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Items: 39


Protein kinase B controls Mycobacterium tuberculosis growth via phosphorylation of the transcriptional regulator Lsr2 at threonine 112.

Alqaseer K, Turapov O, Barthe P, Jagatia H, De Visch A, Roumestand C, Wegrzyn M, Bartek IL, Voskuil MI, O'Hare HM, Ajuh P, Bottrill AR, Witney AA, Cohen-Gonsaud M, Waddell SJ, Mukamolova GV.

Mol Microbiol. 2019 Dec;112(6):1847-1862. doi: 10.1111/mmi.14398. Epub 2019 Oct 10.


Mycobacterial phosphatase PstP regulates global serine threonine phosphorylation and cell division.

Iswahyudi, Mukamolova GV, Straatman-Iwanowska AA, Allcock N, Ajuh P, Turapov O, O'Hare HM.

Sci Rep. 2019 Jun 6;9(1):8337. doi: 10.1038/s41598-019-44841-9.


Two Faces of CwlM, an Essential PknB Substrate, in Mycobacterium tuberculosis.

Turapov O, Forti F, Kadhim B, Ghisotti D, Sassine J, Straatman-Iwanowska A, Bottrill AR, Moynihan PJ, Wallis R, Barthe P, Cohen-Gonsaud M, Ajuh P, Vollmer W, Mukamolova GV.

Cell Rep. 2018 Oct 2;25(1):57-67.e5. doi: 10.1016/j.celrep.2018.09.004.


End stage renal disease-induced hypercalcemia may promote aortic valve calcification via Annexin VI enrichment of valve interstitial cell derived-matrix vesicles.

Cui L, Rashdan NA, Zhu D, Milne EM, Ajuh P, Milne G, Helfrich MH, Lim K, Prasad S, Lerman DA, Vesey AT, Dweck MR, Jenkins WS, Newby DE, Farquharson C, Macrae VE.

J Cell Physiol. 2017 Nov;232(11):2985-2995. doi: 10.1002/jcp.25935. Epub 2017 May 24.


Characterization of the Tyrosine Kinase-Regulated Proteome in Breast Cancer by Combined use of RNA interference (RNAi) and Stable Isotope Labeling with Amino Acids in Cell Culture (SILAC) Quantitative Proteomics.

Stebbing J, Zhang H, Xu Y, Grothey A, Ajuh P, Angelopoulos N, Giamas G.

Mol Cell Proteomics. 2015 Sep;14(9):2479-92. doi: 10.1074/mcp.M115.048090. Epub 2015 Jun 18.


Piezo1 integration of vascular architecture with physiological force.

Li J, Hou B, Tumova S, Muraki K, Bruns A, Ludlow MJ, Sedo A, Hyman AJ, McKeown L, Young RS, Yuldasheva NY, Majeed Y, Wilson LA, Rode B, Bailey MA, Kim HR, Fu Z, Carter DA, Bilton J, Imrie H, Ajuh P, Dear TN, Cubbon RM, Kearney MT, Prasad RK, Evans PC, Ainscough JF, Beech DJ.

Nature. 2014 Nov 13;515(7526):279-282. doi: 10.1038/nature13701. Epub 2014 Aug 10.


Novel blood collection method allows plasma proteome analysis from single zebrafish.

Babaei F, Ramalingam R, Tavendale A, Liang Y, Yan LS, Ajuh P, Cheng SH, Lam YW.

J Proteome Res. 2013 Apr 5;12(4):1580-90. doi: 10.1021/pr3009226. Epub 2013 Feb 26.


Inhibition of pre-mRNA splicing by a synthetic Blom7α-interacting small RNA.

Löscher M, Schosserer M, Dausse E, Lee K, Ajuh P, Grillari-Voglauer R, Lamond AI, Toulmé JJ, Grillari J.

PLoS One. 2012;7(10):e47497. doi: 10.1371/journal.pone.0047497. Epub 2012 Oct 29.


Characterization of carbon nanotube protein corona by using quantitative proteomics.

Cai X, Ramalingam R, Wong HS, Cheng J, Ajuh P, Cheng SH, Lam YW.

Nanomedicine. 2013 Jul;9(5):583-93. doi: 10.1016/j.nano.2012.09.004. Epub 2012 Oct 29.


A quantitative proteomic analysis of lung epithelial (A549) cells infected with 2009 pandemic influenza A virus using stable isotope labelling with amino acids in cell culture.

Dove BK, Surtees R, Bean TJ, Munday D, Wise HM, Digard P, Carroll MW, Ajuh P, Barr JN, Hiscox JA.

Proteomics. 2012 May;12(9):1431-6. doi: 10.1002/pmic.201100470. Epub 2012 May 14.


Exo70, a subunit of the exocyst complex, interacts with SNEV(hPrp19/hPso4) and is involved in pre-mRNA splicing.

Dellago H, Löscher M, Ajuh P, Ryder U, Kaisermayer C, Grillari-Voglauer R, Fortschegger K, Gross S, Gstraunthaler A, Borth N, Eisenhaber F, Lamond AI, Grillari J.

Biochem J. 2011 Aug 15;438(1):81-91. doi: 10.1042/BJ20110183.


Quantitative phosphoproteomic analysis of prion-infected neuronal cells.

Wagner W, Ajuh P, Löwer J, Wessler S.

Cell Commun Signal. 2010 Sep 28;8:28. doi: 10.1186/1478-811X-8-28.


Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

Llères D, Denegri M, Biggiogera M, Ajuh P, Lamond AI.

EMBO Rep. 2010 Jun;11(6):445-51. doi: 10.1038/embor.2010.64. Epub 2010 May 14.


Quantitative proteomics using stable isotope labeling with amino acids in cell culture reveals changes in the cytoplasmic, nuclear, and nucleolar proteomes in Vero cells infected with the coronavirus infectious bronchitis virus.

Emmott E, Rodgers MA, Macdonald A, McCrory S, Ajuh P, Hiscox JA.

Mol Cell Proteomics. 2010 Sep;9(9):1920-36. doi: 10.1074/mcp.M900345-MCP200. Epub 2010 May 13.


Blom7alpha is a novel heterogeneous nuclear ribonucleoprotein K homology domain protein involved in pre-mRNA splicing that interacts with SNEVPrp19-Pso4.

Grillari J, Löscher M, Denegri M, Lee K, Fortschegger K, Eisenhaber F, Ajuh P, Lamond AI, Katinger H, Grillari-Voglauer R.

J Biol Chem. 2009 Oct 16;284(42):29193-204. doi: 10.1074/jbc.M109.036632. Epub 2009 Jul 29.


Regulation of cyclin D1 RNA stability by SNIP1.

Bracken CP, Wall SJ, Barré B, Panov KI, Ajuh PM, Perkins ND.

Cancer Res. 2008 Sep 15;68(18):7621-8. doi: 10.1158/0008-5472.CAN-08-1217.


SNEV is an evolutionarily conserved splicing factor whose oligomerization is necessary for spliceosome assembly.

Grillari J, Ajuh P, Stadler G, Löscher M, Voglauer R, Ernst W, Chusainow J, Eisenhaber F, Pokar M, Fortschegger K, Grey M, Lamond AI, Katinger H.

Nucleic Acids Res. 2005 Dec 6;33(21):6868-83. Print 2005.


FRET analyses of the U2AF complex localize the U2AF35/U2AF65 interaction in vivo and reveal a novel self-interaction of U2AF35.

Chusainow J, Ajuh PM, Trinkle-Mulcahy L, Sleeman JE, Ellenberg J, Lamond AI.

RNA. 2005 Aug;11(8):1201-14.


Interaction of U-box E3 ligase SNEV with PSMB4, the beta7 subunit of the 20 S proteasome.

Löscher M, Fortschegger K, Ritter G, Wostry M, Voglauer R, Schmid JA, Watters S, Rivett AJ, Ajuh P, Lamond AI, Katinger H, Grillari J.

Biochem J. 2005 Jun 1;388(Pt 2):593-603.


hLodestar/HuF2 interacts with CDC5L and is involved in pre-mRNA splicing.

Leonard D, Ajuh P, Lamond AI, Legerski RJ.

Biochem Biophys Res Commun. 2003 Sep 5;308(4):793-801.


snRNP protein expression enhances the formation of Cajal bodies containing p80-coilin and SMN.

Sleeman JE, Ajuh P, Lamond AI.

J Cell Sci. 2001 Dec;114(Pt 24):4407-19.


A direct interaction between the carboxyl-terminal region of CDC5L and the WD40 domain of PLRG1 is essential for pre-mRNA splicing.

Ajuh P, Sleeman J, Chusainow J, Lamond AI.

J Biol Chem. 2001 Nov 9;276(45):42370-81. Epub 2001 Sep 5.


SPF30 is an essential human splicing factor required for assembly of the U4/U5/U6 tri-small nuclear ribonucleoprotein into the spliceosome.

Rappsilber J, Ajuh P, Lamond AI, Mann M.

J Biol Chem. 2001 Aug 17;276(33):31142-50. Epub 2001 Apr 30.


PRCC, the commonest TFE3 fusion partner in papillary renal carcinoma is associated with pre-mRNA splicing factors.

Skalsky YM, Ajuh PM, Parker C, Lamond AI, Goodwin G, Cooper CS.

Oncogene. 2001 Jan 11;20(2):178-87.


Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry.

Ajuh P, Kuster B, Panov K, Zomerdijk JC, Mann M, Lamond AI.

EMBO J. 2000 Dec 1;19(23):6569-81.


Functional coexpression of serine protein kinase SRPK1 and its substrate ASF/SF2 in Escherichia coli.

Yue BG, Ajuh P, Akusjärvi G, Lamond AI, Kreivi JP.

Nucleic Acids Res. 2000 Mar 1;28(5):E14.


Association of a protein phosphatase 1 activity with the human factor C1 (HCF) complex.

Ajuh PM, Browne GJ, Hawkes NA, Cohen PT, Roberts SG, Lamond AI.

Nucleic Acids Res. 2000 Feb 1;28(3):678-86.


Nuclear organisation of NIPP1, a regulatory subunit of protein phosphatase 1 that associates with pre-mRNA splicing factors.

Trinkle-Mulcahy L, Ajuh P, Prescott A, Claverie-Martin F, Cohen S, Lamond AI, Cohen P.

J Cell Sci. 1999 Jan;112 ( Pt 2):157-68.


Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex.

Neubauer G, King A, Rappsilber J, Calvio C, Watson M, Ajuh P, Sleeman J, Lamond A, Mann M.

Nat Genet. 1998 Sep;20(1):46-50.


Loa loa: structural diversity of a 15-kDa repetitive antigen.

Ajuh PM, Akue JP, Boutin P, Everaere S, Egwang TG.

Exp Parasitol. 1995 Sep;81(2):145-53.


Classical and novel approaches to the detection and localization of the numerous modified nucleotides in eukaryotic ribosomal RNA.

Maden BE, Corbett ME, Heeney PA, Pugh K, Ajuh PM.

Biochimie. 1995;77(1-2):22-9. Review.


Structure probing of a highly methylated region in Xenopus laevis 28S ribosomal RNA.

Ajuh PM, Maden EB.

Biochem Soc Trans. 1993 Nov;21(4):464S. No abstract available.


Cloning and characterization of a Loa loa-specific repetitive DNA.

Egwang TG, Ajuh PM, Akue JP.

Mol Biochem Parasitol. 1992 Dec;56(2):189-96.


28S ribosomal RNA in Xenopus borealis: gene sequence and differences from Xenopus laevis sequence.

Ajuh PM, Maden H.

Biochem Soc Trans. 1990 Aug;18(4):657-8. No abstract available.


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