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Inhibition of Postinfarction Ventricular Remodeling by High Molecular Weight Polyethylene Glycol.

Razzaque MA, Xu X, Han M, Badami A, Akhter SA.

J Surg Res. 2018 Dec;232:171-178. doi: 10.1016/j.jss.2018.05.035. Epub 2018 Jul 5.


Outcomes of surgical aortic valve replacement for mixed aortic valve disease.

Philip JL, Zens T, Lozonschi L, De Oliveira NC, Osaki S, Kohmoto T, Akhter SA, Tang PC.

J Thorac Dis. 2018 Jul;10(7):4042-4051. doi: 10.21037/jtd.2018.06.128.


Increased risk of atrial fibrillation among patients undergoing coronary artery bypass graft surgery while receiving nitrates and antiplatelet agents.

Efird JT, Jindal C, Kiser AC, Akhter SA, Crane PB, Kypson AP, Sverdlov AL, Davies SW, Kindell LC, Anderson EJ.

J Int Med Res. 2018 Aug;46(8):3183-3194. doi: 10.1177/0300060518773934. Epub 2018 May 29.


Coronary Events in Patients Presenting for Repair of Acute Type A Aortic Dissection.

Tang PC, Akhter SA, Osaki S, Lozonschi L, Kohmoto T, De Oliveira NC.

Aorta (Stamford). 2017 Jun 1;5(3):71-79. doi: 10.12945/j.aorta.2017.16.058. eCollection 2017 Jun.


Natural history of the proximal aorta in patients with descending thoracic aortic disease.

Tang PC, DiMusto PD, De Oliveira NC, Rademacher BL, Philip JL, Akhter SA, Acher CW.

J Vasc Surg. 2018 Jun;67(6):1659-1663. doi: 10.1016/j.jvs.2017.10.062. Epub 2017 Dec 21.


Cluster analysis of acute ascending aortic dissection provides novel insight into mechanisms of distal progression.

Philip JL, De Oliveira NC, Akhter SA, Rademacher BL, Goodavish CB, DiMusto PD, Tang PC.

J Thorac Dis. 2017 Sep;9(9):2966-2973. doi: 10.21037/jtd.2017.08.06.


Cardiac Surgery Outcomes in Abdominal Solid Organ Transplant Recipients.

Kohmoto T, Osaki S, Kaufman DB, Leverson G, DeOliveira N, Akhter SA, Ulschmid S, Lozonschi L, Lushaj EB.

Ann Thorac Surg. 2018 Mar;105(3):757-762. doi: 10.1016/j.athoracsur.2017.09.002. Epub 2017 Nov 23.


Coronary bypass in left ventricular dysfunction and differential cardiac recovery.

Lozonschi L, Kohmoto T, Osaki S, De Oliveira NC, Dhingra R, Akhter SA, Tang PC.

Asian Cardiovasc Thorac Ann. 2017 Nov;25(9):586-593. doi: 10.1177/0218492317744472. Epub 2017 Nov 20.


Acute retrograde type A aortic dissection: morphologic analysis and clinical implications.

DiMusto PD, Rademacher BL, Philip JL, Akhter SA, Goodavish CB, De Oliveira NC, Tang PC.

J Surg Res. 2017 Jun 1;213:39-45. doi: 10.1016/j.jss.2017.02.034. Epub 2017 Feb 27.


Efficacy of Aortic Valve Resuspension in Establishing Valve Competence in Acute Type A Dissections.

Tang PC, Badami A, Akhter SA, Osaki S, Lozonschi L, Kohmoto T, De Oliveira N.

Ann Thorac Surg. 2017 May;103(5):1460-1466. doi: 10.1016/j.athoracsur.2016.08.099. Epub 2016 Nov 15.


Outpatient air leak management after lobectomy: a CMS cost analysis.

Schmocker RK, Vanness DJ, Macke RA, Akhter SA, Maloney JD, Blasberg JD.

J Surg Res. 2016 Jun 15;203(2):390-7. doi: 10.1016/j.jss.2016.03.043. Epub 2016 Mar 26.


Continuous-flow left ventricular assist devices and bleeding events: Is there a biological role for decreasing pump speed?

Akhter SA.

J Thorac Cardiovasc Surg. 2016 Jun;151(6):1755-6. doi: 10.1016/j.jtcvs.2016.02.027. Epub 2016 Feb 16. No abstract available.


Regulation of cellular oxidative stress and apoptosis by G protein-coupled receptor kinase-2; The role of NADPH oxidase 4.

Theccanat T, Philip JL, Razzaque AM, Ludmer N, Li J, Xu X, Akhter SA.

Cell Signal. 2016 Mar;28(3):190-203. doi: 10.1016/j.cellsig.2015.11.013. Epub 2015 Nov 27.


Regulation of mitochondrial oxidative stress by β-arrestins in cultured human cardiac fibroblasts.

Philip JL, Razzaque MA, Han M, Li J, Theccanat T, Xu X, Akhter SA.

Dis Model Mech. 2015 Dec;8(12):1579-89. doi: 10.1242/dmm.019968. Epub 2015 Oct 8.


Invited Commentary.

Akhter SA.

Ann Thorac Surg. 2015 Oct;100(4):1297. doi: 10.1016/j.athoracsur.2015.05.025. No abstract available.


A novel approach to prevent post-operative ileus after continuous-flow left ventricular assist device implantation: A retrospective cohort study.

Badami A, Fehrenbach Prell EA, Murray MA, Johnson MR, Akhter SA, Lozonschi L, Osaki S, Lushaj E, Kohmoto T.

Int J Surg. 2015 Aug;20:135-9. doi: 10.1016/j.ijsu.2015.06.054. Epub 2015 Jun 26.


Hospital Readmissions After Continuous-Flow Left Ventricular Assist Device Implantation: Incidence, Causes, and Cost Analysis.

Akhter SA, Badami A, Murray M, Kohmoto T, Lozonschi L, Osaki S, Lushaj EB.

Ann Thorac Surg. 2015 Sep;100(3):884-9. doi: 10.1016/j.athoracsur.2015.03.010. Epub 2015 Jun 19.


Reduction in driveline infection rates: Results from the HeartMate II Multicenter Driveline Silicone Skin Interface (SSI) Registry.

Dean D, Kallel F, Ewald GA, Tatooles A, Sheridan BC, Brewer RJ, Caldeira C, Farrar DJ, Akhter SA; SSI Registry Investigators.

J Heart Lung Transplant. 2015 Jun;34(6):781-9. doi: 10.1016/j.healun.2014.11.021. Epub 2014 Dec 5.


High-molecular-weight polyethylene glycol inhibits myocardial ischemia-reperfusion injury in vivo.

Xu X, Philip JL, Razzaque MA, Lloyd JW, Muller CM, Akhter SA.

J Thorac Cardiovasc Surg. 2015 Feb;149(2):588-93. doi: 10.1016/j.jtcvs.2014.10.074. Epub 2014 Oct 18.


β-Arrestins regulate human cardiac fibroblast transformation and collagen synthesis in adverse ventricular remodeling.

Li J, Philip JL, Xu X, Theccanat T, Abdur Razzaque M, Akhter SA.

J Mol Cell Cardiol. 2014 Nov;76:73-83. doi: 10.1016/j.yjmcc.2014.08.006. Epub 2014 Aug 15.


Functional evaluation of human donation after cardiac death donor hearts using a continuous isolated myocardial perfusion technique: Potential for expansion of the cardiac donor population.

Osaki S, Locher MR, Lushaj EB, Akhter SA, Kohmoto T.

J Thorac Cardiovasc Surg. 2014 Sep;148(3):1123-30; discussion 1130. doi: 10.1016/j.jtcvs.2014.06.050. Epub 2014 Jul 5. Erratum in: J Thorac Cardiovasc Surg. 2015 Jan;149(1):398.


Modified HeartMate II driveline externalization technique significantly decreases incidence of infection and improves long-term survival.

Singh A, Russo MJ, Valeroso TB, Anderson AS, Rich JD, Jeevanandam V, Akhter SA.

ASAIO J. 2014 Nov-Dec;60(6):613-6. doi: 10.1097/MAT.0000000000000121.


Durability of De Vega tricuspid valve annuloplasty for severe tricuspid regurgitation during left ventricular assist device implantation.

Akhter SA, Salabat MR, Philip JL, Valeroso TB, Russo MJ, Rich JD, Jeevanandam V.

Ann Thorac Surg. 2014 Jul;98(1):81-3. doi: 10.1016/j.athoracsur.2014.03.022. Epub 2014 May 10.


Acute kidney injury and mortality following ventricular assist device implantation.

Naik A, Akhter SA, Fedson S, Jeevanandam V, Rich JD, Koyner JL.

Am J Nephrol. 2014;39(3):195-203. doi: 10.1159/000358495. Epub 2014 Feb 15.


Invited commentary.

Akhter SA.

Ann Thorac Surg. 2013 Apr;95(4):1281. doi: 10.1016/j.athoracsur.2013.01.017. No abstract available.


Invited commentary.

Akhter SA.

Ann Thorac Surg. 2013 Jan;95(1):61-2. doi: 10.1016/j.athoracsur.2012.09.001. Epub 2012 Dec 25. No abstract available.


GRK2-mediated inhibition of adrenergic and dopaminergic signaling in right ventricular hypertrophy: therapeutic implications in pulmonary hypertension.

Piao L, Fang YH, Parikh KS, Ryan JJ, D'Souza KM, Theccanat T, Toth PT, Pogoriler J, Paul J, Blaxall BC, Akhter SA, Archer SL.

Circulation. 2012 Dec 11;126(24):2859-69. doi: 10.1161/CIRCULATIONAHA.112.109868. Epub 2012 Nov 2.


The heart and pericardium.

Akhter SA.

Thorac Surg Clin. 2011 May;21(2):205-17, viii. doi: 10.1016/j.thorsurg.2011.01.007.


G protein-coupled receptor kinase-2 is a novel regulator of collagen synthesis in adult human cardiac fibroblasts.

D'Souza KM, Malhotra R, Philip JL, Staron ML, Theccanat T, Jeevanandam V, Akhter SA.

J Biol Chem. 2011 Apr 29;286(17):15507-16. doi: 10.1074/jbc.M111.218263. Epub 2011 Feb 25. Retraction in: J Biol Chem. 2015 Oct 23;290(43):25849.


High-molecular-weight polyethylene glycol protects cardiac myocytes from hypoxia- and reoxygenation-induced cell death and preserves ventricular function.

Malhotra R, Valuckaite V, Staron ML, Theccanat T, D'Souza KM, Alverdy JC, Akhter SA.

Am J Physiol Heart Circ Physiol. 2011 May;300(5):H1733-42. doi: 10.1152/ajpheart.01054.2010. Epub 2011 Feb 18.


Urinary biomarkers in the clinical prognosis and early detection of acute kidney injury.

Koyner JL, Vaidya VS, Bennett MR, Ma Q, Worcester E, Akhter SA, Raman J, Jeevanandam V, O'Connor MF, Devarajan P, Bonventre JV, Murray PT.

Clin J Am Soc Nephrol. 2010 Dec;5(12):2154-65. doi: 10.2215/CJN.00740110. Epub 2010 Aug 26.


Cardiac tamponade mimicking tuberculous pericarditis as the initial presentation of chronic lymphocytic leukemia in a 58-year-old woman: a case report.

Lin E, Boire A, Hemmige V, Husain AN, Sorrentino M, Nathan S, Akhter SA, Dickstein J, Archer SL.

J Med Case Rep. 2010 Aug 4;4:246. doi: 10.1186/1752-1947-4-246.


Reversal of impaired myocardial beta-adrenergic receptor signaling by continuous-flow left ventricular assist device support.

Akhter SA, D'Souza KM, Malhotra R, Staron ML, Valeroso TB, Fedson SE, Anderson AS, Raman J, Jeevanandam V.

J Heart Lung Transplant. 2010 Jun;29(6):603-9. doi: 10.1016/j.healun.2010.01.010. Epub 2010 Mar 4.


G alpha(q)-mediated activation of GRK2 by mechanical stretch in cardiac myocytes: the role of protein kinase C.

Malhotra R, D'Souza KM, Staron ML, Birukov KG, Bodi I, Akhter SA.

J Biol Chem. 2010 Apr 30;285(18):13748-60. doi: 10.1074/jbc.M110.109272. Epub 2010 Mar 1. Retraction in: Malhotra R, D'Souza KM, Staron ML, Birukov KG, Bodi I, Akhter SA. J Biol Chem. 2016 Jul 1;291(27):14390.


Technique for left ventricular apical cannulation for short-term mechanical circulatory support.

Akhter SA, Raman J, Jeevanandam V.

Ann Thorac Surg. 2010 Mar;89(3):994-5. doi: 10.1016/j.athoracsur.2009.04.143.


Molecular and functional characterization of a novel cardiac-specific human tropomyosin isoform.

Rajan S, Jagatheesan G, Karam CN, Alves ML, Bodi I, Schwartz A, Bulcao CF, D'Souza KM, Akhter SA, Boivin GP, Dube DK, Petrashevskaya N, Herr AB, Hullin R, Liggett SB, Wolska BM, Solaro RJ, Wieczorek DF.

Circulation. 2010 Jan 26;121(3):410-8. doi: 10.1161/CIRCULATIONAHA.109.889725. Epub 2010 Jan 11.


Activation of JAK-STAT and nitric oxide signaling as a mechanism for donor heart dysfunction.

Bulcao CF, D'Souza KM, Malhotra R, Staron M, Duffy JY, Pandalai PK, Jeevanandam V, Akhter SA.

J Heart Lung Transplant. 2010 Mar;29(3):346-51. doi: 10.1016/j.healun.2009.09.007.


Uncoupling of myocardial beta-adrenergic receptor signaling during coronary artery bypass grafting: the role of GRK2.

Bulcao CF, Pandalai PK, D'Souza KM, Merrill WH, Akhter SA.

Ann Thorac Surg. 2008 Oct;86(4):1189-94. doi: 10.1016/j.athoracsur.2008.05.042.


Unsymbolized thinking.

Hurlburt RT, Akhter SA.

Conscious Cogn. 2008 Dec;17(4):1364-74. doi: 10.1016/j.concog.2008.03.021. Epub 2008 May 5.


Acute beta-blockade prevents myocardial beta-adrenergic receptor desensitization and preserves early ventricular function after brain death.

Pandalai PK, McLean KM, Bulcao CF, Duffy JY, D'Souza KM, Merrill WH, Pearl JM, Akhter SA.

J Thorac Cardiovasc Surg. 2008 Apr;135(4):792-8. doi: 10.1016/j.jtcvs.2007.09.038.


Inhibition of protein kinase C alpha improves myocardial beta-adrenergic receptor signaling and ventricular function in a model of myocardial preservation.

D'Souza KM, Petrashevskaya NN, Merrill WH, Akhter SA.

J Thorac Cardiovasc Surg. 2008 Jan;135(1):172-9, 179.e1. doi: 10.1016/j.jtcvs.2007.08.035.


Beta-adrenergic receptor antagonism preserves myocardial function after brain death in a porcine model.

McLean KM, Pandalai PK, Pearl JM, Bulcao CF, Lyons JM, Wagner CJ, Akhter SA, Duffy JY.

J Heart Lung Transplant. 2007 May;26(5):522-8. Epub 2007 Mar 23.


Glucocorticoids alter the balance between pro- and anti-inflammatory mediators in the myocardium in a porcine model of brain death.

McLean KM, Duffy JY, Pandalai PK, Lyons JM, Bulcao CF, Wagner CJ, Akhter SA, Pearl JM.

J Heart Lung Transplant. 2007 Jan;26(1):78-84.


Restoration of myocardial beta-adrenergic receptor signaling after left ventricular assist device support.

Pandalai PK, Bulcao CF, Merrill WH, Akhter SA.

J Thorac Cardiovasc Surg. 2006 May;131(5):975-80.


Myocardial beta1-adrenergic receptor polymorphisms affect functional recovery after ischemic injury.

Akhter SA, D'Souza KM, Petrashevskaya NN, Mialet-Perez J, Liggett SB.

Am J Physiol Heart Circ Physiol. 2006 Apr;290(4):H1427-32.


Glucocorticoid administration reduces cardiac dysfunction after brain death in pigs.

Lyons JM, Pearl JM, McLean KM, Akhter SA, Wagner CJ, Pandalai PK, Duffy JY.

J Heart Lung Transplant. 2005 Dec;24(12):2249-54. Epub 2005 Nov 2.


The L-type calcium channel in the heart: the beat goes on.

Bodi I, Mikala G, Koch SE, Akhter SA, Schwartz A.

J Clin Invest. 2005 Dec;115(12):3306-17. Review.


Role of the beta-adrenergic receptor kinase in myocardial dysfunction after brain death.

Pandalai PK, Lyons JM, Duffy JY, McLean KM, Wagner CJ, Merrill WH, Pearl JM, Akhter SA.

J Thorac Cardiovasc Surg. 2005 Oct;130(4):1183-9.


Recurrent primary cardiac malignant fibrous histiocytoma following orthotopic heart transplantation.

Akhter SA, McGinty J, Konys JJ, Giesting RM, Merrill WH, Wagoner LE.

J Heart Lung Transplant. 2004 Dec;23(12):1447-50.


Simplified treatment of postoperative mediastinitis.

Merrill WH, Akhter SA, Wolf RK, Schneeberger EW, Flege JB Jr.

Ann Thorac Surg. 2004 Aug;78(2):608-12; discussion 608-12. Review.


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