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Items: 1 to 50 of 170


Neuroimaging of Small Vessel Disease in Late-Life Depression.

Farhat NS, Theiss R, Santini T, Ibrahim TS, Aizenstein HJ.

Adv Exp Med Biol. 2019;1192:95-115. doi: 10.1007/978-981-32-9721-0_5.


Activity patterns related to depression symptoms in stressed dementia caregivers.

Smagula SF, Hasler BP, Schulz R, Graves JL, Reynolds CF, Aizenstein HJ, Buysse DJ, Krafty RT, Hall MH.

Int Psychogeriatr. 2019 Oct 29:1-8. doi: 10.1017/S1041610219001601. [Epub ahead of print]


Effects of soy isoflavones on cognitive function: a systematic review and meta-analysis of randomized controlled trials.

Cui C, Birru RL, Snitz BE, Ihara M, Kakuta C, Lopresti BJ, Aizenstein HJ, Lopez OL, Mathis CA, Miyamoto Y, Kuller LH, Sekikawa A.

Nutr Rev. 2019 Sep 4. pii: nuz050. doi: 10.1093/nutrit/nuz050. [Epub ahead of print]


Disruption of Neural Homeostasis as a Model of Relapse and Recurrence in Late-Life Depression.

Andreescu C, Ajilore O, Aizenstein HJ, Albert K, Butters MA, Landman BA, Karim HT, Krafty R, Taylor WD.

Am J Geriatr Psychiatry. 2019 Dec;27(12):1316-1330. doi: 10.1016/j.jagp.2019.07.016. Epub 2019 Aug 7. Review.


Relationships Between Executive Control Circuit Activity, Amyloid Burden, and Education in Cognitively Healthy Older Adults.

Karim HT, Tudorascu DL, Cohen A, Price JC, Lopresti B, Mathis C, Klunk W, Snitz BE, Aizenstein HJ.

Am J Geriatr Psychiatry. 2019 Dec;27(12):1360-1371. doi: 10.1016/j.jagp.2019.07.008. Epub 2019 Jul 19.


Regional Gray Matter Volume Links Rest-Activity Rhythm Fragmentation With Past Cognitive Decline.

Smagula SF, Chahine L, Metti A, Rangarajan A, Aizenstein HJ, Tian Q, Rosano C.

Am J Geriatr Psychiatry. 2019 Jul 19. pii: S1064-7481(19)30438-5. doi: 10.1016/j.jagp.2019.07.009. [Epub ahead of print]


When worry may be good for you: Worry severity and limbic-prefrontal functional connectivity in late-life generalized anxiety disorder.

Wu M, Mennin DS, Ly M, Karim HT, Banihashemi L, Tudorascu DL, Aizenstein HJ, Andreescu C.

J Affect Disord. 2019 Oct 1;257:650-657. doi: 10.1016/j.jad.2019.07.022. Epub 2019 Jul 5.


Incorporating prior information with fused sparse group lasso: Application to prediction of clinical measures from neuroimages.

Beer JC, Aizenstein HJ, Anderson SJ, Krafty RT.

Biometrics. 2019 Apr 25. doi: 10.1111/biom.13075. [Epub ahead of print]


Association Between Amyloid-β, Small-vessel Disease, and Neurodegeneration Biomarker Positivity, and Progression to Mild Cognitive Impairment in Cognitively Normal Individuals.

Nadkarni NK, Tudorascu D, Campbell E, Snitz BE, Cohen AD, Halligan E, Mathis CA, Aizenstein HJ, Klunk WE.

J Gerontol A Biol Sci Med Sci. 2019 Oct 4;74(11):1753-1760. doi: 10.1093/gerona/glz088.


Training the Next Generation of Geriatric-Focused Clinical Neuroscientists.

Manning KJ, Gunning FM, Aizenstein HJ, Steffens DC.

Am J Geriatr Psychiatry. 2019 Jul;27(7):720-727. doi: 10.1016/j.jagp.2019.03.006. Epub 2019 Mar 13.


Physical Activity and Cerebral Small Vein Integrity in Older Adults.

Shaaban CE, Aizenstein HJ, Jorgensen DR, Mahbubani RLM, Meckes NA, Erickson KI, Glynn NW, Mettenburg J, Guralnik J, Newman AB, Ibrahim TS, Laurienti PJ, Vallejo AN, Rosano C.

Med Sci Sports Exerc. 2019 Aug;51(8):1684-1691. doi: 10.1249/MSS.0000000000001952.


Amyloid deposition is associated with different patterns of hippocampal connectivity in men versus women.

Wu M, Thurston RC, Tudorascu DL, Karim HT, Mathis CA, Lopresti BJ, Kamboh MI, Cohen AD, Snitz BE, Klunk WE, Aizenstein HJ.

Neurobiol Aging. 2019 Apr;76:141-150. doi: 10.1016/j.neurobiolaging.2018.11.020. Epub 2018 Dec 1.


Low-dose augmentation with buprenorphine increases emotional reactivity but not reward activity in treatment resistant mid- and late-life depression.

Lin C, Karim HT, Pecina M, Aizenstein HJ, Lenze EJ, Blumberger DM, Mulsant BH, Kharasch ED, Reynolds Iii CF, Karp JF.

Neuroimage Clin. 2019;21:101679. doi: 10.1016/j.nicl.2019.101679. Epub 2019 Jan 22.


Computational and experimental evaluation of the Tic-Tac-Toe RF coil for 7 Tesla MRI.

Krishnamurthy N, Santini T, Wood S, Kim J, Zhao T, Aizenstein HJ, Ibrahim TS.

PLoS One. 2019 Jan 10;14(1):e0209663. doi: 10.1371/journal.pone.0209663. eCollection 2019.


A Homeostatic Model of Subjective Cognitive Decline.

Mizuno A, Ly M, Aizenstein HJ.

Brain Sci. 2018 Dec 19;8(12). pii: E228. doi: 10.3390/brainsci8120228. Review.


Depressive symptoms and cerebral microvascular disease in adults with Type 1 diabetes mellitus.

Nunley KA, Karp JF, Orchard TJ, Costacou T, Aizenstein HJ, Jennings JR, Rosano C.

Diabet Med. 2019 Sep;36(9):1168-1175. doi: 10.1111/dme.13879. Epub 2019 Jan 18.


In-vivo and numerical analysis of the eigenmodes produced by a multi-level Tic-Tac-Toe head transmit array for 7 Tesla MRI.

Santini T, Zhao Y, Wood S, Krishnamurthy N, Kim J, Farhat N, Alkhateeb S, Martins T, Koo M, Zhao T, Aizenstein HJ, Ibrahim TS.

PLoS One. 2018 Nov 27;13(11):e0206127. doi: 10.1371/journal.pone.0206127. eCollection 2018.


Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging.

Yan Q, Nho K, Del-Aguila JL, Wang X, Risacher SL, Fan KH, Snitz BE, Aizenstein HJ, Mathis CA, Lopez OL, Demirci FY, Feingold E, Klunk WE, Saykin AJ; Alzheimer’s Disease Neuroimaging Initiative (ADNI), Cruchaga C, Kamboh MI.

Mol Psychiatry. 2018 Oct 25. doi: 10.1038/s41380-018-0246-7. [Epub ahead of print]


Comparison of longitudinal Aβ in nondemented elderly and Down syndrome.

Tudorascu DL, Anderson SJ, Minhas DS, Yu Z, Comer D, Lao P, Hartley S, Laymon CM, Snitz BE, Lopresti BJ, Johnson S, Price JC, Mathis CA, Aizenstein HJ, Klunk WE, Handen BL, Christian BT, Cohen AD.

Neurobiol Aging. 2019 Jan;73:171-176. doi: 10.1016/j.neurobiolaging.2018.09.030. Epub 2018 Sep 27.


Trajectories in Cerebral Blood Flow Following Antidepressant Treatment in Late-Life Depression: Support for the Vascular Depression Hypothesis.

Wei W, Karim HT, Lin C, Mizuno A, Andreescu C, Karp JF, Reynolds CF 3rd, Aizenstein HJ.

J Clin Psychiatry. 2018 Oct 23;79(6). pii: 18m12106. doi: 10.4088/JCP.18m12106.


Sleep moderates the relationship between amyloid beta and memory recall.

Wilckens KA, Tudorascu DL, Snitz BE, Price JC, Aizenstein HJ, Lopez OL, Erickson KI, Lopresti BJ, Laymon CM, Minhas D, Mathis CA, Buysse DJ, Klunk WE, Cohen AD.

Neurobiol Aging. 2018 Nov;71:142-148. doi: 10.1016/j.neurobiolaging.2018.07.011. Epub 2018 Jul 26.


Acute trajectories of neural activation predict remission to pharmacotherapy in late-life depression.

Karim HT, Wang M, Andreescu C, Tudorascu D, Butters MA, Karp JF, Reynolds CF 3rd, Aizenstein HJ.

Neuroimage Clin. 2018 Jun 8;19:831-839. doi: 10.1016/j.nicl.2018.06.006. eCollection 2018.


Amyloid deposition and brain structure as long-term predictors of MCI, dementia, and mortality.

Lopez OL, Becker JT, Chang Y, Klunk WE, Mathis C, Price J, Aizenstein HJ, Snitz B, Cohen AD, DeKosky ST, Ikonomovic M, Kamboh MI, Kuller LH.

Neurology. 2018 May 22;90(21):e1920-e1928. doi: 10.1212/WNL.0000000000005549. Epub 2018 Apr 25.


Association of Hippocampal Substructure Resting-State Functional Connectivity with Memory Performance in Older Adults.

Smagula SF, Karim HT, Rangarajan A, Santos FP, Wood SC, Santini T, Jakicic JM, Reynolds CF 3rd, Cameron JL, Vallejo AN, Butters MA, Rosano C, Ibrahim TS, Erickson KI, Aizenstein HJ.

Am J Geriatr Psychiatry. 2018 Jun;26(6):690-699. doi: 10.1016/j.jagp.2018.03.003. Epub 2018 Mar 13.


Long-term changes in retinal vascular diameter and cognitive impairment in type 1 diabetes.

Nunley KA, Metti AL, Klein R, Klein BE, Saxton JA, Orchard TJ, Costacou T, Aizenstein HJ, Rosano C.

Diab Vasc Dis Res. 2018 May;15(3):223-232. doi: 10.1177/1479164118758581. Epub 2018 Feb 28.


Insulin sensitivity predicts brain network connectivity following a meal.

Ryan JP, Karim HT, Aizenstein HJ, Helbling NL, Toledo FGS.

Neuroimage. 2018 May 1;171:268-276. doi: 10.1016/j.neuroimage.2018.01.024. Epub 2018 Jan 13.


Vascular and dopaminergic contributors to mild parkinsonian signs in older adults.

Rosso AL, Bohnen NI, Launer LJ, Aizenstein HJ, Yaffe K, Rosano C.

Neurology. 2018 Jan 16;90(3):e223-e229. doi: 10.1212/WNL.0000000000004842. Epub 2017 Dec 15.


Basal ganglia cerebral blood flow associates with psychomotor speed in adults with type 1 diabetes.

Ryan JP, Aizenstein HJ, Orchard TJ, Nunley KA, Karim H, Rosano C.

Brain Imaging Behav. 2018 Oct;12(5):1271-1278. doi: 10.1007/s11682-017-9783-y.


Amyloid β Deposition and Suspected Non-Alzheimer Pathophysiology and Cognitive Decline Patterns for 12 Years in Oldest Old Participants Without Dementia.

Zhao Y, Tudorascu DL, Lopez OL, Cohen AD, Mathis CA, Aizenstein HJ, Price JC, Kuller LH, Kamboh MI, DeKosky ST, Klunk WE, Snitz BE.

JAMA Neurol. 2018 Jan 1;75(1):88-96. doi: 10.1001/jamaneurol.2017.3029.


The Multi-Faceted Relationship between White Matter Lesions and Late-Life Depression.

Wu M, Aizenstein HJ.

Am J Geriatr Psychiatry. 2017 Dec;25(12):1322-1325. doi: 10.1016/j.jagp.2017.09.017. Epub 2017 Sep 21. No abstract available.


In the grip of worry: cerebral blood flow changes during worry induction and reappraisal in late-life generalized anxiety disorder.

Karim HT, Tudorascu DL, Butters MA, Walker S, Aizenstein HJ, Andreescu C.

Transl Psychiatry. 2017 Sep 26;7(9):e1244. doi: 10.1038/tp.2017.215.


Association between change in brain gray matter volume, cognition, and depression severity: Pre- and post- antidepressant pharmacotherapy for late-life depression.

Droppa K, Karim HT, Tudorascu DL, Karp JF, Reynolds CF 3rd, Aizenstein HJ, Butters MA.

J Psychiatr Res. 2017 Dec;95:129-134. doi: 10.1016/j.jpsychires.2017.08.002. Epub 2017 Aug 8.


In the grip of worry: cerebral blood flow changes during worry induction and reappraisal in late-life generalized anxiety disorder.

Karim HT, Tudorascu DL, Butters MA, Walker S, Aizenstein HJ, Andreescu C.

Transl Psychiatry. 2017 Aug 15;7(8):e1204. doi: 10.1038/tp.2017.180. Erratum in: Transl Psychiatry. 2017 Sep 26;7(9):e1244.


In Vivo Imaging of Venous Side Cerebral Small-Vessel Disease in Older Adults: An MRI Method at 7T.

Shaaban CE, Aizenstein HJ, Jorgensen DR, MacCloud RL, Meckes NA, Erickson KI, Glynn NW, Mettenburg J, Guralnik J, Newman AB, Ibrahim TS, Laurienti PJ, Vallejo AN, Rosano C; LIFE Study Group.

AJNR Am J Neuroradiol. 2017 Oct;38(10):1923-1928. doi: 10.3174/ajnr.A5327. Epub 2017 Aug 3. Erratum in: AJNR Am J Neuroradiol. 2018 Dec;39(12):E132.


Slowing gait and risk for cognitive impairment: The hippocampus as a shared neural substrate.

Rosso AL, Verghese J, Metti AL, Boudreau RM, Aizenstein HJ, Kritchevsky S, Harris T, Yaffe K, Satterfield S, Studenski S, Rosano C.

Neurology. 2017 Jul 25;89(4):336-342. doi: 10.1212/WNL.0000000000004153. Epub 2017 Jun 28.


Long-term changes in time spent walking and subsequent cognitive and structural brain changes in older adults.

Best JR, Rosano C, Aizenstein HJ, Tian Q, Boudreau RM, Ayonayon HN, Satterfield S, Simonsick EM, Studenski S, Yaffe K, Liu-Ambrose T; Health, Aging and Body Composition Study.

Neurobiol Aging. 2017 Sep;57:153-161. doi: 10.1016/j.neurobiolaging.2017.05.023. Epub 2017 Jun 6.


Corrigendum to "Brain Activation and Psychomotor Speed in Middle-Aged Patients with Type 1 Diabetes: Relationships with Hyperglycemia and Brain Small Vessel Disease".

Hwang M, Tudorascu DL, Nunley K, Karim H, Aizenstein HJ, Orchard TJ, Rosano C.

J Diabetes Res. 2017;2017:4295645. doi: 10.1155/2017/4295645. Epub 2017 Mar 16.


Physical activity and hippocampal volume in middle-aged patients with type 1 diabetes.

Nunley KA, Leckie RL, Orchard TJ, Costacou T, Aizenstein HJ, Jennings JR, Erickson KI, Rosano C.

Neurology. 2017 Apr 18;88(16):1564-1570. doi: 10.1212/WNL.0000000000003805. Epub 2017 Mar 10.


Regional Gray Matter Volumes as Related to Psychomotor Slowing in Adults with Type 1 Diabetes.

Nunley KA, Ryan CM, Aizenstein HJ, Jennings JR, MacCloud RL, Orchard TJ, Rosano C.

Psychosom Med. 2017 Jun;79(5):533-540. doi: 10.1097/PSY.0000000000000449.


Hippocampal Response to a 24-Month Physical Activity Intervention in Sedentary Older Adults.

Rosano C, Guralnik J, Pahor M, Glynn NW, Newman AB, Ibrahim TS, Erickson K, Cohen R, Shaaban CE, MacCloud RL, Aizenstein HJ.

Am J Geriatr Psychiatry. 2017 Mar;25(3):209-217. doi: 10.1016/j.jagp.2016.11.007. Epub 2016 Nov 15.


Reproducibility and Bias in Healthy Brain Segmentation: Comparison of Two Popular Neuroimaging Platforms.

Tudorascu DL, Karim HT, Maronge JM, Alhilali L, Fakhran S, Aizenstein HJ, Muschelli J, Crainiceanu CM.

Front Neurosci. 2016 Nov 9;10:503. eCollection 2016.


Enhanced Molecular Aging in Late-Life Depression: the Senescent-Associated Secretory Phenotype.

Diniz BS, Reynolds CF 3rd, Sibille E, Lin CW, Tseng G, Lotrich F, Aizenstein HJ, Butters MA.

Am J Geriatr Psychiatry. 2017 Jan;25(1):64-72. doi: 10.1016/j.jagp.2016.08.018. Epub 2016 Aug 31.


Vascular depression consensus report - a critical update.

Aizenstein HJ, Baskys A, Boldrini M, Butters MA, Diniz BS, Jaiswal MK, Jellinger KA, Kruglov LS, Meshandin IA, Mijajlovic MD, Niklewski G, Pospos S, Raju K, Richter K, Steffens DC, Taylor WD, Tene O.

BMC Med. 2016 Nov 3;14(1):161.


Gray matter regions statistically mediating the cross-sectional association of eotaxin and set-shifting among older adults with major depressive disorder.

Smagula SF, Karim HT, Lenze EJ, Butters MA, Wu GF, Mulsant BH, Reynolds CF, Aizenstein HJ.

Int J Geriatr Psychiatry. 2017 Dec;32(12):1226-1232. doi: 10.1002/gps.4585. Epub 2016 Sep 19.


Sleep-Wake Differences in Relative Regional Cerebral Metabolic Rate for Glucose among Patients with Insomnia Compared with Good Sleepers.

Kay DB, Karim HT, Soehner AM, Hasler BP, Wilckens KA, James JA, Aizenstein HJ, Price JC, Rosario BL, Kupfer DJ, Germain A, Hall MH, Franzen PL, Nofzinger EA, Buysse DJ.

Sleep. 2016 Oct 1;39(10):1779-1794.


Circulating biosignatures of late-life depression (LLD): Towards a comprehensive, data-driven approach to understanding LLD pathophysiology.

Diniz BS, Lin CW, Sibille E, Tseng G, Lotrich F, Aizenstein HJ, Reynolds CF, Butters MA.

J Psychiatr Res. 2016 Nov;82:1-7. doi: 10.1016/j.jpsychires.2016.07.006. Epub 2016 Jul 11.


Brain structural connectivity in late-life major depressive disorder.

Smagula SF, Aizenstein HJ.

Biol Psychiatry Cogn Neurosci Neuroimaging. 2016 May;1(3):271-277.


Brain Amyloidosis and Triglycerides: Preventing Alzheimer Disease Pathology by Treating Vascular Disease?

Cohen AD, Aizenstein HJ.

Am J Geriatr Psychiatry. 2016 Aug;24(8):613-614. doi: 10.1016/j.jagp.2016.04.007. Epub 2016 Apr 27. No abstract available.


Immunological biomarkers associated with brain structure and executive function in late-life depression: exploratory pilot study.

Smagula SF, Lotrich FE, Aizenstein HJ, Diniz BS, Krystek J, Wu GF, Mulsant BH, Butters MA, Reynolds CF 3rd, Lenze EJ.

Int J Geriatr Psychiatry. 2017 Jun;32(6):692-699. doi: 10.1002/gps.4512. Epub 2016 Jun 10.


The effects of white matter disease on the accuracy of automated segmentation.

Karim HT, Andreescu C, MacCloud RL, Butters MA, Reynolds CF 3rd, Aizenstein HJ, Tudorascu DL.

Psychiatry Res Neuroimaging. 2016 Jul 30;253:7-14. doi: 10.1016/j.pscychresns.2016.05.003. Epub 2016 May 19.

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