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Items: 8


Synapses on sympathetic neurons and parasympathetic neurons differ in their vulnerability to diabetes.

Rudchenko A, Akude E, Cooper E.

J Neurosci. 2014 Jun 25;34(26):8865-74. doi: 10.1523/JNEUROSCI.0033-14.2014.


Ciliary neurotrophic factor reverses aberrant mitochondrial bioenergetics through the JAK/STAT pathway in cultured sensory neurons derived from streptozotocin-induced diabetic rodents.

Chowdhury SR, Saleh A, Akude E, Smith DR, Morrow D, Tessler L, Calcutt NA, Fernyhough P.

Cell Mol Neurobiol. 2014 Jul;34(5):643-9. doi: 10.1007/s10571-014-0054-9. Epub 2014 Mar 30.


Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral neuropathy in diabetes.

Roy Chowdhury SK, Smith DR, Saleh A, Schapansky J, Marquez A, Gomes S, Akude E, Morrow D, Calcutt NA, Fernyhough P.

Brain. 2012 Jun;135(Pt 6):1751-66. doi: 10.1093/brain/aws097. Epub 2012 May 4.


Sensory neurons derived from diabetic rats have diminished internal Ca2+ stores linked to impaired re-uptake by the endoplasmic reticulum.

Zherebitskaya E, Schapansky J, Akude E, Smith DR, Van der Ploeg R, Solovyova N, Verkhratsky A, Fernyhough P.

ASN Neuro. 2012 Jan 18;4(1). pii: e00072. doi: 10.1042/AN20110038.


Diminished superoxide generation is associated with respiratory chain dysfunction and changes in the mitochondrial proteome of sensory neurons from diabetic rats.

Akude E, Zherebitskaya E, Chowdhury SK, Smith DR, Dobrowsky RT, Fernyhough P.

Diabetes. 2011 Jan;60(1):288-97. doi: 10.2337/db10-0818. Epub 2010 Sep 28.


Mitochondrial respiratory chain dysfunction in dorsal root ganglia of streptozotocin-induced diabetic rats and its correction by insulin treatment.

Chowdhury SK, Zherebitskaya E, Smith DR, Akude E, Chattopadhyay S, Jolivalt CG, Calcutt NA, Fernyhough P.

Diabetes. 2010 Apr;59(4):1082-91. doi: 10.2337/db09-1299. Epub 2010 Jan 26.


4-Hydroxy-2-nonenal induces mitochondrial dysfunction and aberrant axonal outgrowth in adult sensory neurons that mimics features of diabetic neuropathy.

Akude E, Zherebitskaya E, Roy Chowdhury SK, Girling K, Fernyhough P.

Neurotox Res. 2010 Jan;17(1):28-38. doi: 10.1007/s12640-009-9074-5. Epub 2009 Jun 26.


Development of selective axonopathy in adult sensory neurons isolated from diabetic rats: role of glucose-induced oxidative stress.

Zherebitskaya E, Akude E, Smith DR, Fernyhough P.

Diabetes. 2009 Jun;58(6):1356-64. doi: 10.2337/db09-0034. Epub 2009 Feb 27.

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