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Items: 1 to 50 of 113

1.

Efficacy of a novel phosphodiesterase inhibitor, E6005, in patients with atopic dermatitis: An investigator-blinded, vehicle-controlled study.

Ohba F, Matsuki S, Imayama S, Matsuguma K, Hojo S, Nomoto M, Akama H.

J Dermatolog Treat. 2016 Oct;27(5):467-72. doi: 10.3109/09546634.2016.1157257. Epub 2016 Apr 14.

PMID:
27080209
2.

Safety, tolerability and pharmacokinetics of a novel phosphodiesterase inhibitor, E6005 ointment, in healthy volunteers and in patients with atopic dermatitis.

Ohba F, Nomoto M, Hojo S, Akama H.

J Dermatolog Treat. 2016;27(3):241-6. doi: 10.3109/09546634.2015.1093587. Epub 2015 Nov 18.

PMID:
26581111
3.

Using Graph Components Derived from an Associative Concept Dictionary to Predict fMRI Neural Activation Patterns that Represent the Meaning of Nouns.

Akama H, Miyake M, Jung J, Murphy B.

PLoS One. 2015 Apr 30;10(4):e0125725. doi: 10.1371/journal.pone.0125725. eCollection 2015.

4.

Neural basis of language switching in the brain: fMRI evidence from Korean-Chinese early bilinguals.

Lei M, Akama H, Murphy B.

Brain Lang. 2014 Nov;138:12-8. doi: 10.1016/j.bandl.2014.08.009. Epub 2014 Sep 29.

5.

Safety and efficacy of topical E6005, a phosphodiesterase 4 inhibitor, in Japanese adult patients with atopic dermatitis: results of a randomized, vehicle-controlled, multicenter clinical trial.

Furue M, Kitahara Y, Akama H, Hojo S, Hayashi N, Nakagawa H; JAPANESE E6005 Study Investigators.

J Dermatol. 2014 Jul;41(7):577-85. doi: 10.1111/1346-8138.12534. Epub 2014 Jun 18.

PMID:
24942594
6.

Recovery of clinical but not radiographic outcomes by the delayed addition of adalimumab to methotrexate-treated Japanese patients with early rheumatoid arthritis: 52-week results of the HOPEFUL-1 trial.

Yamanaka H, Ishiguro N, Takeuchi T, Miyasaka N, Mukai M, Matsubara T, Uchida S, Akama H, Kupper H, Arora V, Tanaka Y.

Rheumatology (Oxford). 2014 May;53(5):904-13. doi: 10.1093/rheumatology/ket465. Epub 2014 Jan 17.

7.

A microliter-scale high-throughput screening system with quantum-dot nanoprobes for amyloid-β aggregation inhibitors.

Ishigaki Y, Tanaka H, Akama H, Ogara T, Uwai K, Tokuraku K.

PLoS One. 2013 Aug 26;8(8):e72992. doi: 10.1371/journal.pone.0072992. eCollection 2013.

8.

Adalimumab, a human anti-TNF monoclonal antibody, outcome study for the prevention of joint damage in Japanese patients with early rheumatoid arthritis: the HOPEFUL 1 study.

Takeuchi T, Yamanaka H, Ishiguro N, Miyasaka N, Mukai M, Matsubara T, Uchida S, Akama H, Kupper H, Arora V, Tanaka Y.

Ann Rheum Dis. 2014 Mar;73(3):536-43. doi: 10.1136/annrheumdis-2012-202433. Epub 2013 Jan 11.

9.

Decoding semantics across fMRI sessions with different stimulus modalities: a practical MVPA study.

Akama H, Murphy B, Na L, Shimizu Y, Poesio M.

Front Neuroinform. 2012 Aug 24;6:24. doi: 10.3389/fninf.2012.00024. eCollection 2012.

10.

[Topics of glucocorticoids--centered on therapy for rheumatoid arthritis].

Akama H.

Nihon Rinsho Meneki Gakkai Kaishi. 2011;34(6):464-75. Review. Japanese.

11.

Development of an immunochromatographic strip for simple detection of penicillin-binding protein 2'.

Matsui H, Hanaki H, Inoue M, Akama H, Nakae T, Sunakawa K, Omura S.

Clin Vaccine Immunol. 2011 Feb;18(2):248-53. doi: 10.1128/CVI.00252-10. Epub 2010 Dec 22.

12.

[RANKL inhibition as therapy for joint damage].

Akama H.

Nihon Rinsho Meneki Gakkai Kaishi. 2007 Oct;30(5):404-7. Review. Japanese.

13.

Trends of beta-lactam antibiotic susceptibility in blood-borne methicillin-resistant Staphylococcus aureus (MRSA) and their linkage to the staphylococcal cassette chromosome mec (SCCmec) type.

Barada K, Hanaki H, Yamaguchi Y, Ikeda S, Akama H, Nakae T, Inamatsu T, Sunakawa K.

J Infect Chemother. 2007 Aug;13(4):213-8. Epub 2007 Aug 27.

PMID:
17721683
14.

[Antibody to IL-1 or IL-15].

Akama H.

Nihon Rinsho. 2007 Jul;65(7):1227-30. Review. Japanese.

PMID:
17642236
15.

Changes in central dopaminergic systems with the expression of Shh or GDNF in mice perinatally exposed to bisphenol-A.

Miyagawa K, Narita M, Narita M, Niikura K, Akama H, Tsurukawa Y, Suzuki T.

Nihon Shinkei Seishin Yakurigaku Zasshi. 2007 Apr;27(2):69-75.

PMID:
17515113
16.

Memory impairment associated with a dysfunction of the hippocampal cholinergic system induced by prenatal and neonatal exposures to bisphenol-A.

Miyagawa K, Narita M, Narita M, Akama H, Suzuki T.

Neurosci Lett. 2007 May 18;418(3):236-41. Epub 2007 Apr 11.

PMID:
17467901
17.

Trends in the gentamicin and arbekacin susceptibility of methicillin-resistant Staphylococcus aureus and the genes encoding aminoglycoside-modifying enzymes.

Barada K, Hanaki H, Ikeda S, Yamaguchi Y, Akama H, Nakae T, Inamatsu T, Sunakawa K.

J Infect Chemother. 2007 Apr;13(2):74-8. Epub 2007 May 8.

PMID:
17458673
18.

One third of Japanese patients with rheumatoid arthritis use complementary and alternative medicine.

Kajiyama H, Akama H, Yamanaka H, Shoji A, Matsuda Y, Tanaka E, Nakajima A, Terai C, Hara M, Tomatsu T, Saitoh T, Kamatani N.

Mod Rheumatol. 2006;16(6):355-9. Epub 2006 Dec 20.

PMID:
17164996
19.

Preliminary crystallographic analysis of the antibiotic discharge outer membrane lipoprotein OprM of Pseudomonas aeruginosa with an exceptionally long unit cell and complex lattice structure.

Akama H, Kanemaki M, Tsukihara T, Nakagawa A, Nakae T.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Jan 1;61(Pt 1):131-3. Epub 2004 Dec 24.

20.

Suppression of adjuvant-induced arthritic bone destruction by cyclooxygenase-2 selective agents with and without inhibitory potency against carbonic anhydrase II.

Katagiri M, Ogasawara T, Hoshi K, Chikazu D, Kimoto A, Noguchi M, Sasamata M, Harada S, Akama H, Tazaki H, Chung UI, Takato T, Nakamura K, Kawaguchi H.

J Bone Miner Res. 2006 Feb;21(2):219-27. Epub 2005 Nov 7.

21.

Multidrug transporter MexB of Pseudomonas aeruginosa: overexpression, purification, and initial structural characterization.

Mokhonov V, Mokhonova E, Yoshihara E, Masui R, Sakai M, Akama H, Nakae T.

Protein Expr Purif. 2005 Mar;40(1):91-100.

PMID:
15721776
22.

Forceful large-scale expression of "problematic" membrane proteins.

Mokhonova EI, Mokhonov VV, Akama H, Nakae T.

Biochem Biophys Res Commun. 2005 Feb 18;327(3):650-5.

PMID:
15649396
23.

Crystal structure of the drug discharge outer membrane protein, OprM, of Pseudomonas aeruginosa: dual modes of membrane anchoring and occluded cavity end.

Akama H, Kanemaki M, Yoshimura M, Tsukihara T, Kashiwagi T, Yoneyama H, Narita S, Nakagawa A, Nakae T.

J Biol Chem. 2004 Dec 17;279(51):52816-9. Epub 2004 Oct 26.

24.

Preparation of micrometer-sized poly(methyl methacrylate) particles with amphoteric initiator in aqueous media.

Gu S, Akama H, Nagao D, Kobayashi Y, Konno M.

Langmuir. 2004 Sep 14;20(19):7948-51.

PMID:
15350057
25.

Role of the membrane fusion protein in the assembly of resistance-nodulation-cell division multidrug efflux pump in Pseudomonas aeruginosa.

Mokhonov VV, Mokhonova EI, Akama H, Nakae T.

Biochem Biophys Res Commun. 2004 Sep 17;322(2):483-9.

PMID:
15325256
26.

Crystal structure of the membrane fusion protein, MexA, of the multidrug transporter in Pseudomonas aeruginosa.

Akama H, Matsuura T, Kashiwagi S, Yoneyama H, Narita S, Tsukihara T, Nakagawa A, Nakae T.

J Biol Chem. 2004 Jun 18;279(25):25939-42. Epub 2004 Apr 26.

27.

Proximal symphalangism associated with conductive hearing loss.

Akama H, Kiyotaki M, Motojima S.

Arthritis Care Res. 2000 Oct;13(5):333-4. No abstract available.

PMID:
14635304
28.

Mutations affecting DNA-binding activity of the MexR repressor of mexR-mexA-mexB-oprM operon expression.

Saito K, Akama H, Yoshihara E, Nakae T.

J Bacteriol. 2003 Oct;185(20):6195-8.

29.

A new syndrome: multiple dislocations of distal interphalangeal joints associated with interstitial pneumonia, Sjögren's syndrome, and positive autoantibodies.

Nanke Y, Kotake S, Akama H, Kamatani N.

Mod Rheumatol. 2003 Jun;13(2):103-6. doi: 10.3109/s10165-003-0207-z.

PMID:
24387167
30.

Testicular sperm extraction with intracytoplasmic sperm injection for male infertility.

Imamoto T, Suzuki H, Ichikawa T, Ito H, Kawana Y, Shiseki Y, Akama H, Naito M.

Reprod Med Biol. 2003 Mar 25;2(1):31-35. doi: 10.1046/j.1445-5781.2003.00017.x. eCollection 2003 Mar.

31.

[Pharmacogenetics of disease modifying anti-rheumatic drugs].

Taniguchi A, Urano W, Tanaka E, Akama H, Yamanaka H, Kamatani N.

Nihon Rinsho. 2002 Dec;60(12):2339-44. Japanese.

PMID:
12510359
32.

[Primary adrenal lymphoma: a case report and literature review in Japan].

Toubai T, Akama H, Takagawa M, Ishida S, Kasai M, Tanaka J, Imamura M.

Rinsho Ketsueki. 2002 Sep;43(9):851-6. Review. Japanese.

PMID:
12412291
33.
34.

[Pharmacogenomics of the immunosuppressive agents].

Taniguchi A, Urano W, Tanaka E, Kitamura Y, Saito M, Akama H, Yamanak H, Saito T, Kamatani N.

Nihon Rinsho Meneki Gakkai Kaishi. 2002 Feb;25(1):105-9. Review. Japanese. No abstract available.

PMID:
11963167
35.
36.

[Fever of unknown origin due to sclerosing mediastinitis].

Toubai T, Akama H, Ichikawa K, Uno K, Kitami M, Takagawa M, Chiba J, Arakawa M, Ishida S, Takahashi T, Sasaki Y.

Nihon Naika Gakkai Zasshi. 2001 Nov 10;90(11):2275-8. Japanese. No abstract available.

PMID:
11769525
37.

Unusual presentations of thoracic tumors: Case 2. Malignant mesothelioma mimicking rheumatoid pleurisy.

Nanke Y, Akama H, Hebisawa A, Suzuki M, Akagawa S, Tateishi M, Yamagata H, Kawai T, Kamatani N.

J Clin Oncol. 2001 Sep 1;19(17):3782-4. No abstract available.

PMID:
11533103
38.

[Purpura due to vasculitis induced by interferon therapy for a patient with chronic hepatitis type C].

Toubai T, Akama H, Tabata N, Uno K, Kitami M, Takagawa M, Fukuda M, Chiba J, Arakawa M, Ishida S, Sasaki Y.

Nihon Naika Gakkai Zasshi. 2001 Jul 10;90(7):1330-2. Japanese. No abstract available.

PMID:
11519113
39.

Antiphospholipid syndrome with complete abdominal aorta occlusion and chondritis.

Saji M, Nakajima A, Sendo W, Tanaka M, Koseki Y, Ichikawa N, Harigai M, Akama H, Taniguchi A, Terai C, Hara M, Kamatani N.

Mod Rheumatol. 2001 Jun;11(2):159-61. doi: 10.3109/s101650170030.

PMID:
24383695
40.

Glucosamine and chondroitin for osteoarthritis.

Akama H, Saito S.

Arthritis Rheum. 2001 Feb;45(1):107. No abstract available.

41.
42.

Obturator herniation visualized by multislice helical CT.

Takase K, Furuta A, Akama H.

J Am Coll Surg. 2001 Mar;192(3):411. No abstract available.

PMID:
11245385
43.

Rapidly progressive glomerulonephritis with D-penicillamine.

Nanke Y, Akama H, Terai C, Kamatani N.

Am J Med Sci. 2000 Dec;320(6):398-402.

PMID:
11149553
44.

Progressive appearance of overlap syndrome together with autoantibodies in a patient with fatal thrombotic microangiopathy.

Nanke Y, Akama H, Yamanaka H, Hara M, Kamatani N.

Am J Med Sci. 2000 Nov;320(5):348-51.

PMID:
11093690
45.

Multiple distal interphalangeal joint dislocation.

Nanke Y, Kotake S, Akama H, Yamagata H, Kamatani N.

Lancet. 2000 Nov 4;356(9241):1550. No abstract available.

PMID:
11075767
46.

Multiple dislocations of distal interphalangeal joints associated with interstitial pneumonia and Sjögren's syndrome: a possible new complex.

Nanke Y, Kotake S, Akama H, Usuda S, Tateishi M, Yamagata H, Kamatani N.

J Rheumatol. 2000 Jul;27(7):1798-800. No abstract available.

PMID:
10914873
47.

Raised plasma adrenomedullin patients with systemic sclerosis complicated by pulmonary hypertension.

Nanke Y, Kotake S, Akama H, Shimamoto K, Hara M, Kamatani N.

Ann Rheum Dis. 2000 Jun;59(6):493-4. No abstract available.

48.

Management of fibromyalgia.

Akama H.

Ann Intern Med. 2000 Jun 20;132(12):1005. No abstract available.

PMID:
10858157
49.

Changes in clinical features and long-term prognosis in patients with pheochromocytoma.

Noshiro T, Shimizu K, Watanabe T, Akama H, Shibukawa S, Miura W, Ito S, Miura Y.

Am J Hypertens. 2000 Jan;13(1 Pt 1):35-43.

PMID:
10678269
50.

[MPO-ANCA positive rapidly progressive glomerulonephritis in a patient with rheumatoid arthritis during treatment with D-penicillamine].

Nanke Y, Akama H, Terai C, Hara M, Kamatani N.

Nihon Rinsho Meneki Gakkai Kaishi. 1999 Oct;22(5):354-9. Japanese.

PMID:
10616290

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