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Items: 24

1.

The discovery of novel 3-aryl-indazole derivatives as peripherally restricted pan-Trk inhibitors for the treatment of pain.

Shirahashi H, Toriihara E, Suenaga Y, Yoshida H, Akaogi K, Endou Y, Wakabayashi M, Takashima M.

Bioorg Med Chem Lett. 2019 Aug 15;29(16):2320-2326. doi: 10.1016/j.bmcl.2019.06.018. Epub 2019 Jun 17.

PMID:
31235262
2.

Estrogen Exhibits a Biphasic Effect on Prostate Tumor Growth through the Estrogen Receptor β-KLF5 Pathway.

Nakajima Y, Osakabe A, Waku T, Suzuki T, Akaogi K, Fujimura T, Homma Y, Inoue S, Yanagisawa J.

Mol Cell Biol. 2015 Oct 19;36(1):144-56. doi: 10.1128/MCB.00625-15. Print 2016 Jan 1.

3.

A tangible head model showing semicircular canals for demonstrating the physical treatment for BPPV.

Fujisaka M, Akaogi K, Shojaku H.

Acta Otolaryngol. 2015;135(12):1212-8. doi: 10.3109/00016489.2015.1064546. Epub 2015 Aug 14.

PMID:
26271968
4.

The nucleolar protein Myb-binding protein 1A (MYBBP1A) enhances p53 tetramerization and acetylation in response to nucleolar disruption.

Ono W, Hayashi Y, Yokoyama W, Kuroda T, Kishimoto H, Ito I, Kimura K, Akaogi K, Waku T, Yanagisawa J.

J Biol Chem. 2014 Feb 21;289(8):4928-40. doi: 10.1074/jbc.M113.474049. Epub 2013 Dec 27.

5.

Nucleolar protein, Myb-binding protein 1A, specifically binds to nonacetylated p53 and efficiently promotes transcriptional activation.

Ono W, Akaogi K, Waku T, Kuroda T, Yokoyama W, Hayashi Y, Kimura K, Kishimoto H, Yanagisawa J.

Biochem Biophys Res Commun. 2013 May 10;434(3):659-63. doi: 10.1016/j.bbrc.2013.04.006. Epub 2013 Apr 11.

PMID:
23583237
6.

MYBBP1A suppresses breast cancer tumorigenesis by enhancing the p53 dependent anoikis.

Akaogi K, Ono W, Hayashi Y, Kishimoto H, Yanagisawa J.

BMC Cancer. 2013 Feb 7;13:65. doi: 10.1186/1471-2407-13-65.

7.

Estrogen regulates tumor growth through a nonclassical pathway that includes the transcription factors ERβ and KLF5.

Nakajima Y, Akaogi K, Suzuki T, Osakabe A, Yamaguchi C, Sunahara N, Ishida J, Kako K, Ogawa S, Fujimura T, Homma Y, Fukamizu A, Murayama A, Kimura K, Inoue S, Yanagisawa J.

Sci Signal. 2011 Apr 12;4(168):ra22. doi: 10.1126/scisignal.2001551.

8.

KLF4 suppresses estrogen-dependent breast cancer growth by inhibiting the transcriptional activity of ERalpha.

Akaogi K, Nakajima Y, Ito I, Kawasaki S, Oie SH, Murayama A, Kimura K, Yanagisawa J.

Oncogene. 2009 Aug 13;28(32):2894-902. doi: 10.1038/onc.2009.151. Epub 2009 Jun 8.

PMID:
19503094
9.

PPARgamma ligands suppress the feedback loop between E2F2 and cyclin-E1.

Komatsu Y, Ito I, Wayama M, Fujimura A, Akaogi K, Machida H, Nakajima Y, Kuroda T, Ohmori K, Murayama A, Kimura K, Yanagisawa J.

Biochem Biophys Res Commun. 2008 May 23;370(1):145-8. doi: 10.1016/j.bbrc.2008.03.046. Epub 2008 Mar 18.

PMID:
18355447
10.

PSK and OK-432-induced immunomodulation of inducible nitric oxide (NO) synthase gene expression in mouse peritoneal polymorphonuclear leukocytes and NO-mediated cytotoxicity.

Asai K, Kato H, Hirose K, Akaogi K, Kimura S, Mukai S, Inoue M, Yamamura Y, Sano H, Sugino S, Yoshikawa T, Kondo M.

Immunopharmacol Immunotoxicol. 2000 May;22(2):221-35.

PMID:
10952028
11.

Identification of cell-binding site of angiomodulin (AGM/TAF/Mac25) that interacts with heparan sulfates on cell surface.

Sato J, Hasegawa S, Akaogi K, Yasumitsu H, Yamada S, Sugahara K, Miyazaki K.

J Cell Biochem. 1999 Nov 1;75(2):187-95.

PMID:
10502291
12.

Role of interleukin-6 in uncoupling of bone in vivo in a human squamous carcinoma coproducing parathyroid hormone-related peptide and interleukin-6.

Nagai Y, Yamato H, Akaogi K, Hirose K, Ueyama Y, Ikeda K, Matsumoto T, Fujita T, Ogata E.

J Bone Miner Res. 1998 Apr;13(4):664-72.

13.

Synergistic growth stimulation of mouse fibroblasts by tumor-derived adhesion factor with insulin-like growth factors and insulin.

Akaogi K, Sato J, Okabe Y, Sakamoto Y, Yasumitsu H, Miyazaki K.

Cell Growth Differ. 1996 Dec;7(12):1671-7.

14.

Specific accumulation of tumor-derived adhesion factor in tumor blood vessels and in capillary tube-like structures of cultured vascular endothelial cells.

Akaogi K, Okabe Y, Sato J, Nagashima Y, Yasumitsu H, Sugahara K, Miyazaki K.

Proc Natl Acad Sci U S A. 1996 Aug 6;93(16):8384-9.

15.

Induction of gene expression for nitric oxide synthase by immunomodulating drugs in the RAW264.7 murine macrophage cell line.

Asai K, Kato H, Kimura S, Mukai S, Kawahito Y, Sano H, Kondo M, Akaogi K, Hirose K.

Cancer Immunol Immunother. 1996 Jun;42(5):275-9.

PMID:
8706048
16.

Stimulation of endothelial cell migration in culture by ladsin, a laminin-5-like cell adhesion protein.

Kikkawa Y, Akaogi K, Mizushima H, Yamanaka N, Umeda M, Miyazaki K.

In Vitro Cell Dev Biol Anim. 1996 Jan;32(1):46-52.

PMID:
8835318
17.
18.

Zonal organization of climbing fiber projections to the nodulus in the cat.

Akaogi K, Sato Y, Ikarashi K, Kawasaki T.

Brain Res. 1994 Feb 28;638(1-2):1-11.

PMID:
7515316
19.

Cell adhesion activity of a 30-kDa major secreted protein from human bladder carcinoma cells.

Akaogi K, Okabe Y, Funahashi K, Yoshitake Y, Nishikawa K, Yasumitsu H, Umeda M, Miyazaki K.

Biochem Biophys Res Commun. 1994 Feb 15;198(3):1046-53.

PMID:
8117260
20.

[Afferent projections to the nodulus in the cat. II. Mossy fiber projections].

Akaogi K.

Nihon Jibiinkoka Gakkai Kaiho. 1994 Jan;97(1):12-9. Japanese.

PMID:
8176532
21.

[Afferent projections to the nodulus in the cat. I. Climbing fiber projections].

Akaogi K.

Nihon Jibiinkoka Gakkai Kaiho. 1994 Jan;97(1):1-11. Japanese.

PMID:
8176530
22.

Purification and characterization of a two-chain form of tissue inhibitor of metalloproteinases (TIMP) type 2 and a low molecular weight TIMP-like protein.

Miyazaki K, Funahashi K, Numata Y, Koshikawa N, Akaogi K, Kikkawa Y, Yasumitsu H, Umeda M.

J Biol Chem. 1993 Jul 5;268(19):14387-93.

23.

Effect of 24R,25-dihydroxyvitamin D3 on the formation and function of osteoclastic cells.

Yamato H, Okazaki R, Ishii T, Ogata E, Sato T, Kumegawa M, Akaogi K, Taniguchi N, Matsumoto T.

Calcif Tissue Int. 1993 Mar;52(3):255-60.

PMID:
8481842
24.

Nucleotide sequence of a full-length cDNA for 90 kDa heat-shock protein from human peripheral blood lymphocytes.

Yamazaki M, Akaogi K, Miwa T, Imai T, Soeda E, Yokoyama K.

Nucleic Acids Res. 1989 Sep 12;17(17):7108. No abstract available.

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