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IL-6 Impairs Vaccine Responses in Neonatal Mice.

Yang J, Sakai J, Siddiqui S, Lee RC, Ireland DDC, Verthelyi D, Akkoyunlu M.

Front Immunol. 2018 Dec 20;9:3049. doi: 10.3389/fimmu.2018.03049. eCollection 2018.


Asbestos-related Diseases in Turkey: Caused Not Only by Naturally Occurring Fibers but Also by Industrial Exposures.

Bayram M, Özkan D, Hayat E, Bilgin M, Mehdi E, Bilgin Ş, Akkoyunlu ME, Okyaltırık F, Kansu A.

Am J Respir Crit Care Med. 2019 Mar 1;199(5):656-659. doi: 10.1164/rccm.201810-1922LE. No abstract available.


TACI Contributes to Plasmodium yoelii Host Resistance by Controlling T Follicular Helper Cell Response and Germinal Center Formation.

Parra M, Yang J, Weitner M, Derrick S, Yang A, Schmidt T, Singh B, Moreno A, Akkoyunlu M.

Front Immunol. 2018 Nov 9;9:2612. doi: 10.3389/fimmu.2018.02612. eCollection 2018.


The Effect of T'ai Chi and Qigong Training on Patients with Obstructive Sleep Apnea: A Randomized Controlled Study.

Yilmaz Gokmen G, Akkoyunlu ME, Kilic L, Algun C.

J Altern Complement Med. 2019 Mar;25(3):317-325. doi: 10.1089/acm.2018.0197. Epub 2018 Nov 14.


TACI-Deficient Macrophages Protect Mice Against Metaflammation and Obesity-Induced Dysregulation of Glucose Homeostasis.

Liu L, Inouye KE, Allman WR, Coleman AS, Siddiqui S, Hotamisligil GS, Akkoyunlu M.

Diabetes. 2018 Aug;67(8):1589-1603. doi: 10.2337/db17-1089. Epub 2018 Jun 5.


Delayed onset of autoreactive antibody production and M2-skewed macrophages contribute to improved survival of TACI deficient MRL-Fas/Lpr mouse.

Liu L, Allman WR, Coleman AS, Takeda K, Lin TL, Akkoyunlu M.

Sci Rep. 2018 Jan 22;8(1):1308. doi: 10.1038/s41598-018-19827-8.


Macrophages-common culprit in obesity and asthma.

Sharma N, Akkoyunlu M, Rabin RL.

Allergy. 2018 Jun;73(6):1196-1205. doi: 10.1111/all.13369. Epub 2017 Dec 27. Review.


The Role of BAFF System Molecules in Host Response to Pathogens.

Sakai J, Akkoyunlu M.

Clin Microbiol Rev. 2017 Oct;30(4):991-1014. doi: 10.1128/CMR.00046-17. Review.


Assignment of Opsonic Values to Pneumococcal Reference Serum 007sp for Use in Opsonophagocytic Assays for 13 Serotypes.

Burton RL, Antonello J, Cooper D, Goldblatt D, Kim KH, Plikaytis BD, Roalfe L, Wauters D, Williams F, Xie GL, Nahm MH, Akkoyunlu M.

Clin Vaccine Immunol. 2017 Feb 6;24(2). pii: e00457-16. doi: 10.1128/CVI.00457-16. Print 2017 Feb.


Distinct Mechanisms Underlie Boosted Polysaccharide-Specific IgG Responses Following Secondary Challenge with Intact Gram-Negative versus Gram-Positive Extracellular Bacteria.

Kar S, Arjunaraja S, Akkoyunlu M, Pier GB, Snapper CM.

J Immunol. 2016 Jun 1;196(11):4614-21. doi: 10.4049/jimmunol.1600082. Epub 2016 Apr 22.


MRL Strains Have a BAFFR Mutation without Functional Consequence.

Allman WR, Liu L, Coleman AS, Akkoyunlu M.

PLoS One. 2016 May 5;11(5):e0154518. doi: 10.1371/journal.pone.0154518. eCollection 2016.


Relationship of CTLA4 and CD28 polymorphisms with lung involvement, HRCT findings and pulmonary function tests in Turkish patients with ankylosing spondylitis.

Karakose Okyaltırık F, Rezvani A, Turan S, Uysal Ö, Yakar F, Sozgen H, Ozkan NE, Akkoyunlu ME, Bayram M, Kutbay Ozcelik H, Sezer M, Guler M, Yaylım İ, Kart L.

Clin Respir J. 2017 Sep;11(5):593-601. doi: 10.1111/crj.12388. Epub 2015 Oct 9.


TACI deficiency leads to alternatively activated macrophage phenotype and susceptibility to Leishmania infection.

Allman WR, Dey R, Liu L, Siddiqui S, Coleman AS, Bhattacharya P, Yano M, Uslu K, Takeda K, Nakhasi HL, Akkoyunlu M.

Proc Natl Acad Sci U S A. 2015 Jul 28;112(30):E4094-103. doi: 10.1073/pnas.1421580112. Epub 2015 Jul 13.


BAFF receptor and TACI in B-1b cell maintenance and antibacterial responses.

Dickinson GS, Akkoyunlu M, Bram RJ, Alugupalli KR.

Ann N Y Acad Sci. 2015 Dec;1362:57-67. doi: 10.1111/nyas.12772. Epub 2015 May 11. Review.


Variables determining the development of colistin-associated renal impairment.

Ceylan B, Taniş M, Akkoyunlu ME, Çınar A, Kurt AR, Akkoyunlu Y, Ozkan D, Ozcelik HK, Aslan T, Fincancı M, Vatansever Ş, İdin K, Guler E, Uysal H.

Wien Klin Wochenschr. 2016 Dec;128(Suppl 8):614-619. doi: 10.1007/s00508-015-0773-z. Epub 2015 Apr 28.


Geriatric patients with known acute kidney injury and normal renal function at the time of admittance to the intensive care unit/assessment of RRT requirement and mortality: retrospective case-control study.

Karakose F, Akkoyunlu ME, Erkoc R, Kansu A, Bayram M, Sezer M, Ozcelik H, Kart L.

Wien Klin Wochenschr. 2015 Apr;127(7-8):290-6. doi: 10.1007/s00508-014-0684-4. Epub 2015 Jan 14.


Vaspin and lipocalin-2 levels in severe obsructive sleep apnea.

Kiskac M, Zorlu M, Akkoyunlu ME, Kilic E, Karatoprak C, Cakirca M, Yavuz E, Ardic C, Camli AA, Cikrikcioglu M, Kart L.

J Thorac Dis. 2014 Jun;6(6):720-5. doi: 10.3978/j.issn.2072-1439.2014.06.17.


Microstructural brain changes in acromegaly: quantitative analysis by diffusion tensor imaging.

Kilicarslan R, Ilhan MM, Alkan A, Aralasmak A, Akkoyunlu ME, Kart L, Tasan E.

Br J Radiol. 2014 Jun;87(1038):20130801. doi: 10.1259/bjr.20130801. Epub 2014 Apr 16.


The effect of obesity on brain diffusion alteration in patients with obstructive sleep apnea.

Kilicarslan R, Alkan A, Sharifov R, Akkoyunlu ME, Aralasmak A, Kocer A, Kart L.

ScientificWorldJournal. 2014 Mar 3;2014:768415. doi: 10.1155/2014/768415. eCollection 2014.


Impaired B cell receptor signaling is responsible for reduced TACI expression and function in X-linked immunodeficient mice.

Uslu K, Coleman AS, Allman WR, Katsenelson N, Bram RJ, Alugupalli KR, Akkoyunlu M.

J Immunol. 2014 Apr 15;192(8):3582-95. doi: 10.4049/jimmunol.1203468. Epub 2014 Mar 19.


[The frequency and properties of REM related obstructive sleep apnea among the patients with mild related obstructive sleep apnea].

Kutbay Özçelik H, Akkoyunlu ME, Bostanlı P, Bayram M, Atahan E, Sezer M, Karaköse F, Kart L.

Tuberk Toraks. 2013;61(4):283-7. Turkish.


COPD: an underdiagnosed disease at hospital environment.

Kart L, Akkoyunlu ME, Bayram M, Yakar F, Kutbay Özçelik H, Karaköse F, Sezer M.

Wien Klin Wochenschr. 2014 Feb;126(3-4):73-8. doi: 10.1007/s00508-013-0458-4. Epub 2013 Nov 19.


Serum biomarkers in patients with mesothelioma and pleural plaques and healthy subjects exposed to naturally occurring asbestos.

Bayram M, Dongel I, Akbaş A, Benli I, Akkoyunlu ME, Bakan ND.

Lung. 2014 Feb;192(1):197-203. doi: 10.1007/s00408-013-9526-9. Epub 2013 Oct 30.


Does hormonal control obviate positive airway pressure therapy in acromegaly with sleep-disordered breathing?

Akkoyunlu ME, Ilhan MM, Bayram M, Taşan E, Yakar F, Ozçelik HK, Karakose F, Kart L.

Respir Med. 2013 Nov;107(11):1803-9. doi: 10.1016/j.rmed.2013.08.043. Epub 2013 Sep 11.


MR spectroscopy features of brain in patients with mild and severe obstructive sleep apnea syndrome.

Alkan A, Sharifov R, Akkoyunlu ME, Kiliçarslan R, Toprak H, Aralasmak A, Kart L.

Clin Imaging. 2013 Nov-Dec;37(6):989-92. doi: 10.1016/j.clinimag.2013.07.010. Epub 2013 Aug 30.


Intense FDG uptake on PET/CT in the upper and lower respiratory system indicative of Wegener's granulomatosis.

Aydin M, Akkoyunlu ME, Yakar F, Ergul N, Sezer M.

Rev Esp Med Nucl Imagen Mol. 2014 Jan-Feb;33(1):32-5. doi: 10.1016/j.remn.2013.03.003. Epub 2013 May 14.


[Relationship between symptoms of obstructive sleep apnea syndrome and traffic accidents in the city drivers].

Akkoyunlu ME, Kart L, Uludağ M, Bayram M, Alisha G, Özçelik H, Karaköse F, Sezer M.

Tuberk Toraks. 2013;61(1):33-7. Turkish.


Investigation of obstructive sleep apnoea syndrome prevalence among long-distance drivers from Zonguldak, Turkey.

Akkoyunlu ME, Altın R, Kart L, Atalay F, Ornek T, Bayram M, Tor M.

Multidiscip Respir Med. 2013 Feb 6;8(1):10. doi: 10.1186/2049-6958-8-10.


Pott abscess mimicking aortic aneurysm in chest X-ray.

Akkoyunlu Y, Aslan T, Akkoyunlu ME.

Braz J Infect Dis. 2013 Jan-Feb;17(1):106-7. doi: 10.1016/j.bjid.2012.06.028. Epub 2013 Jan 16. No abstract available.


Bacterial polysaccharide-mediated downregulation of TACI and B-cell apoptosis contribute to the hyporesponsiveness against bacterial polysaccharides vaccines.

Coleman AS, Akkoyunlu M.

J Infect Dis. 2013 Mar 1;207(5):872-3. doi: 10.1093/infdis/jis770. Epub 2012 Dec 13. No abstract available.


The effect of sleep apnea syndrome on the development of diabetic nephropathy in patients with type 2 diabetes.

Buyukaydin B, Akkoyunlu ME, Kazancioglu R, Karakose F, Ozcelik HK, Erkoc R, Kart L.

Diabetes Res Clin Pract. 2012 Oct;98(1):140-3. doi: 10.1016/j.diabres.2012.07.007. Epub 2012 Aug 18.


Absolute blood eosinophil count and 1-year mortality risk following hospitalization with acute heart failure.

Cikrikcioglu MA, Soysal P, Dikerdem D, Cakirca M, Kazancioglu R, Yolbas S, Erkal H, Hursitoglu M, Karakose TK, Kiskac M, Akkaya M, Zorlu M, Akkoyunlu ME, Tukek T.

Eur J Emerg Med. 2012 Aug;19(4):257-63. doi: 10.1097/MEJ.0b013e32834c67eb.


TACI expression is low both in human and mouse newborns.

Akkoyunlu M.

Scand J Immunol. 2012 Mar;75(3):368. doi: 10.1111/j.1365-3083.2011.02651.x. No abstract available.


Establishment of a new human pneumococcal standard reference serum, 007sp.

Goldblatt D, Plikaytis BD, Akkoyunlu M, Antonello J, Ashton L, Blake M, Burton R, Care R, Durant N, Feavers I, Fernsten P, Fievet F, Giardina P, Jansen K, Katz L, Kierstead L, Lee L, Lin J, Maisonneuve J, Nahm MH, Raab J, Romero-Steiner S, Rose C, Schmidt D, Stapleton J, Carlone GM.

Clin Vaccine Immunol. 2011 Oct;18(10):1728-36. doi: 10.1128/CVI.05252-11. Epub 2011 Aug 18.


A host-restricted viral vector for antigen-specific immunization against Lyme disease pathogen.

Xiao S, Kumar M, Yang X, Akkoyunlu M, Collins PL, Samal SK, Pal U.

Vaccine. 2011 Jul 18;29(32):5294-303. doi: 10.1016/j.vaccine.2011.05.010. Epub 2011 May 19.


The results of computed tomography guided tru-cut transthoracic biopsy: complications and related risk factors.

Beşir FH, Altın R, Kart L, Akkoyunlu M, Ozdemir H, Ornek T, Gündoğdu S.

Wien Klin Wochenschr. 2011 Feb;123(3-4):79-82. doi: 10.1007/s00508-011-1538-y. Epub 2011 Feb 17.


Detection of naturally occurring antibodies against Protein D of Haemophilus influenzae.

Akkoyunlu M.

Vaccine. 2011 Apr 5;29(16):2834; author reply 2835. doi: 10.1016/j.vaccine.2011.01.073. Epub 2011 Feb 1. No abstract available.


Suppressive effect of bacterial polysaccharides on BAFF system is responsible for their poor immunogenicity.

Kanswal S, Katsenelson N, Allman W, Uslu K, Blake MS, Akkoyunlu M.

J Immunol. 2011 Feb 15;186(4):2430-43. doi: 10.4049/jimmunol.1002976. Epub 2011 Jan 19.


Evaluation of vascular reactivity of young male hypogonadotrophic hypogonadism patients.

Deniz F, Ermiş N, Kepez A, Türk B, Akkoyunlu M, Kara B, Kutlu M.

Int J Cardiovasc Imaging. 2010 Jan;26(1):35-40. doi: 10.1007/s10554-009-9505-7. Epub 2009 Sep 12.


Deficient TACI expression on B lymphocytes of newborn mice leads to defective Ig secretion in response to BAFF or APRIL.

Kanswal S, Katsenelson N, Selvapandiyan A, Bram RJ, Akkoyunlu M.

J Immunol. 2008 Jul 15;181(2):976-90. Erratum in: J Immunol. 2008 Oct 1;181(7):5174.


Prediction of premature atherosclerosis by endothelial dysfunction and increased intima-media thickness in glycogen storage disease types Ia and III.

Yekeler E, Dursun M, Emeksiz E, Akkoyunlu M, Akyol Y, Demir F, Gökcay G, Demirkol M.

Turk J Pediatr. 2007 Apr-Jun;49(2):115-9.


Synthetic CpG oligodeoxynucleotides augment BAFF- and APRIL-mediated immunoglobulin secretion.

Katsenelson N, Kanswal S, Puig M, Mostowski H, Verthelyi D, Akkoyunlu M.

Eur J Immunol. 2007 Jul;37(7):1785-95.


Neisseria meningitidis type C capsular polysaccharide inhibits lipooligosaccharide-induced cell activation by binding to CD14.

Kocabas C, Katsenelson N, Kanswal S, Kennedy MN, Cui X, Blake MS, Segal DM, Akkoyunlu M.

Cell Microbiol. 2007 May;9(5):1297-310. Epub 2007 Jan 22.


Interferon-gamma deficiency reveals that 129Sv mice are inherently more susceptible to Anaplasma phagocytophilum than C57BL/6 mice.

Wang T, Akkoyunlu M, Banerjee R, Fikrig E.

FEMS Immunol Med Microbiol. 2004 Nov 1;42(3):299-305.


Murine neutrophils require alpha1,3-fucosylation but not PSGL-1 for productive infection with Anaplasma phagocytophilum.

Carlyon JA, Akkoyunlu M, Xia L, Yago T, Wang T, Cummings RD, McEver RP, Fikrig E.

Blood. 2003 Nov 1;102(9):3387-95. Epub 2003 Jul 17.


Structurally distinct requirements for binding of P-selectin glycoprotein ligand-1 and sialyl Lewis x to Anaplasma phagocytophilum and P-selectin.

Yago T, Leppänen A, Carlyon JA, Akkoyunlu M, Karmakar S, Fikrig E, Cummings RD, McEver RP.

J Biol Chem. 2003 Sep 26;278(39):37987-97. Epub 2003 Jul 7.


Superoxide anion production during Anaplasma phagocytophila infection.

Wang T, Malawista SE, Pal U, Grey M, Meek J, Akkoyunlu M, Thomas V, Fikrig E.

J Infect Dis. 2002 Jul 15;186(2):274-80. Epub 2002 Jul 3.


Renal Behçet's disease: a cumulative analysis.

Akpolat T, Akkoyunlu M, Akpolat I, Dilek M, Odabas AR, Ozen S.

Semin Arthritis Rheum. 2002 Apr;31(5):317-37. Review.


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