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Items: 37


Suppression of Alternative Lipooligosaccharide Glycosyltransferase Activity by UDP-Galactose Epimerase Enhances Murine Lung Infection and Evasion of Serum IgM.

Wong SM, Jackson MD, Akerley BJ.

Front Cell Infect Microbiol. 2019 May 15;9:160. doi: 10.3389/fcimb.2019.00160. eCollection 2019.


Recognition of conserved antigens by Th17 cells provides broad protection against pulmonary Haemophilus influenzae infection.

Li W, Zhang X, Yang Y, Yin Q, Wang Y, Li Y, Wang C, Wong SM, Wang Y, Goldfine H, Akerley BJ, Shen H.

Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):E7149-E7157. doi: 10.1073/pnas.1802261115. Epub 2018 Jul 9.


No-Go Zones for Mariner Transposition.

Akerley BJ.

MBio. 2016 Oct 11;7(5). pii: e01690-16. doi: 10.1128/mBio.01690-16.


Defining the Binding Region in Factor H to Develop a Therapeutic Factor H-Fc Fusion Protein against Non-Typeable Haemophilus influenzae.

Wong SM, Shaughnessy J, Ram S, Akerley BJ.

Front Cell Infect Microbiol. 2016 Apr 13;6:40. doi: 10.3389/fcimb.2016.00040. eCollection 2016.


Outer membrane protein P5 is required for resistance of nontypeable Haemophilus influenzae to both the classical and alternative complement pathways.

Rosadini CV, Ram S, Akerley BJ.

Infect Immun. 2014 Feb;82(2):640-9. doi: 10.1128/IAI.01224-13. Epub 2013 Nov 25.


Genome-wide fitness profiling reveals adaptations required by Haemophilus in coinfection with influenza A virus in the murine lung.

Wong SM, Bernui M, Shen H, Akerley BJ.

Proc Natl Acad Sci U S A. 2013 Sep 17;110(38):15413-8. doi: 10.1073/pnas.1311217110. Epub 2013 Sep 3.


Genome-scale approaches to identify genes essential for Haemophilus influenzae pathogenesis.

Wong SM, Akerley BJ.

Front Cell Infect Microbiol. 2012 Mar 5;2:23. doi: 10.3389/fcimb.2012.00023. eCollection 2012. Review.


High-resolution phenotypic profiling defines genes essential for mycobacterial growth and cholesterol catabolism.

Griffin JE, Gawronski JD, Dejesus MA, Ioerger TR, Akerley BJ, Sassetti CM.

PLoS Pathog. 2011 Sep;7(9):e1002251. doi: 10.1371/journal.ppat.1002251. Epub 2011 Sep 29.


A novel zinc binding system, ZevAB, is critical for survival of nontypeable Haemophilus influenzae in a murine lung infection model.

Rosadini CV, Gawronski JD, Raimunda D, Arg├╝ello JM, Akerley BJ.

Infect Immun. 2011 Aug;79(8):3366-76. doi: 10.1128/IAI.05135-11. Epub 2011 May 16.


High-throughput insertion tracking by deep sequencing for the analysis of bacterial pathogens.

Wong SM, Gawronski JD, Lapointe D, Akerley BJ.

Methods Mol Biol. 2011;733:209-22. doi: 10.1007/978-1-61779-089-8_15.


ArcA-regulated glycosyltransferase lic2B promotes complement evasion and pathogenesis of nontypeable Haemophilus influenzae.

Wong SM, St Michael F, Cox A, Ram S, Akerley BJ.

Infect Immun. 2011 May;79(5):1971-83. doi: 10.1128/IAI.01269-10. Epub 2011 Feb 28.


Tracking insertion mutants within libraries by deep sequencing and a genome-wide screen for Haemophilus genes required in the lung.

Gawronski JD, Wong SM, Giannoukos G, Ward DV, Akerley BJ.

Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16422-7. doi: 10.1073/pnas.0906627106. Epub 2009 Sep 4.


Resistance of Haemophilus influenzae to reactive nitrogen donors and gamma interferon-stimulated macrophages requires the formate-dependent nitrite reductase regulator-activated ytfE gene.

Harrington JC, Wong SM, Rosadini CV, Garifulin O, Boyartchuk V, Akerley BJ.

Infect Immun. 2009 May;77(5):1945-58. doi: 10.1128/IAI.01365-08. Epub 2009 Mar 16.


Structure of YraM, a protein essential for growth of Haemophilus influenzae.

Vijayalakshmi J, Akerley BJ, Saper MA.

Proteins. 2008 Oct;73(1):204-17. doi: 10.1002/prot.22033.


Identification and analysis of essential genes in Haemophilus influenzae.

Wong SM, Akerley BJ.

Methods Mol Biol. 2008;416:27-44. doi: 10.1007/978-1-59745-321-9_3. Review.


The periplasmic disulfide oxidoreductase DsbA contributes to Haemophilus influenzae pathogenesis.

Rosadini CV, Wong SM, Akerley BJ.

Infect Immun. 2008 Apr;76(4):1498-508. doi: 10.1128/IAI.01378-07. Epub 2008 Jan 22.


The ArcA regulon and oxidative stress resistance in Haemophilus influenzae.

Wong SM, Alugupalli KR, Ram S, Akerley BJ.

Mol Microbiol. 2007 Jun;64(5):1375-90.


In Silico Metabolic Model and Protein Expression of Haemophilus influenzae Strain Rd KW20 in Rich Medium.

Raghunathan A, Price ND, Galperin MY, Makarova KS, Purvine S, Picone AF, Cherny T, Xie T, Reilly TJ, Munson R Jr, Tyler RE, Akerley BJ, Smith AL, Palsson BO, Kolker E.

OMICS. 2004 Spring;8(1):25-41.


H. influenzae Consortium: integrative study of H. influenzae-human interactions.

Kolker E, Purvine S, Picone A, Cherny T, Akerley BJ, Munson RS Jr, Palsson BO, Daines DA, Smith AL.

OMICS. 2002;6(4):341-8.


Analysis of gene function in bacterial pathogens by GAMBIT.

Akerley BJ, Lampe DJ.

Methods Enzymol. 2002;358:100-8. No abstract available.


A genome-scale analysis for identification of genes required for growth or survival of Haemophilus influenzae.

Akerley BJ, Rubin EJ, Novick VL, Amaya K, Judson N, Mekalanos JJ.

Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):966-71.


Redox signal transduction by the ArcB sensor kinase of Haemophilus influenzae lacking the PAS domain.

Georgellis D, Kwon O, Lin EC, Wong SM, Akerley BJ.

J Bacteriol. 2001 Dec;183(24):7206-12.


Presence of the Cpx system in bacteria.

De Wulf P, Akerley BJ, Lin EC.

Microbiology. 2000 Feb;146 ( Pt 2):247-8. No abstract available.


Hyperactive transposase mutants of the Himar1 mariner transposon.

Lampe DJ, Akerley BJ, Rubin EJ, Mekalanos JJ, Robertson HM.

Proc Natl Acad Sci U S A. 1999 Sep 28;96(20):11428-33.


In vivo transposition of mariner-based elements in enteric bacteria and mycobacteria.

Rubin EJ, Akerley BJ, Novik VN, Lampe DJ, Husson RN, Mekalanos JJ.

Proc Natl Acad Sci U S A. 1999 Feb 16;96(4):1645-50.


Filamentous hemagglutinin of Bordetella bronchiseptica is required for efficient establishment of tracheal colonization.

Cotter PA, Yuk MH, Mattoo S, Akerley BJ, Boschwitz J, Relman DA, Miller JF.

Infect Immun. 1998 Dec;66(12):5921-9.


Systematic identification of essential genes by in vitro mariner mutagenesis.

Akerley BJ, Rubin EJ, Camilli A, Lampe DJ, Robertson HM, Mekalanos JJ.

Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8927-32.


Neither the Bvg- phase nor the vrg6 locus of Bordetella pertussis is required for respiratory infection in mice.

Martinez de Tejada G, Cotter PA, Heininger U, Camilli A, Akerley BJ, Mekalanos JJ, Miller JF.

Infect Immun. 1998 Jun;66(6):2762-8.


Understanding signal transduction during bacterial infection.

Akerley BJ, Miller JF.

Trends Microbiol. 1996 Apr;4(4):141-6. Review.


bvg Repression of alcaligin synthesis in Bordetella bronchiseptica is associated with phylogenetic lineage.

Giardina PC, Foster LA, Musser JM, Akerley BJ, Miller JF, Dyer DW.

J Bacteriol. 1995 Nov;177(21):6058-63.


The bvgAS locus negatively controls motility and synthesis of flagella in Bordetella bronchiseptica.

Akerley BJ, Monack DM, Falkow S, Miller JF.

J Bacteriol. 1992 Feb;174(3):980-90.

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