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Items: 38

1.

Cathepsin B Is Dispensable for Cellular Processing of Cathepsin B-Cleavable Antibody-Drug Conjugates.

Caculitan NG, Dela Cruz Chuh J, Ma Y, Zhang D, Kozak KR, Liu Y, Pillow TH, Sadowsky J, Cheung TK, Phung Q, Haley B, Lee BC, Akita RW, Sliwkowski MX, Polson AG.

Cancer Res. 2017 Dec 15;77(24):7027-7037. doi: 10.1158/0008-5472.CAN-17-2391. Epub 2017 Oct 18.

PMID:
29046337
2.

Case Report of a Large Pigmented Epithelioid Melanocytoma With Suspected Lymph Node Metastases.

Akita R, Sowa Y, Morita D, Numajiri T.

Eplasty. 2016 Dec 16;16:e33. eCollection 2016.

3.

High cell-surface density of HER2 deforms cell membranes.

Chung I, Reichelt M, Shao L, Akita RW, Koeppen H, Rangell L, Schaefer G, Mellman I, Sliwkowski MX.

Nat Commun. 2016 Sep 7;7:12742. doi: 10.1038/ncomms12742.

4.

Ring Selective Generation of Isobenzofuran for Divergent Access to Polycyclic Aromatic Compounds.

Akita R, Kawanishi K, Hamura T.

Org Lett. 2015 Jun 19;17(12):3094-7. doi: 10.1021/acs.orglett.5b01364. Epub 2015 Jun 9.

PMID:
26057708
5.

[Proposal of endogenous anticholinergic hypothesis in Alzheimer disease].

Hori K, Konishi K, Akita R, Tani M, Tomioka H, Kitajima Y, Yokoyama S, Azuma K, Ikuse D, Akashi N, Yuda H, Hachisu M.

Nihon Shinkei Seishin Yakurigaku Zasshi. 2013 Jun;33(3):117-26. Review. Japanese.

PMID:
25069245
6.

Serum anticholinergic activity: a possible peripheral marker of the anticholinergic burden in the central nervous system in Alzheimer's disease.

Hori K, Konishi K, Tani M, Tomioka H, Akita R, Kitajima Y, Aoki M, Yokoyama S, Azuma K, Ikuse D, Akashi N, Hosoi M, Jinbo K, Hachisu M.

Dis Markers. 2014;2014:459013. doi: 10.1155/2014/459013. Epub 2014 Feb 9. Review.

7.

Congenital syndactyly: case by case analysis of 47 patients.

Mandarano-Filho LG, Bezuti MT, Akita R, Mazzer N, Barbieri CH.

Acta Ortop Bras. 2013;21(6):333-5. doi: 10.1590/S1413-78522013000600007.

8.

Development and validation of a lateral flow assay for the detection of crustacean protein in processed foods.

Koizumi D, Shirota K, Akita R, Oda H, Akiyama H.

Food Chem. 2014 May 1;150:348-52. doi: 10.1016/j.foodchem.2013.10.130. Epub 2013 Nov 4.

PMID:
24360461
9.

Fluvoxamine and celecoxib may have caused adverse events in an elderly patient.

Hori K, Konishi K, Akita R, Tanaka H, Hachisu M.

Psychiatry Clin Neurosci. 2013 Jul;67(5):363. doi: 10.1111/pcn.12062. No abstract available.

10.

Donepezil abolishes anticholinergic activity in a patient with amnesia.

Konishi K, Hori K, Tomioka H, Minegishi G, Tani M, Tanaka H, Akita R, Yokoyama S, Oshio T, Hachisu M.

Pharmacology. 2013;91(1-2):86-91. doi: 10.1159/000345344. Epub 2012 Dec 14.

11.

Is anticholinergic activity related with Parkinson's disease?

Konishi K, Hori K, Tomioka H, Tani M, Tanaka H, Akita R, Yokoyama S, Oshio T, Hachisu M.

Psychogeriatrics. 2012 Sep;12(3):214. doi: 10.1111/j.1479-8301.2011.00392.x. No abstract available.

12.

[JSNP Excellent Presentation Award for AsCNP 2011: an analysis of pharmacotherapy combined cognitive-behavioral group therapy for panic disorder with agoraphobia].

Takashio O, Kokubo Y, Akita R, Tanaka H, Sakagami K, Shimizu H, Okajima Y, Nakamura D, Akashi N, Kato N.

Nihon Shinkei Seishin Yakurigaku Zasshi. 2012 Apr;32(2):105-7. Japanese. No abstract available.

PMID:
22708267
13.
14.

Spatial control of EGF receptor activation by reversible dimerization on living cells.

Chung I, Akita R, Vandlen R, Toomre D, Schlessinger J, Mellman I.

Nature. 2010 Apr 1;464(7289):783-7. doi: 10.1038/nature08827. Epub 2010 Mar 7.

PMID:
20208517
15.

Ligand-independent HER2/HER3/PI3K complex is disrupted by trastuzumab and is effectively inhibited by the PI3K inhibitor GDC-0941.

Junttila TT, Akita RW, Parsons K, Fields C, Lewis Phillips GD, Friedman LS, Sampath D, Sliwkowski MX.

Cancer Cell. 2009 May 5;15(5):429-40. doi: 10.1016/j.ccr.2009.03.020. Erratum in: Cancer Cell. 2011 Dec 13;20(6):818.

16.

70 S ribosomes bind to Shine-Dalgarno sequences without required dissociations.

Takahashi S, Akita R, Matsuno H, Furusawa H, Shimizu Y, Ueda T, Okahata Y.

Chembiochem. 2008 Apr 14;9(6):870-3. doi: 10.1002/cbic.200700679. No abstract available.

PMID:
18338356
18.

Kinetic analysis of ribosome binding process onto mRNA using a quartz-crystal microbalance.

Takahashi S, Akita R, Furusawa H, Shimizu Y, Ueda T, Okahata Y.

Nucleic Acids Symp Ser (Oxf). 2006;(50):49-50.

PMID:
17150811
19.

Therapeutic effect of hyperbaric oxygen in hepatic artery thrombosis and functional cholestasis after orthotopic liver transplantation.

Castro e Silva O, Sankarankutty AK, Martinelli AL, Souza FF, Teixeira AC, Feres O, Mente ED, Oliveira GR, Akita R, Muglia V, Elias J Jr, Ramalho LN, Zucoloto S.

Transplant Proc. 2006 Jul-Aug;38(6):1913-7.

PMID:
16908321
20.

Preclinical studies with Erlotinib (Tarceva).

Akita RW, Sliwkowski MX.

Semin Oncol. 2003 Jun;30(3 Suppl 7):15-24. Review. Erratum in: Semin Oncol. 2003 Dec;30(6):826.

PMID:
12840797
21.

Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth.

Agus DB, Akita RW, Fox WD, Lewis GD, Higgins B, Pisacane PI, Lofgren JA, Tindell C, Evans DP, Maiese K, Scher HI, Sliwkowski MX.

Cancer Cell. 2002 Aug;2(2):127-37.

22.

Identification of a region within the ErbB2/HER2 intracellular domain that is necessary for ligand-independent association.

Penuel E, Akita RW, Sliwkowski MX.

J Biol Chem. 2002 Aug 9;277(32):28468-73. Epub 2002 May 8.

23.

Structural requirements for ErbB2 transactivation.

Penuel E, Schaefer G, Akita RW, Sliwkowski MX.

Semin Oncol. 2001 Dec;28(6 Suppl 18):36-42. Review.

PMID:
11774204
24.
25.

A potential role for activated HER-2 in prostate cancer.

Agus DB, Akita RW, Fox WD, Lofgren JA, Higgins B, Maiese K, Scher HI, Sliwkowski MX.

Semin Oncol. 2000 Dec;27(6 Suppl 11):76-83; discussion 92-100. Review.

PMID:
11236032
26.

Biologic effects of heregulin/neu differentiation factor on normal and malignant human breast and ovarian epithelial cells.

Aguilar Z, Akita RW, Finn RS, Ramos BL, Pegram MD, Kabbinavar FF, Pietras RJ, Pisacane P, Sliwkowski MX, Slamon DJ.

Oncogene. 1999 Oct 28;18(44):6050-62.

27.

Binding specificities and affinities of egf domains for ErbB receptors.

Jones JT, Akita RW, Sliwkowski MX.

FEBS Lett. 1999 Mar 26;447(2-3):227-31.

28.
29.

Selection of heregulin variants having higher affinity for the ErbB3 receptor by monovalent phage display.

Ballinger MD, Jones JT, Lofgren JA, Fairbrother WJ, Akita RW, Sliwkowski MX, Wells JA.

J Biol Chem. 1998 May 8;273(19):11675-84.

30.

Neuregulin-3 (NRG3): a novel neural tissue-enriched protein that binds and activates ErbB4.

Zhang D, Sliwkowski MX, Mark M, Frantz G, Akita R, Sun Y, Hillan K, Crowley C, Brush J, Godowski PJ.

Proc Natl Acad Sci U S A. 1997 Sep 2;94(18):9562-7.

31.

Coexpression of erbB2 and erbB3 proteins reconstitutes a high affinity receptor for heregulin.

Sliwkowski MX, Schaefer G, Akita RW, Lofgren JA, Fitzpatrick VD, Nuijens A, Fendly BM, Cerione RA, Vandlen RL, Carraway KL 3rd.

J Biol Chem. 1994 May 20;269(20):14661-5.

32.

The erbB3 gene product is a receptor for heregulin.

Carraway KL 3rd, Sliwkowski MX, Akita R, Platko JV, Guy PM, Nuijens A, Diamonti AJ, Vandlen RL, Cantley LC, Cerione RA.

J Biol Chem. 1994 May 13;269(19):14303-6.

33.

Her-2/neu expression in node-negative breast cancer: direct tissue quantitation by computerized image analysis and association of overexpression with increased risk of recurrent disease.

Press MF, Pike MC, Chazin VR, Hung G, Udove JA, Markowicz M, Danyluk J, Godolphin W, Sliwkowski M, Akita R, et al.

Cancer Res. 1993 Oct 15;53(20):4960-70.

34.

Identification of heregulin, a specific activator of p185erbB2.

Holmes WE, Sliwkowski MX, Akita RW, Henzel WJ, Lee J, Park JW, Yansura D, Abadi N, Raab H, Lewis GD, et al.

Science. 1992 May 22;256(5060):1205-10.

PMID:
1350381
35.

An antigen immunologically related to the external domain of gp185 is shed from nude mouse tumors overexpressing the c-erbB-2 (HER-2/neu) oncogene.

Langton BC, Crenshaw MC, Chao LA, Stuart SG, Akita RW, Jackson JE.

Cancer Res. 1991 May 15;51(10):2593-8.

36.

Serological evaluation of Escherichia coli-expressed human T-cell leukemia virus type I env, gag p24, and tax proteins.

Coates SR, Harris AJ, Parkes DL, Smith CM, Liu HL, Akita RW, Ferrer MM, Sampson EK, Brandis JW, Sliwkowski MX.

J Clin Microbiol. 1990 Jun;28(6):1139-42.

38.

[Medical care accompanied by nursing service in a private clinic--a trial and prospect of private practice. Discussion].

Shioda Y, Shioda C, Akita R, Ishida M, Kitamura E.

Kangogaku Zasshi. 1980 Jun;44(6):590-603. Japanese. No abstract available.

PMID:
6770142

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