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Items: 1 to 50 of 362

1.

Multiplex Neural Circuit Tracing With G-Deleted Rabies Viral Vectors.

Suzuki T, Morimoto N, Akaike A, Osakada F.

Front Neural Circuits. 2020 Jan 10;13:77. doi: 10.3389/fncir.2019.00077. eCollection 2019.

2.

Protective Effect of 2',3'-Dihydroxy-4',6'-dimethoxychalcone on Glutamate-Induced Neurotoxicity in Primary Cortical Cultures.

Taguchi K, Izumi Y, Takada-Takatori Y, Akaike A, Kume T.

Biol Pharm Bull. 2020;43(1):184-187. doi: 10.1248/bpb.b19-00718.

3.

Increased CCL6 expression in astrocytes and neuronal protection from neuron-astrocyte interactions.

Nakagawa S, Izumi Y, Takada-Takatori Y, Akaike A, Kume T.

Biochem Biophys Res Commun. 2019 Nov 19;519(4):777-782. doi: 10.1016/j.bbrc.2019.09.030. Epub 2019 Sep 21.

PMID:
31551151
4.

Effects of 2'-3'-dihydroxy-4',6'-dimethoxychalcone derived from green perilla on auricle thickness in chronic contact dermatitis model mice.

Takada-Takatori Y, Takeda Y, Imai R, Izumi Y, Akaike A, Tsuchida K, Kume T.

J Pharmacol Sci. 2019 Sep;141(1):17-24. doi: 10.1016/j.jphs.2019.08.004. Epub 2019 Aug 28.

5.

Protective Effects of 2',3'-Dihydroxy-4',6'-dimethoxychalcone Derived from Green Perilla Leaves against UV Radiation-Induced Cell Injury in Human Cultured Keratinocytes.

Takada-Takatori Y, Tomii Y, Takemasa S, Takeda Y, Izumi Y, Akaike A, Tsuchida K, Kume T.

Biol Pharm Bull. 2019 Nov 1;42(11):1936-1941. doi: 10.1248/bpb.b19-00618. Epub 2019 Aug 27.

6.

Protective Effect of Green Perilla-Derived Chalcone Derivative DDC on Amyloid β Protein-Induced Neurotoxicity in Primary Cortical Neurons.

Iwasaki M, Izuo N, Izumi Y, Takada-Takatori Y, Akaike A, Kume T.

Biol Pharm Bull. 2019 Nov 1;42(11):1942-1946. doi: 10.1248/bpb.b19-00657. Epub 2019 Aug 29.

7.

Donepezil modulates amyloid precursor protein endocytosis and reduction by up-regulation of SNX33 expression in primary cortical neurons.

Takada-Takatori Y, Nakagawa S, Kimata R, Nao Y, Mizukawa Y, Urushidani T, Izumi Y, Akaike A, Tsuchida K, Kume T.

Sci Rep. 2019 Aug 15;9(1):11922. doi: 10.1038/s41598-019-47462-4.

8.

Overview.

Akaike A, Izumi Y.

In: Akaike A, Shimohama S, Misu Y, editors. Nicotinic Acetylcholine Receptor Signaling in Neuroprotection [Internet]. Singapore: Springer; 2018. Chapter 1.
2018 Apr 4.

9.

Inhibitory effect of the gut microbial linoleic acid metabolites, 10-oxo-trans-11-octadecenoic acid and 10-hydroxy-cis-12-octadecenoic acid, on BV-2 microglial cell activation.

Ikeguchi S, Izumi Y, Kitamura N, Kishino S, Ogawa J, Akaike A, Kume T.

J Pharmacol Sci. 2018 Sep;138(1):9-15. doi: 10.1016/j.jphs.2018.06.015. Epub 2018 Sep 5.

10.

[Contribution to the Development of Pharmaceutical Education in Six-year and Four-year Programs].

Akaike A.

Yakugaku Zasshi. 2018;138(9):1127-1133. doi: 10.1248/yakushi.18-00097. Review. Japanese.

11.

Neuroprotective effect of an Nrf2-ARE activator identified from a chemical library on dopaminergic neurons.

Izumi Y, Kataoka H, Inose Y, Akaike A, Koyama Y, Kume T.

Eur J Pharmacol. 2018 Jan 5;818:470-479. doi: 10.1016/j.ejphar.2017.11.023. Epub 2017 Nov 14.

PMID:
29154837
12.

Efficacy of a Prevention Program for Medial Elbow Injuries in Youth Baseball Players.

Sakata J, Nakamura E, Suzuki T, Suzukawa M, Akaike A, Shimizu K, Hirose N.

Am J Sports Med. 2018 Feb;46(2):460-469. doi: 10.1177/0363546517738003. Epub 2017 Nov 2.

PMID:
29095655
13.

PE859, A Novel Curcumin Derivative, Inhibits Amyloid-β and Tau Aggregation, and Ameliorates Cognitive Dysfunction in Senescence-Accelerated Mouse Prone 8.

Okuda M, Fujita Y, Hijikuro I, Wada M, Uemura T, Kobayashi Y, Waku T, Tanaka N, Nishimoto T, Izumi Y, Kume T, Akaike A, Takahashi T, Sugimoto H.

J Alzheimers Dis. 2017;59(1):313-328. doi: 10.3233/JAD-161017.

PMID:
28598836
14.

Inhibitory effect of donepezil on bradykinin-induced increase in the intracellular calcium concentration in cultured cortical astrocytes.

Makitani K, Nakagawa S, Izumi Y, Akaike A, Kume T.

J Pharmacol Sci. 2017 May;134(1):37-44. doi: 10.1016/j.jphs.2017.03.008. Epub 2017 Apr 24.

15.

Integrin α5β1 expression on dopaminergic neurons is involved in dopaminergic neurite outgrowth on striatal neurons.

Izumi Y, Wakita S, Kanbara C, Nakai T, Akaike A, Kume T.

Sci Rep. 2017 Feb 8;7:42111. doi: 10.1038/srep42111.

16.

Protective effect of Nrf2-ARE activator isolated from green perilla leaves on dopaminergic neuronal loss in a Parkinson's disease model.

Masaki Y, Izumi Y, Matsumura A, Akaike A, Kume T.

Eur J Pharmacol. 2017 Mar 5;798:26-34. doi: 10.1016/j.ejphar.2017.02.005. Epub 2017 Feb 4.

PMID:
28167258
17.

Physical Risk Factors for a Medial Elbow Injury in Junior Baseball Players: A Prospective Cohort Study of 353 Players.

Sakata J, Nakamura E, Suzukawa M, Akaike A, Shimizu K.

Am J Sports Med. 2017 Jan;45(1):135-143. doi: 10.1177/0363546516663931. Epub 2016 Oct 1.

PMID:
27604190
18.

Effect of vitamin K2 on the anticoagulant activity of warfarin during the perioperative period of catheter ablation: Population analysis of retrospective clinical data.

Zhou Z, Yano I, Odaka S, Morita Y, Shizuta S, Hayano M, Kimura T, Akaike A, Inui K, Matsubara K.

J Pharm Health Care Sci. 2016 Aug 4;2:17. doi: 10.1186/s40780-016-0053-8. eCollection 2016.

19.

Reduction of Immunoreactivity Against the C-Terminal Region of the Intracellular α-Synuclein by Exogenous α-Synuclein Aggregates: Possibility of Conformational Changes.

Izumi Y, Kondo N, Takahashi R, Akaike A, Kume T.

J Parkinsons Dis. 2016 Jun 16;6(3):569-79. doi: 10.3233/JPD-160835.

PMID:
27314756
20.

Protective Effect of Dimethyl Fumarate on an Oxidative Stress Model Induced by Sodium Nitroprusside in Mice.

Kume T, Suenaga A, Izumi Y, Akaike A.

Biol Pharm Bull. 2016;39(6):1055-9. doi: 10.1248/bpb.b16-00134.

21.

Compensatory role of the Nrf2-ARE pathway against paraquat toxicity: Relevance of 26S proteasome activity.

Izumi Y, Yamamoto N, Matsushima S, Yamamoto T, Takada-Takatori Y, Akaike A, Kume T.

J Pharmacol Sci. 2015 Nov;129(3):150-9. doi: 10.1016/j.jphs.2015.09.003. Epub 2015 Oct 9.

22.

In Vivo Talocrural Joint Contact Mechanics With Functional Ankle Instability.

Kobayashi T, Suzuki E, Yamazaki N, Suzukawa M, Akaike A, Shimizu K, Gamada K.

Foot Ankle Spec. 2015 Dec;8(6):445-53. doi: 10.1177/1938640015585967. Epub 2015 May 8.

PMID:
25956876
23.

Integrin-associated protein promotes neuronal differentiation of neural stem/progenitor cells.

Fujimura K, Niidome T, Shinozuka Y, Izumi Y, Kihara T, Sugimoto H, Akaike A, Kume T.

PLoS One. 2015 Feb 23;10(2):e0116741. doi: 10.1371/journal.pone.0116741. eCollection 2015.

24.

Serofendic acid protects against myocardial ischemia-reperfusion injury in rats.

Ioroi T, Akao M, Iguchi M, Kato M, Kimura T, Izumi Y, Akaike A, Kume T.

J Pharmacol Sci. 2014;126(3):274-80. Epub 2014 Nov 1.

25.

Fibular malalignment in individuals with chronic ankle instability.

Kobayashi T, Suzuki E, Yamazaki N, Suzukawa M, Akaike A, Shimizu K, Gamada K.

J Orthop Sports Phys Ther. 2014 Nov;44(11):872-8. doi: 10.2519/jospt.2014.5217. Epub 2014 Oct 9.

PMID:
25299632
26.

The effects of a semi-rigid brace or taping on talocrural and subtalar kinematics in chronic ankle instability.

Kobayashi T, Saka M, Suzuki E, Yamazaki N, Suzukawa M, Akaike A, Shimizu K, Gamada K.

Foot Ankle Spec. 2014 Dec;7(6):471-7. doi: 10.1177/1938640014543357. Epub 2014 Jul 21.

PMID:
25053794
27.
28.
29.

Endogenous dopamine is involved in the herbicide paraquat-induced dopaminergic cell death.

Izumi Y, Ezumi M, Takada-Takatori Y, Akaike A, Kume T.

Toxicol Sci. 2014 Jun;139(2):466-78. doi: 10.1093/toxsci/kfu054. Epub 2014 Apr 17.

PMID:
24743698
30.

Potential protective effect of highly bioavailable curcumin on an oxidative stress model induced by microinjection of sodium nitroprusside in mice brain.

Nazari QA, Takada-Takatori Y, Hashimoto T, Imaizumi A, Izumi Y, Akaike A, Kume T.

Food Funct. 2014 May;5(5):984-9. doi: 10.1039/c4fo00009a.

PMID:
24637610
31.

In vivo kinematics of the talocrural and subtalar joints during weightbearing ankle rotation in chronic ankle instability.

Kobayashi T, Saka M, Suzuki E, Yamazaki N, Suzukawa M, Akaike A, Shimizu K, Gamada K.

Foot Ankle Spec. 2014 Feb;7(1):13-9. doi: 10.1177/1938640013514269. Epub 2013 Dec 10.

PMID:
24334366
32.

Staurosporine induces dopaminergic neurite outgrowth through AMP-activated protein kinase/mammalian target of rapamycin signaling pathway.

Wakita S, Izumi Y, Nakai T, Adachi K, Takada-Takatori Y, Kume T, Akaike A.

Neuropharmacology. 2014 Feb;77:39-48. doi: 10.1016/j.neuropharm.2013.09.012. Epub 2013 Sep 22.

PMID:
24067927
33.

Protective effect of serofendic acid, administered intravenously, on cerebral ischemia-reperfusion injury in rats.

Ioroi T, Taguchi K, Izumi Y, Takada-Takatori Y, Akaike A, Kume T.

Brain Res. 2013 Sep 26;1532:99-105. doi: 10.1016/j.brainres.2013.08.013. Epub 2013 Aug 13.

34.

Neuroprotective effects of curcumin and highly bioavailable curcumin on oxidative stress induced by sodium nitroprusside in rat striatal cell culture.

Nazari QA, Kume T, Izuo N, Takada-Takatori Y, Imaizumi A, Hashimoto T, Izumi Y, Akaike A.

Biol Pharm Bull. 2013;36(8):1356-62.

35.

Non-toxic conformer of amyloid β may suppress amyloid β-induced toxicity in rat primary neurons: implications for a novel therapeutic strategy for Alzheimer's disease.

Izuo N, Murakami K, Sato M, Iwasaki M, Izumi Y, Shimizu T, Akaike A, Irie K, Kume T.

Biochem Biophys Res Commun. 2013 Aug 16;438(1):1-5. doi: 10.1016/j.bbrc.2013.05.106. Epub 2013 Jun 4.

PMID:
23747423
36.

Protective effect of luteolin on an oxidative-stress model induced by microinjection of sodium nitroprusside in mice.

Nazari QA, Kume T, Takada-Takatori Y, Izumi Y, Akaike A.

J Pharmacol Sci. 2013;122(2):109-17. Epub 2013 May 24.

37.

Toxicity in rat primary neurons through the cellular oxidative stress induced by the turn formation at positions 22 and 23 of Aβ42.

Izuo N, Kume T, Sato M, Murakami K, Irie K, Izumi Y, Akaike A.

ACS Chem Neurosci. 2012 Sep 19;3(9):674-81. Epub 2012 Jun 6.

38.

In vivo brain oxidative stress model induced by microinjection of sodium nitroprusside in mice.

Nazari QA, Mizuno K, Kume T, Takada-Takatori Y, Izumi Y, Akaike A.

J Pharmacol Sci. 2012;120(2):105-11. Epub 2012 Sep 26.

39.

Sox21 promotes hippocampal adult neurogenesis via the transcriptional repression of the Hes5 gene.

Matsuda S, Kuwako K, Okano HJ, Tsutsumi S, Aburatani H, Saga Y, Matsuzaki Y, Akaike A, Sugimoto H, Okano H.

J Neurosci. 2012 Sep 5;32(36):12543-57.

40.

Glycogen synthase kinase-3β activation mediates rotenone-induced cytotoxicity with the involvement of microtubule destabilization.

Hongo H, Kihara T, Kume T, Izumi Y, Niidome T, Sugimoto H, Akaike A.

Biochem Biophys Res Commun. 2012 Sep 14;426(1):94-9. doi: 10.1016/j.bbrc.2012.08.042. Epub 2012 Aug 17.

PMID:
22922102
41.

Isolation, identification, and biological evaluation of Nrf2-ARE activator from the leaves of green perilla (Perilla frutescens var. crispa f. viridis).

Izumi Y, Matsumura A, Wakita S, Akagi K, Fukuda H, Kume T, Irie K, Takada-Takatori Y, Sugimoto H, Hashimoto T, Akaike A.

Free Radic Biol Med. 2012 Aug 15;53(4):669-79. doi: 10.1016/j.freeradbiomed.2012.06.021. Epub 2012 Jun 27.

PMID:
22749808
42.

Glucocorticoids decrease astrocyte numbers by reducing glucocorticoid receptor expression in vitro and in vivo.

Unemura K, Kume T, Kondo M, Maeda Y, Izumi Y, Akaike A.

J Pharmacol Sci. 2012;119(1):30-9. Epub 2012 Apr 28.

44.

Involvement of ERK in NMDA receptor-independent cortical neurotoxicity of hydrogen sulfide.

Kurokawa Y, Sekiguchi F, Kubo S, Yamasaki Y, Matsuda S, Okamoto Y, Sekimoto T, Fukatsu A, Nishikawa H, Kume T, Fukushima N, Akaike A, Kawabata A.

Biochem Biophys Res Commun. 2011 Nov 4;414(4):727-32. doi: 10.1016/j.bbrc.2011.09.144. Epub 2011 Oct 6.

PMID:
22001931
45.

Functional and molecular interactions between Rac1 and FE65.

Wang PL, Niidome T, Kume T, Akaike A, Kihara T, Sugimoto H.

Neuroreport. 2011 Oct 5;22(14):716-20. doi: 10.1097/WNR.0b013e32834aca9d.

PMID:
21878794
46.

HMGB1 inhibitor glycyrrhizin attenuates intracerebral hemorrhage-induced injury in rats.

Ohnishi M, Katsuki H, Fukutomi C, Takahashi M, Motomura M, Fukunaga M, Matsuoka Y, Isohama Y, Izumi Y, Kume T, Inoue A, Akaike A.

Neuropharmacology. 2011 Oct-Nov;61(5-6):975-80. doi: 10.1016/j.neuropharm.2011.06.026. Epub 2011 Jul 6.

PMID:
21752338
47.

Dynamic component of sports is an important determinant factor of heart rate recovery.

Nagashima J, Matsumoto N, Takagi A, Musha H, Chikaraishi K, Sagehashi M, Nakagawa R, Ishige N, Fujimaki R, Akaike A, Seo R, Aoki H, Murayama M.

J Cardiol. 2011 Sep;58(2):191-6. doi: 10.1016/j.jjcc.2011.04.006. Epub 2011 Jun 21.

48.

Assessment of pharmacy students' communication competence using the Roter Interaction Analysis System during objective structured clinical examinations.

Kubota Y, Yano Y, Seki S, Takada K, Sakuma M, Morimoto T, Akaike A, Hiraide A.

Am J Pharm Educ. 2011 Apr 11;75(3):43.

49.

Na+/Ca2+ exchanger inhibitors inhibit neurite outgrowth in PC12 cells.

Oda T, Kume T, Izumi Y, Ishihara K, Sugmimoto H, Akaike A.

J Pharmacol Sci. 2011;116(1):128-31. Epub 2011 Apr 27.

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