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Items: 1 to 50 of 178

1.

Cardiomyocyte-Specific JunD Overexpression Increases Infarct Size following Ischemia/Reperfusion Cardiac Injury by Downregulating Sirt3.

Akhmedov A, Montecucco F, Costantino S, Vdovenko D, Schaub Clerigué A, Gaul DS, Burger F, Roth A, Carbone F, Liberale L, Amrollahi-Sharifabadi M, Vellone VG, Eriksson U, Matter CM, Crowe LA, Vallée JP, Paneni F, Vanhoutte PM, Camici GG, Mach F, Lüscher TF.

Thromb Haemost. 2020 Jan;120(1):168-180. doi: 10.1055/s-0039-3400299. Epub 2019 Dec 13.

PMID:
31858519
2.

Interleukin-1β Mediates Arterial Thrombus Formation via NET-Associated Tissue Factor.

Liberale L, Holy EW, Akhmedov A, Bonetti NR, Nietlispach F, Matter CM, Mach F, Montecucco F, Beer JH, Paneni F, Ruschitzka F, Libby P, Lüscher TF, Camici GG.

J Clin Med. 2019 Nov 26;8(12). pii: E2072. doi: 10.3390/jcm8122072.

3.

Endothelial SIRT6 blunts stroke size and neurological deficit by preserving blood-brain barrier integrity: a translational study.

Liberale L, Gaul DS, Akhmedov A, Bonetti NR, Nageswaran V, Costantino S, Pahla J, Weber J, Fehr V, Vdovenko D, Semerano A, Giacalone G, Kullak-Ublick GA, Sessa M, Eriksson U, Paneni F, Ruschitzka F, Montecucco F, Beer JH, Lüscher TF, Matter CM, Camici GG.

Eur Heart J. 2019 Oct 11. pii: ehz712. doi: 10.1093/eurheartj/ehz712. [Epub ahead of print]

PMID:
31603194
4.

Murine tissue factor disulfide mutation causes a bleeding phenotype with sex specific organ pathology and lethality.

Sluka SHM, Stämpfli SF, Akhmedov A, Klein-Rodewald T, Sanz-Moreno A, Horsch M, Grest P, Rothmeier AS, Rathkolb B, Schrewe A, Beckers J, Neff F, Wolf E, Camici GG, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Lüscher TF, Ruf W, Tanner FC.

Haematologica. 2019 Sep 5. pii: haematol.2019.218818. doi: 10.3324/haematol.2019.218818. [Epub ahead of print]

5.

Tumour Necrosis Factor-α Inhibition Improves Stroke Outcome in a Mouse Model of Rheumatoid Arthritis.

Bonetti NR, Diaz-Cañestro C, Liberale L, Crucet M, Akhmedov A, Merlini M, Reiner MF, Gobbato S, Stivala S, Kollias G, Ruschitzka F, Lüscher TF, Beer JH, Camici GG.

Sci Rep. 2019 Feb 18;9(1):2173. doi: 10.1038/s41598-019-38670-z.

6.

Obesity-induced activation of JunD promotes myocardial lipid accumulation and metabolic cardiomyopathy.

Costantino S, Akhmedov A, Melina G, Mohammed SA, Othman A, Ambrosini S, Wijnen WJ, Sada L, Ciavarella GM, Liberale L, Tanner FC, Matter CM, Hornemann T, Volpe M, Mechta-Grigoriou F, Camici GG, Sinatra R, Lüscher TF, Paneni F.

Eur Heart J. 2019 Mar 21;40(12):997-1008. doi: 10.1093/eurheartj/ehy903.

PMID:
30629164
7.

AP-1 (Activated Protein-1) Transcription Factor JunD Regulates Ischemia/Reperfusion Brain Damage via IL-1β (Interleukin-1β).

Diaz-Cañestro C, Reiner MF, Bonetti NR, Liberale L, Merlini M, Wüst P, Amstalden H, Briand-Schumacher S, Semerano A, Giacalone G, Sessa M, Beer JH, Akhmedov A, Lüscher TF, Camici GG.

Stroke. 2019 Feb;50(2):469-477. doi: 10.1161/STROKEAHA.118.023739.

PMID:
30626291
8.

Deleterious role of endothelial lectin-like oxidized low-density lipoprotein receptor-1 in ischaemia/reperfusion cerebral injury.

Akhmedov A, Bonetti NR, Reiner MF, Spescha RD, Amstalden H, Merlini M, Gaul DS, Diaz-Cañestro C, Briand-Schumacher S, Spescha RS, Semerano A, Giacalone G, Savarese G, Montecucco F, Kulic L, Nitsch RM, Matter CM, Kullak-Ublick GA, Sessa M, Lüscher TF, Beer JH, Liberale L, Camici GG.

J Cereb Blood Flow Metab. 2019 Nov;39(11):2233-2245. doi: 10.1177/0271678X18793266. Epub 2018 Aug 3. Erratum in: J Cereb Blood Flow Metab. 2019 Nov;39(11):NP1.

PMID:
30073881
9.

Corrigendum to 'Sirtuin 5 as a novel target to blunt blood-brain barrier damage induced by cerebral ischemia/reperfusion injury' [Int. J. Cardiol. 260 (2018) 148-155].

Diaz-Cañestro C, Merlini M, Bonetti NR, Liberale L, Wüst P, Briand-Schumacher S, Klohs J, Costantino S, Miranda M, Schoedon-Geiser G, Kullak-Ublick GA, Akhmedov A, Paneni F, Beer JH, Lüscher TF, Camici GG.

Int J Cardiol. 2018 Nov 15;271:405. doi: 10.1016/j.ijcard.2018.07.004. Epub 2018 Jul 13. No abstract available.

PMID:
30007483
10.

Post-ischaemic administration of the murine Canakinumab-surrogate antibody improves outcome in experimental stroke.

Liberale L, Diaz-Cañestro C, Bonetti NR, Paneni F, Akhmedov A, Beer JH, Montecucco F, Lüscher TF, Camici GG.

Eur Heart J. 2018 Oct 7;39(38):3511-3517. doi: 10.1093/eurheartj/ehy286.

PMID:
29788103
11.

Sirtuin 5 as a novel target to blunt blood-brain barrier damage induced by cerebral ischemia/reperfusion injury.

Diaz-Cañestro C, Merlini M, Bonetti NR, Liberale L, Wüst P, Briand-Schumacher S, Klohs J, Costantino S, Miranda M, Schoedon-Geiser G, Kullak-Ublick GA, Akhmedov A, Paneni F, Beer JH, Lüscher TF, Camici GG.

Int J Cardiol. 2018 Jun 1;260:148-155. doi: 10.1016/j.ijcard.2017.12.060. Erratum in: Int J Cardiol. 2018 Nov 15;271:405.

PMID:
29622432
12.

[Carotid endarterectomy in patients with symptomatic occlusions of the contralateral internal carotid artery].

Usachev DY, Lukshin VA, Shmigel'skiy AV, Akhmedov AD, Shul'gina AA.

Zh Vopr Neirokhir Im N N Burdenko. 2017;81(6):5-15. doi: 10.17116/neiro20178165-15. Russian.

13.

Cysteine-rich angiogenic inducer 61 (Cyr61): a novel soluble biomarker of acute myocardial injury improves risk stratification after acute coronary syndromes.

Klingenberg R, Aghlmandi S, Liebetrau C, Räber L, Gencer B, Nanchen D, Carballo D, Akhmedov A, Montecucco F, Zoller S, Brokopp C, Heg D, Jüni P, Marti Soler H, Marques-Vidal PM, Vollenweider P, Dörr O, Rodondi N, Mach F, Windecker S, Landmesser U, von Eckardstein A, Hamm CW, Matter CM, Lüscher TF.

Eur Heart J. 2017 Dec 14;38(47):3493-3502. doi: 10.1093/eurheartj/ehx640.

PMID:
29155984
14.

Interplay among H3K9-editing enzymes SUV39H1, JMJD2C and SRC-1 drives p66Shc transcription and vascular oxidative stress in obesity.

Costantino S, Paneni F, Virdis A, Hussain S, Mohammed SA, Capretti G, Akhmedov A, Dalgaard K, Chiandotto S, Pospisilik JA, Jenuwein T, Giorgio M, Volpe M, Taddei S, Lüscher TF, Cosentino F.

Eur Heart J. 2019 Jan 21;40(4):383-391. doi: 10.1093/eurheartj/ehx615.

PMID:
29077881
15.

[Simultaneous reconstruction of the carotid and vertebral arteries using a temporary intraluminal shunt (a clinical case)].

Usachev DY, Lukshin VA, Shevchenko EV, Shmigel'skiy AV, Sosnin AD, Akhmedov AD.

Zh Vopr Neirokhir Im N N Burdenko. 2017;81(5):76-83. doi: 10.17116/neiro201781576-83. Review. Russian.

16.

Tissue Factor Expression Does Not Predict Mortality in Breast Cancer Patients.

Stämpfli SF, Akhmedov A, Hausladen S, Varga Z, Dedes KJ, Hellermann J, Lüscher TF, Kristiansen G, Tanner FC, Breitenstein A.

Anticancer Res. 2017 Jun;37(6):3259-3264.

PMID:
28551673
17.

[Creation of extracranial-intracranial microvascular anastomosis under regional anesthesia (a case report and a review of the literature)].

Usachev DY, Lukshin VA, Shmigel'skiy AV, Akhmedov AD, Sosnin AD, Kozlova KA.

Zh Vopr Neirokhir Im N N Burdenko. 2017;81(2):88-95. doi: 10.17116/neiro201781288-94. Review. Russian.

18.

Endothelial LOX-1 activation differentially regulates arterial thrombus formation depending on oxLDL levels: role of the Oct-1/SIRT1 and ERK1/2 pathways.

Akhmedov A, Camici GG, Reiner MF, Bonetti NR, Costantino S, Holy EW, Spescha RD, Stivala S, Schaub Clerigué A, Speer T, Breitenstein A, Manz J, Lohmann C, Paneni F, Beer JH, Lüscher TF.

Cardiovasc Res. 2017 Apr 1;113(5):498-507. doi: 10.1093/cvr/cvx015.

PMID:
28199510
19.

Ticagrelor, but not clopidogrel, reduces arterial thrombosis via endothelial tissue factor suppression.

Reiner MF, Akhmedov A, Stivala S, Keller S, Gaul DS, Bonetti NR, Savarese G, Glanzmann M, Zhu C, Ruf W, Yang Z, Matter CM, Lüscher TF, Camici GG, Beer JH.

Cardiovasc Res. 2017 Jan;113(1):61-69. doi: 10.1093/cvr/cvw233. Epub 2016 Nov 15.

PMID:
28028070
20.

Reduced nitric oxide bioavailability mediates cerebroarterial dysfunction independent of cerebral amyloid angiopathy in a mouse model of Alzheimer's disease.

Merlini M, Shi Y, Keller S, Savarese G, Akhmedov A, Derungs R, Spescha RD, Kulic L, Nitsch RM, Lüscher TF, Camici GG.

Am J Physiol Heart Circ Physiol. 2017 Feb 1;312(2):H232-H238. doi: 10.1152/ajpheart.00607.2016. Epub 2016 Nov 11.

21.

[Perfusion criteria of the EICMA efficacy in patients with symptomatic occlusion of the internal carotid artery].

Lukshin VA, Usachev DY, Pronin IN, Akhmedov AD, Schultz EI.

Zh Vopr Neirokhir Im N N Burdenko. 2016;80(5):67-77. doi: 10.17116/neiro201680567-77. Russian.

22.

The MAP kinase JNK2 mediates cigarette smoke-induced arterial thrombosis.

Breitenstein A, Stämpfli SF, Reiner MF, Shi Y, Keller S, Akhmedov A, Schaub Clerigué A, Spescha RD, Beer HJ, Lüscher TF, Tanner FC, Camici GG.

Thromb Haemost. 2017 Jan 5;117(1):83-89. doi: 10.1160/TH16-05-0351. Epub 2016 Oct 20.

PMID:
27761579
23.

Carbamylated Low-Density Lipoproteins Induce a Prothrombotic State Via LOX-1: Impact on Arterial Thrombus Formation In Vivo.

Holy EW, Akhmedov A, Speer T, Camici GG, Zewinger S, Bonetti N, Beer JH, Lüscher TF, Tanner FC.

J Am Coll Cardiol. 2016 Oct 11;68(15):1664-1676. doi: 10.1016/j.jacc.2016.07.755.

24.

[An anastomosis between the internal carotid and vertebral arteries in the treatment of a patient with bilateral carotid arteries occlusions].

Usachev DY, Lukshin VA, Shmigel'skiy AV, Akhmedov AD.

Zh Vopr Neirokhir Im N N Burdenko. 2016;80(2):72-77. doi: 10.17116/neiro201680272-77. English, Russian.

25.

[Criteria of the efficacy of surgical brain revascularization in patients with chronic cerebral ischemia].

Lukshin VA, Usachev DY, Pronin IN, Shmigel'skiy AV, Akhmedov AD, Shevchenko EV.

Zh Vopr Neirokhir Im N N Burdenko. 2016;80(2):53-62. doi: 10.17116/neiro201680253-62. English, Russian.

26.

Mitochondrial dynamics and cell death in heart failure.

Marín-García J, Akhmedov AT.

Heart Fail Rev. 2016 Mar;21(2):123-36. doi: 10.1007/s10741-016-9530-2. Review.

PMID:
26872674
27.

[Combined surgical treatment of cavernous internal carotid artery pseudoaneurysm].

Usachev DY, Lukshin VA, Yakovlev SB, Kalinin PL, Sharipov OI, Kutin MA, Akhmedov AD, Bocharov AV, Aref'ev AM.

Zh Vopr Neirokhir Im N N Burdenko. 2016;80(5):116-123. doi: 10.17116/neiro2016805116-122. Russian.

28.

Molecular mechanism of endothelial and vascular aging: implications for cardiovascular disease.

Camici GG, Savarese G, Akhmedov A, Lüscher TF.

Eur Heart J. 2015 Dec 21;36(48):3392-403. doi: 10.1093/eurheartj/ehv587. Epub 2015 Nov 4. Review.

29.

Mitochondrial DNA maintenance: an appraisal.

Akhmedov AT, Marín-García J.

Mol Cell Biochem. 2015 Nov;409(1-2):283-305. doi: 10.1007/s11010-015-2532-x. Epub 2015 Aug 19. Review.

PMID:
26286847
30.

Circulating FABP4 is a prognostic biomarker in patients with acute coronary syndrome but not in asymptomatic individuals.

Reiser H, Klingenberg R, Hof D, Cooksley-Decasper S, Fuchs N, Akhmedov A, Zoller S, Marques-Vidal P, Marti Soler H, Heg D, Landmesser U, Rodondi N, Mach F, Windecker S, Vollenweider P, Matter CM, Lüscher TF, von Eckardstein A, Gawinecka J.

Arterioscler Thromb Vasc Biol. 2015 Aug;35(8):1872-9. doi: 10.1161/ATVBAHA.115.305365. Epub 2015 Jun 11.

31.

Post-ischaemic silencing of p66Shc reduces ischaemia/reperfusion brain injury and its expression correlates to clinical outcome in stroke.

Spescha RD, Klohs J, Semerano A, Giacalone G, Derungs RS, Reiner MF, Rodriguez Gutierrez D, Mendez-Carmona N, Glanzmann M, Savarese G, Kränkel N, Akhmedov A, Keller S, Mocharla P, Kaufmann MR, Wenger RH, Vogel J, Kulic L, Nitsch RM, Beer JH, Peruzzotti-Jametti L, Sessa M, Lüscher TF, Camici GG.

Eur Heart J. 2015 Jul 1;36(25):1590-600. doi: 10.1093/eurheartj/ehv140. Epub 2015 Apr 22.

32.

Epigenetics of the failing heart.

Marín-García J, Akhmedov AT.

Heart Fail Rev. 2015 Jul;20(4):435-59. doi: 10.1007/s10741-015-9483-x. Review.

PMID:
25847519
33.

[Surgical management of patients with pathological deformities of carotid arteries].

Usachev DY, Lukshin VA, Sosnin AD, Shishkina LV, Shimgel'skii AV, Nagorskaya IA, Vasil'chenko VV, Belyaev AY, Akhmedov AD, Batishcheva EV.

Zh Vopr Neirokhir Im N N Burdenko. 2014;78(5):3-15; discussion 15. English, Russian.

34.

Genetic deletion of the adaptor protein p66Shc increases susceptibility to short-term ischaemic myocardial injury via intracellular salvage pathways.

Akhmedov A, Montecucco F, Braunersreuther V, Camici GG, Jakob P, Reiner MF, Glanzmann M, Burger F, Paneni F, Galan K, Pelli G, Vuilleumier N, Belin A, Vallée JP, Mach F, Lüscher TF.

Eur Heart J. 2015 Feb 21;36(8):516-26a. doi: 10.1093/eurheartj/ehu400. Epub 2014 Oct 21.

35.

Mitochondrial oxidative metabolism and uncoupling proteins in the failing heart.

Akhmedov AT, Rybin V, Marín-García J.

Heart Fail Rev. 2015 Mar;20(2):227-49. doi: 10.1007/s10741-014-9457-4. Review.

PMID:
25192828
36.

Calsyntenin-1 regulates targeting of dendritic NMDA receptors and dendritic spine maturation in CA1 hippocampal pyramidal cells during postnatal development.

Ster J, Steuble M, Orlando C, Diep TM, Akhmedov A, Raineteau O, Pernet V, Sonderegger P, Gerber U.

J Neurosci. 2014 Jun 25;34(26):8716-27. doi: 10.1523/JNEUROSCI.0144-14.2014.

37.

Alternatively spliced tissue factor is not sufficient for embryonic development.

Sluka SH, Akhmedov A, Vogel J, Unruh D, Bogdanov VY, Camici GG, Lüscher TF, Ruf W, Tanner FC.

PLoS One. 2014 May 30;9(5):e97793. doi: 10.1371/journal.pone.0097793. eCollection 2014.

38.

Adaptor protein p66(Shc) mediates hypertension-associated, cyclic stretch-dependent, endothelial damage.

Spescha RD, Glanzmann M, Simic B, Witassek F, Keller S, Akhmedov A, Tanner FC, Lüscher TF, Camici GG.

Hypertension. 2014 Aug;64(2):347-53. doi: 10.1161/HYPERTENSIONAHA.113.02129. Epub 2014 May 19.

39.

Carbamylated low-density lipoprotein induces endothelial dysfunction.

Speer T, Owala FO, Holy EW, Zewinger S, Frenzel FL, Stähli BE, Razavi M, Triem S, Cvija H, Rohrer L, Seiler S, Heine GH, Jankowski V, Jankowski J, Camici GG, Akhmedov A, Fliser D, Lüscher TF, Tanner FC.

Eur Heart J. 2014 Nov 14;35(43):3021-32. doi: 10.1093/eurheartj/ehu111. Epub 2014 Mar 21.

40.

[The case of simultaneous use of direct and endovascular techniques for the reconstruction of occluded brachiocephalic trunk].

Usachev DIu, Lukshin VA, Iakovlev SB, Arustamian SR, Shmigel'skiĭ AV, Akhmedov AD.

Zh Vopr Neirokhir Im N N Burdenko. 2013;77(6):39-44. English, Russian.

41.

Endothelial overexpression of LOX-1 increases plaque formation and promotes atherosclerosis in vivo.

Akhmedov A, Rozenberg I, Paneni F, Camici GG, Shi Y, Doerries C, Sledzinska A, Mocharla P, Breitenstein A, Lohmann C, Stein S, von Lukowicz T, Kurrer MO, Borén J, Becher B, Tanner FC, Landmesser U, Matter CM, Lüscher TF.

Eur Heart J. 2014 Oct 21;35(40):2839-48. doi: 10.1093/eurheartj/eht532. Epub 2014 Jan 12.

42.

[Carotid endarterectomy in patients with high surgical risk].

Akhmedov AD, Usachev DIu, Lukchin VA, Shmigel'skiĭ AV, Beliaev AIu, Sosnin AD.

Zh Vopr Neirokhir Im N N Burdenko. 2013;77(4):36-41; discussion 41-2. English, Russian.

43.

PI3K/p110α inhibition selectively interferes with arterial thrombosis and neointima formation, but not re-endothelialization: potential implications for drug-eluting stent design.

Holy EW, Jakob P, Eickner T, Camici GG, Beer JH, Akhmedov A, Sternberg K, Schmitz KP, Lüscher TF, Tanner FC.

Eur Heart J. 2014 Mar;35(12):808-20. doi: 10.1093/eurheartj/eht496. Epub 2013 Dec 11.

PMID:
24334406
44.

The AP-1 transcription factor c-Jun prevents stress-imposed maladaptive remodeling of the heart.

Windak R, Müller J, Felley A, Akhmedov A, Wagner EF, Pedrazzini T, Sumara G, Ricci R.

PLoS One. 2013 Sep 10;8(9):e73294. doi: 10.1371/journal.pone.0073294. eCollection 2013.

45.

p27(Kip1) inhibits tissue factor expression.

Breitenstein A, Akhmedov A, Camici GG, Lüscher TF, Tanner FC.

Biochem Biophys Res Commun. 2013 Oct 4;439(4):559-63. doi: 10.1016/j.bbrc.2013.09.002. Epub 2013 Sep 8.

PMID:
24021283
46.

[Surgical treatment of patients with chronic cerebral ischemia due to occlusion of the common carotid arteries].

Usachev DIu, Lukshin VA, Pronin IN, Shmigel'siĭ AV, Beliaev AIu, Sosnin AD, Akhmedov AD.

Zh Vopr Neirokhir Im N N Burdenko. 2013;77(3):27-35; discussion 35. English, Russian.

47.

Caffeic acid phenethyl ester inhibits endothelial tissue factor expression.

Gebhard C, Stähli BE, Largiadèr S, Holy EW, Akhmedov A, Camici GG, Lüscher TF, Tanner FC.

Biol Pharm Bull. 2013;36(6):1032-5.

48.

Foreign body penetrations of hand and wrist: a retrospective study.

Hocaoğlu E, Kuvat SV, Özalp B, Akhmedov A, Doğan Y, Kozanoğlu E, Mete FS, Erer M.

Ulus Travma Acil Cerrahi Derg. 2013 Jan;19(1):58-64. doi: 10.5505/tjtes.2013.04453.

49.

Abnormal high-density lipoprotein induces endothelial dysfunction via activation of Toll-like receptor-2.

Speer T, Rohrer L, Blyszczuk P, Shroff R, Kuschnerus K, Kränkel N, Kania G, Zewinger S, Akhmedov A, Shi Y, Martin T, Perisa D, Winnik S, Müller MF, Sester U, Wernicke G, Jung A, Gutteck U, Eriksson U, Geisel J, Deanfield J, von Eckardstein A, Lüscher TF, Fliser D, Bahlmann FH, Landmesser U.

Immunity. 2013 Apr 18;38(4):754-68. doi: 10.1016/j.immuni.2013.02.009. Epub 2013 Mar 7.

50.

Deletion of the activated protein-1 transcription factor JunD induces oxidative stress and accelerates age-related endothelial dysfunction.

Paneni F, Osto E, Costantino S, Mateescu B, Briand S, Coppolino G, Perna E, Mocharla P, Akhmedov A, Kubant R, Rohrer L, Malinski T, Camici GG, Matter CM, Mechta-Grigoriou F, Volpe M, Lüscher TF, Cosentino F.

Circulation. 2013 Mar 19;127(11):1229-40, e1-21. doi: 10.1161/CIRCULATIONAHA.112.000826. Epub 2013 Feb 14.

PMID:
23410942

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