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Items: 1 to 50 of 113

1.

Microbiota-derived acetate protects against respiratory syncytial virus infection through a GPR43-type 1 interferon response.

Antunes KH, Fachi JL, de Paula R, da Silva EF, Pral LP, Dos Santos AÁ, Dias GBM, Vargas JE, Puga R, Mayer FQ, Maito F, Zárate-Bladés CR, Ajami NJ, Sant'Ana MR, Candreva T, Rodrigues HG, Schmiele M, Silva Clerici MTP, Proença-Modena JL, Vieira AT, Mackay CR, Mansur D, Caballero MT, Marzec J, Li J, Wang X, Bell D, Polack FP, Kleeberger SR, Stein RT, Vinolo MAR, de Souza APD.

Nat Commun. 2019 Jul 22;10(1):3273. doi: 10.1038/s41467-019-11152-6.

2.

Dietary quality and the colonic mucosa-associated gut microbiome in humans.

Liu Y, Ajami NJ, El-Serag HB, Hair C, Graham DY, White DL, Chen L, Wang Z, Plew S, Kramer J, Cole R, Hernaez R, Hou J, Husain N, Jarbrink-Sehgal ME, Kanwal F, Ketwaroo G, Natarajan Y, Shah R, Velez M, Mallepally N, Petrosino JF, Jiao L.

Am J Clin Nutr. 2019 Sep 1;110(3):701-712. doi: 10.1093/ajcn/nqz139.

PMID:
31291462
3.

Exploration of the Vaginal and Gut Microbiome in African American Women by Body Mass Index, Class of Obesity, and Gestational Weight Gain: A Pilot Study.

Faucher MA, Greathouse KL, Hastings-Tolsma M, Padgett RN, Sakovich K, Choudhury A, Sheikh A, Ajami NJ, Petrosino JF.

Am J Perinatol. 2019 Jun 26. doi: 10.1055/s-0039-1692715. [Epub ahead of print]

PMID:
31242511
4.

Novel pan-serotype control RNA for dengue virus typing through real-time reverse transcription-polymerase chain reaction.

Álvarez-Díaz DA, Quintero PA, Peláez-Carvajal D, Ajami NJ, Usme-Ciro JA.

J Virol Methods. 2019 Sep;271:113677. doi: 10.1016/j.jviromet.2019.113677. Epub 2019 Jun 10.

PMID:
31195032
5.

Gut microbiome analysis by post: Evaluation of the optimal method to collect stool samples from infants within a national cohort study.

Williams GM, Leary SD, Ajami NJ, Chipper Keating S, Petrosin JF, Hamilton-Shield JP, Gillespie KM.

PLoS One. 2019 Jun 12;14(6):e0216557. doi: 10.1371/journal.pone.0216557. eCollection 2019.

6.

Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases.

Lloyd-Price J, Arze C, Ananthakrishnan AN, Schirmer M, Avila-Pacheco J, Poon TW, Andrews E, Ajami NJ, Bonham KS, Brislawn CJ, Casero D, Courtney H, Gonzalez A, Graeber TG, Hall AB, Lake K, Landers CJ, Mallick H, Plichta DR, Prasad M, Rahnavard G, Sauk J, Shungin D, Vázquez-Baeza Y, White RA 3rd; IBDMDB Investigators, Braun J, Denson LA, Jansson JK, Knight R, Kugathasan S, McGovern DPB, Petrosino JF, Stappenbeck TS, Winter HS, Clish CB, Franzosa EA, Vlamakis H, Xavier RJ, Huttenhower C.

Nature. 2019 May;569(7758):655-662. doi: 10.1038/s41586-019-1237-9. Epub 2019 May 29.

7.

Early nasal microbiota and acute respiratory infections during the first years of life.

Toivonen L, Hasegawa K, Waris M, Ajami NJ, Petrosino JF, Camargo CA Jr, Peltola V.

Thorax. 2019 Jun;74(6):592-599. doi: 10.1136/thoraxjnl-2018-212629. Epub 2019 May 10.

PMID:
31076501
8.

Molecular characterization of dengue virus reveals regional diversification of serotype 2 in Colombia.

Laiton-Donato K, Alvarez DA, Peláez-Carvajal D, Mercado M, Ajami NJ, Bosch I, Usme-Ciro JA.

Virol J. 2019 May 8;16(1):62. doi: 10.1186/s12985-019-1170-4.

9.

Gastric Microbiota in Helicobacter pylori-Negative and -Positive Gastritis Among High Incidence of Gastric Cancer Area.

Gantuya B, El-Serag HB, Matsumoto T, Ajami NJ, Oyuntsetseg K, Azzaya D, Uchida T, Yamaoka Y.

Cancers (Basel). 2019 Apr 10;11(4). pii: E504. doi: 10.3390/cancers11040504.

10.

PPARD and Interferon Gamma Promote Transformation of Gastric Progenitor Cells and Tumorigenesis in Mice.

Zuo X, Deguchi Y, Xu W, Liu Y, Li HS, Wei D, Tian R, Chen W, Xu M, Yang Y, Gao S, Jaoude JC, Liu F, Chrieki SP, Moussalli MJ, Gagea M, Sebastian MM, Zheng X, Tan D, Broaddus R, Wang J, Ajami NJ, Swennes AG, Watowich SS, Shureiqi I.

Gastroenterology. 2019 Jul;157(1):163-178. doi: 10.1053/j.gastro.2019.03.018. Epub 2019 Mar 15.

PMID:
30885780
11.

Frequency of Tongue Cleaning Impacts the Human Tongue Microbiome Composition and Enterosalivary Circulation of Nitrate.

Tribble GD, Angelov N, Weltman R, Wang BY, Eswaran SV, Gay IC, Parthasarathy K, Dao DV, Richardson KN, Ismail NM, Sharina IG, Hyde ER, Ajami NJ, Petrosino JF, Bryan NS.

Front Cell Infect Microbiol. 2019 Mar 1;9:39. doi: 10.3389/fcimb.2019.00039. eCollection 2019.

12.

Dietary Nutrients Involved in One-Carbon Metabolism and Colonic Mucosa-Associated Gut Microbiome in Individuals with an Endoscopically Normal Colon.

Gurwara S, Ajami NJ, Jang A, Hessel FC, Chen L, Plew S, Wang Z, Graham DY, Hair C, White DL, Kramer J, Kourkoumpetis T, Hoffman K, Cole R, Hou J, Husain N, Jarbrink-Sehgal M, Hernaez R, Kanwal F, Ketwaroo G, Shah R, Velez M, Natarajan Y, El-Serag HB, Petrosino JF, Jiao L.

Nutrients. 2019 Mar 13;11(3). pii: E613. doi: 10.3390/nu11030613.

13.

The NLRP3 inflammasome mediates DSS-induced intestinal inflammation in Nod2 knockout mice.

Umiker B, Lee HH, Cope J, Ajami NJ, Laine JP, Fregeau C, Ferguson H, Alves SE, Sciammetta N, Kleinschek M, Salmon M.

Innate Immun. 2019 Feb;25(2):132-143. doi: 10.1177/1753425919826367.

PMID:
30774010
14.

Expansion of Bacteriophages Is Linked to Aggravated Intestinal Inflammation and Colitis.

Gogokhia L, Buhrke K, Bell R, Hoffman B, Brown DG, Hanke-Gogokhia C, Ajami NJ, Wong MC, Ghazaryan A, Valentine JF, Porter N, Martens E, O'Connell R, Jacob V, Scherl E, Crawford C, Stephens WZ, Casjens SR, Longman RS, Round JL.

Cell Host Microbe. 2019 Feb 13;25(2):285-299.e8. doi: 10.1016/j.chom.2019.01.008.

PMID:
30763538
15.

Green Tea Polyphenols Modify the Gut Microbiome in db/db Mice as Co-Abundance Groups Correlating with the Blood Glucose Lowering Effect.

Chen T, Liu AB, Sun S, Ajami NJ, Ross MC, Wang H, Zhang L, Reuhl K, Kobayashi K, Onishi JC, Zhao L, Yang CS.

Mol Nutr Food Res. 2019 Apr;63(8):e1801064. doi: 10.1002/mnfr.201801064. Epub 2019 Jan 30.

PMID:
30667580
16.

Serum Metabolome Is Associated With the Nasopharyngeal Microbiota and Disease Severity Among Infants With Bronchiolitis.

Stewart CJ, Mansbach JM, Ajami NJ, Petrosino JF, Zhu Z, Liang L, Camargo CA, Hasegawa K.

J Infect Dis. 2019 May 24;219(12):2005-2014. doi: 10.1093/infdis/jiz021.

PMID:
30629185
17.

Human milk oligosaccharides, milk microbiome and infant gut microbiome modulate neonatal rotavirus infection.

Ramani S, Stewart CJ, Laucirica DR, Ajami NJ, Robertson B, Autran CA, Shinge D, Rani S, Anandan S, Hu L, Ferreon JC, Kuruvilla KA, Petrosino JF, Venkataram Prasad BV, Bode L, Kang G, Estes MK.

Nat Commun. 2018 Nov 27;9(1):5010. doi: 10.1038/s41467-018-07476-4.

18.

Safety and preliminary efficacy of orally administered lyophilized fecal microbiota product compared with frozen product given by enema for recurrent Clostridium difficile infection: A randomized clinical trial.

Jiang ZD, Jenq RR, Ajami NJ, Petrosino JF, Alexander AA, Ke S, Iqbal T, DuPont AW, Muldrew K, Shi Y, Peterson C, Do KA, DuPont HL.

PLoS One. 2018 Nov 2;13(11):e0205064. doi: 10.1371/journal.pone.0205064. eCollection 2018.

19.

Temporal development of the gut microbiome in early childhood from the TEDDY study.

Stewart CJ, Ajami NJ, O'Brien JL, Hutchinson DS, Smith DP, Wong MC, Ross MC, Lloyd RE, Doddapaneni H, Metcalf GA, Muzny D, Gibbs RA, Vatanen T, Huttenhower C, Xavier RJ, Rewers M, Hagopian W, Toppari J, Ziegler AG, She JX, Akolkar B, Lernmark A, Hyoty H, Vehik K, Krischer JP, Petrosino JF.

Nature. 2018 Oct;562(7728):583-588. doi: 10.1038/s41586-018-0617-x. Epub 2018 Oct 24.

20.

The human gut microbiome in early-onset type 1 diabetes from the TEDDY study.

Vatanen T, Franzosa EA, Schwager R, Tripathi S, Arthur TD, Vehik K, Lernmark Å, Hagopian WA, Rewers MJ, She JX, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Stewart CJ, Ajami NJ, Petrosino JF, Gevers D, Lähdesmäki H, Vlamakis H, Huttenhower C, Xavier RJ.

Nature. 2018 Oct;562(7728):589-594. doi: 10.1038/s41586-018-0620-2. Epub 2018 Oct 24.

21.

Prebiotics, Probiotics, and Acetate Supplementation Prevent Hypertension in a Model of Obstructive Sleep Apnea.

Ganesh BP, Nelson JW, Eskew JR, Ganesan A, Ajami NJ, Petrosino JF, Bryan RM Jr, Durgan DJ.

Hypertension. 2018 Nov;72(5):1141-1150. doi: 10.1161/HYPERTENSIONAHA.118.11695.

22.

Lung tissue microbial profile in lung cancer is distinct from emphysema.

Liu Y, O'Brien JL, Ajami NJ, Scheurer ME, Amirian ES, Armstrong G, Tsavachidis S, Thrift AP, Jiao L, Wong MC, Smith DP, Spitz MR, Bondy ML, Petrosino JF, Kheradmand F.

Am J Cancer Res. 2018 Sep 1;8(9):1775-1787. eCollection 2018.

23.

Circulating 25-hydroxyvitamin D, nasopharyngeal microbiota, and bronchiolitis severity.

Toivonen L, Hasegawa K, Ajami NJ, Celedón JC, Mansbach JM, Petrosino JF, Camargo CA Jr.

Pediatr Allergy Immunol. 2018 Dec;29(8):877-880. doi: 10.1111/pai.12977. Epub 2018 Nov 13. No abstract available.

PMID:
30152883
24.

Correction: Effects of tobacco smoke and electronic cigarette vapor exposure on the oral and gut microbiota in humans: a pilot study.

Stewart CJ, Auchtung TA, Ajami NJ, Velasquez K, Smith DP, De La Garza R 2nd, Salas R, Petrosino JF.

PeerJ. 2018 Aug 23;6. pii: e4693/correction-1. doi: 10.7717/peerj.4693/correction-1. eCollection 2018.

25.

Differential effects of selective and non-selective cyclooxygenase inhibitors on fecal microbiota in adult horses.

Whitfield-Cargile CM, Chamoun-Emanuelli AM, Cohen ND, Richardson LM, Ajami NJ, Dockery HJ.

PLoS One. 2018 Aug 23;13(8):e0202527. doi: 10.1371/journal.pone.0202527. eCollection 2018.

26.

Schistosoma mansoni infection is associated with quantitative and qualitative modifications of the mammalian intestinal microbiota.

Jenkins TP, Peachey LE, Ajami NJ, MacDonald AS, Hsieh MH, Brindley PJ, Cantacessi C, Rinaldi G.

Sci Rep. 2018 Aug 13;8(1):12072. doi: 10.1038/s41598-018-30412-x.

27.

Maximal viral information recovery from sequence data using VirMAP.

Ajami NJ, Wong MC, Ross MC, Lloyd RE, Petrosino JF.

Nat Commun. 2018 Aug 10;9(1):3205. doi: 10.1038/s41467-018-05658-8.

28.

Analysis of Fish Commonly Sold in Local Supermarkets Reveals the Presence of Pathogenic and Multidrug-Resistant Bacterial Communities.

Okyere A, Bishoff D, Oyaro MO, Ajami NJ, Darkoh C.

Microbiol Insights. 2018 Jul 18;11:1178636118786925. doi: 10.1177/1178636118786925. eCollection 2018.

29.

Gut microbiota components are associated with fixed airway obstruction in asthmatic patients living in the tropics.

Buendía E, Zakzuk J, San-Juan-Vergara H, Zurek E, Ajami NJ, Caraballo L.

Sci Rep. 2018 Jun 25;8(1):9582. doi: 10.1038/s41598-018-27964-3.

30.

Effects of tobacco smoke and electronic cigarette vapor exposure on the oral and gut microbiota in humans: a pilot study.

Stewart CJ, Auchtung TA, Ajami NJ, Velasquez K, Smith DP, De La Garza R 2nd, Salas R, Petrosino JF.

PeerJ. 2018 Apr 30;6:e4693. doi: 10.7717/peerj.4693. eCollection 2018. Erratum in: PeerJ. 2018 Aug 23;6:.

31.

Age-related changes in the gut microbiota influence systemic inflammation and stroke outcome.

Spychala MS, Venna VR, Jandzinski M, Doran SJ, Durgan DJ, Ganesh BP, Ajami NJ, Putluri N, Graf J, Bryan RM, McCullough LD.

Ann Neurol. 2018 Jul;84(1):23-36. doi: 10.1002/ana.25250. Epub 2018 Jul 18.

32.

Oral microbiota reveals signs of acculturation in Mexican American women.

Hoffman KL, Hutchinson DS, Fowler J, Smith DP, Ajami NJ, Zhao H, Scheet P, Chow WH, Petrosino JF, Daniel CR.

PLoS One. 2018 Apr 25;13(4):e0194100. doi: 10.1371/journal.pone.0194100. eCollection 2018.

33.

Potent Sodium/Glucose Cotransporter SGLT1/2 Dual Inhibition Improves Glycemic Control Without Marked Gastrointestinal Adaptation or Colonic Microbiota Changes in Rodents.

Du F, Hinke SA, Cavanaugh C, Polidori D, Wallace N, Kirchner T, Jennis M, Lang W, Kuo GH, Gaul MD, Lenhard J, Demarest K, Ajami NJ, Liang Y, Hornby PJ.

J Pharmacol Exp Ther. 2018 Jun;365(3):676-687. doi: 10.1124/jpet.118.248575. Epub 2018 Apr 19.

PMID:
29674332
34.

Antibiotic-mediated bacteriome depletion in ApcMin/+ mice is associated with reduction in mucus-producing goblet cells and increased colorectal cancer progression.

Kaur K, Saxena A, Debnath I, O'Brien JL, Ajami NJ, Auchtung TA, Petrosino JF, Sougiannis AJ, Depaep S, Chumanevich A, Gummadidala PM, Omebeyinje MH, Banerjee S, Chatzistamou I, Chakraborty P, Fayad R, Berger FG, Carson JA, Chanda A.

Cancer Med. 2018 May;7(5):2003-2012. doi: 10.1002/cam4.1460. Epub 2018 Apr 6.

35.

Investigating Colonization of the Healthy Adult Gastrointestinal Tract by Fungi.

Auchtung TA, Fofanova TY, Stewart CJ, Nash AK, Wong MC, Gesell JR, Auchtung JM, Ajami NJ, Petrosino JF.

mSphere. 2018 Mar 28;3(2). pii: e00092-18. doi: 10.1128/mSphere.00092-18. eCollection 2018 Mar-Apr.

36.

A Lachnospiraceae-dominated bacterial signature in the fecal microbiota of HIV-infected individuals from Colombia, South America.

San-Juan-Vergara H, Zurek E, Ajami NJ, Mogollon C, Peña M, Portnoy I, Vélez JI, Cadena-Cruz C, Diaz-Olmos Y, Hurtado-Gómez L, Sanchez-Sit S, Hernández D, Urruchurtu I, Di-Ruggiero P, Guardo-García E, Torres N, Vidal-Orjuela O, Viasus D, Petrosino JF, Cervantes-Acosta G.

Sci Rep. 2018 Mar 14;8(1):4479. doi: 10.1038/s41598-018-22629-7.

37.

Influence of fecal collection conditions and 16S rRNA gene sequencing at two centers on human gut microbiota analysis.

Penington JS, Penno MAS, Ngui KM, Ajami NJ, Roth-Schulze AJ, Wilcox SA, Bandala-Sanchez E, Wentworth JM, Barry SC, Brown CY, Couper JJ, Petrosino JF, Papenfuss AT, Harrison LC; ENDIA Study Group*.

Sci Rep. 2018 Mar 12;8(1):4386. doi: 10.1038/s41598-018-22491-7.

38.

Arginine Metabolism Is Altered in Adults with A-β + Ketosis-Prone Diabetes.

Mulukutla SN, Hsu JW, Gaba R, Bohren KM, Guthikonda A, Iyer D, Ajami NJ, Petrosino JF, Hampe CS, Ram N, Jahoor F, Balasubramanyam A.

J Nutr. 2018 Feb 1;148(2):185-193. doi: 10.1093/jn/nxx032.

39.

Impact of Oral Fidaxomicin Administration on the Intestinal Microbiota and Susceptibility to Clostridium difficile Colonization in Mice.

Ajami NJ, Cope JL, Wong MC, Petrosino JF, Chesnel L.

Antimicrob Agents Chemother. 2018 Apr 26;62(5). pii: e02112-17. doi: 10.1128/AAC.02112-17. Print 2018 May.

40.

The association between anterior nares and nasopharyngeal microbiota in infants hospitalized for bronchiolitis.

Luna PN, Hasegawa K, Ajami NJ, Espinola JA, Henke DM, Petrosino JF, Piedra PA, Sullivan AF, Camargo CA Jr, Shaw CA, Mansbach JM.

Microbiome. 2018 Jan 3;6(1):2. doi: 10.1186/s40168-017-0385-0.

41.

Respiratory Syncytial Virus and Rhinovirus Bronchiolitis Are Associated With Distinct Metabolic Pathways.

Stewart CJ, Hasegawa K, Wong MC, Ajami NJ, Petrosino JF, Piedra PA, Espinola JA, Tierney CN, Camargo CA Jr, Mansbach JM.

J Infect Dis. 2018 Mar 13;217(7):1160-1169. doi: 10.1093/infdis/jix680.

42.

Successful collection of stool samples for microbiome analyses from a large community-based population of elderly men.

Abrahamson M, Hooker E, Ajami NJ, Petrosino JF, Orwoll ES.

Contemp Clin Trials Commun. 2017 Sep;7:158-162. doi: 10.1016/j.conctc.2017.07.002. Epub 2017 Jul 6.

43.

The gut mycobiome of the Human Microbiome Project healthy cohort.

Nash AK, Auchtung TA, Wong MC, Smith DP, Gesell JR, Ross MC, Stewart CJ, Metcalf GA, Muzny DM, Gibbs RA, Ajami NJ, Petrosino JF.

Microbiome. 2017 Nov 25;5(1):153. doi: 10.1186/s40168-017-0373-4.

44.

Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients.

Gopalakrishnan V, Spencer CN, Nezi L, Reuben A, Andrews MC, Karpinets TV, Prieto PA, Vicente D, Hoffman K, Wei SC, Cogdill AP, Zhao L, Hudgens CW, Hutchinson DS, Manzo T, Petaccia de Macedo M, Cotechini T, Kumar T, Chen WS, Reddy SM, Szczepaniak Sloane R, Galloway-Pena J, Jiang H, Chen PL, Shpall EJ, Rezvani K, Alousi AM, Chemaly RF, Shelburne S, Vence LM, Okhuysen PC, Jensen VB, Swennes AG, McAllister F, Marcelo Riquelme Sanchez E, Zhang Y, Le Chatelier E, Zitvogel L, Pons N, Austin-Breneman JL, Haydu LE, Burton EM, Gardner JM, Sirmans E, Hu J, Lazar AJ, Tsujikawa T, Diab A, Tawbi H, Glitza IC, Hwu WJ, Patel SP, Woodman SE, Amaria RN, Davies MA, Gershenwald JE, Hwu P, Lee JE, Zhang J, Coussens LM, Cooper ZA, Futreal PA, Daniel CR, Ajami NJ, Petrosino JF, Tetzlaff MT, Sharma P, Allison JP, Jenq RR, Wargo JA.

Science. 2018 Jan 5;359(6371):97-103. doi: 10.1126/science.aan4236. Epub 2017 Nov 2.

45.

Wild Mouse Gut Microbiota Promotes Host Fitness and Improves Disease Resistance.

Rosshart SP, Vassallo BG, Angeletti D, Hutchinson DS, Morgan AP, Takeda K, Hickman HD, McCulloch JA, Badger JH, Ajami NJ, Trinchieri G, Pardo-Manuel de Villena F, Yewdell JW, Rehermann B.

Cell. 2017 Nov 16;171(5):1015-1028.e13. doi: 10.1016/j.cell.2017.09.016. Epub 2017 Oct 19.

46.

Complete Genome Sequence of Vibrio gazogenes ATCC 43942.

Gummadidala PM, Holder ME, O'Brien JL, Ajami NJ, Petrosino JF, Mitra C, Chen YP, Decho AW, Chanda A.

Genome Announc. 2017 Jul 27;5(30). pii: e00733-17. doi: 10.1128/genomeA.00733-17.

47.

Sphingolipid metabolism potential in fecal microbiome and bronchiolitis in infants: a case-control study.

Hasegawa K, Stewart CJ, Mansbach JM, Linnemann RW, Ajami NJ, Petrosino JF, Camargo CA.

BMC Res Notes. 2017 Jul 26;10(1):325. doi: 10.1186/s13104-017-2659-9.

48.

Impact of environmental microbiota on human microbiota of workers in academic mouse research facilities: An observational study.

Lai PS, Allen JG, Hutchinson DS, Ajami NJ, Petrosino JF, Winters T, Hug C, Wartenberg GR, Vallarino J, Christiani DC.

PLoS One. 2017 Jul 13;12(7):e0180969. doi: 10.1371/journal.pone.0180969. eCollection 2017.

49.

Serum LL-37 Levels Associated With Severity of Bronchiolitis and Viral Etiology.

Mansbach JM, Hasegawa K, Ajami NJ, Petrosino JF, Piedra PA, Tierney CN, Espinola JA, Camargo CA.

Clin Infect Dis. 2017 Sep 15;65(6):967-975. doi: 10.1093/cid/cix483.

50.

Associations of Nasopharyngeal Metabolome and Microbiome with Severity among Infants with Bronchiolitis. A Multiomic Analysis.

Stewart CJ, Mansbach JM, Wong MC, Ajami NJ, Petrosino JF, Camargo CA Jr, Hasegawa K.

Am J Respir Crit Care Med. 2017 Oct 1;196(7):882-891. doi: 10.1164/rccm.201701-0071OC.

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