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Items: 44

1.

Targeting Filamin A Reduces Macrophage Activity and Atherosclerosis.

Bandaru S, Ala C, Salimi R, Akula MK, Ekstrand M, Devarakonda S, Karlsson J, Van den Eynden J, Bergström G, Larsson E, Levin M, Borén J, Bergo MO, Akyürek LM.

Circulation. 2019 Jul 2;140(1):67-79. doi: 10.1161/CIRCULATIONAHA.119.039697. Epub 2019 Apr 24.

PMID:
31014088
2.

Blocking the Cleavage of Filamin A by Calpain Inhibitor Decreases Tumor Cell Growth.

Salimi R, Bandaru S, Devarakonda S, Gökalp S, Ala C, Alvandian A, Yener N, Akyürek LM.

Anticancer Res. 2018 Apr;38(4):2079-2085.

PMID:
29599325
3.

Sense-Antisense lncRNA Pair Encoded by Locus 6p22.3 Determines Neuroblastoma Susceptibility via the USP36-CHD7-SOX9 Regulatory Axis.

Mondal T, Juvvuna PK, Kirkeby A, Mitra S, Kosalai ST, Traxler L, Hertwig F, Wernig-Zorc S, Miranda C, Deland L, Volland R, Bartenhagen C, Bartsch D, Bandaru S, Engesser A, Subhash S, Martinsson T, Carén H, Akyürek LM, Kurian L, Kanduri M, Huarte M, Kogner P, Fischer M, Kanduri C.

Cancer Cell. 2018 Mar 12;33(3):417-434.e7. doi: 10.1016/j.ccell.2018.01.020.

4.

Spontaneous twin pregnancy with live births after cryopreservation and re-implantation of ovarian tissue.

Milenkovic M, Brännström M, Diaz-Garcia C, Lundin K, Selleskog U, Söderlund B, Khatibi A, Gull B, Bokström H, Mateoiu C, Akyürek LM, Thurin-Kjellberg A.

Gynecol Surg. 2017;14(1):9. doi: 10.1186/s10397-017-1012-6. Epub 2017 Jun 14. No abstract available.

5.

Depletion of ATP and glucose in advanced human atherosclerotic plaques.

Ekstrand M, Widell E, Hammar A, Akyürek LM, Johansson M, Fagerberg B, Bergström G, Levin MC, Fogelstrand P, Borén J, Levin M.

PLoS One. 2017 Jun 1;12(6):e0178877. doi: 10.1371/journal.pone.0178877. eCollection 2017.

6.

Antioxidants can increase melanoma metastasis in mice.

Le Gal K, Ibrahim MX, Wiel C, Sayin VI, Akula MK, Karlsson C, Dalin MG, Akyürek LM, Lindahl P, Nilsson J, Bergo MO.

Sci Transl Med. 2015 Oct 7;7(308):308re8. doi: 10.1126/scitranslmed.aad3740.

PMID:
26446958
7.

p110α Hot Spot Mutations E545K and H1047R Exert Metabolic Reprogramming Independently of p110α Kinase Activity.

Chaudhari A, Krumlinde D, Lundqvist A, Akyürek LM, Bandaru S, Skålén K, Ståhlman M, Borén J, Wettergren Y, Ejeskär K, Rotter Sopasakis V.

Mol Cell Biol. 2015 Oct;35(19):3258-73. doi: 10.1128/MCB.00471-15. Epub 2015 Jul 13.

8.

[Research assistant program attracts research interested in Gothenburg].

Akyürek LM, Hessulf F, Tang KW, Hanse E, Lindholm C.

Lakartidningen. 2014 Dec 2;111(49-50):2237. Swedish. No abstract available.

9.

The risk-associated long noncoding RNA NBAT-1 controls neuroblastoma progression by regulating cell proliferation and neuronal differentiation.

Pandey GK, Mitra S, Subhash S, Hertwig F, Kanduri M, Mishra K, Fransson S, Ganeshram A, Mondal T, Bandaru S, Ostensson M, Akyürek LM, Abrahamsson J, Pfeifer S, Larsson E, Shi L, Peng Z, Fischer M, Martinsson T, Hedborg F, Kogner P, Kanduri C.

Cancer Cell. 2014 Nov 10;26(5):722-37. doi: 10.1016/j.ccell.2014.09.014. Epub 2014 Nov 10.

10.

Deficiency of filamin A in endothelial cells impairs left ventricular remodelling after myocardial infarction.

Bandaru S, Grönros J, Redfors B, Çil Ç, Pazooki D, Salimi R, Larsson E, Zhou AX, Ömerovic E, Akyürek LM.

Cardiovasc Res. 2015 Feb 1;105(2):151-9. doi: 10.1093/cvr/cvu226. Epub 2014 Oct 24.

PMID:
25344364
11.

Targeting filamin B induces tumor growth and metastasis via enhanced activity of matrix metalloproteinase-9 and secretion of VEGF-A.

Bandaru S, Zhou AX, Rouhi P, Zhang Y, Bergo MO, Cao Y, Akyürek LM.

Oncogenesis. 2014 Sep 22;3:e119. doi: 10.1038/oncsis.2014.33.

12.

Hypoxia-induced and calpain-dependent cleavage of filamin A regulates the hypoxic response.

Zheng X, Zhou AX, Rouhi P, Uramoto H, Borén J, Cao Y, Pereira T, Akyürek LM, Poellinger L.

Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2560-5. doi: 10.1073/pnas.1320815111. Epub 2014 Feb 3.

13.

Targeting filamin A reduces K-RAS-induced lung adenocarcinomas and endothelial response to tumor growth in mice.

Nallapalli RK, Ibrahim MX, Zhou AX, Bandaru S, Sunkara SN, Redfors B, Pazooki D, Zhang Y, Borén J, Cao Y, Bergo MO, Akyürek LM.

Mol Cancer. 2012 Aug 2;11:50. doi: 10.1186/1476-4598-11-50.

14.

Dose-dependent cardioprotection of enkephalin analogue Eribis peptide 94 and cardiac expression of opioid receptors in a porcine model of ischaemia and reperfusion.

Karlsson LO, Bergh N, Li L, Bissessar E, Bobrova I, Gross GJ, Akyürek LM, Grip L.

Eur J Pharmacol. 2012 Jan 15;674(2-3):378-83. doi: 10.1016/j.ejphar.2011.11.012. Epub 2011 Nov 16.

PMID:
22119384
15.

A positive relationship between filamin and VEGF in patients with lung cancer.

Uramoto H, Akyürek LM, Hanagiri T.

Anticancer Res. 2010 Oct;30(10):3939-44.

PMID:
21036706
16.

Filamin a mediates HGF/c-MET signaling in tumor cell migration.

Zhou AX, Toylu A, Nallapalli RK, Nilsson G, Atabey N, Heldin CH, Borén J, Bergo MO, Akyürek LM.

Int J Cancer. 2011 Feb 15;128(4):839-46. doi: 10.1002/ijc.25417.

17.

Cyclosporine does not reduce myocardial infarct size in a porcine ischemia-reperfusion model.

Karlsson LO, Zhou AX, Larsson E, Aström-Olsson K, Månsson C, Akyürek LM, Grip L.

J Cardiovasc Pharmacol Ther. 2010 Jun;15(2):182-9. doi: 10.1177/1074248410362074.

PMID:
20435992
18.

Deficiency of cyclin-dependent kinase inhibitors p21Cip1 and p27Kip1 accelerates atherogenesis in apolipoprotein E-deficient mice.

Akyürek LM, Boehm M, Olive M, Zhou AX, San H, Nabel EG.

Biochem Biophys Res Commun. 2010 May 28;396(2):359-63. doi: 10.1016/j.bbrc.2010.04.097. Epub 2010 Apr 24.

19.

Filamins in cell signaling, transcription and organ development.

Zhou AX, Hartwig JH, Akyürek LM.

Trends Cell Biol. 2010 Feb;20(2):113-23. doi: 10.1016/j.tcb.2009.12.001. Epub 2010 Jan 12. Review.

PMID:
20061151
20.

Endothelial cells are activated during hypoxia via endoglin/ALK-1/SMAD1/5 signaling in vivo and in vitro.

Tian F, Zhou AX, Smits AM, Larsson E, Goumans MJ, Heldin CH, Borén J, Akyürek LM.

Biochem Biophys Res Commun. 2010 Feb 12;392(3):283-8. doi: 10.1016/j.bbrc.2009.12.170. Epub 2010 Jan 10.

PMID:
20060813
21.

Differences in lesion severity and cellular composition between in vivo assessed upstream and downstream sides of human symptomatic carotid atherosclerotic plaques.

Fagerberg B, Ryndel M, Kjelldahl J, Akyürek LM, Rosengren L, Karlström L, Bergström G, Olson FJ.

J Vasc Res. 2010;47(3):221-30. doi: 10.1159/000255965. Epub 2009 Nov 6.

22.

Protein disulfide isomerase increases in myocardial endothelial cells in mice exposed to chronic hypoxia: a stimulatory role in angiogenesis.

Tian F, Zhou X, Wikström J, Karlsson H, Sjöland H, Gan LM, Borén J, Akyürek LM.

Am J Physiol Heart Circ Physiol. 2009 Sep;297(3):H1078-86. doi: 10.1152/ajpheart.00937.2008. Epub 2009 Jul 17.

23.

Gene transfer to arteries.

Akyürek LM, San H, Nabel EG, Singh R, Simari RD.

Curr Protoc Hum Genet. 2002 Feb;Chapter 13:Unit13.1. doi: 10.1002/0471142905.hg1301s31.

PMID:
18428325
24.

Developmental origin of smooth muscle cells in the descending aorta in mice.

Wasteson P, Johansson BR, Jukkola T, Breuer S, Akyürek LM, Partanen J, Lindahl P.

Development. 2008 May;135(10):1823-32. doi: 10.1242/dev.020958. Epub 2008 Apr 16.

25.

15-Lipoxygenase-2 expression in human macrophages induces chemokine secretion and T cell migration.

Danielsson KN, Rydberg EK, Ingelsten M, Akyürek LM, Jirholt P, Ullström C, Forsberg GB, Borén J, Wiklund O, Hultén LM.

Atherosclerosis. 2008 Jul;199(1):34-40. Epub 2007 Dec 11.

PMID:
18067895
26.

Filamins in cardiovascular development.

Zhou X, Borén J, Akyürek LM.

Trends Cardiovasc Med. 2007 Oct;17(7):222-9. Review.

PMID:
17936203
27.

Filamin B deficiency in mice results in skeletal malformations and impaired microvascular development.

Zhou X, Tian F, Sandzén J, Cao R, Flaberg E, Szekely L, Cao Y, Ohlsson C, Bergo MO, Borén J, Akyürek LM.

Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):3919-24. Epub 2007 Feb 26.

28.

RhoA-dependent vascular smooth muscle cell-specific transcription: adding diaphanous formins to the puzzle.

Larsson E, Zhou X, Akyürek LM.

Arterioscler Thromb Vasc Biol. 2007 Mar;27(3):448-9. No abstract available.

PMID:
17301322
29.

Diverse origin of vascular smooth muscle cells in the neointima.

Zhou X, Beck C, Boren J, Akyürek LM.

Anadolu Kardiyol Derg. 2005 Sep;5(3):216-20. Review. No abstract available.

30.

Tissue-specific targeting for cardiovascular gene transfer. Potential vectors and future challenges.

Beck C, Uramoto H, Borén J, Akyürek LM.

Curr Gene Ther. 2004 Dec;4(4):457-67. Review.

PMID:
15578994
31.

Enhanced mucosal immunoglobulin A response of intranasal adenoviral vector human immunodeficiency virus vaccine and localization in the central nervous system.

Lemiale F, Kong WP, Akyürek LM, Ling X, Huang Y, Chakrabarti BK, Eckhaus M, Nabel GJ.

J Virol. 2003 Sep;77(18):10078-87.

32.

Cell cycle signaling and cardiovascular disease.

Nabel EG, Boehm M, Akyurek LM, Yoshimoto T, Crook MF, Olive M, San H, Qu X.

Cold Spring Harb Symp Quant Biol. 2002;67:163-70. No abstract available.

PMID:
12858537
33.

Gene transfer strategies to inhibit neointima formation.

Crook MF, Akyürek LM.

Trends Cardiovasc Med. 2003 Apr;13(3):102-6. Review.

PMID:
12691673
34.
35.

SM22alpha promoter targets gene expression to vascular smooth muscle cells in vitro and in vivo.

Akyürek LM, Yang ZY, Aoki K, San H, Nabel GJ, Parmacek MS, Nabel EG.

Mol Med. 2000 Nov;6(11):983-91.

36.

Restricted expression of an adenoviral vector encoding Fas ligand (CD95L) enhances safety for cancer gene therapy.

Aoki K, Akyürek LM, San H, Leung K, Parmacek MS, Nabel EG, Nabel GJ.

Mol Ther. 2000 Jun;1(6):555-65.

37.

Differential effects of the cyclin-dependent kinase inhibitors p27(Kip1), p21(Cip1), and p16(Ink4) on vascular smooth muscle cell proliferation.

Tanner FC, Boehm M, Akyürek LM, San H, Yang ZY, Tashiro J, Nabel GJ, Nabel EG.

Circulation. 2000 May 2;101(17):2022-5.

PMID:
10790340
38.

Eotaxin and capping protein in experimental vasculopathy.

Chen J, Akyürek LM, Fellström B, Häyry P, Paul LC.

Am J Pathol. 1998 Jul;153(1):81-90.

39.

Tolerance induction ameliorates allograft vasculopathy in rat aortic transplants. Influence of Fas-mediated apoptosis.

Akyürek LM, Johnsson C, Lange D, Georgii-Hemming P, Larsson E, Fellström BC, Funa K, Tufveson G.

J Clin Invest. 1998 Jun 15;101(12):2889-99.

40.

Ischemia causes rapidly progressive nephropathy in the diabetic rat.

Melin J, Hellberg O, Akyürek LM, Källskog O, Larsson E, Fellström BC.

Kidney Int. 1997 Oct;52(4):985-91.

41.

Inducible and endothelial nitric oxide synthase expression during development of transplant arteriosclerosis in rat aortic grafts.

Akyürek LM, Fellström BC, Yan ZQ, Hansson GK, Funa K, Larsson E.

Am J Pathol. 1996 Dec;149(6):1981-90.

42.

Smooth muscle cell migration into intima and adventitia during development of transplant vasculopathy.

Akyürek LM, Paul LC, Funa K, Larsson E, Fellström BC.

Transplantation. 1996 Nov 27;62(10):1526-9.

PMID:
8958288
43.

Identification of differentially expressed genes in rat aortic allograft vasculopathy.

Chen J, Myllärniemi M, Akyürek LM, Häyry P, Marsden PA, Paul LC.

Am J Pathol. 1996 Aug;149(2):597-611.

44.

Inhibition of transplant arteriosclerosis in rat aortic grafts by low molecular weight heparin derivatives.

Akyürek LM, Funa K, Wanders A, Larsson E, Fellström BC.

Transplantation. 1995 Jun 15;59(11):1517-24.

PMID:
7778166

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