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Items: 1 to 50 of 103

1.

Establishment of infectious genotype 4 cell culture-derived hepatitis C virus.

Watanabe N, Suzuki T, Date T, Hussan HA, Hmwe SS, Aizaki H, Sugiyama M, Mizokami M, Delaney Iv W, Cheng G, Muramatsu M, Wakita T.

J Gen Virol. 2020 Feb;101(2):188-197. doi: 10.1099/jgv.0.001378. Epub 2019 Dec 20.

PMID:
31859613
2.

The machinery for endocytosis of epidermal growth factor receptor coordinates the transport of incoming hepatitis B virus to the endosomal network.

Iwamoto M, Saso W, Nishioka K, Ohashi H, Sugiyama R, Ryo A, Ohki M, Yun JH, Park SY, Ohshima T, Suzuki R, Aizaki H, Muramatsu M, Matano T, Iwami S, Sureau C, Wakita T, Watashi K.

J Biol Chem. 2020 Jan 17;295(3):800-807. doi: 10.1074/jbc.AC119.010366. Epub 2019 Dec 12.

PMID:
31836663
3.

Non-nucleoside hepatitis B virus polymerase inhibitors identified by an in vitro polymerase elongation assay.

Nakajima S, Watashi K, Fukano K, Tsukuda S, Wakae K, Aizaki H, Muramatsu M, Wakita T, Toyoda T.

J Gastroenterol. 2020 Apr;55(4):441-452. doi: 10.1007/s00535-019-01643-0. Epub 2019 Nov 25.

PMID:
31768802
4.

Surfeit 4 Contributes to the Replication of Hepatitis C Virus Using Double-Membrane Vesicles.

Kong L, Aoyagi H, Yang Z, Ouyang T, Matsuda M, Fujimoto A, Watashi K, Suzuki R, Arita M, Yamagoe S, Dohmae N, Suzuki T, Suzuki T, Muramatsu M, Wakita T, Aizaki H.

J Virol. 2020 Jan 6;94(2). pii: e00858-19. doi: 10.1128/JVI.00858-19. Print 2020 Jan 6.

PMID:
31645450
5.

Ledipasvir and Sofosbuvir for Acute Hepatitis C Virus Monoinfection Associated with a High Risk of Acute Liver Failure.

Hatanaka T, Naganuma A, Tateyama Y, Yoshinari F, Hoshino T, Sato K, Hmwe SS, Aizaki H, Wakita T, Kakizaki S, Uraoka T.

Intern Med. 2019 Oct 15;58(20):2969-2975. doi: 10.2169/internalmedicine.2982-19. Epub 2019 Jun 27.

6.

Epidermal growth factor receptor is a host-entry cofactor triggering hepatitis B virus internalization.

Iwamoto M, Saso W, Sugiyama R, Ishii K, Ohki M, Nagamori S, Suzuki R, Aizaki H, Ryo A, Yun JH, Park SY, Ohtani N, Muramatsu M, Iwami S, Tanaka Y, Sureau C, Wakita T, Watashi K.

Proc Natl Acad Sci U S A. 2019 Apr 23;116(17):8487-8492. doi: 10.1073/pnas.1811064116. Epub 2019 Apr 5.

7.

Activation of protein kinase R by hepatitis C virus RNA-dependent RNA polymerase.

Suzuki R, Matsuda M, Shimoike T, Watashi K, Aizaki H, Kato T, Suzuki T, Muramatsu M, Wakita T.

Virology. 2019 Mar;529:226-233. doi: 10.1016/j.virol.2019.01.024. Epub 2019 Jan 29.

8.

Regulation of Hepatitis C Virus Infection by Cellular Retinoic Acid Binding Proteins through the Modulation of Lipid Droplet Abundance.

Bang BR, Li M, Tsai KN, Aoyagi H, Lee SA, Machida K, Aizaki H, Jung JU, Ou JJ, Saito T.

J Virol. 2019 Apr 3;93(8). pii: e02302-18. doi: 10.1128/JVI.02302-18. Print 2019 Apr 15.

9.

Troglitazone Impedes the Oligomerization of Sodium Taurocholate Cotransporting Polypeptide and Entry of Hepatitis B Virus Into Hepatocytes.

Fukano K, Tsukuda S, Oshima M, Suzuki R, Aizaki H, Ohki M, Park SY, Muramatsu M, Wakita T, Sureau C, Ogasawara Y, Watashi K.

Front Microbiol. 2019 Jan 8;9:3257. doi: 10.3389/fmicb.2018.03257. eCollection 2018.

10.

A Single Adaptive Mutation in Sodium Taurocholate Cotransporting Polypeptide Induced by Hepadnaviruses Determines Virus Species Specificity.

Takeuchi JS, Fukano K, Iwamoto M, Tsukuda S, Suzuki R, Aizaki H, Muramatsu M, Wakita T, Sureau C, Watashi K.

J Virol. 2019 Feb 19;93(5). pii: e01432-18. doi: 10.1128/JVI.01432-18. Print 2019 Mar 1.

11.

High-throughput neutralization assay for multiple flaviviruses based on single-round infectious particles using dengue virus type 1 reporter replicon.

Matsuda M, Yamanaka A, Yato K, Yoshii K, Watashi K, Aizaki H, Konishi E, Takasaki T, Kato T, Muramatsu M, Wakita T, Suzuki R.

Sci Rep. 2018 Nov 9;8(1):16624. doi: 10.1038/s41598-018-34865-y.

12.

The aryl hydrocarbon receptor-cytochrome P450 1A1 pathway controls lipid accumulation and enhances the permissiveness for hepatitis C virus assembly.

Ohashi H, Nishioka K, Nakajima S, Kim S, Suzuki R, Aizaki H, Fukasawa M, Kamisuki S, Sugawara F, Ohtani N, Muramatsu M, Wakita T, Watashi K.

J Biol Chem. 2018 Dec 21;293(51):19559-19571. doi: 10.1074/jbc.RA118.005033. Epub 2018 Oct 31.

13.

Thermostable hepatitis C virus JFH1-derived variant isolated by adaptation to Huh7.5.1 cells.

Shirasago Y, Fukazawa H, Aizaki H, Suzuki T, Suzuki T, Sugiyama K, Wakita T, Hanada K, Abe R, Fukasawa M.

J Gen Virol. 2018 Oct;99(10):1407-1417. doi: 10.1099/jgv.0.001117. Epub 2018 Jul 27.

PMID:
30045785
14.

A new strategy to identify hepatitis B virus entry inhibitors by AlphaScreen technology targeting the envelope-receptor interaction.

Saso W, Tsukuda S, Ohashi H, Fukano K, Morishita R, Matsunaga S, Ohki M, Ryo A, Park SY, Suzuki R, Aizaki H, Muramatsu M, Sureau C, Wakita T, Matano T, Watashi K.

Biochem Biophys Res Commun. 2018 Jun 22;501(2):374-379. doi: 10.1016/j.bbrc.2018.04.187. Epub 2018 May 11.

PMID:
29730285
15.

Chemical array system, a platform to identify novel hepatitis B virus entry inhibitors targeting sodium taurocholate cotransporting polypeptide.

Kaneko M, Futamura Y, Tsukuda S, Kondoh Y, Sekine T, Hirano H, Fukano K, Ohashi H, Saso W, Morishita R, Matsunaga S, Kawai F, Ryo A, Park SY, Suzuki R, Aizaki H, Ohtani N, Sureau C, Wakita T, Osada H, Watashi K.

Sci Rep. 2018 Feb 9;8(1):2769. doi: 10.1038/s41598-018-20987-w.

16.

Functional association of cellular microtubules with viral capsid assembly supports efficient hepatitis B virus replication.

Iwamoto M, Cai D, Sugiyama M, Suzuki R, Aizaki H, Ryo A, Ohtani N, Tanaka Y, Mizokami M, Wakita T, Guo H, Watashi K.

Sci Rep. 2017 Sep 6;7(1):10620. doi: 10.1038/s41598-017-11015-4.

17.

Nonstructural 5A Protein of Hepatitis C Virus Interferes with Toll-Like Receptor Signaling and Suppresses the Interferon Response in Mouse Liver.

Tsutsumi T, Okushin K, Enooku K, Fujinaga H, Moriya K, Yotsuyanagi H, Aizaki H, Suzuki T, Matsuura Y, Koike K.

PLoS One. 2017 Jan 20;12(1):e0170461. doi: 10.1371/journal.pone.0170461. eCollection 2017.

18.

A new class of hepatitis B and D virus entry inhibitors, proanthocyanidin and its analogs, that directly act on the viral large surface proteins.

Tsukuda S, Watashi K, Hojima T, Isogawa M, Iwamoto M, Omagari K, Suzuki R, Aizaki H, Kojima S, Sugiyama M, Saito A, Tanaka Y, Mizokami M, Sureau C, Wakita T.

Hepatology. 2017 Apr;65(4):1104-1116. doi: 10.1002/hep.28952. Epub 2017 Jan 17.

PMID:
27863453
19.

Fungus-Derived Neoechinulin B as a Novel Antagonist of Liver X Receptor, Identified by Chemical Genetics Using a Hepatitis C Virus Cell Culture System.

Nakajima S, Watashi K, Ohashi H, Kamisuki S, Izaguirre-Carbonell J, Kwon AT, Suzuki H, Kataoka M, Tsukuda S, Okada M, Moi ML, Takeuchi T, Arita M, Suzuki R, Aizaki H, Kato T, Suzuki T, Hasegawa H, Takasaki T, Sugawara F, Wakita T.

J Virol. 2016 Sep 29;90(20):9058-74. doi: 10.1128/JVI.00856-16. Print 2016 Oct 15.

20.

Human Cathelicidin Compensates for the Role of Apolipoproteins in Hepatitis C Virus Infectious Particle Formation.

Puig-Basagoiti F, Fukuhara T, Tamura T, Ono C, Uemura K, Kawachi Y, Yamamoto S, Mori H, Kurihara T, Okamoto T, Aizaki H, Matsuura Y.

J Virol. 2016 Sep 12;90(19):8464-77. doi: 10.1128/JVI.00471-16. Print 2016 Oct 1.

21.

Bivalent vaccine platform based on Japanese encephalitis virus (JEV) elicits neutralizing antibodies against JEV and hepatitis C virus.

Saga R, Fujimoto A, Watanabe N, Matsuda M, Hasegawa M, Watashi K, Aizaki H, Nakamura N, Tajima S, Takasaki T, Konishi E, Kato T, Kohara M, Takeyama H, Wakita T, Suzuki R.

Sci Rep. 2016 Jun 27;6:28688. doi: 10.1038/srep28688.

22.

Single-domain intrabodies against hepatitis C virus core inhibit viral propagation and core-induced NFκB activation.

Suzuki R, Saito K, Matsuda M, Sato M, Kanegae Y, Shi G, Watashi K, Aizaki H, Chiba J, Saito I, Wakita T, Suzuki T.

J Gen Virol. 2016 Apr;97(4):887-892. doi: 10.1099/jgv.0.000423. Epub 2016 Feb 9.

PMID:
26861864
23.

[Hepatitis C virus infection, its burden and countermeasures from the epidemiological point of view].

Tanaka J, Aizaki H, Uchida S.

Nihon Rinsho. 2015 Dec;73 Suppl 9:89-97. Japanese. No abstract available.

PMID:
26845910
24.

Prolactin Regulatory Element Binding Protein Is Involved in Hepatitis C Virus Replication by Interaction with NS4B.

Kong L, Fujimoto A, Nakamura M, Aoyagi H, Matsuda M, Watashi K, Suzuki R, Arita M, Yamagoe S, Dohmae N, Suzuki T, Sakamaki Y, Ichinose S, Suzuki T, Wakita T, Aizaki H.

J Virol. 2016 Jan 6;90(6):3093-111. doi: 10.1128/JVI.01540-15.

25.

A Novel Tricyclic Polyketide, Vanitaracin A, Specifically Inhibits the Entry of Hepatitis B and D Viruses by Targeting Sodium Taurocholate Cotransporting Polypeptide.

Kaneko M, Watashi K, Kamisuki S, Matsunaga H, Iwamoto M, Kawai F, Ohashi H, Tsukuda S, Shimura S, Suzuki R, Aizaki H, Sugiyama M, Park SY, Ito T, Ohtani N, Sugawara F, Tanaka Y, Mizokami M, Sureau C, Wakita T.

J Virol. 2015 Dec;89(23):11945-53. doi: 10.1128/JVI.01855-15. Epub 2015 Sep 16.

26.

Dysregulation of retinoic acid receptor diminishes hepatocyte permissiveness to hepatitis B virus infection through modulation of sodium taurocholate cotransporting polypeptide (NTCP) expression.

Tsukuda S, Watashi K, Iwamoto M, Suzuki R, Aizaki H, Okada M, Sugiyama M, Kojima S, Tanaka Y, Mizokami M, Li J, Tong S, Wakita T.

J Biol Chem. 2015 Feb 27;290(9):5673-84. doi: 10.1074/jbc.M114.602540. Epub 2014 Dec 30.

27.

Targeting cellular squalene synthase, an enzyme essential for cholesterol biosynthesis, is a potential antiviral strategy against hepatitis C virus.

Saito K, Shirasago Y, Suzuki T, Aizaki H, Hanada K, Wakita T, Nishijima M, Fukasawa M.

J Virol. 2015 Feb;89(4):2220-32. doi: 10.1128/JVI.03385-14. Epub 2014 Dec 3.

28.

Alternative endocytosis pathway for productive entry of hepatitis C virus.

Matsuda M, Suzuki R, Kataoka C, Watashi K, Aizaki H, Kato N, Matsuura Y, Suzuki T, Wakita T.

J Gen Virol. 2014 Dec;95(Pt 12):2658-2667. doi: 10.1099/vir.0.068528-0. Epub 2014 Aug 5.

PMID:
25096815
29.

Japanese consumers' valuation of domestic beef after the Fukushima Daiichi Nuclear Power Plant accident.

Sawada M, Aizaki H, Sato K.

Appetite. 2014 Sep;80:225-35. doi: 10.1016/j.appet.2014.05.018. Epub 2014 May 21.

PMID:
24859113
30.

Involvement of MAP3K8 and miR-17-5p in poor virologic response to interferon-based combination therapy for chronic hepatitis C.

Tsubota A, Mogushi K, Aizaki H, Miyaguchi K, Nagatsuma K, Matsudaira H, Kushida T, Furihata T, Tanaka H, Matsuura T.

PLoS One. 2014 May 12;9(5):e97078. doi: 10.1371/journal.pone.0097078. eCollection 2014.

31.

Development of hepatitis C virus genotype 3a cell culture system.

Kim S, Date T, Yokokawa H, Kono T, Aizaki H, Maurel P, Gondeau C, Wakita T.

Hepatology. 2014 Dec;60(6):1838-50. doi: 10.1002/hep.27197. Epub 2014 Jul 14.

PMID:
24797787
32.

Evaluation and identification of hepatitis B virus entry inhibitors using HepG2 cells overexpressing a membrane transporter NTCP.

Iwamoto M, Watashi K, Tsukuda S, Aly HH, Fukasawa M, Fujimoto A, Suzuki R, Aizaki H, Ito T, Koiwai O, Kusuhara H, Wakita T.

Biochem Biophys Res Commun. 2014 Jan 17;443(3):808-13. doi: 10.1016/j.bbrc.2013.12.052. Epub 2013 Dec 14.

33.

HCV NS3 protease enhances liver fibrosis via binding to and activating TGF-β type I receptor.

Sakata K, Hara M, Terada T, Watanabe N, Takaya D, Yaguchi S, Matsumoto T, Matsuura T, Shirouzu M, Yokoyama S, Yamaguchi T, Miyazawa K, Aizaki H, Suzuki T, Wakita T, Imoto M, Kojima S.

Sci Rep. 2013 Nov 22;3:3243. doi: 10.1038/srep03243.

34.

Specific inhibition of hepatitis C virus entry into host hepatocytes by fungi-derived sulochrin and its derivatives.

Nakajima S, Watashi K, Kamisuki S, Tsukuda S, Takemoto K, Matsuda M, Suzuki R, Aizaki H, Sugawara F, Wakita T.

Biochem Biophys Res Commun. 2013 Nov 1;440(4):515-20. doi: 10.1016/j.bbrc.2013.09.100. Epub 2013 Oct 5.

PMID:
24099774
35.

Production of single-round infectious chimeric flaviviruses with DNA-based Japanese encephalitis virus replicon.

Suzuki R, Ishikawa T, Konishi E, Matsuda M, Watashi K, Aizaki H, Takasaki T, Wakita T.

J Gen Virol. 2014 Jan;95(Pt 1):60-65. doi: 10.1099/vir.0.058008-0. Epub 2013 Oct 4.

PMID:
24096319
36.

Interleukin-1 and tumor necrosis factor-α trigger restriction of hepatitis B virus infection via a cytidine deaminase activation-induced cytidine deaminase (AID).

Watashi K, Liang G, Iwamoto M, Marusawa H, Uchida N, Daito T, Kitamura K, Muramatsu M, Ohashi H, Kiyohara T, Suzuki R, Li J, Tong S, Tanaka Y, Murata K, Aizaki H, Wakita T.

J Biol Chem. 2013 Nov 1;288(44):31715-27. doi: 10.1074/jbc.M113.501122. Epub 2013 Sep 11.

37.

Signal peptidase complex subunit 1 participates in the assembly of hepatitis C virus through an interaction with E2 and NS2.

Suzuki R, Matsuda M, Watashi K, Aizaki H, Matsuura Y, Wakita T, Suzuki T.

PLoS Pathog. 2013;9(8):e1003589. doi: 10.1371/journal.ppat.1003589. Epub 2013 Aug 29.

38.

Antiviral activity of glycyrrhizin against hepatitis C virus in vitro.

Matsumoto Y, Matsuura T, Aoyagi H, Matsuda M, Hmwe SS, Date T, Watanabe N, Watashi K, Suzuki R, Ichinose S, Wake K, Suzuki T, Miyamura T, Wakita T, Aizaki H.

PLoS One. 2013 Jul 18;8(7):e68992. doi: 10.1371/journal.pone.0068992. Print 2013.

39.

Neutralizing antibodies induced by cell culture-derived hepatitis C virus protect against infection in mice.

Akazawa D, Moriyama M, Yokokawa H, Omi N, Watanabe N, Date T, Morikawa K, Aizaki H, Ishii K, Kato T, Mochizuki H, Nakamura N, Wakita T.

Gastroenterology. 2013 Aug;145(2):447-55.e1-4. doi: 10.1053/j.gastro.2013.05.007. Epub 2013 May 11.

PMID:
23673355
40.

Japanese consumer preferences for milk certified with the good agricultural practice(GAP) label.

Aizaki H, Nanseki T, Zhou H.

Anim Sci J. 2013 Jan;84(1):82-9. doi: 10.1111/j.1740-0929.2012.01043.x. Epub 2012 Jul 9.

PMID:
23302087
41.

Hepatitis C virus translation preferentially depends on active RNA replication.

Liu HM, Aizaki H, Machida K, Ou JH, Lai MM.

PLoS One. 2012;7(8):e43600. doi: 10.1371/journal.pone.0043600. Epub 2012 Aug 24.

42.

Trans-complemented hepatitis C virus particles as a versatile tool for study of virus assembly and infection.

Suzuki R, Saito K, Kato T, Shirakura M, Akazawa D, Ishii K, Aizaki H, Kanegae Y, Matsuura Y, Saito I, Wakita T, Suzuki T.

Virology. 2012 Oct 10;432(1):29-38. doi: 10.1016/j.virol.2012.05.033. Epub 2012 Jun 22.

43.

Japanese reference panel of blood specimens for evaluation of hepatitis C virus RNA and core antigen quantitative assays.

Murayama A, Sugiyama N, Watashi K, Masaki T, Suzuki R, Aizaki H, Mizuochi T, Wakita T, Kato T.

J Clin Microbiol. 2012 Jun;50(6):1943-9. doi: 10.1128/JCM.00487-12. Epub 2012 Apr 11.

44.

Visualization and measurement of ATP levels in living cells replicating hepatitis C virus genome RNA.

Ando T, Imamura H, Suzuki R, Aizaki H, Watanabe T, Wakita T, Suzuki T.

PLoS Pathog. 2012;8(3):e1002561. doi: 10.1371/journal.ppat.1002561. Epub 2012 Mar 1.

45.

[Critical roles of lipids in the HCV life cycle].

Aizaki H, Suzuki T, Wakita T.

Nihon Rinsho. 2011 May;69 Suppl 4:59-63. Review. Japanese. No abstract available.

PMID:
22096894
46.

Consumers' attitudes toward consumption of cloned beef. The impact of exposure to technological information about animal cloning.

Aizaki H, Sawada M, Sato K.

Appetite. 2011 Oct;57(2):459-66. doi: 10.1016/j.appet.2011.06.011. Epub 2011 Jun 24.

PMID:
21723894
47.

Structural requirements of virion-associated cholesterol for infectivity, buoyant density and apolipoprotein association of hepatitis C virus.

Yamamoto M, Aizaki H, Fukasawa M, Teraoka T, Miyamura T, Wakita T, Suzuki T.

J Gen Virol. 2011 Sep;92(Pt 9):2082-2087. doi: 10.1099/vir.0.032391-0. Epub 2011 May 18.

PMID:
21593275
48.

Hepatitis C virus RNA replication in human stellate cells regulates gene expression of extracellular matrix-related molecules.

Watanabe N, Aizaki H, Matsuura T, Kojima S, Wakita T, Suzuki T.

Biochem Biophys Res Commun. 2011 Apr 1;407(1):135-40. doi: 10.1016/j.bbrc.2011.02.125. Epub 2011 Mar 1.

PMID:
21371436
49.

Impressions and purchasing intentions of Japanese consumers regarding pork produced by 'Ecofeed,' a trademark of food-waste or food co-product animal feed certified by the Japanese government.

Sasaki K, Aizaki H, Motoyama M, Ohmori H, Kawashima T.

Anim Sci J. 2011 Feb;82(1):175-80. doi: 10.1111/j.1740-0929.2010.00817.x. Epub 2010 Oct 29.

PMID:
21269377
50.

Chaperonin TRiC/CCT participates in replication of hepatitis C virus genome via interaction with the viral NS5B protein.

Inoue Y, Aizaki H, Hara H, Matsuda M, Ando T, Shimoji T, Murakami K, Masaki T, Shoji I, Homma S, Matsuura Y, Miyamura T, Wakita T, Suzuki T.

Virology. 2011 Feb 5;410(1):38-47. doi: 10.1016/j.virol.2010.10.026. Epub 2010 Nov 18.

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