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Items: 6

1.

Interaction of the N terminus of ADP-ribosylation factor with the PH domain of the GTPase-activating protein ASAP1 requires phosphatidylinositol 4,5-bisphosphate.

Roy NS, Jian X, Soubias O, Zhai P, Hall JR, Dagher JN, Coussens NP, Jenkins LM, Luo R, Akpan IO, Hall MD, Byrd RA, Yohe ME, Randazzo PA.

J Biol Chem. 2019 Oct 6. pii: jbc.RA119.009269. doi: 10.1074/jbc.RA119.009269. [Epub ahead of print]

2.

Intensity and duration of TCR signaling is limited by p38 phosphorylation of ZAP-70T293 and destabilization of the signalosome.

Giardino Torchia ML, Dutta D, Mittelstadt PR, Guha J, Gaida MM, Fish K, Barr VA, Akpan IO, Samelson LE, Tagad HD, Debnath S, Miller Jenkins LM, Appella E, Ashwell JD.

Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):2174-2179. doi: 10.1073/pnas.1713301115. Epub 2018 Feb 12.

3.

The ability of Sos1 to oligomerize the adaptor protein LAT is separable from its guanine nucleotide exchange activity in vivo.

Kortum RL, Balagopalan L, Alexander CP, Garcia J, Pinski JM, Merrill RK, Nguyen PH, Li W, Agarwal I, Akpan IO, Sommers CL, Samelson LE.

Sci Signal. 2013 Nov 12;6(301):ra99. doi: 10.1126/scisignal.2004494.

4.

GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.

Luo R, Akpan IO, Hayashi R, Sramko M, Barr V, Shiba Y, Randazzo PA.

J Biol Chem. 2012 May 18;287(21):17176-85. doi: 10.1074/jbc.M111.334458. Epub 2012 Mar 27.

5.

Elemental analysis of limestone samples from Obajana and Mfamosing limestone deposits, Nigeria, using nuclear techniques.

Akpan IO, Amodu AE, Akpan AE.

Appl Radiat Isot. 2011 Oct;69(10):1355-8. doi: 10.1016/j.apradiso.2011.03.038. Epub 2011 Mar 31.

PMID:
21612938
6.

Enhanced T-cell signaling in cells bearing linker for activation of T-cell (LAT) molecules resistant to ubiquitylation.

Balagopalan L, Ashwell BA, Bernot KM, Akpan IO, Quasba N, Barr VA, Samelson LE.

Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2885-90. doi: 10.1073/pnas.1007098108. Epub 2011 Jan 31.

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