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Items: 18

1.

Oncogenic splicing factor SRSF3 regulates ILF3 alternative splicing to promote cancer cell proliferation and transformation.

Jia R, Ajiro M, Yu L, McCoy P Jr, Zheng ZM.

RNA. 2019 May;25(5):630-644. doi: 10.1261/rna.068619.118. Epub 2019 Feb 22.

PMID:
30796096
2.

Rescue of recurrent deep intronic mutation underlying cell type-dependent quantitative NEMO deficiency.

Boisson B, Honda Y, Ajiro M, Bustamante J, Bendavid M, Gennery AR, Kawasaki Y, Ichishima J, Osawa M, Nihira H, Shiba T, Tanaka T, Chrabieh M, Bigio B, Hur H, Itan Y, Liang Y, Okada S, Izawa K, Nishikomori R, Ohara O, Heike T, Abel L, Puel A, Saito MK, Casanova JL, Hagiwara M, Yasumi T.

J Clin Invest. 2019 Feb 1;129(2):583-597. doi: 10.1172/JCI124011. Epub 2018 Dec 18.

3.

CDK9 Inhibitor FIT-039 Suppresses Viral Oncogenes E6 and E7 and Has a Therapeutic Effect on HPV-Induced Neoplasia.

Ajiro M, Sakai H, Onogi H, Yamamoto M, Sumi E, Sawada T, Nomura T, Kabashima K, Hosoya T, Hagiwara M.

Clin Cancer Res. 2018 Sep 15;24(18):4518-4528. doi: 10.1158/1078-0432.CCR-17-3119. Epub 2018 Apr 30.

4.

Viral DNA Replication Orientation and hnRNPs Regulate Transcription of the Human Papillomavirus 18 Late Promoter.

Wang X, Liu H, Ge H, Ajiro M, Sharma NR, Meyers C, Morozov P, Tuschl T, Klar A, Court D, Zheng ZM.

MBio. 2017 May 30;8(3). pii: e00713-17. doi: 10.1128/mBio.00713-17.

5.

Retinoid derivative Tp80 exhibits anti-hepatitis C virus activity through restoration of GI-GPx expression.

Nguyen BN, Okuno Y, Ajiro M, Iida K, Denawa M, Yamamoto M, Sakamoto N, Kagechika H, Hagiwara M.

J Med Virol. 2017 Jul;89(7):1224-1234. doi: 10.1002/jmv.24739. Epub 2017 Mar 28.

PMID:
27922182
7.

A genome landscape of SRSF3-regulated splicing events and gene expression in human osteosarcoma U2OS cells.

Ajiro M, Jia R, Yang Y, Zhu J, Zheng ZM.

Nucleic Acids Res. 2016 Feb 29;44(4):1854-70. doi: 10.1093/nar/gkv1500. Epub 2015 Dec 23.

8.

Cell Type- and Tissue Context-dependent Nuclear Distribution of Human Ago2.

Sharma NR, Wang X, Majerciak V, Ajiro M, Kruhlak M, Meyers C, Zheng ZM.

J Biol Chem. 2016 Jan 29;291(5):2302-9. doi: 10.1074/jbc.C115.695049. Epub 2015 Dec 23.

9.

Vemurafenib-resistant BRAF selects alternative branch points different from its wild-type BRAF in intron 8 for RNA splicing.

Ajiro M, Zheng ZM.

Cell Biosci. 2015 Dec 21;5:70. doi: 10.1186/s13578-015-0061-7. eCollection 2015.

10.

Adapted Resistance to the Knockdown Effect of shRNA-Derived Srsf3 siRNAs in Mouse Littermates.

Ajiro M, Jia R, Wang RH, Deng CX, Zheng ZM.

Int J Biol Sci. 2015 Sep 3;11(11):1248-56. doi: 10.7150/ijbs.13011. eCollection 2015.

11.

Oncogenes and RNA splicing of human tumor viruses.

Ajiro M, Zheng ZM.

Emerg Microbes Infect. 2014 Sep;3(9):e63. doi: 10.1038/emi.2014.62. Epub 2014 Sep 3. Review.

12.
13.

Both decreased and increased SRPK1 levels promote cancer by interfering with PHLPP-mediated dephosphorylation of Akt.

Wang P, Zhou Z, Hu A, Ponte de Albuquerque C, Zhou Y, Hong L, Sierecki E, Ajiro M, Kruhlak M, Harris C, Guan KL, Zheng ZM, Newton AC, Sun P, Zhou H, Fu XD.

Mol Cell. 2014 May 8;54(3):378-91. doi: 10.1016/j.molcel.2014.03.007. Epub 2014 Apr 3.

14.

Intron definition and a branch site adenosine at nt 385 control RNA splicing of HPV16 E6*I and E7 expression.

Ajiro M, Jia R, Zhang L, Liu X, Zheng ZM.

PLoS One. 2012;7(10):e46412. doi: 10.1371/journal.pone.0046412. Epub 2012 Oct 4.

15.

Downregulation of splicing factor SRSF3 induces p53β, an alternatively spliced isoform of p53 that promotes cellular senescence.

Tang Y, Horikawa I, Ajiro M, Robles AI, Fujita K, Mondal AM, Stauffer JK, Zheng ZM, Harris CC.

Oncogene. 2013 May 30;32(22):2792-8. doi: 10.1038/onc.2012.288. Epub 2012 Jul 9.

16.

Critical involvement of RQCD1 in the EGFR-Akt pathway in mammary carcinogenesis.

Ajiro M, Nishidate T, Katagiri T, Nakamura Y.

Int J Oncol. 2010 Nov;37(5):1085-93.

PMID:
20878056
17.

Involvement of RQCD1 overexpression, a novel cancer-testis antigen, in the Akt pathway in breast cancer cells.

Ajiro M, Katagiri T, Ueda K, Nakagawa H, Fukukawa C, Lin ML, Park JH, Nishidate T, Daigo Y, Nakamura Y.

Int J Oncol. 2009 Oct;35(4):673-81.

PMID:
19724902
18.

Involvement of G-patch domain containing 2 overexpression in breast carcinogenesis.

Lin ML, Fukukawa C, Park JH, Naito K, Kijima K, Shimo A, Ajiro M, Nishidate T, Nakamura Y, Katagiri T.

Cancer Sci. 2009 Aug;100(8):1443-50. doi: 10.1111/j.1349-7006.2009.01185.x. Epub 2009 May 4.

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