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Items: 26

1.

IL-34-Dependent Intrarenal and Systemic Mechanisms Promote Lupus Nephritis in MRL-Faslpr Mice.

Wada Y, Gonzalez-Sanchez HM, Weinmann-Menke J, Iwata Y, Ajay AK, Meineck M, Kelley VR.

J Am Soc Nephrol. 2019 Jan 8. pii: ASN.2018090901. doi: 10.1681/ASN.2018090901. [Epub ahead of print]

PMID:
30622154
2.

The molecular connection of histopathological heterogeneity in hepatocellular carcinoma: A role of Wnt and Hedgehog signaling pathways.

Tripathy A, Thakurela S, Sahu MK, Uthanasingh K, Behera M, Ajay AK, Kumari R.

PLoS One. 2018 Dec 4;13(12):e0208194. doi: 10.1371/journal.pone.0208194. eCollection 2018.

3.

Silencing SMOC2 ameliorates kidney fibrosis by inhibiting fibroblast to myofibroblast transformation.

Gerarduzzi C, Kumar RK, Trivedi P, Ajay AK, Iyer A, Boswell S, Hutchinson JN, Waikar SS, Vaidya VS.

JCI Insight. 2017 Apr 20;2(8). pii: 90299. doi: 10.1172/jci.insight.90299. [Epub ahead of print]

4.

Constitutively activated ERK sensitizes cancer cells to doxorubicin: Involvement of p53-EGFR-ERK pathway.

Kumari R, Chouhan S, Singh S, Chhipa RR, Ajay AK, Bhat MK.

J Biosci. 2017 Mar;42(1):31-41.

5.

RNA-binding Protein Musashi Homologue 1 Regulates Kidney Fibrosis by Translational Inhibition of p21 and Numb mRNA.

Jadhav S, Ajay AK, Trivedi P, Seematti J, Pellegrini K, Craciun F, Vaidya VS.

J Biol Chem. 2016 Jul 1;291(27):14085-94. doi: 10.1074/jbc.M115.713289. Epub 2016 Apr 28.

6.

Fat on sale: role of adipose-derived stem cells as anti-fibrosis agent in regenerative medicine.

Gupta MK, Ajay AK.

Stem Cell Res Ther. 2015 Dec 1;6:233. doi: 10.1186/s13287-015-0246-3.

7.

Proteasomal inhibition sensitizes cervical cancer cells to mitomycin C-induced bystander effect: the role of tumor microenvironment.

Singh SV, Ajay AK, Mohammad N, Malvi P, Chaube B, Meena AS, Bhat MK.

Cell Death Dis. 2015 Oct 22;6:e1934. doi: 10.1038/cddis.2015.292.

8.

RNA Sequencing Identifies Novel Translational Biomarkers of Kidney Fibrosis.

Craciun FL, Bijol V, Ajay AK, Rao P, Kumar RK, Hutchinson J, Hofmann O, Joshi N, Luyendyk JP, Kusebauch U, Moss CL, Srivastava A, Himmelfarb J, Waikar SS, Moritz RL, Vaidya VS.

J Am Soc Nephrol. 2016 Jun;27(6):1702-13. doi: 10.1681/ASN.2015020225. Epub 2015 Oct 8.

9.

A Quantitative Approach to Screen for Nephrotoxic Compounds In Vitro.

Adler M, Ramm S, Hafner M, Muhlich JL, Gottwald EM, Weber E, Jaklic A, Ajay AK, Svoboda D, Auerbach S, Kelly EJ, Himmelfarb J, Vaidya VS.

J Am Soc Nephrol. 2016 Apr;27(4):1015-28. doi: 10.1681/ASN.2015010060. Epub 2015 Aug 10.

10.

IL-34 mediates acute kidney injury and worsens subsequent chronic kidney disease.

Baek JH, Zeng R, Weinmann-Menke J, Valerius MT, Wada Y, Ajay AK, Colonna M, Kelley VR.

J Clin Invest. 2015 Aug 3;125(8):3198-214. doi: 10.1172/JCI81166. Epub 2015 Jun 29.

11.

MicroRNA-21 promotes Th17 differentiation and mediates experimental autoimmune encephalomyelitis.

Murugaiyan G, da Cunha AP, Ajay AK, Joller N, Garo LP, Kumaradevan S, Yosef N, Vaidya VS, Weiner HL.

J Clin Invest. 2015 Mar 2;125(3):1069-80. doi: 10.1172/JCI74347. Epub 2015 Feb 2.

12.

Pharmacological and genetic depletion of fibrinogen protects from kidney fibrosis.

Craciun FL, Ajay AK, Hoffmann D, Saikumar J, Fabian SL, Bijol V, Humphreys BD, Vaidya VS.

Am J Physiol Renal Physiol. 2014 Aug 15;307(4):F471-84. doi: 10.1152/ajprenal.00189.2014. Epub 2014 Jul 9.

13.

A bioinformatics approach identifies signal transducer and activator of transcription-3 and checkpoint kinase 1 as upstream regulators of kidney injury molecule-1 after kidney injury.

Ajay AK, Kim TM, Ramirez-Gonzalez V, Park PJ, Frank DA, Vaidya VS.

J Am Soc Nephrol. 2014 Jan;25(1):105-18. doi: 10.1681/ASN.2013020161. Epub 2013 Oct 24.

14.

Heterozygosity for fibrinogen results in efficient resolution of kidney ischemia reperfusion injury.

Ajay AK, Saikumar J, Bijol V, Vaidya VS.

PLoS One. 2012;7(9):e45628. doi: 10.1371/journal.pone.0045628. Epub 2012 Sep 19.

15.

Human papillomavirus 18 E6 inhibits phosphorylation of p53 expressed in HeLa cells.

Ajay AK, Meena AS, Bhat MK.

Cell Biosci. 2012 Jan 13;2:2. doi: 10.1186/2045-3701-2-2.

16.

Synthesis, characterization, plasmid cleavage and cytotoxicity of cancer cells by a copper(II) complex of anthracenyl-terpyridine.

Kumar A, Chinta JP, Ajay AK, Bhat MK, Rao CP.

Dalton Trans. 2011 Nov 7;40(41):10865-72. doi: 10.1039/c1dt10201j. Epub 2011 Jun 28.

PMID:
21709916
17.

Fibrinogen β-derived Bβ(15-42) peptide protects against kidney ischemia/reperfusion injury.

Krishnamoorthy A, Ajay AK, Hoffmann D, Kim TM, Ramirez V, Campanholle G, Bobadilla NA, Waikar SS, Vaidya VS.

Blood. 2011 Aug 18;118(7):1934-42. doi: 10.1182/blood-2011-02-338061. Epub 2011 Jun 17.

18.

Diet-induced obesity increases melanoma progression: involvement of Cav-1 and FASN.

Pandey V, Vijayakumar MV, Ajay AK, Malvi P, Bhat MK.

Int J Cancer. 2012 Feb 1;130(3):497-508. doi: 10.1002/ijc.26048. Epub 2011 Apr 27.

19.
20.

Cdk5 phosphorylates non-genotoxically overexpressed p53 following inhibition of PP2A to induce cell cycle arrest/apoptosis and inhibits tumor progression.

Ajay AK, Upadhyay AK, Singh S, Vijayakumar MV, Kumari R, Pandey V, Boppana R, Bhat MK.

Mol Cancer. 2010 Jul 31;9:204. doi: 10.1186/1476-4598-9-204.

21.

Mitomycin C induces bystander killing in homogeneous and heterogeneous hepatoma cellular models.

Kumari R, Sharma A, Ajay AK, Bhat MK.

Mol Cancer. 2009 Oct 21;8:87. doi: 10.1186/1476-4598-8-87.

22.

Cell cycle regulatory protein 5 (Cdk5) is a novel downstream target of ERK in carboplatin induced death of breast cancer cells.

Upadhyay AK, Ajay AK, Singh S, Bhat MK.

Curr Cancer Drug Targets. 2008 Dec;8(8):741-52.

PMID:
19075597
23.

Microtubular conductometric biosensor for ethanol detection.

Ajay AK, Srivastava DN.

Biosens Bioelectron. 2007 Sep 30;23(2):281-4. Epub 2007 May 5.

PMID:
17555954
24.

p53 regulates ERK activation in carboplatin induced apoptosis in cervical carcinoma: a novel target of p53 in apoptosis.

Singh S, Upadhyay AK, Ajay AK, Bhat MK.

FEBS Lett. 2007 Jan 23;581(2):289-95. Epub 2006 Dec 29.

25.

Gadd45alpha does not modulate the carboplatin or 5-fluorouracil-induced apoptosis in human papillomavirus-positive cells.

Singh S, Upadhyay AK, Ajay AK, Bhat MK.

J Cell Biochem. 2007 Apr 1;100(5):1191-9.

PMID:
17063488
26.

Methyl-beta-cyclodextrin enhances the susceptibility of human breast cancer cells to carboplatin and 5-fluorouracil: involvement of Akt, NF-kappaB and Bcl-2.

Upadhyay AK, Singh S, Chhipa RR, Vijayakumar MV, Ajay AK, Bhat MK.

Toxicol Appl Pharmacol. 2006 Oct 15;216(2):177-85. Epub 2006 May 19.

PMID:
16806341

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