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Items: 1 to 50 of 128

1.

Multiple nuclear-replicating viruses require the stress-induced protein ZC3H11A for efficient growth.

Younis S, Kamel W, Falkeborn T, Wang H, Yu D, Daniels R, Essand M, Hinkula J, Akusjärvi G, Andersson L.

Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):E3808-E3816. doi: 10.1073/pnas.1722333115. Epub 2018 Apr 2.

2.

An Ago2-associated capped transcriptional start site small RNA suppresses adenovirus DNA replication.

Kamel W, Akusjärvi G.

RNA. 2017 Nov;23(11):1700-1711. doi: 10.1261/rna.061291.117. Epub 2017 Aug 24.

3.

Expression profile of Epstein-Barr virus and human adenovirus small RNAs in tonsillar B and T lymphocytes.

Assadian F, Kamel W, Laurell G, Svensson C, Punga T, Akusjärvi G.

PLoS One. 2017 May 25;12(5):e0177275. doi: 10.1371/journal.pone.0177275. eCollection 2017.

4.

The adenovirus L4-22K protein regulates transcription and RNA splicing via a sequence-specific single-stranded RNA binding.

Lan S, Kamel W, Punga T, Akusjärvi G.

Nucleic Acids Res. 2017 Feb 28;45(4):1731-1742. doi: 10.1093/nar/gkw1145.

5.

Distribution and Molecular Characterization of Human Adenovirus and Epstein-Barr Virus Infections in Tonsillar Lymphocytes Isolated from Patients Diagnosed with Tonsillar Diseases.

Assadian F, Sandström K, Bondeson K, Laurell G, Lidian A, Svensson C, Akusjärvi G, Bergqvist A, Punga T.

PLoS One. 2016 May 2;11(5):e0154814. doi: 10.1371/journal.pone.0154814. eCollection 2016.

6.

HAdV-2-suppressed growth of SV40 T antigen-transformed mouse mammary epithelial cell-induced tumours in SCID mice.

Wu C, Cao X, Yu D, Huijbers EJ, Essand M, Akusjärvi G, Johansson S, Svensson C.

Virology. 2016 Feb;489:44-50. doi: 10.1016/j.virol.2015.11.031. Epub 2015 Dec 18.

7.

Efficient Isolation Protocol for B and T Lymphocytes from Human Palatine Tonsils.

Assadian F, Sandström K, Laurell G, Svensson C, Akusjärvi G, Punga T.

J Vis Exp. 2015 Nov 16;(105). doi: 10.3791/53374.

8.

A suppressive effect of Sp1 recruitment to the first leader 5' splice site region on L4-22K-mediated activation of the adenovirus major late promoter.

Lan S, Östberg S, Punga T, Akusjärvi G.

Virus Res. 2015 Dec 2;210:133-40. doi: 10.1016/j.virusres.2015.07.026. Epub 2015 Aug 3.

PMID:
26247419
9.

Complementation of the human adenovirus type 5 VA RNAI defect by the Vaccinia virus E3L protein and serotype-specific VA RNAIs.

Inturi R, Kamel W, Akusjärvi G, Punga T.

Virology. 2015 Nov;485:25-35. doi: 10.1016/j.virol.2015.07.002. Epub 2015 Jul 18.

10.

Opposite expression of CYP51A1 and its natural antisense transcript AluCYP51A1 in adenovirus type 37 infected retinal pigmented epithelial cells.

Pickl JM, Kamel W, Ciftci S, Punga T, Akusjärvi G.

FEBS Lett. 2015 May 22;589(12):1383-8. doi: 10.1016/j.febslet.2015.04.018. Epub 2015 Apr 20.

11.

Regulation of human adenovirus alternative RNA splicing by the adenoviral L4-33K and L4-22K proteins.

Biasiotto R, Akusjärvi G.

Int J Mol Sci. 2015 Jan 28;16(2):2893-912. doi: 10.3390/ijms16022893. Review.

12.

Poor growth of human adenovirus-12 compared to adenovirus-2 correlates with a failure to impair PKR activation during the late phase of infection.

Wu C, Bai L, Li Z, Samuel CE, Akusjärvi G, Svensson C.

Virology. 2015 Jan 15;475:120-8. doi: 10.1016/j.virol.2014.11.012. Epub 2014 Nov 29.

13.

Small RNA sequence analysis of adenovirus VA RNA-derived miRNAs reveals an unexpected serotype-specific difference in structure and abundance.

Kamel W, Segerman B, Punga T, Akusjärvi G.

PLoS One. 2014 Aug 21;9(8):e105746. doi: 10.1371/journal.pone.0105746. eCollection 2014.

14.

The adenovirus VA RNA-derived miRNAs are not essential for lytic virus growth in tissue culture cells.

Kamel W, Segerman B, Öberg D, Punga T, Akusjärvi G.

Nucleic Acids Res. 2013 May;41(9):4802-12. doi: 10.1093/nar/gkt172. Epub 2013 Mar 21.

15.

A mouse mammary epithelial cell line permissive for highly efficient human adenovirus growth.

Wu C, Öberg D, Rashid A, Gupta R, Mignardi M, Johansson S, Akusjärvi G, Svensson C.

Virology. 2013 Jan 20;435(2):363-71. doi: 10.1016/j.virol.2012.10.034. Epub 2012 Nov 17.

16.

Serine 192 in the tiny RS repeat of the adenoviral L4-33K splicing enhancer protein is essential for function and reorganization of the protein to the periphery of viral replication centers.

Östberg S, Törmänen Persson H, Akusjärvi G.

Virology. 2012 Nov 25;433(2):273-81. doi: 10.1016/j.virol.2012.08.021. Epub 2012 Sep 1.

17.

Protein kinase a-dependent phosphorylation of serine 119 in the proto-oncogenic serine/arginine-rich splicing factor 1 modulates its activity as a splicing enhancer protein.

Aksaas AK, Eikvar S, Akusjärvi G, Skålhegg BS, Kvissel AK.

Genes Cancer. 2011 Aug;2(8):841-51. doi: 10.1177/1947601911430226.

18.

Two cellular protein kinases, DNA-PK and PKA, phosphorylate the adenoviral L4-33K protein and have opposite effects on L1 alternative RNA splicing.

Törmänen Persson H, Aksaas AK, Kvissel AK, Punga T, Engström Å, Skålhegg BS, Akusjärvi G.

PLoS One. 2012;7(2):e31871. doi: 10.1371/journal.pone.0031871. Epub 2012 Feb 21.

19.

Characterization of RISC-associated adenoviral small RNAs.

Xu N, Akusjärvi G.

Methods Mol Biol. 2011;721:183-98. doi: 10.1007/978-1-61779-037-9_11.

PMID:
21431686
20.

Antibody-dependent natural killer cell-mediated cytotoxicity engendered by a kinase-inactive human HER2 adenovirus-based vaccination mediates resistance to breast tumors.

Triulzi C, Vertuani S, Curcio C, Antognoli A, Seibt J, Akusjärvi G, Wei WZ, Cavallo F, Kiessling R.

Cancer Res. 2010 Oct 1;70(19):7431-41. doi: 10.1158/0008-5472.CAN-10-0493. Epub 2010 Sep 7.

21.

Adenovirus L4-22K stimulates major late transcription by a mechanism requiring the intragenic late-specific transcription factor-binding site.

Backström E, Kaufmann KB, Lan X, Akusjärvi G.

Virus Res. 2010 Aug;151(2):220-8. doi: 10.1016/j.virusres.2010.05.013.

PMID:
20621673
22.

Single molecule analysis of combinatorial splicing.

Conze T, Göransson J, Razzaghian HR, Ericsson O, Oberg D, Akusjärvi G, Landegren U, Nilsson M.

Nucleic Acids Res. 2010 Sep;38(16):e163. doi: 10.1093/nar/gkq581. Epub 2010 Jun 29.

23.

The 5'-end heterogeneity of adenovirus virus-associated RNAI contributes to the asymmetric guide strand incorporation into the RNA-induced silencing complex.

Xu N, Gkountela S, Saeed K, Akusjärvi G.

Nucleic Acids Res. 2009 Nov;37(20):6950-9. doi: 10.1093/nar/gkp764. Epub 2009 Sep 15.

24.

Adenovirus E4orf4 induces HPV-16 late L1 mRNA production.

Somberg M, Rush M, Fay J, Ryan F, Lambkin H, Akusjärvi G, Schwartz S.

Virology. 2009 Jan 20;383(2):279-90. doi: 10.1016/j.virol.2008.09.041. Epub 2008 Nov 20.

25.

Glucolipotoxicity in INS-1E cells is counteracted by carnitine palmitoyltransferase 1 over-expression.

Sol EM, Sargsyan E, Akusjärvi G, Bergsten P.

Biochem Biophys Res Commun. 2008 Oct 31;375(4):517-21. doi: 10.1016/j.bbrc.2008.08.013. Epub 2008 Aug 13.

PMID:
18706397
26.

Glucose-induced cyclic AMP oscillations regulate pulsatile insulin secretion.

Dyachok O, Idevall-Hagren O, Sågetorp J, Tian G, Wuttke A, Arrieumerlou C, Akusjärvi G, Gylfe E, Tengholm A.

Cell Metab. 2008 Jul;8(1):26-37. doi: 10.1016/j.cmet.2008.06.003.

27.

Temporal regulation of adenovirus major late alternative RNA splicing.

Akusjarvi G.

Front Biosci. 2008 May 1;13:5006-15. Review.

PMID:
18508565
28.

In vitro methods to study RNA interference during an adenovirus infection.

Andersson G, Xu N, Akusjärvi G.

Methods Mol Med. 2007;131:47-61.

PMID:
17656774
29.

Preparation of soluble extracts from adenovirus-infected cells for studies of RNA splicing.

Mühlemann O, Akusjärvi G.

Methods Mol Med. 2007;131:33-46.

PMID:
17656773
30.
31.

Involvement of the catalytic subunit of protein kinase A and of HA95 in pre-mRNA splicing.

Kvissel AK, Ørstavik S, Eikvar S, Brede G, Jahnsen T, Collas P, Akusjärvi G, Skålhegg BS.

Exp Cell Res. 2007 Aug 1;313(13):2795-809. Epub 2007 May 18.

PMID:
17594903
32.

L4-33K, an adenovirus-encoded alternative RNA splicing factor.

Törmänen H, Backström E, Carlsson A, Akusjärvi G.

J Biol Chem. 2006 Dec 1;281(48):36510-7. Epub 2006 Oct 6.

34.

Binary AdEasy vector systems designed for Tet-ON or Tet-OFF regulated control of transgene expression.

Berenjian S, Akusjärvi G.

Virus Res. 2006 Jan;115(1):16-23. Epub 2005 Aug 15.

PMID:
16102868
35.

Suppression of RNA interference by adenovirus virus-associated RNA.

Andersson MG, Haasnoot PC, Xu N, Berenjian S, Berkhout B, Akusjärvi G.

J Virol. 2005 Aug;79(15):9556-65.

36.

Substrate-dependent differences in U2AF requirement for splicing in adenovirus-infected cell extracts.

Lützelberger M, Backström E, Akusjärvi G.

J Biol Chem. 2005 Jul 8;280(27):25478-84. Epub 2005 May 16.

37.
39.

Precursor of human adenovirus core polypeptide Mu targets the nucleolus and modulates the expression of E2 proteins.

Lee TW, Lawrence FJ, Dauksaite V, Akusjärvi G, Blair GE, Matthews DA.

J Gen Virol. 2004 Jan;85(Pt 1):185-96.

PMID:
14718634
40.
41.

Remodelling of the host cell RNA splicing machinery during an adenovirus infection.

Akusjärvi G, Stévenin J.

Curr Top Microbiol Immunol. 2003;272:253-86. Review.

PMID:
12747553
42.
43.

Functional inactivation of the SR family of splicing factors during a vaccinia virus infection.

Huang TS, Nilsson CE, Punga T, Akusjarvi G.

EMBO Rep. 2002 Nov;3(11):1088-93. Epub 2002 Oct 22.

44.

Unscheduled expression of capsid protein IIIa results in defects in adenovirus major late mRNA and protein expression.

Molin M, Bouakaz L, Berenjian S, Akusjärvi G.

Virus Res. 2002 Feb 26;83(1-2):197-206.

PMID:
11864752
45.

Human splicing factor ASF/SF2 encodes for a repressor domain required for its inhibitory activity on pre-mRNA splicing.

Dauksaite V, Akusjärvi G.

J Biol Chem. 2002 Apr 12;277(15):12579-86. Epub 2002 Jan 18.

46.

Adenovirus vector designed for expression of toxic proteins.

Edholm D, Molin M, Bajak E, Akusjärvi G.

J Virol. 2001 Oct;75(20):9579-84.

47.

Cisplatin induces the proapoptotic conformation of Bak in a deltaMEKK1-dependent manner.

Mandic A, Viktorsson K, Molin M, Akusjärvi G, Eguchi H, Hayashi SI, Toi M, Hansson J, Linder S, Shoshan MC.

Mol Cell Biol. 2001 Jun;21(11):3684-91.

48.

Increased apoptosis and increased clonogenic survival of 12V-H-ras transformed rat fibroblasts in response to cisplatin.

Viktorsson K, Heiden T, Molin M, Akusjärvi G, Linder S, Shoshan MC.

Apoptosis. 2000 Oct;5(4):355-67.

PMID:
11227217
49.

The adenovirus E4-ORF4 splicing enhancer protein interacts with a subset of phosphorylated SR proteins.

Estmer Nilsson C, Petersen-Mahrt S, Durot C, Shtrichman R, Krainer AR, Kleinberger T, Akusjärvi G.

EMBO J. 2001 Feb 15;20(4):864-71.

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