Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 314

1.

Switch maintenance therapy with S-1 after induction therapy with carboplatin and nanoparticle albumin-bound paclitaxel in advanced lung squamous cell carcinoma.

Akiyama N, Karayama M, Inui N, Yasui H, Hozumi H, Suzuki Y, Furuhashi K, Fujisawa T, Enomoto N, Nakamura Y, Inami N, Matsuura S, Kaida Y, Uto T, Matsui T, Asada K, Matsuda H, Fujii M, Toyoshima M, Suda T.

Invest New Drugs. 2019 Feb 21. doi: 10.1007/s10637-019-00747-x. [Epub ahead of print]

PMID:
30790149
2.

Effects of dietary protein contents and habitual endurance exercise on supplemental leucine oxidation in mice.

Taniguchi H, Akiyama N, Ishihara K.

Biosci Biotechnol Biochem. 2019 Apr;83(4):728-737. doi: 10.1080/09168451.2018.1559026. Epub 2018 Dec 24.

PMID:
30582438
3.

[A Cost-effectiveness Analysis of Sunitinib vs. Interferon-alpha in Patient with Advanced Renal Cell Carcinoma in Japan].

Tomura K, Naito Y, Sunaga T, Kurihara T, Usuda M, Nagatani A, Ogawa Y, Akiyama N, Sasaki H, Murata T, Sakamaki H, Kogo M, Sasaki T.

Yakugaku Zasshi. 2018;138(11):1397-1407. doi: 10.1248/yakushi.17-00189. Japanese.

4.

Involvement of interleukin-31 receptor A in morphine-induced itching and antinociception in mice.

Tsuji M, Arai I, Miyagawa K, Miyagishi H, Saito A, Takeda K, Takeda H, Akiyama N, Saito S.

Eur J Pain. 2019 Feb;23(2):378-388. doi: 10.1002/ejp.1312. Epub 2018 Sep 21.

PMID:
30176108
5.

Acquired JHDM1D-BRAF Fusion Confers Resistance to FGFR Inhibition in FGFR2-Amplified Gastric Cancer.

Sase H, Nakanishi Y, Aida S, Horiguchi-Takei K, Akiyama N, Fujii T, Sakata K, Mio T, Aoki M, Ishii N.

Mol Cancer Ther. 2018 Oct;17(10):2217-2225. doi: 10.1158/1535-7163.MCT-17-1022. Epub 2018 Jul 25.

PMID:
30045926
6.

Infectious complications in adults undergoing intensive chemotherapy for acute myeloid leukemia in 2001-2005 using the Japan Adult Leukemia Study Group AML201 protocols.

Kato H, Fujita H, Akiyama N, Kimura SI, Hiramoto N, Hosono N, Takahashi T, Shigeno K, Minamiguchi H, Miyatake J, Handa H, Kanda Y, Yoshida M, Miyawaki S, Ohtake S, Naoe T, Kiyoi H, Matsumura I, Miyazaki Y; Japan Adult Leukemia Study Group.

Support Care Cancer. 2018 Dec;26(12):4187-4198. doi: 10.1007/s00520-018-4292-0. Epub 2018 Jun 2.

PMID:
29860713
7.

Improved cardiometabolic risk factors in Japanese patients with type 2 diabetes treated with ipragliflozin: a pooled analysis of six randomized, placebo-controlled trials.

Kashiwagi A, Sakatani T, Nakamura I, Akiyama N, Kazuta K, Ueyama E, Takahashi H, Kosakai Y.

Endocr J. 2018 Jul 28;65(7):693-705. doi: 10.1507/endocrj.EJ17-0491. Epub 2018 May 29.

8.

Healthcare costs for the elderly in Japan: Analysis of medical care and long-term care claim records.

Akiyama N, Shiroiwa T, Fukuda T, Murashima S, Hayashida K.

PLoS One. 2018 May 14;13(5):e0190392. doi: 10.1371/journal.pone.0190392. eCollection 2018.

9.

Long-term hindlimb unloading causes a preferential reduction of medullary thymic epithelial cells expressing autoimmune regulator (Aire).

Horie K, Kudo T, Yoshinaga R, Akiyama N, Sasanuma H, Kobayashi TJ, Shimbo M, Jeon H, Miyao T, Miyauchi M, Shirakawa M, Shiba D, Yoshida N, Muratani M, Takahashi S, Akiyama T.

Biochem Biophys Res Commun. 2018 Jun 27;501(3):745-750. doi: 10.1016/j.bbrc.2018.05.060.

PMID:
29753741
10.

Keratinocyte Growth Factor (KGF) Modulates Epidermal Progenitor Cell Kinetics through Activation of p63 in Middle Ear Cholesteatoma.

Yamamoto-Fukuda T, Akiyama N, Takahashi M, Kojima H.

J Assoc Res Otolaryngol. 2018 Jun;19(3):223-241. doi: 10.1007/s10162-018-0662-z. Epub 2018 Mar 16.

PMID:
29549594
11.

Synchronous Duodenal Cancer and Lung Cancer Harboring an Epidermal Growth Factor Receptor Mutation Treated with Erlotinib and Oral Fluoropyrimidine.

Akiyama N, Karayama M, Iwaizumi M, Kusama Y, Kono M, Hozumi H, Suzuki Y, Furuhashi K, Enomoto N, Fujisawa T, Nakamura Y, Inui N, Suda T.

Intern Med. 2017 Sep 1;56(17):2367-2371. doi: 10.2169/internalmedicine.8312-16. Epub 2017 Aug 10.

12.

Evaluation of YAP signaling in a rat tympanic membrane under a continuous negative pressure load and in human middle ear cholesteatoma.

Akiyama N, Yamamoto-Fukuda T, Yoshikawa M, Kojima H.

Acta Otolaryngol. 2017 Nov;137(11):1158-1165. doi: 10.1080/00016489.2017.1351040. Epub 2017 Jul 14.

PMID:
28708445
13.

The role of acylated-ghrelin in the regulation of sucrose intake.

Kouno T, Akiyama N, Ito T, Fujieda K, Nanchi I, Okuda T, Notoya M, Iwasaki T, Yukioka H.

Endocr J. 2017;64(Suppl.):S21-S23. doi: 10.1507/endocrj.64.S21.

14.

Management of infection during chemotherapy for acute leukemia in Japan: a nationwide questionnaire-based survey by the Japan Adult Leukemia Study Group.

Kimura SI, Fujita H, Kato H, Hiramoto N, Hosono N, Takahashi T, Shigeno K, Hatsumi N, Minamiguchi H, Miyatake J, Handa H, Akiyama N, Kanda Y, Yoshida M, Kiyoi H, Miyazaki Y, Naoe T; Japan Adult Leukemia Study Group (JALSG).

Support Care Cancer. 2017 Nov;25(11):3515-3521. doi: 10.1007/s00520-017-3775-8. Epub 2017 Jun 6.

PMID:
28584934
15.

Regulation of Th2 responses by different cell types expressing the interleukin-31 receptor.

Saito S, Aoki A, Arai I, Takaishi S, Ito H, Akiyama N, Kiyonari H.

Allergy Asthma Clin Immunol. 2017 Apr 17;13:23. doi: 10.1186/s13223-017-0194-9. eCollection 2017.

16.

Programmed death-ligand 1 and its soluble form are highly expressed in nasal natural killer/T-cell lymphoma: a potential rationale for immunotherapy.

Nagato T, Ohkuri T, Ohara K, Hirata Y, Kishibe K, Komabayashi Y, Ueda S, Takahara M, Kumai T, Ishibashi K, Kosaka A, Aoki N, Oikawa K, Uno Y, Akiyama N, Sado M, Takei H, Celis E, Harabuchi Y, Kobayashi H.

Cancer Immunol Immunother. 2017 Jul;66(7):877-890. doi: 10.1007/s00262-017-1987-x. Epub 2017 Mar 27.

PMID:
28349165
17.

Rapid Radiologic Progression of Silicosis.

Tsuchiya K, Toyoshima M, Akiyama N, Kono M, Nakamura Y, Funai K, Baba S, Sugimura H, Kanayama H, Suda T.

Am J Respir Crit Care Med. 2017 May 15;195(10):e39-e42. doi: 10.1164/rccm.201606-1194IM. No abstract available.

PMID:
28339287
18.

The effects of early treatment with anti-venom on length of hospital stay: Analysis of 46 cases of mamushi bites.

Noda K, Akiyama N, I S.

Chudoku Kenkyu. 2017 Mar;30(1):25-30. English, Japanese.

PMID:
30549924
19.

Chronic hyperinsulinemia contributes to insulin resistance under dietary restriction in association with altered lipid metabolism in Zucker diabetic fatty rats.

Morita I, Tanimoto K, Akiyama N, Naya N, Fujieda K, Iwasaki T, Yukioka H.

Am J Physiol Endocrinol Metab. 2017 Apr 1;312(4):E264-E272. doi: 10.1152/ajpendo.00342.2016. Epub 2017 Jan 31.

20.

Discovery of [5-Amino-1-(2-methyl-3H-benzimidazol-5-yl)pyrazol-4-yl]-(1H-indol-2-yl)methanone (CH5183284/Debio 1347), An Orally Available and Selective Fibroblast Growth Factor Receptor (FGFR) Inhibitor.

Ebiike H, Taka N, Matsushita M, Ohmori M, Takami K, Hyohdoh I, Kohchi M, Hayase T, Nishii H, Morikami K, Nakanishi Y, Akiyama N, Shindoh H, Ishii N, Isobe T, Matsuoka H.

J Med Chem. 2016 Dec 8;59(23):10586-10600. Epub 2016 Nov 29.

PMID:
27933954
21.

Reduced intake of carbohydrate prevents the development of obesity and impaired glucose metabolism in ghrelin O-acyltransferase knockout mice.

Kouno T, Akiyama N, Fujieda K, Nanchi I, Okuda T, Iwasaki T, Oka S, Yukioka H.

Peptides. 2016 Dec;86:145-152. doi: 10.1016/j.peptides.2016.11.003. Epub 2016 Nov 2.

PMID:
27816752
22.

Characterization of two β-decarboxylating dehydrogenases from Sulfolobus acidocaldarius.

Takahashi K, Nakanishi F, Tomita T, Akiyama N, Lassak K, Albers SV, Kuzuyama T, Nishiyama M.

Extremophiles. 2016 Nov;20(6):843-853. Epub 2016 Sep 2.

PMID:
27590116
23.

Targeted use of prednisolone with the second IVIG dose for refractory Kawasaki disease.

Kimura M, Harazaki M, Fukuoka T, Asakura I, Sakai H, Kamimaki T, Ohkawara I, Akiyama N, Tsurui S, Iwashima S, Shimomura M, Morishita H, Meguro T, Seto S.

Pediatr Int. 2017 Apr;59(4):397-403. doi: 10.1111/ped.13190. Epub 2016 Dec 19.

PMID:
27743415
24.

Effects of ipragliflozin, a selective sodium-glucose co-transporter 2 inhibitor, on blood pressure in Japanese patients with type 2 diabetes mellitus: a pooled analysis of six randomized, placebo-controlled clinical trials.

Kashiwagi A, Yoshida S, Kawamuki K, Nakamura I, Kazuta K, Ueyama E, Takahashi H, Akiyama N, Kondo Y, Ogihara T.

Diabetol Int. 2016 Sep 9;8(1):76-86. doi: 10.1007/s13340-016-0283-x. eCollection 2017 Mar.

25.

Epigenetic modification augments the immunogenicity of human leukocyte antigen G serving as a tumor antigen for T cell-based immunotherapy.

Ishibashi K, Kumai T, Ohkuri T, Kosaka A, Nagato T, Hirata Y, Ohara K, Oikawa K, Aoki N, Akiyama N, Sado M, Kitada M, Harabuchi Y, Celis E, Kobayashi H.

Oncoimmunology. 2016 Mar 30;5(6):e1169356. doi: 10.1080/2162402X.2016.1169356. eCollection 2016 Jun.

26.

Identification of embryonic precursor cells that differentiate into thymic epithelial cells expressing autoimmune regulator.

Akiyama N, Takizawa N, Miyauchi M, Yanai H, Tateishi R, Shinzawa M, Yoshinaga R, Kurihara M, Demizu Y, Yasuda H, Yagi S, Wu G, Matsumoto M, Sakamoto R, Yoshida N, Penninger JM, Kobayashi Y, Inoue J, Akiyama T.

J Exp Med. 2016 Jul 25;213(8):1441-58. doi: 10.1084/jem.20151780. Epub 2016 Jul 11.

27.

One-dimensional Magnus-type platinum double salts.

Hendon CH, Walsh A, Akiyama N, Konno Y, Kajiwara T, Ito T, Kitagawa H, Sakai K.

Nat Commun. 2016 Jun 20;7:11950. doi: 10.1038/ncomms11950.

28.

Gastrointestinal Bleeding From Duodenal Aberrant Pancreas After Antiangiogenic Therapy.

Nishimoto K, Karayama M, Akiyama N, Suzuki S, Inoue Y, Kono M, Hozumi H, Suzuki Y, Furuhashi K, Enomoto N, Fujisawa T, Nakamura Y, Inui N, Suda T.

J Clin Gastroenterol. 2016 Sep;50(8):689-90. doi: 10.1097/MCG.0000000000000561. No abstract available.

PMID:
27306939
29.

Combined Pulmonary Fibrosis and Emphysema Preceding Lupus Pleuritis.

Kamiya Y, Toyoshima M, Akiyama N, Suda T.

Intern Med. 2016;55(7):783-6. doi: 10.2169/internalmedicine.55.5635. Epub 2016 Apr 1.

30.

Nationwide Survey of the Transfer of Adults With Congenital Heart Disease From Pediatric Cardiology Departments to Adult Congenital Heart Disease Centers in Japan.

Ochiai R, Kato H, Akiyama N, Ichida F, Yao A, Inuzuka R, Niwa K, Shiraishi I, Nakanishi T.

Circ J. 2016 Apr 25;80(5):1242-50. doi: 10.1253/circj.CJ-15-0937. Epub 2016 Mar 31.

31.

Factors underlying natural variation in body pigmentation of Drosophila melanogaster.

Sunaga S, Akiyama N, Miyagi R, Takahashi A.

Genes Genet Syst. 2016 Oct 13;91(2):127-137. Epub 2016 Mar 25.

32.

Improved control of childhood asthma with low-dose, short-term vitamin D supplementation: a randomized, double-blind, placebo-controlled trial.

Tachimoto H, Mezawa H, Segawa T, Akiyama N, Ida H, Urashima M.

Allergy. 2016 Jul;71(7):1001-9. doi: 10.1111/all.12856. Epub 2016 Mar 2.

PMID:
26841365
33.

Ground-based assessment of JAXA mouse habitat cage unit by mouse phenotypic studies.

Shimbo M, Kudo T, Hamada M, Jeon H, Imamura Y, Asano K, Okada R, Tsunakawa Y, Mizuno S, Yagami K, Ishikawa C, Li H, Shiga T, Ishida J, Hamada J, Murata K, Ishimaru T, Hashimoto M, Fukamizu A, Yamane M, Ikawa M, Morita H, Shinohara M, Asahara H, Akiyama T, Akiyama N, Sasanuma H, Yoshida N, Zhou R, Wang YY, Ito T, Kokubu Y, Noguchi TA, Ishimine H, Kurisaki A, Shiba D, Mizuno H, Shirakawa M, Ito N, Takeda S, Takahashi S.

Exp Anim. 2016 May 20;65(2):175-87. doi: 10.1538/expanim.15-0077. Epub 2016 Jan 28.

34.

[THREE CASES OF DRUG-INDUCED PNEUMONIA CAUSED BY MESALAZINE].

Akiyama N, Yokomura K, Nozue T, Abe T, Matsui T, Suda T.

Arerugi. 2015 Dec;64(10):1334-40. doi: 10.15036/arerugi.64.1334. Japanese.

PMID:
26727138
35.

Ghrelin O-acyltransferase knockout mice show resistance to obesity when fed high-sucrose diet.

Kouno T, Akiyama N, Ito T, Okuda T, Nanchi I, Notoya M, Oka S, Yukioka H.

J Endocrinol. 2016 Feb;228(2):115-25. doi: 10.1530/JOE-15-0330. Epub 2015 Dec 8.

PMID:
26645250
36.

Hypergravity Provokes a Temporary Reduction in CD4+CD8+ Thymocyte Number and a Persistent Decrease in Medullary Thymic Epithelial Cell Frequency in Mice.

Tateishi R, Akiyama N, Miyauchi M, Yoshinaga R, Sasanuma H, Kudo T, Shimbo M, Shinohara M, Obata K, Inoue J, Shirakawa M, Shiba D, Asahara H, Yoshida N, Takahashi S, Morita H, Akiyama T.

PLoS One. 2015 Oct 29;10(10):e0141650. doi: 10.1371/journal.pone.0141650. eCollection 2015.

37.

Complex patterns of cis-regulatory polymorphisms in ebony underlie standing pigmentation variation in Drosophila melanogaster.

Miyagi R, Akiyama N, Osada N, Takahashi A.

Mol Ecol. 2015 Dec;24(23):5829-41. doi: 10.1111/mec.13432. Epub 2015 Nov 20.

PMID:
26503353
38.

Positive and Negative Regulatory Mechanisms for Fine-Tuning Cellularity and Functions of Medullary Thymic Epithelial Cells.

Akiyama T, Tateishi R, Akiyama N, Yoshinaga R, Kobayashi TJ.

Front Immunol. 2015 Sep 8;6:461. doi: 10.3389/fimmu.2015.00461. eCollection 2015. Review.

39.

ERK Signal Suppression and Sensitivity to CH5183284/Debio 1347, a Selective FGFR Inhibitor.

Nakanishi Y, Mizuno H, Sase H, Fujii T, Sakata K, Akiyama N, Aoki Y, Aoki M, Ishii N.

Mol Cancer Ther. 2015 Dec;14(12):2831-9. doi: 10.1158/1535-7163.MCT-15-0497. Epub 2015 Oct 5.

40.

Methotrexate-induced Accelerated Pulmonary Nodulosis.

Akiyama N, Toyoshima M, Kono M, Nakamura Y, Funai K, Suda T.

Am J Respir Crit Care Med. 2015 Jul 15;192(2):252-3. doi: 10.1164/rccm.201502-0364IM. No abstract available.

PMID:
26177173
41.

Efficacy and safety of tazobactam/piperacillin as an empirical treatment for the patients of adult and child with febrile neutropenia in Japan.

Tamura K, Akiyama N, Kanda Y, Saito M.

J Infect Chemother. 2015 Sep;21(9):654-62. doi: 10.1016/j.jiac.2015.05.009. Epub 2015 Jun 9.

PMID:
26141812
42.

Visualization of RelB expression and activation at the single-cell level during dendritic cell maturation in Relb-Venus knock-in mice.

Seki T, Yamamoto M, Taguchi Y, Miyauchi M, Akiyama N, Yamaguchi N, Gohda J, Akiyama T, Inoue J.

J Biochem. 2015 Dec;158(6):485-95. doi: 10.1093/jb/mvv064. Epub 2015 Jun 26.

PMID:
26115685
43.

Catalytic subunits of the phosphatase calcineurin interact with NF-κB-inducing kinase (NIK) and attenuate NIK-dependent gene expression.

Shinzawa M, Konno H, Qin J, Akiyama N, Miyauchi M, Ohashi H, Miyamoto-Sato E, Yanagawa H, Akiyama T, Inoue J.

Sci Rep. 2015 Jun 1;5:10758. doi: 10.1038/srep10758.

44.

Usefulness of immunohistochemical studies in diagnosing metachronous gallbladder and small intestinal metastases from lung cancer with gastrointestinal hemorrhage: a case report.

Tanaka M, Kitago M, Akiyama N, Iwamaru A, Yamamoto T, Suzuki F, Hibi T, Abe Y, Yagi H, Shinoda M, Itano O, Ogata K, Kitagawa Y.

World J Surg Oncol. 2015 Feb 18;13:63. doi: 10.1186/s12957-015-0435-7.

45.

Mechanism of Oncogenic Signal Activation by the Novel Fusion Kinase FGFR3-BAIAP2L1.

Nakanishi Y, Akiyama N, Tsukaguchi T, Fujii T, Satoh Y, Ishii N, Aoki M.

Mol Cancer Ther. 2015 Mar;14(3):704-12. doi: 10.1158/1535-7163.MCT-14-0927-T. Epub 2015 Jan 14.

46.

Limitation of immune tolerance-inducing thymic epithelial cell development by Spi-B-mediated negative feedback regulation.

Akiyama N, Shinzawa M, Miyauchi M, Yanai H, Tateishi R, Shimo Y, Ohshima D, Matsuo K, Sasaki I, Hoshino K, Wu G, Yagi S, Inoue J, Kaisho T, Akiyama T.

J Exp Med. 2014 Nov 17;211(12):2425-38. doi: 10.1084/jem.20141207. Epub 2014 Nov 10.

47.

Repeated administration of IL-31 upregulates IL-31 receptor A (IL-31RA) in dorsal root ganglia and causes severe itch-associated scratching behaviour in mice.

Arai I, Tsuji M, Miyagawa K, Takeda H, Akiyama N, Saito S.

Exp Dermatol. 2015 Jan;24(1):75-8. doi: 10.1111/exd.12587. Epub 2014 Dec 20.

PMID:
25381841
48.

Pure psychiatric presentation of the Lewy body disease is depression--an analysis of 60 cases verified with myocardial meta-iodobenzylguanidine study.

Kobayashi K, Nakano H, Akiyama N, Maeda T, Yamamori S.

Int J Geriatr Psychiatry. 2015 Jun;30(6):663-8. doi: 10.1002/gps.4214. Epub 2014 Oct 22.

PMID:
25335897
49.

Aberrant levels of histone H3 acetylation induce spermatid anomaly in mouse testis.

Dai L, Endo D, Akiyama N, Yamamoto-Fukuda T, Koji T.

Histochem Cell Biol. 2015 Feb;143(2):209-24. doi: 10.1007/s00418-014-1283-1. Epub 2014 Oct 19.

PMID:
25326673
50.

KGFR as a possible therapeutic target in middle ear cholesteatoma.

Yamamoto-Fukuda T, Akiyama N, Shibata Y, Takahashi H, Ikeda T, Kohno M, Koji T.

Acta Otolaryngol. 2014 Nov;134(11):1121-7. doi: 10.3109/00016489.2014.907501.

PMID:
25315911

Supplemental Content

Loading ...
Support Center