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Items: 1 to 50 of 328

1.

Quantitative analysis reveals reciprocal regulations underlying recovery dynamics of thymocytes and thymic environment in mice.

Kaneko KB, Tateishi R, Miyao T, Takakura Y, Akiyama N, Yokota R, Akiyama T, Kobayashi TJ.

Commun Biol. 2019 Nov 29;2:444. doi: 10.1038/s42003-019-0688-8. eCollection 2019.

PMID:
31815199
2.

Effect of rifampicin and clarithromycin on the CYP3A activity in patients with Mycobacterium avium complex.

Akiyama N, Inui N, Mori K, Nakamura Y, Hayakawa H, Tanaka S, Uchida S, Namiki N, Watanabe H, Suda T.

J Thorac Dis. 2019 Sep;11(9):3814-3821. doi: 10.21037/jtd.2019.09.06.

3.

Keratinocyte growth factor (KGF) induces stem/progenitor cell growth in middle ear mucosa.

Yamamoto-Fukuda T, Akiyama N, Kojima H.

Int J Pediatr Otorhinolaryngol. 2019 Oct 4;128:109699. doi: 10.1016/j.ijporl.2019.109699. [Epub ahead of print]

PMID:
31614241
4.

Efficacy of Brazilian Propolis Supplementation for Japanese Lactating Women for Atopic Sensitization and Nonspecific Symptoms in Their Offspring: A Randomized, Double-Blind, Placebo-Controlled Trial.

Igarashi G, Segawa T, Akiyama N, Nishino T, Ito T, Tachimoto H, Urashima M.

Evid Based Complement Alternat Med. 2019 Sep 11;2019:8647205. doi: 10.1155/2019/8647205. eCollection 2019.

5.

Clinical significance of serum S100 calcium-binding protein A4 in idiopathic pulmonary fibrosis.

Akiyama N, Hozumi H, Isayama T, Okada J, Sugiura K, Yasui H, Suzuki Y, Kono M, Karayama M, Furuhashi K, Enomoto N, Fujisawa T, Inui N, Nakamura Y, Suda T.

Respirology. 2019 Oct 9. doi: 10.1111/resp.13707. [Epub ahead of print]

PMID:
31597225
6.

Disseminated thymic B-cell lymphoma in a Holstein heifer.

Hishamnuri WNAD, Nakagun S, Maezawa M, Sakaguchi K, Akiyama N, Watanabe KI, Horiuchi N, Kobayashi Y, Inokuma H.

J Vet Diagn Invest. 2019 Nov;31(6):852-855. doi: 10.1177/1040638719875501. Epub 2019 Sep 24.

PMID:
31551023
7.

Clinical Features of Febrile Urinary Tract Infection Caused by Extended-spectrum Beta-lactamase-producing Escherichia Coli in Children.

Ohnishi T, Mishima Y, Takizawa S, Tsutsumi K, Amemiya A, Akiyama N, Kanna Y, Asato S, Tomita M, Ikemiyagi M, Shikoro N, Nakazawa M, Kurihara N, Kamimaki I.

Keio J Med. 2019 Aug 30. doi: 10.2302/kjm.2019-0005-OA. [Epub ahead of print]

8.

YES1 Is a Targetable Oncogene in Cancers Harboring YES1 Gene Amplification.

Hamanaka N, Nakanishi Y, Mizuno T, Horiguchi-Takei K, Akiyama N, Tanimura H, Hasegawa M, Satoh Y, Tachibana Y, Fujii T, Sakata K, Ogasawara K, Ebiike H, Koyano H, Sato H, Ishii N, Mio T.

Cancer Res. 2019 Nov 15;79(22):5734-5745. doi: 10.1158/0008-5472.CAN-18-3376. Epub 2019 Aug 7.

PMID:
31391186
9.

Partial Epithelial-Mesenchymal Transition Was Observed Under p63 Expression in Acquired Middle Ear Cholesteatoma and Congenital Cholesteatoma.

Takahashi M, Yamamoto-Fukuda T, Akiyama N, Motegi M, Yamamoto K, Tanaka Y, Yamamoto Y, Kojima H.

Otol Neurotol. 2019 Sep;40(8):e803-e811. doi: 10.1097/MAO.0000000000002328.

PMID:
31348131
10.

Biochemical characterization of archaeal homocitrate synthase from SulfolobusĀ acidocaldarius.

Suzuki T, Akiyama N, Yoshida A, Tomita T, Lassak K, Haurat MF, Okada T, Takahashi K, Albers SV, Kuzuyama T, Nishiyama M.

FEBS Lett. 2019 Jul 22. doi: 10.1002/1873-3468.13550. [Epub ahead of print]

PMID:
31330039
11.

Regulation of DNA methylation levels in the process of oral mucosal regeneration in a rat oral ulcer model.

Akiyama N, Yamamoto-Fukuda T, Yoshikawa M, Kojima H.

Histol Histopathol. 2019 Jul 9:18147. doi: 10.14670/HH-18-147. [Epub ahead of print]

PMID:
31286466
12.

Pleiotropic Effects of ebony and tan on Pigmentation and Cuticular Hydrocarbon Composition in Drosophila melanogaster.

Massey JH, Akiyama N, Bien T, Dreisewerd K, Wittkopp PJ, Yew JY, Takahashi A.

Front Physiol. 2019 May 1;10:518. doi: 10.3389/fphys.2019.00518. eCollection 2019.

13.

Down-regulation of GATA1-dependent erythrocyte-related genes in the spleens of mice exposed to a space travel.

Horie K, Sasanuma H, Kudo T, Fujita SI, Miyauchi M, Miyao T, Seki T, Akiyama N, Takakura Y, Shimbo M, Jeon H, Shirakawa M, Shiba D, Yoshida N, Muratani M, Takahashi S, Akiyama T.

Sci Rep. 2019 May 21;9(1):7654. doi: 10.1038/s41598-019-44067-9.

14.

Anaplastic ependymoma arising from the lower segment of the uterine corpus: Case report and literature review.

Akiyama N, Tanaka H, Izawa M, Asakura T, Taniguchi H, Mikami Y.

J Obstet Gynaecol Res. 2019 Jul;45(7):1418-1422. doi: 10.1111/jog.13984. Epub 2019 May 6.

PMID:
31060102
15.

Switch maintenance therapy with S-1 after induction therapy with carboplatin and nanoparticle albumin-bound paclitaxel in advanced lung squamous cell carcinoma.

Akiyama N, Karayama M, Inui N, Yasui H, Hozumi H, Suzuki Y, Furuhashi K, Fujisawa T, Enomoto N, Nakamura Y, Inami N, Matsuura S, Kaida Y, Uto T, Matsui T, Asada K, Matsuda H, Fujii M, Toyoshima M, Suda T.

Invest New Drugs. 2019 Jun;37(3):531-537. doi: 10.1007/s10637-019-00747-x. Epub 2019 Feb 21.

PMID:
30790149
16.

Effects of dietary protein contents and habitual endurance exercise on supplemental leucine oxidation in mice.

Taniguchi H, Akiyama N, Ishihara K.

Biosci Biotechnol Biochem. 2019 Apr;83(4):728-737. doi: 10.1080/09168451.2018.1559026. Epub 2018 Dec 24.

PMID:
30582438
17.

[A Cost-effectiveness Analysis of Sunitinib vs. Interferon-alpha in Patient with Advanced Renal Cell Carcinoma in Japan].

Tomura K, Naito Y, Sunaga T, Kurihara T, Usuda M, Nagatani A, Ogawa Y, Akiyama N, Sasaki H, Murata T, Sakamaki H, Kogo M, Sasaki T.

Yakugaku Zasshi. 2018;138(11):1397-1407. doi: 10.1248/yakushi.17-00189. Japanese.

18.

Involvement of interleukin-31 receptor A in morphine-induced itching and antinociception in mice.

Tsuji M, Arai I, Miyagawa K, Miyagishi H, Saito A, Takeda K, Takeda H, Akiyama N, Saito S.

Eur J Pain. 2019 Feb;23(2):378-388. doi: 10.1002/ejp.1312. Epub 2018 Sep 21.

PMID:
30176108
19.

Acquired JHDM1D-BRAF Fusion Confers Resistance to FGFR Inhibition in FGFR2-Amplified Gastric Cancer.

Sase H, Nakanishi Y, Aida S, Horiguchi-Takei K, Akiyama N, Fujii T, Sakata K, Mio T, Aoki M, Ishii N.

Mol Cancer Ther. 2018 Oct;17(10):2217-2225. doi: 10.1158/1535-7163.MCT-17-1022. Epub 2018 Jul 25.

20.

Infectious complications in adults undergoing intensive chemotherapy for acute myeloid leukemia in 2001-2005 using the Japan Adult Leukemia Study Group AML201 protocols.

Kato H, Fujita H, Akiyama N, Kimura SI, Hiramoto N, Hosono N, Takahashi T, Shigeno K, Minamiguchi H, Miyatake J, Handa H, Kanda Y, Yoshida M, Miyawaki S, Ohtake S, Naoe T, Kiyoi H, Matsumura I, Miyazaki Y; Japan Adult Leukemia Study Group.

Support Care Cancer. 2018 Dec;26(12):4187-4198. doi: 10.1007/s00520-018-4292-0. Epub 2018 Jun 2.

PMID:
29860713
21.

Improved cardiometabolic risk factors in Japanese patients with type 2 diabetes treated with ipragliflozin: a pooled analysis of six randomized, placebo-controlled trials.

Kashiwagi A, Sakatani T, Nakamura I, Akiyama N, Kazuta K, Ueyama E, Takahashi H, Kosakai Y.

Endocr J. 2018 Jul 28;65(7):693-705. doi: 10.1507/endocrj.EJ17-0491. Epub 2018 May 29.

22.

Healthcare costs for the elderly in Japan: Analysis of medical care and long-term care claim records.

Akiyama N, Shiroiwa T, Fukuda T, Murashima S, Hayashida K.

PLoS One. 2018 May 14;13(5):e0190392. doi: 10.1371/journal.pone.0190392. eCollection 2018.

23.

Long-term hindlimb unloading causes a preferential reduction of medullary thymic epithelial cells expressing autoimmune regulator (Aire).

Horie K, Kudo T, Yoshinaga R, Akiyama N, Sasanuma H, Kobayashi TJ, Shimbo M, Jeon H, Miyao T, Miyauchi M, Shirakawa M, Shiba D, Yoshida N, Muratani M, Takahashi S, Akiyama T.

Biochem Biophys Res Commun. 2018 Jun 27;501(3):745-750. doi: 10.1016/j.bbrc.2018.05.060.

PMID:
29753741
24.

Keratinocyte Growth Factor (KGF) Modulates Epidermal Progenitor Cell Kinetics through Activation of p63 in Middle Ear Cholesteatoma.

Yamamoto-Fukuda T, Akiyama N, Takahashi M, Kojima H.

J Assoc Res Otolaryngol. 2018 Jun;19(3):223-241. doi: 10.1007/s10162-018-0662-z. Epub 2018 Mar 16.

25.

Synchronous Duodenal Cancer and Lung Cancer Harboring an Epidermal Growth Factor Receptor Mutation Treated with Erlotinib and Oral Fluoropyrimidine.

Akiyama N, Karayama M, Iwaizumi M, Kusama Y, Kono M, Hozumi H, Suzuki Y, Furuhashi K, Enomoto N, Fujisawa T, Nakamura Y, Inui N, Suda T.

Intern Med. 2017 Sep 1;56(17):2367-2371. doi: 10.2169/internalmedicine.8312-16. Epub 2017 Aug 10.

26.

Evaluation of YAP signaling in a rat tympanic membrane under a continuous negative pressure load and in human middle ear cholesteatoma.

Akiyama N, Yamamoto-Fukuda T, Yoshikawa M, Kojima H.

Acta Otolaryngol. 2017 Nov;137(11):1158-1165. doi: 10.1080/00016489.2017.1351040. Epub 2017 Jul 14.

PMID:
28708445
27.

The role of acylated-ghrelin in the regulation of sucrose intake.

Kouno T, Akiyama N, Ito T, Fujieda K, Nanchi I, Okuda T, Notoya M, Iwasaki T, Yukioka H.

Endocr J. 2017;64(Suppl.):S21-S23. doi: 10.1507/endocrj.64.S21.

28.

Management of infection during chemotherapy for acute leukemia in Japan: a nationwide questionnaire-based survey by the Japan Adult Leukemia Study Group.

Kimura SI, Fujita H, Kato H, Hiramoto N, Hosono N, Takahashi T, Shigeno K, Hatsumi N, Minamiguchi H, Miyatake J, Handa H, Akiyama N, Kanda Y, Yoshida M, Kiyoi H, Miyazaki Y, Naoe T; Japan Adult Leukemia Study Group (JALSG).

Support Care Cancer. 2017 Nov;25(11):3515-3521. doi: 10.1007/s00520-017-3775-8. Epub 2017 Jun 6.

PMID:
28584934
29.

Regulation of Th2 responses by different cell types expressing the interleukin-31 receptor.

Saito S, Aoki A, Arai I, Takaishi S, Ito H, Akiyama N, Kiyonari H.

Allergy Asthma Clin Immunol. 2017 Apr 17;13:23. doi: 10.1186/s13223-017-0194-9. eCollection 2017.

30.

Programmed death-ligand 1 and its soluble form are highly expressed in nasal natural killer/T-cell lymphoma: a potential rationale for immunotherapy.

Nagato T, Ohkuri T, Ohara K, Hirata Y, Kishibe K, Komabayashi Y, Ueda S, Takahara M, Kumai T, Ishibashi K, Kosaka A, Aoki N, Oikawa K, Uno Y, Akiyama N, Sado M, Takei H, Celis E, Harabuchi Y, Kobayashi H.

Cancer Immunol Immunother. 2017 Jul;66(7):877-890. doi: 10.1007/s00262-017-1987-x. Epub 2017 Mar 27.

PMID:
28349165
31.

Rapid Radiologic Progression of Silicosis.

Tsuchiya K, Toyoshima M, Akiyama N, Kono M, Nakamura Y, Funai K, Baba S, Sugimura H, Kanayama H, Suda T.

Am J Respir Crit Care Med. 2017 May 15;195(10):e39-e42. doi: 10.1164/rccm.201606-1194IM. No abstract available.

PMID:
28339287
32.

The effects of early treatment with anti-venom on length of hospital stay: Analysis of 46 cases of mamushi bites.

Noda K, Akiyama N, I S.

Chudoku Kenkyu. 2017 Mar;30(1):25-30. English, Japanese.

PMID:
30549924
33.

Chronic hyperinsulinemia contributes to insulin resistance under dietary restriction in association with altered lipid metabolism in Zucker diabetic fatty rats.

Morita I, Tanimoto K, Akiyama N, Naya N, Fujieda K, Iwasaki T, Yukioka H.

Am J Physiol Endocrinol Metab. 2017 Apr 1;312(4):E264-E272. doi: 10.1152/ajpendo.00342.2016. Epub 2017 Jan 31.

34.

Discovery of [5-Amino-1-(2-methyl-3H-benzimidazol-5-yl)pyrazol-4-yl]-(1H-indol-2-yl)methanone (CH5183284/Debio 1347), An Orally Available and Selective Fibroblast Growth Factor Receptor (FGFR) Inhibitor.

Ebiike H, Taka N, Matsushita M, Ohmori M, Takami K, Hyohdoh I, Kohchi M, Hayase T, Nishii H, Morikami K, Nakanishi Y, Akiyama N, Shindoh H, Ishii N, Isobe T, Matsuoka H.

J Med Chem. 2016 Dec 8;59(23):10586-10600. Epub 2016 Nov 29.

PMID:
27933954
35.

Reduced intake of carbohydrate prevents the development of obesity and impaired glucose metabolism in ghrelin O-acyltransferase knockout mice.

Kouno T, Akiyama N, Fujieda K, Nanchi I, Okuda T, Iwasaki T, Oka S, Yukioka H.

Peptides. 2016 Dec;86:145-152. doi: 10.1016/j.peptides.2016.11.003. Epub 2016 Nov 2.

PMID:
27816752
36.

Characterization of two Ī²-decarboxylating dehydrogenases from Sulfolobus acidocaldarius.

Takahashi K, Nakanishi F, Tomita T, Akiyama N, Lassak K, Albers SV, Kuzuyama T, Nishiyama M.

Extremophiles. 2016 Nov;20(6):843-853. Epub 2016 Sep 2.

PMID:
27590116
37.

Targeted use of prednisolone with the second IVIG dose for refractory Kawasaki disease.

Kimura M, Harazaki M, Fukuoka T, Asakura I, Sakai H, Kamimaki T, Ohkawara I, Akiyama N, Tsurui S, Iwashima S, Shimomura M, Morishita H, Meguro T, Seto S.

Pediatr Int. 2017 Apr;59(4):397-403. doi: 10.1111/ped.13190. Epub 2016 Dec 19.

PMID:
27743415
38.

Effects of ipragliflozin, a selective sodium-glucose co-transporter 2 inhibitor, on blood pressure in Japanese patients with type 2 diabetes mellitus: a pooled analysis of six randomized, placebo-controlled clinical trials.

Kashiwagi A, Yoshida S, Kawamuki K, Nakamura I, Kazuta K, Ueyama E, Takahashi H, Akiyama N, Kondo Y, Ogihara T.

Diabetol Int. 2016 Sep 9;8(1):76-86. doi: 10.1007/s13340-016-0283-x. eCollection 2017 Mar.

39.

Epigenetic modification augments the immunogenicity of human leukocyte antigen G serving as a tumor antigen for T cell-based immunotherapy.

Ishibashi K, Kumai T, Ohkuri T, Kosaka A, Nagato T, Hirata Y, Ohara K, Oikawa K, Aoki N, Akiyama N, Sado M, Kitada M, Harabuchi Y, Celis E, Kobayashi H.

Oncoimmunology. 2016 Mar 30;5(6):e1169356. doi: 10.1080/2162402X.2016.1169356. eCollection 2016 Jun.

40.

Identification of embryonic precursor cells that differentiate into thymic epithelial cells expressing autoimmune regulator.

Akiyama N, Takizawa N, Miyauchi M, Yanai H, Tateishi R, Shinzawa M, Yoshinaga R, Kurihara M, Demizu Y, Yasuda H, Yagi S, Wu G, Matsumoto M, Sakamoto R, Yoshida N, Penninger JM, Kobayashi Y, Inoue J, Akiyama T.

J Exp Med. 2016 Jul 25;213(8):1441-58. doi: 10.1084/jem.20151780. Epub 2016 Jul 11.

41.

One-dimensional Magnus-type platinum double salts.

Hendon CH, Walsh A, Akiyama N, Konno Y, Kajiwara T, Ito T, Kitagawa H, Sakai K.

Nat Commun. 2016 Jun 20;7:11950. doi: 10.1038/ncomms11950.

42.

Gastrointestinal Bleeding From Duodenal Aberrant Pancreas After Antiangiogenic Therapy.

Nishimoto K, Karayama M, Akiyama N, Suzuki S, Inoue Y, Kono M, Hozumi H, Suzuki Y, Furuhashi K, Enomoto N, Fujisawa T, Nakamura Y, Inui N, Suda T.

J Clin Gastroenterol. 2016 Sep;50(8):689-90. doi: 10.1097/MCG.0000000000000561. No abstract available.

PMID:
27306939
43.

Combined Pulmonary Fibrosis and Emphysema Preceding Lupus Pleuritis.

Kamiya Y, Toyoshima M, Akiyama N, Suda T.

Intern Med. 2016;55(7):783-6. doi: 10.2169/internalmedicine.55.5635. Epub 2016 Apr 1.

44.

Nationwide Survey of the Transfer of Adults With Congenital Heart Disease From Pediatric Cardiology Departments to Adult Congenital Heart Disease Centers in Japan.

Ochiai R, Kato H, Akiyama N, Ichida F, Yao A, Inuzuka R, Niwa K, Shiraishi I, Nakanishi T.

Circ J. 2016 Apr 25;80(5):1242-50. doi: 10.1253/circj.CJ-15-0937. Epub 2016 Mar 31.

45.

Factors underlying natural variation in body pigmentation of Drosophila melanogaster.

Sunaga S, Akiyama N, Miyagi R, Takahashi A.

Genes Genet Syst. 2016 Oct 13;91(2):127-137. Epub 2016 Mar 25.

46.

Improved control of childhood asthma with low-dose, short-term vitamin D supplementation: a randomized, double-blind, placebo-controlled trial.

Tachimoto H, Mezawa H, Segawa T, Akiyama N, Ida H, Urashima M.

Allergy. 2016 Jul;71(7):1001-9. doi: 10.1111/all.12856. Epub 2016 Mar 2.

PMID:
26841365
47.

Ground-based assessment of JAXA mouse habitat cage unit by mouse phenotypic studies.

Shimbo M, Kudo T, Hamada M, Jeon H, Imamura Y, Asano K, Okada R, Tsunakawa Y, Mizuno S, Yagami K, Ishikawa C, Li H, Shiga T, Ishida J, Hamada J, Murata K, Ishimaru T, Hashimoto M, Fukamizu A, Yamane M, Ikawa M, Morita H, Shinohara M, Asahara H, Akiyama T, Akiyama N, Sasanuma H, Yoshida N, Zhou R, Wang YY, Ito T, Kokubu Y, Noguchi TA, Ishimine H, Kurisaki A, Shiba D, Mizuno H, Shirakawa M, Ito N, Takeda S, Takahashi S.

Exp Anim. 2016 May 20;65(2):175-87. doi: 10.1538/expanim.15-0077. Epub 2016 Jan 28.

48.

[THREE CASES OF DRUG-INDUCED PNEUMONIA CAUSED BY MESALAZINE].

Akiyama N, Yokomura K, Nozue T, Abe T, Matsui T, Suda T.

Arerugi. 2015 Dec;64(10):1334-40. doi: 10.15036/arerugi.64.1334. Japanese.

PMID:
26727138
49.

Ghrelin O-acyltransferase knockout mice show resistance to obesity when fed high-sucrose diet.

Kouno T, Akiyama N, Ito T, Okuda T, Nanchi I, Notoya M, Oka S, Yukioka H.

J Endocrinol. 2016 Feb;228(2):115-25. doi: 10.1530/JOE-15-0330. Epub 2015 Dec 8.

PMID:
26645250
50.

Hypergravity Provokes a Temporary Reduction in CD4+CD8+ Thymocyte Number and a Persistent Decrease in Medullary Thymic Epithelial Cell Frequency in Mice.

Tateishi R, Akiyama N, Miyauchi M, Yoshinaga R, Sasanuma H, Kudo T, Shimbo M, Shinohara M, Obata K, Inoue J, Shirakawa M, Shiba D, Asahara H, Yoshida N, Takahashi S, Morita H, Akiyama T.

PLoS One. 2015 Oct 29;10(10):e0141650. doi: 10.1371/journal.pone.0141650. eCollection 2015.

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