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Items: 1 to 50 of 58

1.

Correction: Exploratory genome-wide association analysis of response to ketamine and a polygenic analysis of response to scopolamine in depression.

Guo W, Machado-Vieira R, Mathew S, Murrough JW, Charney DS, Grunebaum M, Oquendo MA, Kadriu B, Akula N, Henter I, Yuan P, Merikangas K, Drevets W, Furey M, Mann JJ, McMahon FJ, Zarate CA Jr, Shugart YY.

Transl Psychiatry. 2019 Mar 5;9(1):108. doi: 10.1038/s41398-019-0442-5.

2.

Exploratory genome-wide association analysis of response to ketamine and a polygenic analysis of response to scopolamine in depression.

Guo W, Machado-Vieira R, Mathew S, Murrough JW, Charney DS, Grunebaum M, Oquendo MA, Kadriu B, Akula N, Henter I, Yuan P, Merikangas K, Drevets W, Furey M, Mann JJ, McMahon FJ, Zarate CA Jr, Shugart YY.

Transl Psychiatry. 2018 Dec 14;8(1):280. doi: 10.1038/s41398-018-0311-7. Erratum in: Transl Psychiatry. 2019 Mar 5;9(1):108.

3.

Sodium valproate rescues expression of TRANK1 in iPSC-derived neural cells that carry a genetic variant associated with serious mental illness.

Jiang X, Detera-Wadleigh SD, Akula N, Mallon BS, Hou L, Xiao T, Felsenfeld G, Gu X, McMahon FJ.

Mol Psychiatry. 2019 Apr;24(4):613-624. doi: 10.1038/s41380-018-0207-1. Epub 2018 Aug 22.

PMID:
30135510
4.

Investigating polygenic burden in age at disease onset in bipolar disorder: Findings from an international multicentric study.

Kalman JL, Papiol S, Forstner AJ, Heilbronner U, Degenhardt F, Strohmaier J, Adli M, Adorjan K, Akula N, Alda M, Anderson-Schmidt H, Andlauer TF, Anghelescu IG, Ardau R, Arias B, Arolt V, Aubry JM, Backlund L, Bartholdi K, Bauer M, Baune BT, Becker T, Bellivier F, Benabarre A, Bengesser S, Bhattacharjee AK, Biernacka JM, Birner A, Brichant-Petitjean C, Budde M, Cervantes P, Chillotti C, Cichon S, Clark SR, Colom F, Comes AL, Cruceanu C, Czerski PM, Dannlowski U, Dayer A, Del Zompo M, DePaulo JR, Dietrich DE, Étain B, Ethofer T, Falkai P, Fallgatter A, Figge C, Flatau L, Folkerts H, Frisen L, Frye MA, Fullerton JM, Gade K, Gard S, Garnham JS, Goes FS, Grigoroiu-Serbanescu M, Gryaznova A, Hake M, Hauser J, Herms S, Hoffmann P, Hou L, Jäger M, Jamain S, Jiménez E, Juckel G, Kahn JP, Kassem L, Kelsoe J, Kittel-Schneider S, Kliwicki S, Klohn-Sagatholislam F, Koller M, König B, Konrad C, Lackner N, Laje G, Landén M, Lang FU, Lavebratt C, Leboyer M, Leckband SG, Maj M, Manchia M, Martinsson L, McCarthy MJ, McElroy SL, McMahon FJ, Mitchell PB, Mitjans M, Mondimore FM, Monteleone P, Nieratschker V, Nievergelt CM, Novák T, Ösby U, Pfennig A, Potash JB, Reich-Erkelenz D, Reif A, Reimer J, Reininghaus E, Reitt M, Ripke S, Rouleau GA, Rybakowski JK, Schalling M, Scherk H, Schmauß M, Schofield PR, Schubert KO, Schulte EC, Schulz S, Senner F, Severino G, Shekhtman T, Shilling PD, Simhandl C, Slaney CM, Spitzer C, Squassina A, Stamm T, Stegmaier S, Stierl S, Stopkova P, Thiel A, Tighe SK, Tortorella A, Turecki G, Vieta E, Veeh J, von Hagen M, Wigand ME, Wiltfang J, Witt S, Wright A, Zandi PP, Zimmermann J, Nöthen M, Rietschel M, Schulze TG.

Bipolar Disord. 2019 Feb;21(1):68-75. doi: 10.1111/bdi.12659. Epub 2018 Jun 28.

5.

Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder.

Reinbold CS, Forstner AJ, Hecker J, Fullerton JM, Hoffmann P, Hou L, Heilbronner U, Degenhardt F, Adli M, Akiyama K, Akula N, Ardau R, Arias B, Backlund L, Benabarre A, Bengesser S, Bhattacharjee AK, Biernacka JM, Birner A, Marie-Claire C, Cervantes P, Chen GB, Chen HC, Chillotti C, Clark SR, Colom F, Cousins DA, Cruceanu C, Czerski PM, Dayer A, Étain B, Falkai P, Frisén L, Gard S, Garnham JS, Goes FS, Grof P, Gruber O, Hashimoto R, Hauser J, Herms S, Jamain S, Jiménez E, Kahn JP, Kassem L, Kittel-Schneider S, Kliwicki S, König B, Kusumi I, Lackner N, Laje G, Landén M, Lavebratt C, Leboyer M, Leckband SG, López Jaramillo CA, MacQueen G, Manchia M, Martinsson L, Mattheisen M, McCarthy MJ, McElroy SL, Mitjans M, Mondimore FM, Monteleone P, Nievergelt CM, Ösby U, Ozaki N, Perlis RH, Pfennig A, Reich-Erkelenz D, Rouleau GA, Schofield PR, Schubert KO, Schweizer BW, Seemüller F, Severino G, Shekhtman T, Shilling PD, Shimoda K, Simhandl C, Slaney CM, Smoller JW, Squassina A, Stamm TJ, Stopkova P, Tighe SK, Tortorella A, Turecki G, Volkert J, Witt SH, Wright AJ, Young LT, Zandi PP, Potash JB, DePaulo JR, Bauer M, Reininghaus E, Novák T, Aubry JM, Maj M, Baune BT, Mitchell PB, Vieta E, Frye MA, Rybakowski JK, Kuo PH, Kato T, Grigoroiu-Serbanescu M, Reif A, Del Zompo M, Bellivier F, Schalling M, Wray NR, Kelsoe JR, Alda M, McMahon FJ, Schulze TG, Rietschel M, Nöthen MM, Cichon S.

Front Psychiatry. 2018 May 31;9:207. doi: 10.3389/fpsyt.2018.00207. eCollection 2018.

6.

Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study.

International Consortium on Lithium Genetics (ConLi+Gen), Amare AT, Schubert KO, Hou L, Clark SR, Papiol S, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hsu YH, Shekhtman T, Adli M, Akula N, Akiyama K, Ardau R, Arias B, Aubry JM, Backlund L, Bhattacharjee AK, Bellivier F, Benabarre A, Bengesser S, Biernacka JM, Birner A, Brichant-Petitjean C, Cervantes P, Chen HC, Chillotti C, Cichon S, Cruceanu C, Czerski PM, Dalkner N, Dayer A, Del Zompo M, DePaulo JR, Étain B, Falkai P, Forstner AJ, Frisen L, Frye MA, Fullerton JM, Gard S, Garnham JS, Goes FS, Grigoroiu-Serbanescu M, Grof P, Hashimoto R, Hauser J, Herms S, Hoffmann P, Hofmann A, Jamain S, Jiménez E, Kahn JP, Kassem L, Kuo PH, Kato T, Kelsoe J, Kittel-Schneider S, Kliwicki S, König B, Kusumi I, Laje G, Landén M, Lavebratt C, Leboyer M, Leckband SG, Tortorella A, Manchia M, Martinsson L, McCarthy MJ, McElroy S, Colom F, Mitjans M, Mondimore FM, Monteleone P, Nievergelt CM, Nöthen MM, Novák T, O'Donovan C, Ozaki N, Ösby U, Pfennig A, Potash JB, Reif A, Reininghaus E, Rouleau GA, Rybakowski JK, Schalling M, Schofield PR, Schweizer BW, Severino G, Shilling PD, Shimoda K, Simhandl C, Slaney CM, Squassina A, Stamm T, Stopkova P, Maj M, Turecki G, Vieta E, Volkert J, Witt S, Wright A, Zandi PP, Mitchell PB, Bauer M, Alda M, Rietschel M, McMahon FJ, Schulze TG, Baune BT.

JAMA Psychiatry. 2018 Jan 1;75(1):65-74. doi: 10.1001/jamapsychiatry.2017.3433.

7.

The antidepressant efficacy of subanesthetic-dose ketamine does not correlate with baseline subcortical volumes in a replication sample with major depressive disorder.

Niciu MJ, Iadarola ND, Banerjee D, Luckenbaugh DA, Park M, Lener M, Park L, Ionescu DF, Ballard ED, Brutsche NE, Akula N, McMahon FJ, Machado-Vieira R, Nugent AC, Zarate CA Jr.

J Psychopharmacol. 2017 Dec;31(12):1570-1577. doi: 10.1177/0269881117732514. Epub 2017 Oct 17.

8.

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder.

Hou L, Bergen SE, Akula N, Song J, Hultman CM, Landén M, Adli M, Alda M, Ardau R, Arias B, Aubry JM, Backlund L, Badner JA, Barrett TB, Bauer M, Baune BT, Bellivier F, Benabarre A, Bengesser S, Berrettini WH, Bhattacharjee AK, Biernacka JM, Birner A, Bloss CS, Brichant-Petitjean C, Bui ET, Byerley W, Cervantes P, Chillotti C, Cichon S, Colom F, Coryell W, Craig DW, Cruceanu C, Czerski PM, Davis T, Dayer A, Degenhardt F, Del Zompo M, DePaulo JR, Edenberg HJ, Étain B, Falkai P, Foroud T, Forstner AJ, Frisén L, Frye MA, Fullerton JM, Gard S, Garnham JS, Gershon ES, Goes FS, Greenwood TA, Grigoroiu-Serbanescu M, Hauser J, Heilbronner U, Heilmann-Heimbach S, Herms S, Hipolito M, Hitturlingappa S, Hoffmann P, Hofmann A, Jamain S, Jiménez E, Kahn JP, Kassem L, Kelsoe JR, Kittel-Schneider S, Kliwicki S, Koller DL, König B, Lackner N, Laje G, Lang M, Lavebratt C, Lawson WB, Leboyer M, Leckband SG, Liu C, Maaser A, Mahon PB, Maier W, Maj M, Manchia M, Martinsson L, McCarthy MJ, McElroy SL, McInnis MG, McKinney R, Mitchell PB, Mitjans M, Mondimore FM, Monteleone P, Mühleisen TW, Nievergelt CM, Nöthen MM, Novák T, Nurnberger JI Jr, Nwulia EA, Ösby U, Pfennig A, Potash JB, Propping P, Reif A, Reininghaus E, Rice J, Rietschel M, Rouleau GA, Rybakowski JK, Schalling M, Scheftner WA, Schofield PR, Schork NJ, Schulze TG, Schumacher J, Schweizer BW, Severino G, Shekhtman T, Shilling PD, Simhandl C, Slaney CM, Smith EN, Squassina A, Stamm T, Stopkova P, Streit F, Strohmaier J, Szelinger S, Tighe SK, Tortorella A, Turecki G, Vieta E, Volkert J, Witt SH, Wright A, Zandi PP, Zhang P, Zollner S, McMahon FJ.

Hum Mol Genet. 2016 Aug 1;25(15):3383-3394. doi: 10.1093/hmg/ddw181. Epub 2016 Jun 21.

9.

Development of a Microemulsion Formulation for Antimicrobial SecA Inhibitors.

Hu J, Akula N, Wang N.

PLoS One. 2016 Mar 10;11(3):e0150433. doi: 10.1371/journal.pone.0150433. eCollection 2016.

10.

Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study.

Hou L, Heilbronner U, Degenhardt F, Adli M, Akiyama K, Akula N, Ardau R, Arias B, Backlund L, Banzato CEM, Benabarre A, Bengesser S, Bhattacharjee AK, Biernacka JM, Birner A, Brichant-Petitjean C, Bui ET, Cervantes P, Chen GB, Chen HC, Chillotti C, Cichon S, Clark SR, Colom F, Cousins DA, Cruceanu C, Czerski PM, Dantas CR, Dayer A, Étain B, Falkai P, Forstner AJ, Frisén L, Fullerton JM, Gard S, Garnham JS, Goes FS, Grof P, Gruber O, Hashimoto R, Hauser J, Herms S, Hoffmann P, Hofmann A, Jamain S, Jiménez E, Kahn JP, Kassem L, Kittel-Schneider S, Kliwicki S, König B, Kusumi I, Lackner N, Laje G, Landén M, Lavebratt C, Leboyer M, Leckband SG, Jaramillo CAL, MacQueen G, Manchia M, Martinsson L, Mattheisen M, McCarthy MJ, McElroy SL, Mitjans M, Mondimore FM, Monteleone P, Nievergelt CM, Nöthen MM, Ösby U, Ozaki N, Perlis RH, Pfennig A, Reich-Erkelenz D, Rouleau GA, Schofield PR, Schubert KO, Schweizer BW, Seemüller F, Severino G, Shekhtman T, Shilling PD, Shimoda K, Simhandl C, Slaney CM, Smoller JW, Squassina A, Stamm T, Stopkova P, Tighe SK, Tortorella A, Turecki G, Volkert J, Witt S, Wright A, Young LT, Zandi PP, Potash JB, DePaulo JR, Bauer M, Reininghaus EZ, Novák T, Aubry JM, Maj M, Baune BT, Mitchell PB, Vieta E, Frye MA, Rybakowski JK, Kuo PH, Kato T, Grigoroiu-Serbanescu M, Reif A, Del Zompo M, Bellivier F, Schalling M, Wray NR, Kelsoe JR, Alda M, Rietschel M, McMahon FJ, Schulze TG.

Lancet. 2016 Mar 12;387(10023):1085-1093. doi: 10.1016/S0140-6736(16)00143-4. Epub 2016 Jan 22.

11.

An Integrative Genomic Study Implicates the Postsynaptic Density in the Pathogenesis of Bipolar Disorder.

Akula N, Wendland JR, Choi KH, McMahon FJ.

Neuropsychopharmacology. 2016 Feb;41(3):886-95. doi: 10.1038/npp.2015.218. Epub 2015 Jul 27.

12.
13.

Rare variants in neuronal excitability genes influence risk for bipolar disorder.

Ament SA, Szelinger S, Glusman G, Ashworth J, Hou L, Akula N, Shekhtman T, Badner JA, Brunkow ME, Mauldin DE, Stittrich AB, Rouleau K, Detera-Wadleigh SD, Nurnberger JI Jr, Edenberg HJ, Gershon ES, Schork N; Bipolar Genome Study, Price ND, Gelinas R, Hood L, Craig D, McMahon FJ, Kelsoe JR, Roach JC.

Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):3576-81. doi: 10.1073/pnas.1424958112. Epub 2015 Feb 17.

14.

RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms and GTPase binding in bipolar disorder.

Akula N, Barb J, Jiang X, Wendland JR, Choi KH, Sen SK, Hou L, Chen DT, Laje G, Johnson K, Lipska BK, Kleinman JE, Corrada-Bravo H, Detera-Wadleigh S, Munson PJ, McMahon FJ.

Mol Psychiatry. 2014 Nov;19(11):1179-85. doi: 10.1038/mp.2013.170. Epub 2014 Jan 7.

15.

Association study of 83 candidate genes for bipolar disorder in chromosome 6q selected using an evidence-based prioritization algorithm.

Bigdeli TB, Maher BS, Zhao Z, Sun J, Medeiros H, Akula N, McMahon FJ, Carvalho C, Ferreira SR, Azevedo MH, Knowles JA, Pato MT, Pato CN, Fanous AH.

Am J Med Genet B Neuropsychiatr Genet. 2013 Dec;162B(8):898-906. doi: 10.1002/ajmg.b.32200. Epub 2013 Sep 30.

PMID:
24123842
16.

Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: A Consortium on Lithium Genetics (ConLiGen) Report.

Manchia M, Adli M, Akula N, Ardau R, Aubry JM, Backlund L, Banzato CE, Baune BT, Bellivier F, Bengesser S, Biernacka JM, Brichant-Petitjean C, Bui E, Calkin CV, Cheng AT, Chillotti C, Cichon S, Clark S, Czerski PM, Dantas C, Zompo MD, Depaulo JR, Detera-Wadleigh SD, Etain B, Falkai P, Frisén L, Frye MA, Fullerton J, Gard S, Garnham J, Goes FS, Grof P, Gruber O, Hashimoto R, Hauser J, Heilbronner U, Hoban R, Hou L, Jamain S, Kahn JP, Kassem L, Kato T, Kelsoe JR, Kittel-Schneider S, Kliwicki S, Kuo PH, Kusumi I, Laje G, Lavebratt C, Leboyer M, Leckband SG, López Jaramillo CA, Maj M, Malafosse A, Martinsson L, Masui T, Mitchell PB, Mondimore F, Monteleone P, Nallet A, Neuner M, Novák T, O'Donovan C, Osby U, Ozaki N, Perlis RH, Pfennig A, Potash JB, Reich-Erkelenz D, Reif A, Reininghaus E, Richardson S, Rouleau GA, Rybakowski JK, Schalling M, Schofield PR, Schubert OK, Schweizer B, Seemüller F, Grigoroiu-Serbanescu M, Severino G, Seymour LR, Slaney C, Smoller JW, Squassina A, Stamm T, Steele J, Stopkova P, Tighe SK, Tortorella A, Turecki G, Wray NR, Wright A, Zandi PP, Zilles D, Bauer M, Rietschel M, McMahon FJ, Schulze TG, Alda M.

PLoS One. 2013 Jun 19;8(6):e65636. doi: 10.1371/journal.pone.0065636. Print 2013.

17.

Race, genetic ancestry and response to antidepressant treatment for major depression.

Murphy E, Hou L, Maher BS, Woldehawariat G, Kassem L, Akula N, Laje G, McMahon FJ.

Neuropsychopharmacology. 2013 Dec;38(13):2598-606. doi: 10.1038/npp.2013.166. Epub 2013 Jul 5.

18.

Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy.

Morgan RA, Chinnasamy N, Abate-Daga D, Gros A, Robbins PF, Zheng Z, Dudley ME, Feldman SA, Yang JC, Sherry RM, Phan GQ, Hughes MS, Kammula US, Miller AD, Hessman CJ, Stewart AA, Restifo NP, Quezado MM, Alimchandani M, Rosenberg AZ, Nath A, Wang T, Bielekova B, Wuest SC, Akula N, McMahon FJ, Wilde S, Mosetter B, Schendel DJ, Laurencot CM, Rosenberg SA.

J Immunother. 2013 Feb;36(2):133-51. doi: 10.1097/CJI.0b013e3182829903.

19.

Replication and meta-analysis of TMEM132D gene variants in panic disorder.

Erhardt A, Akula N, Schumacher J, Czamara D, Karbalai N, Müller-Myhsok B, Mors O, Borglum A, Kristensen AS, Woldbye DP, Koefoed P, Eriksson E, Maron E, Metspalu A, Nurnberger J, Philibert RA, Kennedy J, Domschke K, Reif A, Deckert J, Otowa T, Kawamura Y, Kaiya H, Okazaki Y, Tanii H, Tokunaga K, Sasaki T, Ioannidis JP, McMahon FJ, Binder EB.

Transl Psychiatry. 2012 Sep 4;2:e156. doi: 10.1038/tp.2012.85.

20.

Brain-derived neurotrophic factor Val66Met polymorphism and antidepressant efficacy of ketamine in depressed patients.

Laje G, Lally N, Mathews D, Brutsche N, Chemerinski A, Akula N, Kelmendi B, Simen A, McMahon FJ, Sanacora G, Zarate C Jr.

Biol Psychiatry. 2012 Dec 1;72(11):e27-8. doi: 10.1016/j.biopsych.2012.05.031. Epub 2012 Jul 6. No abstract available.

21.

Identification of small molecule inhibitors against SecA of Candidatus Liberibacter asiaticus by structure based design.

Akula N, Trivedi P, Han FQ, Wang N.

Eur J Med Chem. 2012 Aug;54:919-24. doi: 10.1016/j.ejmech.2012.05.035. Epub 2012 Jun 2.

PMID:
22703844
22.

Identification of small-molecule inhibitors of the steroidogenic acute regulatory protein (STARD1) by structure-based design.

Akula N, Midzak A, Lecanu L, Papadopoulos V.

Bioorg Med Chem Lett. 2012 Jun 15;22(12):4139-43. doi: 10.1016/j.bmcl.2012.04.058. Epub 2012 Apr 19.

PMID:
22575868
23.

Molecular genetic overlap in bipolar disorder, schizophrenia, and major depressive disorder.

Schulze TG, Akula N, Breuer R, Steele J, Nalls MA, Singleton AB, Degenhardt FA, Nöthen MM, Cichon S, Rietschel M; Bipolar Genome Study, McMahon FJ.

World J Biol Psychiatry. 2014 Apr;15(3):200-8. doi: 10.3109/15622975.2012.662282. Epub 2012 Mar 9.

24.

Identity-by-descent filtering as a tool for the identification of disease alleles in exome sequence data from distant relatives.

Akula N, Detera-Wadleigh S, Shugart YY, Nalls M, Steele J, McMahon FJ.

BMC Proc. 2011 Nov 29;5 Suppl 9:S76. doi: 10.1186/1753-6561-5-S9-S76.

25.

Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.

Chen DT, Jiang X, Akula N, Shugart YY, Wendland JR, Steele CJ, Kassem L, Park JH, Chatterjee N, Jamain S, Cheng A, Leboyer M, Muglia P, Schulze TG, Cichon S, Nöthen MM, Rietschel M; BiGS, McMahon FJ, Farmer A, McGuffin P, Craig I, Lewis C, Hosang G, Cohen-Woods S, Vincent JB, Kennedy JL, Strauss J.

Mol Psychiatry. 2013 Feb;18(2):195-205. doi: 10.1038/mp.2011.157. Epub 2011 Dec 20. Erratum in: Mol Psychiatry. 2013 Feb;18(2):264-6. Farmer, A [added]; McGuffin, P [added]; Craig, I [added]; Lewis, C [added]; Hosang, G [added]; Cohen-Woods, S [added]; Vincent, J B [added]; Kennedy, J L [added]; Strauss, J [added].

PMID:
22182935
26.

A network-based approach to prioritize results from genome-wide association studies.

Akula N, Baranova A, Seto D, Solka J, Nalls MA, Singleton A, Ferrucci L, Tanaka T, Bandinelli S, Cho YS, Kim YJ, Lee JY, Han BG; Bipolar Disorder Genome Study (BiGS) Consortium; Wellcome Trust Case-Control Consortium, McMahon FJ.

PLoS One. 2011;6(9):e24220. doi: 10.1371/journal.pone.0024220. Epub 2011 Sep 6.

27.

Discovery of novel SecA inhibitors of Candidatus Liberibacter asiaticus by structure based design.

Akula N, Zheng H, Han FQ, Wang N.

Bioorg Med Chem Lett. 2011 Jul 15;21(14):4183-8. doi: 10.1016/j.bmcl.2011.05.086. Epub 2011 May 30.

PMID:
21684161
28.

A systems approach to the biology of mood disorders through network analysis of candidate genes.

Detera-Wadleigh SD, Akula N.

Pharmacopsychiatry. 2011 May;44 Suppl 1:S35-42. doi: 10.1055/s-0031-1275275. Epub 2011 May 5.

PMID:
21547870
29.

Interaction networks of lithium and valproate molecular targets reveal a striking enrichment of apoptosis functional clusters and neurotrophin signaling.

Gupta A, Schulze TG, Nagarajan V, Akula N, Corona W, Jiang XY, Hunter N, McMahon FJ, Detera-Wadleigh SD.

Pharmacogenomics J. 2012 Aug;12(4):328-41. doi: 10.1038/tpj.2011.9. Epub 2011 Mar 8.

30.

A non-synonymous polymorphism in galactose mutarotase (GALM) is associated with serotonin transporter binding potential in the human thalamus: results of a genome-wide association study.

Liu X, Cannon DM, Akula N, Moya PR, Knudsen GM, Arentzen TE, Steele J, Laje G, Drevets WC, McMahon FJ.

Mol Psychiatry. 2011 Jun;16(6):584-5. doi: 10.1038/mp.2011.1. Epub 2011 Feb 22. No abstract available.

31.

Presence of mechanical dyssynchrony in Duchenne muscular dystrophy.

Hor KN, Wansapura JP, Al-Khalidi HR, Gottliebson WM, Taylor MD, Czosek RJ, Nagueh SF, Akula N, Chung ES, Benson WD, Mazur W.

J Cardiovasc Magn Reson. 2011 Feb 2;13:12. doi: 10.1186/1532-429X-13-12.

32.

Accuracy of CNV Detection from GWAS Data.

Zhang D, Qian Y, Akula N, Alliey-Rodriguez N, Tang J; Bipolar Genome Study, Gershon ES, Liu C.

PLoS One. 2011 Jan 13;6(1):e14511. doi: 10.1371/journal.pone.0014511.

33.

Novel androstenetriol interacts with the mitochondrial translocator protein and controls steroidogenesis.

Midzak A, Akula N, Lecanu L, Papadopoulos V.

J Biol Chem. 2011 Mar 18;286(11):9875-87. doi: 10.1074/jbc.M110.203216. Epub 2011 Jan 5.

34.

Homology modeling and QSAR analysis of 1,3,4-thiadiazole and 1,3,4-triazole derivatives as carbonic anhydrase inhibitors.

Akula NV, Kumar S, Singh V, Tiwari M.

Indian J Biochem Biophys. 2010 Aug;47(4):234-42.

PMID:
21174951
35.

Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders.

Rupprecht R, Papadopoulos V, Rammes G, Baghai TC, Fan J, Akula N, Groyer G, Adams D, Schumacher M.

Nat Rev Drug Discov. 2010 Dec;9(12):971-88. doi: 10.1038/nrd3295. Review.

PMID:
21119734
36.

The International Consortium on Lithium Genetics (ConLiGen): an initiative by the NIMH and IGSLI to study the genetic basis of response to lithium treatment.

Schulze TG, Alda M, Adli M, Akula N, Ardau R, Bui ET, Chillotti C, Cichon S, Czerski P, Del Zompo M, Detera-Wadleigh SD, Grof P, Gruber O, Hashimoto R, Hauser J, Hoban R, Iwata N, Kassem L, Kato T, Kittel-Schneider S, Kliwicki S, Kelsoe JR, Kusumi I, Laje G, Leckband SG, Manchia M, Macqueen G, Masui T, Ozaki N, Perlis RH, Pfennig A, Piccardi P, Richardson S, Rouleau G, Reif A, Rybakowski JK, Sasse J, Schumacher J, Severino G, Smoller JW, Squassina A, Turecki G, Young LT, Yoshikawa T, Bauer M, McMahon FJ.

Neuropsychobiology. 2010;62(1):72-8. doi: 10.1159/000314708. Epub 2010 May 8.

37.

Genetic variation in cholinergic muscarinic-2 receptor gene modulates M2 receptor binding in vivo and accounts for reduced binding in bipolar disorder.

Cannon DM, Klaver JK, Gandhi SK, Solorio G, Peck SA, Erickson K, Akula N, Savitz J, Eckelman WC, Furey ML, Sahakian BJ, McMahon FJ, Drevets WC.

Mol Psychiatry. 2011 Apr;16(4):407-18. doi: 10.1038/mp.2010.24. Epub 2010 Mar 30.

38.

A genome-wide association study of amygdala activation in youths with and without bipolar disorder.

Liu X, Akula N, Skup M, Brotman MA, Leibenluft E, McMahon FJ.

J Am Acad Child Adolesc Psychiatry. 2010 Jan;49(1):33-41.

39.

Meta-analysis of genome-wide association data identifies a risk locus for major mood disorders on 3p21.1.

McMahon FJ, Akula N, Schulze TG, Muglia P, Tozzi F, Detera-Wadleigh SD, Steele CJ, Breuer R, Strohmaier J, Wendland JR, Mattheisen M, Mühleisen TW, Maier W, Nöthen MM, Cichon S, Farmer A, Vincent JB, Holsboer F, Preisig M, Rietschel M; Bipolar Disorder Genome Study (BiGS) Consortium.

Nat Genet. 2010 Feb;42(2):128-31. doi: 10.1038/ng.523. Epub 2010 Jan 17.

40.

Enhanced ascorbic acid accumulation in transgenic potato confers tolerance to various abiotic stresses.

Hemavathi, Upadhyaya CP, Akula N, Young KE, Chun SC, Kim DH, Park SW.

Biotechnol Lett. 2010 Feb;32(2):321-30. doi: 10.1007/s10529-009-0140-0. Epub 2009 Oct 11.

PMID:
19821071
41.

Genome-wide association study of suicidal ideation emerging during citalopram treatment of depressed outpatients.

Laje G, Allen AS, Akula N, Manji H, John Rush A, McMahon FJ.

Pharmacogenet Genomics. 2009 Sep;19(9):666-74. doi: 10.1097/FPC.0b013e32832e4bcd.

42.

Bcl-2 polymorphism influences gray matter volume in the ventral striatum in healthy humans.

Salvadore G, Nugent AC, Chen G, Akula N, Yuan P, Cannon DM, Zarate CA Jr, McMahon FJ, Manji HK, Drevets WC.

Biol Psychiatry. 2009 Oct 15;66(8):804-7. doi: 10.1016/j.biopsych.2009.05.025. Epub 2009 Jul 9. Erratum in: Biol Psychiatry. 2009 Oct 15;66(8):808.

43.

Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorder.

Schulze TG, Detera-Wadleigh SD, Akula N, Gupta A, Kassem L, Steele J, Pearl J, Strohmaier J, Breuer R, Schwarz M, Propping P, Nöthen MM, Cichon S, Schumacher J; NIMH Genetics Initiative Bipolar Disorder Consortium, Rietschel M, McMahon FJ.

Mol Psychiatry. 2009 May;14(5):487-91. doi: 10.1038/mp.2008.134. Epub 2008 Dec 16.

44.

Sequence variation in DOCK9 and heterogeneity in bipolar disorder.

Detera-Wadleigh SD, Liu CY, Maheshwari M, Cardona I, Corona W, Akula N, Steele CJ, Badner JA, Kundu M, Kassem L, Potash JB, Gibbs R, Gershon ES, McMahon FJ; NIMH Genetics Initiative for Bipolar Disorder Consortium.

Psychiatr Genet. 2007 Oct;17(5):274-86.

PMID:
17728666
45.

Gene-based SNP mapping of a psychotic bipolar affective disorder linkage region on 22q12.3: association with HMG2L1 and TOM1.

Potash JB, Buervenich S, Cox NJ, Zandi PP, Akula N, Steele J, Rathe JA, Avramopoulos D, Detera-Wadleigh SD, Gershon ES, DePaulo JR Jr, Feinberg AP, McMahon FJ; NIMH Genetics Initiative Bipolar Disorder Consortium.

Am J Med Genet B Neuropsychiatr Genet. 2008 Jan 5;147B(1):59-67.

PMID:
17671966
46.

A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder.

Baum AE, Akula N, Cabanero M, Cardona I, Corona W, Klemens B, Schulze TG, Cichon S, Rietschel M, Nöthen MM, Georgi A, Schumacher J, Schwarz M, Abou Jamra R, Höfels S, Propping P, Satagopan J, Detera-Wadleigh SD, Hardy J, McMahon FJ.

Mol Psychiatry. 2008 Feb;13(2):197-207. Epub 2007 May 8.

47.

3D QSAR studies of AChE inhibitors based on molecular docking scores and CoMFA.

Akula N, Lecanu L, Greeson J, Papadopoulos V.

Bioorg Med Chem Lett. 2006 Dec 15;16(24):6277-80. Epub 2006 Oct 16.

PMID:
17049234
48.

Selectivity and potency of cyclin-dependent kinase inhibitors.

Sridhar J, Akula N, Pattabiraman N.

AAPS J. 2006 Mar 24;8(1):E204-21. Review.

49.

Identification of novel angiogenesis inhibitors.

Sridhar J, Akula N, Sivanesan D, Narasimhan M, Rathinavelu A, Pattabiraman N.

Bioorg Med Chem Lett. 2005 Sep 15;15(18):4125-9.

PMID:
15993586
50.

A systematic search method for the identification of tightly packed transmembrane parallel alpha-helices.

Akula N, Pattabiraman N.

J Biomol Struct Dyn. 2005 Jun;22(6):625-34.

PMID:
15842168

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