Sort by
Items per page

Send to

Choose Destination

Search results

Items: 13


A microRNA/Runx1/Runx2 network regulates prostate tumor progression from onset to adenocarcinoma in TRAMP mice.

Farina NH, Zingiryan A, Akech JA, Callahan CJ, Lu H, Stein JL, Languino LR, Stein GS, Lian JB.

Oncotarget. 2016 Oct 25;7(43):70462-70474. doi: 10.18632/oncotarget.11992.


The SWI/SNF ATPases Are Required for Triple Negative Breast Cancer Cell Proliferation.

Wu Q, Madany P, Akech J, Dobson JR, Douthwright S, Browne G, Colby JL, Winter GE, Bradner JE, Pratap J, Sluder G, Bhargava R, Chiosea SI, van Wijnen AJ, Stein JL, Stein GS, Lian JB, Nickerson JA, Imbalzano AN.

J Cell Physiol. 2015 Nov;230(11):2683-94. doi: 10.1002/jcp.24991.


Expression of the IL-11 Gene in Metastatic Cells Is Supported by Runx2-Smad and Runx2-cJun Complexes Induced by TGFβ1.

Zhang X, Wu H, Dobson JR, Browne G, Hong D, Akech J, Languino LR, Stein GS, Lian JB.

J Cell Biochem. 2015 Sep;116(9):2098-108. doi: 10.1002/jcb.25167.


Targeting of Runx2 by miR-135 and miR-203 Impairs Progression of Breast Cancer and Metastatic Bone Disease.

Taipaleenmäki H, Browne G, Akech J, Zustin J, van Wijnen AJ, Stein JL, Hesse E, Stein GS, Lian JB.

Cancer Res. 2015 Apr 1;75(7):1433-44. doi: 10.1158/0008-5472.CAN-14-1026. Epub 2015 Jan 29.


Runx2-Smad signaling impacts the progression of tumor-induced bone disease.

Zhang X, Akech J, Browne G, Russell S, Wixted JJ, Stein JL, Stein GS, Lian JB.

Int J Cancer. 2015 Mar 15;136(6):1321-32. doi: 10.1002/ijc.29094. Epub 2014 Aug 5.


Integrin αvβ6 promotes an osteolytic program in cancer cells by upregulating MMP2.

Dutta A, Li J, Lu H, Akech J, Pratap J, Wang T, Zerlanko BJ, FitzGerald TJ, Jiang Z, Birbe R, Wixted J, Violette SM, Stein JL, Stein GS, Lian JB, Languino LR.

Cancer Res. 2014 Mar 1;74(5):1598-608. doi: 10.1158/0008-5472.CAN-13-1796. Epub 2014 Jan 2.


Genomic promoter occupancy of runt-related transcription factor RUNX2 in Osteosarcoma cells identifies genes involved in cell adhesion and motility.

van der Deen M, Akech J, Lapointe D, Gupta S, Young DW, Montecino MA, Galindo M, Lian JB, Stein JL, Stein GS, van Wijnen AJ.

J Biol Chem. 2012 Feb 10;287(7):4503-17. doi: 10.1074/jbc.M111.287771. Epub 2011 Dec 9.


The histone deacetylase inhibitor, vorinostat, reduces tumor growth at the metastatic bone site and associated osteolysis, but promotes normal bone loss.

Pratap J, Akech J, Wixted JJ, Szabo G, Hussain S, McGee-Lawrence ME, Li X, Bedard K, Dhillon RJ, van Wijnen AJ, Stein JL, Stein GS, Westendorf JJ, Lian JB.

Mol Cancer Ther. 2010 Dec;9(12):3210-20. doi: 10.1158/1535-7163.MCT-10-0572.


The cancer-related Runx2 protein enhances cell growth and responses to androgen and TGFbeta in prostate cancer cells.

van der Deen M, Akech J, Wang T, FitzGerald TJ, Altieri DC, Languino LR, Lian JB, van Wijnen AJ, Stein JL, Stein GS.

J Cell Biochem. 2010 Mar 1;109(4):828-37. doi: 10.1002/jcb.22463.


Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions.

Akech J, Wixted JJ, Bedard K, van der Deen M, Hussain S, Guise TA, van Wijnen AJ, Stein JL, Languino LR, Altieri DC, Pratap J, Keller E, Stein GS, Lian JB.

Oncogene. 2010 Feb 11;29(6):811-21. doi: 10.1038/onc.2009.389. Epub 2009 Nov 16.


Ectopic runx2 expression in mammary epithelial cells disrupts formation of normal acini structure: implications for breast cancer progression.

Pratap J, Imbalzano KM, Underwood JM, Cohet N, Gokul K, Akech J, van Wijnen AJ, Stein JL, Imbalzano AN, Nickerson JA, Lian JB, Stein GS.

Cancer Res. 2009 Sep 1;69(17):6807-14. doi: 10.1158/0008-5472.CAN-09-1471. Epub 2009 Aug 18.


Differential expression of cholinephosphotransferase in normal and cancerous human mammary epithelial cells.

Ghosh A, Akech J, Mukherjee S, Das SK.

Biochem Biophys Res Commun. 2002 Oct 4;297(4):1043-8.


Supplemental Content

Support Center