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Items: 1 to 50 of 310

1.

Asparaginase-like protein 1 expression in curettage independently predicts lymph node metastasis in endometrial carcinoma: a multicenter study.

Fonnes T, Trovik J, Edqvist PD, Fasmer KE, Marcickiewicz J, Tingulstad S, Staff AC, Bjørge L, Amant F, Haldorsen IS, Werner HM, Akslen LA, Tangen IL, Krakstad C.

BJOG. 2018 Jul 10. doi: 10.1111/1471-0528.15403. [Epub ahead of print]

PMID:
29989298
2.

Automated Volumetric Analysis of Mammographic Density in a Screening Setting: Worse Outcomes for Women with Dense Breasts.

Moshina N, Sebuødegård S, Lee CI, Akslen LA, Tsuruda KM, Elmore JG, Hofvind S.

Radiology. 2018 Jun 26:172972. doi: 10.1148/radiol.2018172972. [Epub ahead of print]

PMID:
29944088
3.

Impact of pre-diagnostic triglycerides and HDL-cholesterol on breast cancer recurrence and survival by breast cancer subtypes.

Lofterød T, Mortensen ES, Nalwoga H, Wilsgaard T, Frydenberg H, Risberg T, Eggen AE, McTiernan A, Aziz S, Wist EA, Stensvold A, Reitan JB, Akslen LA, Thune I.

BMC Cancer. 2018 Jun 15;18(1):654. doi: 10.1186/s12885-018-4568-2.

4.

High mortality due to cutaneous melanoma in Norway: a study of prognostic factors in a nationwide cancer registry.

Robsahm TE, Helsing P, Nilssen Y, Vos L, Rizvi SMH, Akslen LA, Veierød MB.

Clin Epidemiol. 2018 May 9;10:537-548. doi: 10.2147/CLEP.S151246. eCollection 2018.

5.

Microenvironment-Induced Non-sporadic Expression of the AXL and cKIT Receptors Are Related to Epithelial Plasticity and Drug Resistance.

Jokela TA, Engelsen AST, Rybicka A, Pelissier Vatter FA, Garbe JC, Miyano M, Tiron C, Ferariu D, Akslen LA, Stampfer MR, Lorens JB, LaBarge MA.

Front Cell Dev Biol. 2018 Apr 17;6:41. doi: 10.3389/fcell.2018.00041. eCollection 2018.

6.

Tumour cell expression of interleukin 6 receptor α is associated with response rates in patients treated with sunitinib for metastatic clear cell renal cell carcinoma.

Pilskog M, Bostad L, Edelmann RJ, Akslen LA, Beisland C, Straume O.

J Pathol Clin Res. 2018 Apr;4(2):114-123. doi: 10.1002/cjp2.96. Epub 2018 Mar 5.

7.

Low expression of SerpinB2 is associated with reduced survival in lung adenocarcinomas.

Ramnefjell M, Aamelfot C, Helgeland L, Akslen LA.

Oncotarget. 2017 Oct 3;8(53):90706-90718. doi: 10.18632/oncotarget.21456. eCollection 2017 Oct 31.

8.

Prognostic impact and concordance of TERT promoter mutation and protein expression in matched primary and metastatic cutaneous melanoma.

Hugdahl E, Kalvenes MB, Mannelqvist M, Ladstein RG, Akslen LA.

Br J Cancer. 2018 Jan;118(1):98-105. doi: 10.1038/bjc.2017.384. Epub 2017 Nov 9.

PMID:
29123258
9.

Asparaginase-like protein 1 is an independent prognostic marker in primary endometrial cancer, and is frequently lost in metastatic lesions.

Fonnes T, Berg HF, Bredholt T, Edqvist PD, Sortland K, Berg A, Salvesen HB, Akslen LA, Werner HMJ, Trovik J, Tangen IL, Krakstad C.

Gynecol Oncol. 2018 Jan;148(1):197-203. doi: 10.1016/j.ygyno.2017.10.025. Epub 2017 Oct 31.

PMID:
29096882
10.

Microvascular proliferation is associated with aggressive tumour features and reduced survival in lung adenocarcinoma.

Ramnefjell M, Aamelfot C, Aziz S, Helgeland L, Akslen LA.

J Pathol Clin Res. 2017 Sep 12;3(4):249-257. doi: 10.1002/cjp2.78. eCollection 2017 Oct.

11.

Optimising preoperative risk stratification tools for prostate cancer using mpMRI.

Reisæter LAR, Fütterer JJ, Losnegård A, Nygård Y, Monssen J, Gravdal K, Halvorsen OJ, Akslen LA, Biermann M, Haukaas S, Rørvik J, Beisland C.

Eur Radiol. 2018 Mar;28(3):1016-1026. doi: 10.1007/s00330-017-5031-5. Epub 2017 Oct 6.

12.

Preoperative imaging markers and PDZ-binding kinase tissue expression predict low-risk disease in endometrial hyperplasias and low grade cancers.

Berg A, Gulati A, Ytre-Hauge S, Fasmer KE, Mauland KK, Hoivik EA, Husby JA, Tangen IL, Trovik J, Halle MK, Stefansson I, Akslen LA, Woie K, Bjørge L, Salvesen HB, Salvesen ØO, Werner HMJ, Haldorsen IS, Krakstad C.

Oncotarget. 2017 Jul 31;8(40):68530-68541. doi: 10.18632/oncotarget.19708. eCollection 2017 Sep 15.

13.

Expression of glucocorticoid receptor is associated with aggressive primary endometrial cancer and increases from primary to metastatic lesions.

Tangen IL, Veneris JT, Halle MK, Werner HM, Trovik J, Akslen LA, Salvesen HB, Conzen SD, Fleming GF, Krakstad C.

Gynecol Oncol. 2017 Dec;147(3):672-677. doi: 10.1016/j.ygyno.2017.09.013. Epub 2017 Sep 18.

PMID:
28927900
14.

Tumor-associated macrophages are strongly related to vascular invasion, non-luminal subtypes, and interval breast cancer.

Klingen TA, Chen Y, Aas H, Wik E, Akslen LA.

Hum Pathol. 2017 Nov;69:72-80. doi: 10.1016/j.humpath.2017.09.001. Epub 2017 Sep 18.

PMID:
28923419
15.

Predictive value of C-reactive protein in patients treated with sunitinib for metastatic clear cell renal cell carcinoma.

Pilskog M, Beisland C, Akslen LA, Bostad L, Haug Å, Heinrich D, Hjelle KM, Straume O.

BMC Urol. 2017 Aug 31;17(1):74. doi: 10.1186/s12894-017-0267-6.

16.

Expression of Nestin associates with BRCA1 mutations, a basal-like phenotype and aggressive breast cancer.

Krüger K, Wik E, Knutsvik G, Nalwoga H, Klingen TA, Arnes JB, Chen Y, Mannelqvist M, Dimitrakopoulou K, Stefansson IM, Birkeland E, Aas T, Tobin NP, Jonassen I, Bergh J, Foulkes WD, Akslen LA.

Sci Rep. 2017 Apr 24;7(1):1089. doi: 10.1038/s41598-017-00862-w.

17.

Quantifying tumour vascularity in non-luminal breast cancers.

Kraby MR, Opdahl S, Akslen LA, Bofin AM.

J Clin Pathol. 2017 Sep;70(9):766-774. doi: 10.1136/jclinpath-2016-204208. Epub 2017 Mar 1.

PMID:
28249942
18.

Vascular invasion is an adverse prognostic factor in resected non-small-cell lung cancer.

Ramnefjell M, Aamelfot C, Helgeland L, Akslen LA.

APMIS. 2017 Mar;125(3):197-206. doi: 10.1111/apm.12652.

PMID:
28233448
19.

What is responsible cancer research?

Strand R, Akslen LA.

Tidsskr Nor Laegeforen. 2017 Feb 21;137(4):292-294. doi: 10.4045/tidsskr.16.0295. eCollection 2017 Feb. English, Norwegian. No abstract available.

20.

Extra-nodal extension is a significant prognostic factor in lymph node positive breast cancer.

Aziz S, Wik E, Knutsvik G, Klingen TA, Chen Y, Davidsen B, Aas H, Aas T, Akslen LA.

PLoS One. 2017 Feb 15;12(2):e0171853. doi: 10.1371/journal.pone.0171853. eCollection 2017.

21.

FGD5 amplification in breast cancer patients is associated with tumour proliferation and a poorer prognosis.

Valla M, Engstrøm MJ, Ytterhus B, Hansen ÅK, Akslen LA, Vatten LJ, Opdahl S, Bofin AM.

Breast Cancer Res Treat. 2017 Apr;162(2):243-253. doi: 10.1007/s10549-017-4125-8. Epub 2017 Jan 25.

PMID:
28124285
22.

Aneuploidy related transcriptional changes in endometrial cancer link low expression of chromosome 15q genes to poor survival.

Mauland KK, Wik E, Hoivik EA, Kusonmano K, Halle MK, Berg A, Haugland HK, Øyan AM, Kalland KH, Stefansson IM, Akslen LA, Krakstad C, Trovik J, Werner HM, Salvesen HB.

Oncotarget. 2017 Feb 7;8(6):9696-9707. doi: 10.18632/oncotarget.14201.

23.

Molecular Subtypes of Breast Cancer: Long-term Incidence Trends and Prognostic Differences.

Valla M, Vatten LJ, Engstrøm MJ, Haugen OA, Akslen LA, Bjørngaard JH, Hagen AI, Ytterhus B, Bofin AM, Opdahl S.

Cancer Epidemiol Biomarkers Prev. 2016 Dec;25(12):1625-1634. Epub 2016 Sep 26.

24.

Tumour cell invasion into blood vessels is significantly related to breast cancer subtypes and decreased survival.

Klingen TA, Chen Y, Stefansson IM, Knutsvik G, Collett K, Abrahamsen AL, Aase H, Aas H, Aas T, Wik E, Akslen LA.

J Clin Pathol. 2017 Apr;70(4):313-319. doi: 10.1136/jclinpath-2016-203861. Epub 2016 Sep 9.

PMID:
27612505
25.

QSOX1 expression is associated with aggressive tumor features and reduced survival in breast carcinomas.

Knutsvik G, Collett K, Arnes J, Akslen LA, Stefansson IM.

Mod Pathol. 2016 Dec;29(12):1485-1491. doi: 10.1038/modpathol.2016.148. Epub 2016 Aug 26.

26.

Cutaneous head and neck melanoma (CHNM): A population-based study of the prognostic impact of tumor location.

Helsing P, Robsahm TE, Vos L, Rizvi SM, Akslen LA, Veierød MB.

J Am Acad Dermatol. 2016 Nov;75(5):975-982.e2. doi: 10.1016/j.jaad.2016.06.048. Epub 2016 Aug 18.

PMID:
27546291
27.

A Nationwide Study of Multiple Endocrine Neoplasia Type 2A in Norway: Predictive and Prognostic Factors for the Clinical Course of Medullary Thyroid Carcinoma.

Opsahl EM, Brauckhoff M, Schlichting E, Helset K, Svartberg J, Brauckhoff K, Mæhle L, Engebretsen LF, Sigstad E, Grøholt KK, Akslen LA, Jørgensen LH, Varhaug JE, Bjøro T.

Thyroid. 2016 Sep;26(9):1225-38. doi: 10.1089/thy.2015.0673. Epub 2016 Aug 11.

PMID:
27400880
28.
29.
30.

Development of a prosaposin-derived therapeutic cyclic peptide that targets ovarian cancer via the tumor microenvironment.

Wang S, Blois A, El Rayes T, Liu JF, Hirsch MS, Gravdal K, Palakurthi S, Bielenberg DR, Akslen LA, Drapkin R, Mittal V, Watnick RS.

Sci Transl Med. 2016 Mar 9;8(329):329ra34. doi: 10.1126/scitranslmed.aad5653.

PMID:
26962158
31.

Evaluation of Tumor Cell Proliferation by Ki-67 Expression and Mitotic Count in Lymph Node Metastases from Breast Cancer.

Aziz S, Wik E, Knutsvik G, Klingen TA, Chen Y, Davidsen B, Aas H, Aas T, Akslen LA.

PLoS One. 2016 Mar 8;11(3):e0150979. doi: 10.1371/journal.pone.0150979. eCollection 2016.

32.

BRAF-V600E expression in primary nodular melanoma is associated with aggressive tumour features and reduced survival.

Hugdahl E, Kalvenes MB, Puntervoll HE, Ladstein RG, Akslen LA.

Br J Cancer. 2016 Mar 29;114(7):801-8. doi: 10.1038/bjc.2016.44. Epub 2016 Feb 25.

33.

Strong Expression of Hypoxia-Inducible Factor-1α (HIF-1α) Is Associated with Axl Expression and Features of Aggressive Tumors in African Breast Cancer.

Nalwoga H, Ahmed L, Arnes JB, Wabinga H, Akslen LA.

PLoS One. 2016 Jan 13;11(1):e0146823. doi: 10.1371/journal.pone.0146823. eCollection 2016.

34.

Pre-diagnostic high-sensitive C-reactive protein and breast cancer risk, recurrence, and survival.

Frydenberg H, Thune I, Lofterød T, Mortensen ES, Eggen AE, Risberg T, Wist EA, Flote VG, Furberg AS, Wilsgaard T, Akslen LA, McTiernan A.

Breast Cancer Res Treat. 2016 Jan;155(2):345-54. doi: 10.1007/s10549-015-3671-1. Epub 2016 Jan 6.

PMID:
26740213
35.

Tumor necrosis is an important hallmark of aggressive endometrial cancer and associates with hypoxia, angiogenesis and inflammation responses.

Bredholt G, Mannelqvist M, Stefansson IM, Birkeland E, Bø TH, Øyan AM, Trovik J, Kalland KH, Jonassen I, Salvesen HB, Wik E, Akslen LA.

Oncotarget. 2015 Nov 24;6(37):39676-91. doi: 10.18632/oncotarget.5344.

36.

Mammographic density and histopathologic characteristics of screen-detected tumors in the Norwegian Breast Cancer Screening Program.

Moshina N, Ursin G, Hoff SR, Akslen LA, Roman M, Sebuødegård S, Hofvind S.

Acta Radiol Open. 2015 Sep 17;4(9):2058460115604340. doi: 10.1177/2058460115604340. eCollection 2015 Sep.

37.

Women treated with breast conserving surgery do better than those with mastectomy independent of detection mode, prognostic and predictive tumor characteristics.

Hofvind S, Holen Å, Aas T, Roman M, Sebuødegård S, Akslen LA.

Eur J Surg Oncol. 2015 Oct;41(10):1417-22. doi: 10.1016/j.ejso.2015.07.002. Epub 2015 Jul 17.

PMID:
26253193
38.

Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma.

Law MH, Bishop DT, Lee JE, Brossard M, Martin NG, Moses EK, Song F, Barrett JH, Kumar R, Easton DF, Pharoah PDP, Swerdlow AJ, Kypreou KP, Taylor JC, Harland M, Randerson-Moor J, Akslen LA, Andresen PA, Avril MF, Azizi E, Scarrà GB, Brown KM, Dębniak T, Duffy DL, Elder DE, Fang S, Friedman E, Galan P, Ghiorzo P, Gillanders EM, Goldstein AM, Gruis NA, Hansson J, Helsing P, Hočevar M, Höiom V, Ingvar C, Kanetsky PA, Chen WV; GenoMEL Consortium; Essen-Heidelberg Investigators; SDH Study Group; Q-MEGA and QTWIN Investigators; AMFS Investigators; ATHENS Melanoma Study Group, Landi MT, Lang J, Lathrop GM, Lubiński J, Mackie RM, Mann GJ, Molven A, Montgomery GW, Novaković S, Olsson H, Puig S, Puig-Butille JA, Qureshi AA, Radford-Smith GL, van der Stoep N, van Doorn R, Whiteman DC, Craig JE, Schadendorf D, Simms LA, Burdon KP, Nyholt DR, Pooley KA, Orr N, Stratigos AJ, Cust AE, Ward SV, Hayward NK, Han J, Schulze HJ, Dunning AM, Bishop JAN, Demenais F, Amos CI, MacGregor S, Iles MM.

Nat Genet. 2015 Sep;47(9):987-995. doi: 10.1038/ng.3373. Epub 2015 Aug 3.

39.

Microvascular proliferation in luminal A and basal-like breast cancer subtypes.

Kraby MR, Krüger K, Opdahl S, Vatten LJ, Akslen LA, Bofin AM.

J Clin Pathol. 2015 Nov;68(11):891-7. doi: 10.1136/jclinpath-2015-203037. Epub 2015 Jul 14.

PMID:
26175265
40.

Increased tumor cell expression of Axl is a marker of aggressive features in breast cancer among African women.

Ahmed L, Nalwoga H, Arnes JB, Wabinga H, Micklem DR, Akslen LA.

APMIS. 2015 Aug;123(8):688-96. doi: 10.1111/apm.12403. Epub 2015 May 25.

PMID:
26011102
41.

Concomitant inactivation of the p53- and pRB- functional pathways predicts resistance to DNA damaging drugs in breast cancer in vivo.

Knappskog S, Berge EO, Chrisanthar R, Geisler S, Staalesen V, Leirvaag B, Yndestad S, de Faveri E, Karlsen BO, Wedge DC, Akslen LA, Lilleng PK, Løkkevik E, Lundgren S, Østenstad B, Risberg T, Mjaaland I, Aas T, Lønning PE.

Mol Oncol. 2015 Oct;9(8):1553-64. doi: 10.1016/j.molonc.2015.04.008. Epub 2015 May 8.

42.

Increased angiogenesis is associated with a 32-gene expression signature and 6p21 amplification in aggressive endometrial cancer.

Stefansson IM, Raeder M, Wik E, Mannelqvist M, Kusonmano K, Knutsvik G, Haldorsen I, Trovik J, Øyan AM, Kalland KH, Staff AC, Salvesen HB, Akslen LA.

Oncotarget. 2015 Apr 30;6(12):10634-45.

43.

Post-PET ultrasound improves specificity of 18F-FDG-PET for recurrent differentiated thyroid cancer while maintaining sensitivity.

Biermann M, Kråkenes J, Brauckhoff K, Haugland HK, Heinecke A, Akslen LA, Varhaug JE, Brauckhoff M.

Acta Radiol. 2015 Nov;56(11):1350-60. doi: 10.1177/0284185115574298. Epub 2015 Mar 13.

44.

A registry-based study of thyroid paraganglioma: histological and genetic characteristics.

von Dobschuetz E, Leijon H, Schalin-Jäntti C, Schiavi F, Brauckhoff M, Peczkowska M, Spiazzi G, Demattè S, Cecchini ME, Sartorato P, Krajewska J, Hasse-Lazar K, Roszkowska-Purska K, Taschin E, Malinoc A, Akslen LA, Arola J, Lange D, Fassina A, Pennelli G, Barbareschi M, Luettges J, Prejbisz A, Januszewicz A, Strate T, Bausch B, Castinetti F, Jarzab B, Opocher G, Eng C, Neumann HP.

Endocr Relat Cancer. 2015 Apr;22(2):191-204. doi: 10.1530/ERC-14-0558. Epub 2015 Jan 16.

45.

Breast cancer stromal elastosis is associated with mammography screening detection, low Ki67 expression and favourable prognosis in a population-based study.

Chen Y, Klingen TA, Wik E, Aas H, Vigeland E, Liestøl K, Garred Ø, Mæhlen J, Akslen LA, Lømo J.

Diagn Pathol. 2014 Dec 19;9:230. doi: 10.1186/s13000-014-0230-8.

46.

Evaluation of Ki67 expression across distinct categories of breast cancer specimens: a population-based study of matched surgical specimens, core needle biopsies and tissue microarrays.

Knutsvik G, Stefansson IM, Aziz S, Arnes J, Eide J, Collett K, Akslen LA.

PLoS One. 2014 Nov 6;9(11):e112121. doi: 10.1371/journal.pone.0112121. eCollection 2014.

47.

Frequencies of KIT and GNAQ mutations in acral melanoma.

Puntervoll HE, Molven A, Akslen LA.

J Cutan Pathol. 2014 Nov;41(11):893-4. doi: 10.1111/cup.12382. Epub 2014 Nov 3. No abstract available.

PMID:
25363280
48.

The effect on melanoma risk of genes previously associated with telomere length.

Iles MM, Bishop DT, Taylor JC, Hayward NK, Brossard M, Cust AE, Dunning AM, Lee JE, Moses EK, Akslen LA; AMFS Investigators, Andresen PA, Avril MF, Azizi E, Scarrà GB, Brown KM, Dębniak T, Elder DE, Friedman E, Ghiorzo P, Gillanders EM, Goldstein AM, Gruis NA, Hansson J, Harland M, Helsing P, Hočevar M, Höiom V; IBD investigators, Ingvar C, Kanetsky PA, Landi MT, Lang J, Lathrop GM, Lubiński J, Mackie RM, Martin NG, Molven A, Montgomery GW, Novaković S, Olsson H, Puig S, Puig-Butille JA; QMEGA and QTWIN Investigators, Radford-Smith GL, Randerson-Moor J; SDH Study Group, van der Stoep N, van Doorn R, Whiteman DC, MacGregor S, Pooley KA, Ward SV, Mann GJ, Amos CI, Pharoah PD, Demenais F, Law MH, Newton Bishop JA, Barrett JH; GenoMEL Consortium.

J Natl Cancer Inst. 2014 Sep 17;106(10). pii: dju267. doi: 10.1093/jnci/dju267. Print 2014 Oct.

49.

Prostate cancer antigen-3 (PCA3) and PCA3-based nomograms in the diagnosis of prostate cancer: an external validation of Hansen's nomogram on a Norwegian cohort.

Nygård Y, Haukaas SA, Eide GE, Halvorsen OJ, Gravdal K, Frugård J, Akslen LA, Beisland C.

Scand J Urol. 2015 Feb;49(1):8-15. doi: 10.3109/21681805.2014.949841. Epub 2014 Aug 20.

PMID:
25141128
50.

Fine mapping of genetic susceptibility loci for melanoma reveals a mixture of single variant and multiple variant regions.

Barrett JH, Taylor JC, Bright C, Harland M, Dunning AM, Akslen LA, Andresen PA, Avril MF, Azizi E, Bianchi Scarrà G, Brossard M, Brown KM, Dębniak T, Elder DE, Friedman E, Ghiorzo P, Gillanders EM, Gruis NA, Hansson J, Helsing P, Hočevar M, Höiom V, Ingvar C, Landi MT, Lang J, Lathrop GM, Lubiński J, Mackie RM, Molven A, Novaković S, Olsson H, Puig S, Puig-Butille JA, van der Stoep N, van Doorn R, van Workum W, Goldstein AM, Kanetsky PA, Pharoah PD, Demenais F, Hayward NK, Newton Bishop JA, Bishop DT, Iles MM; GenoMEL Consortium.

Int J Cancer. 2015 Mar 15;136(6):1351-60. doi: 10.1002/ijc.29099. Epub 2014 Aug 14.

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