91:103182. doi: 10.1016/j.bioorg.2019.103182. [Epub ahead of print]


The molecular mass and isoelectric point of plant proteomes.

Mohanta TK, Khan A, Hashem A, Abd Allah EF, Al-Harrasi A.

BMC Genomics. 2019 Aug 5;20(1):631. doi: 10.1186/s12864-019-5983-8.


N-substituted noscapine derivatives as new antiprotozoal agents: Synthesis, antiparasitic activity and molecular docking study.

Babanezhad Harikandei K, Salehi P, Ebrahimi SN, Bararjanian M, Kaiser M, Khavasi HR, Al-Harrasi A.

Bioorg Chem. 2019 Jul 11;91:103116. doi: 10.1016/j.bioorg.2019.103116. [Epub ahead of print]


Ureidobenzenesulfonamides as efficient inhibitors of carbonic anhydrase II.

Serbian I, Schwarzenberger P, Loesche A, Hoenke S, Al-Harrasi A, Csuk R.

Bioorg Chem. 2019 Jul 17;91:103123. doi: 10.1016/j.bioorg.2019.103123. [Epub ahead of print]


2-O-(2-chlorobenzoyl) maslinic acid triggers apoptosis in A2780 human ovarian carcinoma cells.

Serbian I, Siewert B, Al-Harrasi A, Csuk R.

Eur J Med Chem. 2019 Jul 16;180:457-464. doi: 10.1016/j.ejmech.2019.07.049. [Epub ahead of print]


Complete chloroplast genomes of medicinally important Teucrium species and comparative analyses with related species from Lamiaceae.

Khan A, Asaf S, Khan AL, Khan A, Al-Harrasi A, Al-Sudairy O, AbdulKareem NM, Al-Saady N, Al-Rawahi A.

PeerJ. 2019 Jul 9;7:e7260. doi: 10.7717/peerj.7260. eCollection 2019.


Phytohormones enabled endophytic Penicillium funiculosum LHL06 protects Glycine max L. from synergistic toxicity of heavy metals by hormonal and stress-responsive proteins modulation.

Bilal S, Shahzad R, Khan AL, Al-Harrasi A, Kim CK, Lee IJ.

J Hazard Mater. 2019 Jun 25;379:120824. doi: 10.1016/j.jhazmat.2019.120824. [Epub ahead of print]


Secondary metabolites from the resins of Aloe vera and Commiphora mukul mitigate lipid peroxidation.

Rehman NU, Al-Riyami SA, Hussain H, Ali A, Khan AL, Al-Harrasi A.

Acta Pharm. 2019 Sep 1;69(3):433-441. doi: 10.2478/acph-2019-0027.


Rifampicin conjugated silver nanoparticles: a new arena for development of antibiofilm potential against methicillin resistant Staphylococcus aureus and Klebsiella pneumoniae.

Farooq U, Ahmad T, Khan A, Sarwar R, Shafiq J, Raza Y, Ahmed A, Ullah S, Ur Rehman N, Al-Harrasi A.

Int J Nanomedicine. 2019 May 29;14:3983-3993. doi: 10.2147/IJN.S198194. eCollection 2019.


Synthesis and Cytotoxicity Evaluation of DOTA-Conjugates of Ursolic Acid.

Kahnt M, Hoenke S, Fischer L, Al-Harrasi A, Csuk R.

Molecules. 2019 Jun 17;24(12). pii: E2254. doi: 10.3390/molecules24122254.


The cytotoxicity of oleanane derived aminocarboxamides depends on their aminoalkyl substituents.

Kahnt M, Loesche A, Serbian I, Hoenke S, Fischer L, Al-Harrasi A, Csuk R.

Steroids. 2019 Sep;149:108422. doi: 10.1016/j.steroids.2019.05.014. Epub 2019 Jun 6.


Natural urease inhibitors from Aloe vera resin and Lycium shawii and their structural-activity relationship and molecular docking study.

Rehman NU, Khan A, Al-Harrasi A, Khiat M, Hussain H, Wadood A, Riaz M.

Bioorg Chem. 2019 Jul;88:102955. doi: 10.1016/j.bioorg.2019.102955. Epub 2019 Apr 27.


Evidence for the involvement of a GABAergic mechanism in the effectiveness of natural and synthetically modified incensole derivatives in neuropharmacological disorders: A computational and pharmacological approach.

Al-Harrasi A, Khan A, Rehman NU, Al-Shidhani S, Karim N, Khan I, Halim SA, Al-Rawahi A, Hussain J, Csuk R.

Phytochemistry. 2019 Jul;163:58-74. doi: 10.1016/j.phytochem.2019.04.007. Epub 2019 Apr 20.


Anti-nociceptive and Anti-inflammatory Activities of Asparacosin A Involve Selective Cyclooxygenase 2 and Inflammatory Cytokines Inhibition: An in-vitro, in-vivo, and in-silico Approach.

Karim N, Khan I, Khan W, Khan I, Khan A, Halim SA, Khan H, Hussain J, Al-Harrasi A.

Front Immunol. 2019 Mar 26;10:581. doi: 10.3389/fimmu.2019.00581. eCollection 2019.


New derivatives of 11-keto-β-boswellic acid (KBA) induce apoptosis in breast and prostate cancers cells.

Bini Araba A, Ur Rehman N, Al-Araimi A, Al-Hashmi S, Al-Shidhani S, Csuk R, Hussain H, Al-Harrasi A, Zadjali F.

Nat Prod Res. 2019 Apr 1:1-10. doi: 10.1080/14786419.2019.1593165. [Epub ahead of print]


Molecular Players of EF-hand Containing Calcium Signaling Event in Plants.

Mohanta TK, Yadav D, Khan AL, Hashem A, Abd Allah EF, Al-Harrasi A.

Int J Mol Sci. 2019 Mar 23;20(6). pii: E1476. doi: 10.3390/ijms20061476. Review.


Synthesis and characterization of new thiosemicarbazones, as potent urease inhibitors: In vitro and in silico studies.

Islam M, Khan A, Shehzad MT, Hameed A, Ahmed N, Halim SA, Khiat M, Anwar MU, Hussain J, Csuk R, Shafiq Z, Al-Harrasi A.

Bioorg Chem. 2019 Jun;87:155-162. doi: 10.1016/j.bioorg.2019.03.008. Epub 2019 Mar 6.


Apoptotic and antimetastatic activities of betulin isolated from Quercus incana against non-small cell lung cancer cells.

Zehra B, Ahmed A, Sarwar R, Khan A, Farooq U, Abid Ali S, Al-Harrasi A.

Cancer Manag Res. 2019 Feb 19;11:1667-1683. doi: 10.2147/CMAR.S186956. eCollection 2019.


Identification and Characterization of the Caspase-Mediated Apoptotic Activity of Teucrium mascatense and an Isolated Compound in Human Cancer Cells.

Panicker NG, Balhamar SOMS, Akhlaq S, Qureshi MM, Rizvi TS, Al-Harrasi A, Hussain J, Mustafa F.

Molecules. 2019 Mar 11;24(5). pii: E977. doi: 10.3390/molecules24050977.


Crystal structure, shape analysis and bioactivity of new LiI, NaI and MgII complexes with 1,10-phenanthroline and 2-(3,4-dichlorophenyl)acetic acid.

Shah SR, Shah Z, Ullah N, Hussain J, Al-Harrasi R, Khan A, Rawson JM, Al-Harrasi A, Anwar MU.

Acta Crystallogr C Struct Chem. 2019 Mar 1;75(Pt 3):294-303. doi: 10.1107/S2053229619001396. Epub 2019 Feb 13.


Distribution of the anti-inflammatory and anti-depressant compounds: Incensole and incensole acetate in genus Boswellia.

Al-Harrasi A, Csuk R, Khan A, Hussain J.

Phytochemistry. 2019 May;161:28-40. doi: 10.1016/j.phytochem.2019.01.007. Epub 2019 Feb 22. Review.


The management of diabetes mellitus-imperative role of natural products against dipeptidyl peptidase-4, α-glucosidase and sodium-dependent glucose co-transporter 2 (SGLT2).

Abbas G, Al Harrasi A, Hussain H, Hamaed A, Supuran CT.

Bioorg Chem. 2019 May;86:305-315. doi: 10.1016/j.bioorg.2019.02.009. Epub 2019 Feb 4. Review.


Biotransformation of benzoin by Sphingomonas sp. LK11 and ameliorative effects on growth of Cucumis sativus.

Ali A, Mohanta TK, Asaf S, Rehman N, Al-Housni S, Al-Harrasi A, Khan AL, Al-Rawahi A.

Arch Microbiol. 2019 Jul;201(5):591-601. doi: 10.1007/s00203-019-01623-1. Epub 2019 Feb 4.


Synthesis of new boswellic acid derivatives as potential antiproliferative agents.

Shamraiz U, Hussain H, Ur Rehman N, Al-Shidhani S, Saeed A, Khan HY, Khan A, Fischer L, Csuk R, Badshah A, Al-Rawahi A, Hussain J, Al-Harrasi A.

Nat Prod Res. 2019 Jan 29:1-8. doi: 10.1080/14786419.2018.1564295. [Epub ahead of print]


Genomic and evolutionary aspects of chloroplast tRNA in monocot plants.

Mohanta TK, Khan AL, Hashem A, Allah EFA, Yadav D, Al-Harrasi A.

BMC Plant Biol. 2019 Jan 22;19(1):39. doi: 10.1186/s12870-018-1625-6.


First complete chloroplast genomics and comparative phylogenetic analysis of Commiphora gileadensis and C. foliacea: Myrrh producing trees.

Khan A, Asaf S, Khan AL, Al-Harrasi A, Al-Sudairy O, AbdulKareem NM, Khan A, Shehzad T, Alsaady N, Al-Lawati A, Al-Rawahi A, Shinwari ZK.

PLoS One. 2019 Jan 10;14(1):e0208511. doi: 10.1371/journal.pone.0208511. eCollection 2019.


Ursolic and oleanolic acid derivatives with cholinesterase inhibiting potential.

Loesche A, Köwitsch A, Lucas SD, Al-Halabi Z, Sippl W, Al-Harrasi A, Csuk R.

Bioorg Chem. 2019 Apr;85:23-32. doi: 10.1016/j.bioorg.2018.12.013. Epub 2018 Dec 15.


Endogenous phytohormones of frankincense producing Boswellia sacra tree populations.

Khan AL, Mabood F, Akber F, Ali A, Shahzad R, Al-Harrasi A, Al-Rawahi A, Shinwari ZK, Lee IJ.

PLoS One. 2018 Dec 19;13(12):e0207910. doi: 10.1371/journal.pone.0207910. eCollection 2018.


An Electrostatically Enhanced Phenol as a Simple and Efficient Bifunctional Organocatalyst for Carbon Dioxide Fixation.

Rostami A, Mahmoodabadi M, Hossein Ebrahimi A, Khosravi H, Al-Harrasi A.

ChemSusChem. 2018 Dec 20;11(24):4262-4268. doi: 10.1002/cssc.201802028. Epub 2018 Nov 26.


Ethylenediamine Derived Carboxamides of Betulinic and Ursolic Acid as Potential Cytotoxic Agents.

Kahnt M, Fischer Née Heller L, Al-Harrasi A, Csuk R.

Molecules. 2018 Oct 8;23(10). pii: E2558. doi: 10.3390/molecules23102558.


Endophytic Microbial Consortia of Phytohormones-Producing Fungus Paecilomyces formosus LHL10 and Bacteria Sphingomonas sp. LK11 to Glycine max L. Regulates Physio-hormonal Changes to Attenuate Aluminum and Zinc Stresses.

Bilal S, Shahzad R, Khan AL, Kang SM, Imran QM, Al-Harrasi A, Yun BW, Lee IJ.

Front Plant Sci. 2018 Sep 4;9:1273. doi: 10.3389/fpls.2018.01273. eCollection 2018.


Complete genome sequencing and analysis of endophytic Sphingomonas sp. LK11 and its potential in plant growth.

Asaf S, Khan AL, Khan MA, Al-Harrasi A, Lee IJ.

3 Biotech. 2018 Sep;8(9):389. doi: 10.1007/s13205-018-1403-z. Epub 2018 Aug 28.


Mechanisms of Cr(VI) resistance by endophytic Sphingomonas sp. LK11 and its Cr(VI) phytotoxic mitigating effects in soybean (Glycine max L.).

Bilal S, Khan AL, Shahzad R, Kim YH, Imran M, Khan MJ, Al-Harrasi A, Kim TH, Lee IJ.

Ecotoxicol Environ Saf. 2018 Nov 30;164:648-658. doi: 10.1016/j.ecoenv.2018.08.043. Epub 2018 Aug 28.


First reported chloroplast genome sequence of Punica granatum (cultivar Helow) from Jabal Al-Akhdar, Oman: phylogenetic comparative assortment with Lagerstroemia.

Khan AL, Asaf S, Lee IJ, Al-Harrasi A, Al-Rawahi A.

Genetica. 2018 Dec;146(6):461-474. doi: 10.1007/s10709-018-0037-8. Epub 2018 Aug 29.


Synthesis of 1H-1,2,3-triazole derivatives as new α-glucosidase inhibitors and their molecular docking studies.

Avula SK, Khan A, Rehman NU, Anwar MU, Al-Abri Z, Wadood A, Riaz M, Csuk R, Al-Harrasi A.

Bioorg Chem. 2018 Dec;81:98-106. doi: 10.1016/j.bioorg.2018.08.008. Epub 2018 Aug 7.


Anti-proliferative potential of cyclotetrapeptides from Bacillus velezensis RA5401 and their molecular docking on G-Protein-Coupled Receptors.

Rehman NU, Abed RMM, Hussain H, Khan HY, Khan A, Khan AL, Ali M, Al-Nasri A, Al-Harrasi K, Al-Rawahi AN, Wadood A, Al-Rawahi A, Al-Harrasi A.

Microb Pathog. 2018 Oct;123:419-425. doi: 10.1016/j.micpath.2018.07.043. Epub 2018 Jul 31.


First chloroplast genomics study of Phoenix dactylifera (var. Naghal and Khanezi): A comparative analysis.

Khan AL, Asaf S, Lee IJ, Al-Harrasi A, Al-Rawahi A.

PLoS One. 2018 Jul 31;13(7):e0200104. doi: 10.1371/journal.pone.0200104. eCollection 2018.


Synthesis, biological activities, and molecular docking studies of 2-mercaptobenzimidazole based derivatives.

Ali M, Ali S, Khan M, Rashid U, Ahmad M, Khan A, Al-Harrasi A, Ullah F, Latif A.

Bioorg Chem. 2018 Oct;80:472-479. doi: 10.1016/j.bioorg.2018.06.032. Epub 2018 Jun 30.


Homopiperazine-rhodamine B adducts of triterpenoic acids are strong mitocans.

Wolfram RK, Fischer L, Kluge R, Ströhl D, Al-Harrasi A, Csuk R.

Eur J Med Chem. 2018 Jul 15;155:869-879. doi: 10.1016/j.ejmech.2018.06.051. Epub 2018 Jun 27.


Chemical, molecular and structural studies of Boswellia species: β-Boswellic Aldehyde and 3-epi-11β-Dihydroxy BA as precursors in biosynthesis of boswellic acids.

Al-Harrasi A, Rehman NU, Khan AL, Al-Broumi M, Al-Amri I, Hussain J, Hussain H, Csuk R.

PLoS One. 2018 Jun 18;13(6):e0198666. doi: 10.1371/journal.pone.0198666. eCollection 2018.


Isolation and Characterization of Two New Secondary Metabolites From Quercus incana and Their Antidepressant- and Anxiolytic-Like Potential.

Sarwar R, Farooq U, Naz S, Khan A, Bukhari SM, Khan H, Karim N, Khan I, Ahmed A, Al-Harrasi A.

Front Pharmacol. 2018 Apr 18;9:298. doi: 10.3389/fphar.2018.00298. eCollection 2018.


New α-Glucosidase inhibitors from the resins of Boswellia species with structure-glucosidase activity and molecular docking studies.

Ur Rehman N, Khan A, Al-Harrasi A, Hussain H, Wadood A, Riaz M, Al-Abri Z.

Bioorg Chem. 2018 Sep;79:27-33. doi: 10.1016/j.bioorg.2018.04.020. Epub 2018 Apr 25.


In vitro oxidative stress regulatory potential of Citrullus colocynthis and Tephrosia apollinea.

Rizvi TS, Khan AL, Ali L, Al-Mawali N, Mabood F, Hussain J, Adnan M, Al-Harrasi A.

Acta Pharm. 2018 Jun 1;68(2):235-242. doi: 10.2478/acph-2018-0012.


Applications of FT-NIRS combined with PLS multivariate methods for the detection & quantification of saccharin adulteration in commercial fruit juices.

Mabood F, Hussain J, Jabeen F, Abbas G, Allaham B, Albroumi M, Alghawi S, Alameri S, Gilani SA, Al-Harrasi A, Haq QMI, Farooq S.

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2018 Jun;35(6):1052-1060. doi: 10.1080/19440049.2018.1457802. Epub 2018 Jun 18.


Combined in Vitro and in Silico Studies for the Anticholinesterase Activity and Pharmacokinetics of Coumarinyl Thiazoles and Oxadiazoles.

Ibrar A, Khan A, Ali M, Sarwar R, Mehsud S, Farooq U, Halimi SMA, Khan I, Al-Harrasi A.

Front Chem. 2018 Mar 26;6:61. doi: 10.3389/fchem.2018.00061. eCollection 2018.


Therapeutic applications of bacterial pigments: a review of current status and future opportunities.

Numan M, Bashir S, Mumtaz R, Tayyab S, Rehman NU, Khan AL, Shinwari ZK, Al-Harrasi A.

3 Biotech. 2018 Apr;8(4):207. doi: 10.1007/s13205-018-1227-x. Epub 2018 Apr 4. Review.


Effect of phosphate nutrition on growth, physiology and phosphate transporter expression of cucumber seedlings.

Naureen Z, Sham A, Al Ashram H, Gilani SA, Al Gheilani S, Mabood F, Hussain J, Al Harrasi A, AbuQamar SF.

Plant Physiol Biochem. 2018 Jun;127:211-222. doi: 10.1016/j.plaphy.2018.03.028. Epub 2018 Mar 26.


Complete chloroplast genome sequence and comparative analysis of loblolly pine (Pinus taeda L.) with related species.

Asaf S, Khan AL, Khan MA, Shahzad R, Lubna, Kang SM, Al-Harrasi A, Al-Rawahi A, Lee IJ.

PLoS One. 2018 Mar 29;13(3):e0192966. doi: 10.1371/journal.pone.0192966. eCollection 2018.


Plant growth promoting bacteria as an alternative strategy for salt tolerance in plants: A review.

Numan M, Bashir S, Khan Y, Mumtaz R, Shinwari ZK, Khan AL, Khan A, Al-Harrasi A.

Microbiol Res. 2018 Apr;209:21-32. doi: 10.1016/j.micres.2018.02.003. Epub 2018 Feb 13. Review.


Application of reflectance spectroscopies (FTIR-ATR & FT-NIR) coupled with multivariate methods for robust in vivo detection of begomovirus infection in papaya leaves.

Haq QMI, Mabood F, Naureen Z, Al-Harrasi A, Gilani SA, Hussain J, Jabeen F, Khan A, Al-Sabari RSM, Al-Khanbashi FHS, Al-Fahdi AAM, Al-Zaabi AKA, Al-Shuraiqi FAM, Al-Bahaisi IM.

Spectrochim Acta A Mol Biomol Spectrosc. 2018 Jun 5;198:27-32. doi: 10.1016/j.saa.2018.02.065. Epub 2018 Feb 27.


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