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Items: 1 to 50 of 396

1.

Two cases of sporadic adult-onset neuronal intranuclear inclusion disease preceded by urinary disturbance for many years.

Nakamura M, Ueki S, Kubo M, Yagi H, Sasaki R, Okada Y, Akiguchi I, Kusaka H, Kondo T.

J Neurol Sci. 2018 Sep 15;392:89-93. doi: 10.1016/j.jns.2018.07.012. Epub 2018 Jul 17.

PMID:
30031993
2.

The relationship between progressive motor deficits and lesion location in patients with single infarction in the lenticulostriate artery territory.

Yamamoto Y, Nagakane Y, Tomii Y, Toda S, Akiguchi I.

J Neurol. 2017 Jul;264(7):1381-1387. doi: 10.1007/s00415-017-8533-9. Epub 2017 Jun 8.

PMID:
28597318
3.

SAMP8 mice as a neuropathological model of accelerated brain aging and dementia: Toshio Takeda's legacy and future directions.

Akiguchi I, Pallàs M, Budka H, Akiyama H, Ueno M, Han J, Yagi H, Nishikawa T, Chiba Y, Sugiyama H, Takahashi R, Unno K, Higuchi K, Hosokawa M.

Neuropathology. 2017 Aug;37(4):293-305. doi: 10.1111/neup.12373. Epub 2017 Mar 6. Review.

PMID:
28261874
4.

Sex-related difference in human white matter volumes studied: Inspection of the corpus callosum and other white matter by VBM.

Shiino A, Chen YW, Tanigaki K, Yamada A, Vigers P, Watanabe T, Tooyama I, Akiguchi I.

Sci Rep. 2017 Jan 3;7:39818. doi: 10.1038/srep39818.

5.

High Morning and Bedtime Home Blood Pressures Strongly Predict for Post-Stroke Cognitive Impairment.

Yamamoto Y, Nagakane Y, Tomii Y, Akiguchi I.

J Stroke Cerebrovasc Dis. 2016 Aug;25(8):1856-63. doi: 10.1016/j.jstrokecerebrovasdis.2016.04.001. Epub 2016 May 2.

PMID:
27156901
6.

[Prediction of conversion from amnestic mild cognitive impairment to Alzheimer's disease using proton magnetic resonance spectroscopy].

Watanabe T, Shiino A, Akiguchi I.

Rinsho Shinkeigaku. 2015;55(10):709-15. doi: 10.5692/clinicalneurol.cn-000751. Epub 2015 Sep 11. Japanese.

PMID:
26369373
7.

MRI features of Binswanger's disease predict prognosis and associated pathology.

Akiguchi I, Budka H, Shirakashi Y, Woehrer A, Watanabe T, Shiino A, Yamamoto Y, Kawamoto Y, Krampla W, Jungwirth S, Fischer P.

Ann Clin Transl Neurol. 2014 Oct;1(10):813-21. doi: 10.1002/acn3.123. Epub 2014 Oct 6.

8.

Disproportionate subarachnoid space hydrocephalus-outcome and perivascular space.

Akiguchi I, Shirakashi Y, Budka H, Watanabe Y, Watanabe T, Shiino A, Ogita M, Kawamoto Y, Jungwirth S, Krampla W, Fischer P.

Ann Clin Transl Neurol. 2014 Aug;1(8):562-9. doi: 10.1002/acn3.87. Epub 2014 Jul 28.

9.

Aggressive antiplatelet treatment for acute branch atheromatous disease type infarcts: a 12-year prospective study.

Yamamoto Y, Nagakane Y, Makino M, Ohara T, Koizumi T, Makita N, Akiguchi I.

Int J Stroke. 2014 Apr;9(3):E8. doi: 10.1111/ijs.12200. No abstract available.

10.
11.

Hippocampal metabolites and memory performances in patients with amnestic mild cognitive impairment and Alzheimer's disease.

Watanabe T, Shiino A, Akiguchi I.

Neurobiol Learn Mem. 2012 Mar;97(3):289-93. doi: 10.1016/j.nlm.2012.01.006. Epub 2012 Feb 27.

PMID:
22390859
12.

The profile of hippocampal metabolites differs between Alzheimer's disease and subcortical ischemic vascular dementia, as measured by proton magnetic resonance spectroscopy.

Shiino A, Watanabe T, Shirakashi Y, Kotani E, Yoshimura M, Morikawa S, Inubushi T, Akiguchi I.

J Cereb Blood Flow Metab. 2012 May;32(5):805-15. doi: 10.1038/jcbfm.2012.9. Epub 2012 Feb 8.

13.

Chronic kidney disease, 24-h blood pressure and small vessel diseases are independently associated with cognitive impairment in lacunar infarct patients.

Yamamoto Y, Ohara T, Nagakane Y, Tanaka E, Morii F, Koizumi T, Akiguchi I.

Hypertens Res. 2011 Dec;34(12):1276-82. doi: 10.1038/hr.2011.118. Epub 2011 Aug 11.

PMID:
21832998
14.

Morphometric characterization of Binswanger's disease: comparison with Alzheimer's disease.

Shiino A, Akiguchi I, Watanabe T, Shirakashi Y, Nozaki K, Tooyama I, Inubushi T.

Eur J Radiol. 2012 Sep;81(9):2375-9. doi: 10.1016/j.ejrad.2011.05.031. Epub 2011 Jun 25.

PMID:
21708443
15.

Characteristics of intracranial branch atheromatous disease and its association with progressive motor deficits.

Yamamoto Y, Ohara T, Hamanaka M, Hosomi A, Tamura A, Akiguchi I.

J Neurol Sci. 2011 May 15;304(1-2):78-82. doi: 10.1016/j.jns.2011.02.006. Epub 2011 Mar 13.

PMID:
21402390
16.

Parkinsonian Symptomatology May Correlate with CT Findings before and after Shunting in Idiopathic Normal Pressure Hydrocephalus.

Ishii M, Kawamata T, Akiguchi I, Yagi H, Watanabe Y, Watanabe T, Mashimo H.

Parkinsons Dis. 2010 Mar 10;2010. pii: 201089. doi: 10.4061/2010/201089.

17.

Absolute quantification in proton magnetic resonance spectroscopy is useful to differentiate amnesic mild cognitive impairment from Alzheimer's disease and healthy aging.

Watanabe T, Shiino A, Akiguchi I.

Dement Geriatr Cogn Disord. 2010;30(1):71-7. doi: 10.1159/000318750. Epub 2010 Aug 5.

18.

HtrA2/Omi-immunoreactive intraneuronal inclusions in the anterior horn of patients with sporadic and Cu/Zn superoxide dismutase (SOD1) mutant amyotrophic lateral sclerosis.

Kawamoto Y, Ito H, Kobayashi Y, Suzuki Y, Akiguchi I, Fujimura H, Sakoda S, Kusaka H, Hirano A, Takahashi R.

Neuropathol Appl Neurobiol. 2010 Jun;36(4):331-44. doi: 10.1111/j.1365-2990.2010.01075.x. Epub 2010 Feb 25.

PMID:
20202124
19.

Vascular mechanisms of cognitive impairment: roles of hypertension and subsequent small vessel disease under sympathetic influences.

Akiguchi I, Yamamoto Y.

Hypertens Res. 2010 Jan;33(1):29-31. doi: 10.1038/hr.2009.189. Epub 2009 Nov 13. No abstract available.

PMID:
19911000
20.

Predictive factors for progressive motor deficits in penetrating artery infarctions in two different arterial territories.

Yamamoto Y, Ohara T, Hamanaka M, Hosomi A, Tamura A, Akiguchi I, Ozasa K.

J Neurol Sci. 2010 Jan 15;288(1-2):170-4. doi: 10.1016/j.jns.2009.08.065.

PMID:
19836756
21.

Anti-DARPP32 antibody-immunopositive inclusions in the brain of patients with multiple system atrophy.

Honjo Y, Shirakashi Y, Kawamoto Y, Akiguchi I.

Clin Neuropathol. 2008 Sep-Oct;27(5):309-16.

PMID:
18808062
22.

Accumulation of HtrA2/Omi in neuronal and glial inclusions in brains with alpha-synucleinopathies.

Kawamoto Y, Kobayashi Y, Suzuki Y, Inoue H, Tomimoto H, Akiguchi I, Budka H, Martins LM, Downward J, Takahashi R.

J Neuropathol Exp Neurol. 2008 Oct;67(10):984-93. doi: 10.1097/NEN.0b013e31818809f4.

PMID:
18800009
23.

Different atrophic patterns in early- and late-onset Alzheimer's disease and evaluation of clinical utility of a method of regional z-score analysis using voxel-based morphometry.

Shiino A, Watanabe T, Kitagawa T, Kotani E, Takahashi J, Morikawa S, Akiguchi I.

Dement Geriatr Cogn Disord. 2008;26(2):175-86. doi: 10.1159/000151241. Epub 2008 Aug 12.

PMID:
18698140
24.

Age-related changes in barrier function in mouse brain II. Accumulation of serum albumin in the olfactory bulb of SAM mice increased with aging.

Ueno M, Akiguchi I, Hosokawa M, Shinnou M, Sakamoto H, Takemura M, Higuchi K.

Arch Gerontol Geriatr. 1997 Nov-Dec;25(3):321-31.

PMID:
18653120
25.

A computer support system for neurological anatomical diagnosis.

Kamo H, Kiriyama Y, Mizoe A, Murase E, Okajima S, Akiguchi I, Hirasawa Y, McGeer PL.

Clin Neurol Neurosurg. 2008 Dec;110(10):973-8. doi: 10.1016/j.clineuro.2008.05.022. Epub 2008 Jul 14.

PMID:
18621473
26.

Absolute quantification in proton magnetic resonance spectroscopy is superior to relative ratio to discriminate Alzheimer's disease from Binswanger's disease.

Watanabe T, Shiino A, Akiguchi I.

Dement Geriatr Cogn Disord. 2008;26(1):89-100. doi: 10.1159/000144044. Epub 2008 Jul 11.

PMID:
18617735
27.

Shunt-responsive parkinsonism and reversible white matter lesions in patients with idiopathic NPH.

Akiguchi I, Ishii M, Watanabe Y, Watanabe T, Kawasaki T, Yagi H, Shiino A, Shirakashi Y, Kawamoto Y.

J Neurol. 2008 Sep;255(9):1392-9. doi: 10.1007/s00415-008-0928-1. Epub 2008 Jun 27.

PMID:
18575921
28.

Hypoxia-inducible factor 1alpha may be a marker for vasculitic neuropathy.

Oka N, Kawasaki T, Mizutani K, Sugiyama H, Akiguchi I.

Neuropathology. 2007 Dec;27(6):509-15.

PMID:
18021370
29.

[The prevention and therapy of vascular dementia: an update].

Akiguchi I, Watanabe Y, Yagi H.

Nihon Rinsho. 2006 Nov 28;64 Suppl 8:792-6. Review. Japanese. No abstract available.

PMID:
17471665
30.

[Brainstem infarction (pons)].

Akiguchi I, Yamamoto Y, Harada K.

Nihon Rinsho. 2006 Nov 28;64 Suppl 8:214-9. Review. Japanese. No abstract available.

PMID:
17469555
31.

Accumulation of triosephosphate isomerase, with sequence homology to Beta amyloid peptides, in vessel walls of the newborn piglet hippocampus.

Kusaka T, Ueno M, Miki T, Kanenishi K, Nagai Y, Huang CL, Okamoto Y, Ogawa T, Onodera M, Itoh S, Akiguchi I, Sakamoto H.

Microsc Res Tech. 2007 Jul;70(7):648-55.

PMID:
17393492
32.

Accumulation of Hsc70 and Hsp70 in glial cytoplasmic inclusions in patients with multiple system atrophy.

Kawamoto Y, Akiguchi I, Shirakashi Y, Honjo Y, Tomimoto H, Takahashi R, Budka H.

Brain Res. 2007 Mar 9;1136(1):219-27. Epub 2006 Dec 22.

PMID:
17240362
33.

Four subgroups of Alzheimer's disease based on patterns of atrophy using VBM and a unique pattern for early onset disease.

Shiino A, Watanabe T, Maeda K, Kotani E, Akiguchi I, Matsuda M.

Neuroimage. 2006 Oct 15;33(1):17-26. Epub 2006 Aug 10.

PMID:
16904912
34.

[Pathophysiology and therapeutic approaches on Binswanger's disease].

Akiguchi I.

No To Shinkei. 2006 Apr;58(4):289-97. Review. Japanese. No abstract available.

PMID:
16681257
35.

Nationwide survey of juvenile muscular atrophy of distal upper extremity (Hirayama disease) in Japan.

Tashiro K, Kikuchi S, Itoyama Y, Tokumaru Y, Sobue G, Mukai E, Akiguchi I, Nakashima K, Kira J, Hirayama K.

Amyotroph Lateral Scler. 2006 Mar;7(1):38-45.

PMID:
16546758
36.

Upregulated expression of 14-3-3 proteins in astrocytes from human cerebrovascular ischemic lesions.

Kawamoto Y, Akiguchi I, Tomimoto H, Shirakashi Y, Honjo Y, Budka H.

Stroke. 2006 Mar;37(3):830-5. Epub 2006 Jan 19.

PMID:
16424378
37.

Cultured murine dermal fibroblast-like cells from senescence-accelerated mice as in vitro models for higher oxidative stress due to mitochondrial alterations.

Chiba Y, Yamashita Y, Ueno M, Fujisawa H, Hirayoshi K, Hohmura K, Tomimoto H, Akiguchi I, Satoh M, Shimada A, Hosokawa M.

J Gerontol A Biol Sci Med Sci. 2005 Sep;60(9):1087-98.

PMID:
16183946
38.

14-3-3 proteins in Lewy body-like hyaline inclusions in a patient with familial amyotrophic lateral sclerosis with a two-base pair deletion in the Cu/Zn superoxide dismutase (SOD1) gene.

Kawamoto Y, Akiguchi I, Fujimura H, Shirakashi Y, Honjo Y, Sakoda S.

Acta Neuropathol. 2005 Aug;110(2):203-4. Epub 2005 Jun 23. No abstract available.

PMID:
15973542
39.

The relationship between 24-hour blood pressure readings, subcortical ischemic lesions and vascular dementia.

Yamamoto Y, Akiguchi I, Oiwa K, Hayashi M, Ohara T, Ozasa K.

Cerebrovasc Dis. 2005;19(5):302-8. Epub 2005 Mar 17.

PMID:
15775671
40.

CD16+CD57- natural killer cells in multifocal motor neuropathy.

Mizutani K, Oka N, Kaji R, Matsui M, Asanuma K, Kubori T, Kojima Y, Kanda M, Kawanishi T, Tomimoto H, Akiguchi I, Shibasaki H.

Eur Neurol. 2005;53(2):64-7. Epub 2005 Mar 7.

PMID:
15753615
41.

Astroglial expression of ceramide in Alzheimer's disease brains: a role during neuronal apoptosis.

Satoi H, Tomimoto H, Ohtani R, Kitano T, Kondo T, Watanabe M, Oka N, Akiguchi I, Furuya S, Hirabayashi Y, Okazaki T.

Neuroscience. 2005;130(3):657-66.

PMID:
15590150
42.

14-3-3 proteins in Lewy body-like hyaline inclusions in patients with sporadic amyotrophic lateral sclerosis.

Kawamoto Y, Akiguchi I, Nakamura S, Budka H.

Acta Neuropathol. 2004 Dec;108(6):531-7. Epub 2004 Sep 18.

PMID:
15378322
43.

Upregulation of ceramide and its regulating mechanism in a rat model of chronic cerebral ischemia.

Ohtani R, Tomimoto H, Kondo T, Wakita H, Akiguchi I, Shibasaki H, Okazaki T.

Brain Res. 2004 Oct 8;1023(1):31-40.

PMID:
15364016
44.

A compensatory mechanism in unilateral akinetic-rigid syndrome: an fMRI study.

Kinomoto K, Takayama Y, Abe M, Nakamura K, Akiguchi I.

Clin Neurol Neurosurg. 2004 Sep;106(4):330-4.

PMID:
15297009
45.

Enhanced expression of 14-3-3 proteins in reactive astrocytes in Creutzfeldt-Jakob disease brains.

Kawamoto Y, Akiguchi I, Jarius C, Budka H.

Acta Neuropathol. 2004 Oct;108(4):302-8. Epub 2004 Jul 3.

PMID:
15235801
46.

Topographical and cytopathological lesion analysis of the white matter in Binswanger's disease brains.

Akiguchi I, Tomimoto H, Wakita H, Kawamoto Y, Matsuo A, Ohnishi K, Watanabe T, Budka H.

Acta Neuropathol. 2004 Jun;107(6):563-70. Epub 2004 Apr 15.

PMID:
15088098
47.

Blood-brain barrier is impaired in the hippocampus of young adult spontaneously hypertensive rats.

Ueno M, Sakamoto H, Tomimoto H, Akiguchi I, Onodera M, Huang CL, Kanenishi K.

Acta Neuropathol. 2004 Jun;107(6):532-8. Epub 2004 Mar 20.

PMID:
15042385
48.

Hypertensive brainstem encephalopathy.

Yasuda Y, Akiguchi I, Imai T, Sonobe M, Kage M.

Intern Med. 2003 Nov;42(11):1131-4.

49.

Increased 14-3-3 immunoreactivity in glial elements in patients with multiple sclerosis.

Kawamoto Y, Akiguchi I, Kovács GG, Flicker H, Budka H.

Acta Neuropathol. 2004 Feb;107(2):137-43. Epub 2003 Nov 6.

PMID:
14605832
50.

Ibudilast, a phosphodiesterase inhibitor, protects against white matter damage under chronic cerebral hypoperfusion in the rat.

Wakita H, Tomimoto H, Akiguchi I, Lin JX, Ihara M, Ohtani R, Shibata M.

Brain Res. 2003 Nov 28;992(1):53-9.

PMID:
14604772

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