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Items: 1 to 50 of 84

1.

Antibody response to the 23-valent pneumococcal polysaccharide vaccine after conjugate vaccine in patients with chronic lymphocytic leukemia.

Lindström V, Aittoniemi J, Salmenniemi U, Käyhty H, Huhtala H, Sinisalo M.

Hum Vaccin Immunother. 2019 Jun 19. doi: 10.1080/21645515.2019.1627160. [Epub ahead of print]

PMID:
31216225
2.

Reduced plasma PCSK9 response in patients with bacteraemia is associated with mortality.

Rannikko J, Jacome Sanz D, Ortutay Z, Seiskari T, Aittoniemi J, Huttunen R, Syrjänen J, Pesu M.

J Intern Med. 2019 Jun 5. doi: 10.1111/joim.12946. [Epub ahead of print]

PMID:
31166632
3.

Chlamydia trachomatis samples testing falsely negative in the Aptima Combo 2 test in Finland, 2019.

Rantakokko-Jalava K, Hokynar K, Hieta N, Keskitalo A, Jokela P, Muotiala A, Jokiranta TS, Kuusela R, Sarkkinen H, Aittoniemi J, Vuorinen T, Hakanen AJ, Puolakkainen M.

Euro Surveill. 2019 May;24(22). doi: 10.2807/1560-7917.ES.2019.24.22.1900298.

4.

Plasma level of soluble urokinase plasminogen activator receptor (suPAR) predicts long-term mortality after first acute alcohol-induced pancreatitis.

Aronen A, Aittoniemi J, Huttunen R, Nikkola A, Nikkola J, Limnell O, Nordback I, Sand J, Laukkarinen J.

Eur J Intern Med. 2019 Jun;64:72-75. doi: 10.1016/j.ejim.2019.04.007. Epub 2019 May 3.

PMID:
31060962
5.

Pregestational overweight and obesity are associated with differences in gut microbiota composition and systemic inflammation in the third trimester.

Zacarías MF, Collado MC, Gómez-Gallego C, Flinck H, Aittoniemi J, Isolauri E, Salminen S.

PLoS One. 2018 Jul 13;13(7):e0200305. doi: 10.1371/journal.pone.0200305. eCollection 2018.

6.

Plasma cell-free DNA and qSOFA score predict 7-day mortality in 481 emergency department bacteraemia patients.

Rannikko J, Seiskari T, Huttunen R, Tarkiainen I, Jylhävä J, Hurme M, Syrjänen J, Aittoniemi J.

J Intern Med. 2018 Oct;284(4):418-426. doi: 10.1111/joim.12766. Epub 2018 Jun 3.

PMID:
29687943
7.

Antibody persistence after pneumococcal conjugate vaccination in patients with chronic lymphocytic leukemia.

Lindström V, Aittoniemi J, Salmenniemi U, Käyhty H, Huhtala H, Itälä-Remes M, Sinisalo M.

Hum Vaccin Immunother. 2018 Jun 3;14(6):1471-1474. doi: 10.1080/21645515.2018.1436424. Epub 2018 Feb 23.

8.

Electronic Nose in the Detection of Wound Infection Bacteria from Bacterial Cultures: A Proof-of-Principle Study.

Saviauk T, Kiiski JP, Nieminen MK, Tamminen NN, Roine AN, Kumpulainen PS, Hokkinen LJ, Karjalainen MT, Vuento RE, Aittoniemi JJ, Lehtimäki TJ, Oksala NK.

Eur Surg Res. 2018;59(1-2):1-11. doi: 10.1159/000485461. Epub 2018 Jan 10.

PMID:
29320769
9.

A Serratia marcescens outbreak in a neonatal intensive care unit was successfully managed by rapid hospital hygiene interventions and screening.

Åttman E, Korhonen P, Tammela O, Vuento R, Aittoniemi J, Syrjänen J, Mattila E, Österblad M, Huttunen R.

Acta Paediatr. 2018 Mar;107(3):425-429. doi: 10.1111/apa.14132. Epub 2017 Nov 21.

PMID:
29068091
10.

Bloodstream infections in acute myeloid leukemia patients treated according to the Finnish Leukemia Group AML-2003 protocol - a prospective nationwide study.

Kolonen A, Sinisalo M, Huttunen R, Syrjänen J, Aittoniemi J, Huhtala H, Sankelo M, Rintala H, Räty R, Jantunen E, Nousiainen T, Säily M, Kauppila M, Itälä-Remes M, Ollikainen H, Rauhala A, Koistinen P, Elonen E; Finnish Leukemia Group.

Infect Dis (Lond). 2017 Nov - Dec;49(11-12):799-808. doi: 10.1080/23744235.2017.1347814. Epub 2017 Jul 6.

PMID:
28683646
11.

Next-Generation Sequencing Combined with Specific PCR Assays To Determine the Bacterial 16S rRNA Gene Profiles of Middle Ear Fluid Collected from Children with Acute Otitis Media.

Sillanpää S, Kramna L, Oikarinen S, Sipilä M, Rautiainen M, Aittoniemi J, Laranne J, Hyöty H, Cinek O.

mSphere. 2017 Mar 22;2(2). pii: e00006-17. doi: 10.1128/mSphere.00006-17. eCollection 2017 Mar-Apr.

12.

Sepsis-related mortality in 497 cases with blood culture-positive sepsis in an emergency department.

Rannikko J, Syrjänen J, Seiskari T, Aittoniemi J, Huttunen R.

Int J Infect Dis. 2017 May;58:52-57. doi: 10.1016/j.ijid.2017.03.005. Epub 2017 Mar 10.

13.

Plasma Level of Soluble Urokinase-type Plasminogen Activator Receptor Predicts the Severity of Acute Alcohol Pancreatitis.

Nikkola A, Aittoniemi J, Huttunen R, Rajala L, Nordback I, Sand J, Laukkarinen J.

Pancreas. 2017 Jan;46(1):77-82.

PMID:
27841794
14.

Moraxella catarrhalis Might Be More Common than Expected in Acute Otitis Media in Young Finnish Children.

Sillanpää S, Oikarinen S, Sipilä M, Kramna L, Rautiainen M, Huhtala H, Aittoniemi J, Laranne J, Hyöty H, Cinek O.

J Clin Microbiol. 2016 Sep;54(9):2373-9. doi: 10.1128/JCM.01146-16. Epub 2016 Jul 13.

15.

Invasive pneumococcal disease in patients with haematological malignancies before routine use of conjugate vaccines in Finland.

Lindström V, Aittoniemi J, Lyytikäinen O, Klemets P, Ollgren J, Silvennoinen R, Nuorti JP, Sinisalo M.

Infect Dis (Lond). 2016;48(5):399-402. doi: 10.3109/23744235.2015.1115894. Epub 2015 Dec 4.

PMID:
26635103
16.

The Plasma Level of Proprotein Convertase FURIN in Patients with Suspected Infection in the Emergency Room: A Prospective Cohort Study.

Ranta N, Turpeinen H, Oksanen A, Hämäläinen S, Huttunen R, Uusitalo-Seppälä R, Rintala E, Aittoniemi J, Pesu M.

Scand J Immunol. 2015 Dec;82(6):539-46. doi: 10.1111/sji.12386.

17.

Finnish guidelines for the treatment of community-acquired pneumonia and pertussis in children.

Tapiainen T, Aittoniemi J, Immonen J, Jylkkä H, Meinander T, Nuolivirta K, Peltola V, Salo E, Seuri R, Walle SM, Korppi M.

Acta Paediatr. 2016 Jan;105(1):39-43. doi: 10.1111/apa.13177. Epub 2015 Nov 16.

PMID:
26341383
18.

Finnish guidelines for the treatment of laryngitis, wheezing bronchitis and bronchiolitis in children.

Tapiainen T, Aittoniemi J, Immonen J, Jylkkä H, Meinander T, Nuolivirta K, Peltola V, Salo E, Seuri R, Walle SM, Korppi M.

Acta Paediatr. 2016 Jan;105(1):44-9. doi: 10.1111/apa.13162. Epub 2015 Nov 6.

PMID:
26295564
19.

Use of an automated PCR assay, the GenomEra S. pneumoniae, for rapid detection of Streptococcus pneumoniae in blood cultures.

Hirvonen JJ, Seiskari T, Harju I, Rantakokko-Jalava K, Vuento R, Aittoniemi J.

Infect Dis (Lond). 2015;47(11):796-800. doi: 10.3109/23744235.2015.1063157. Epub 2015 Jul 10.

PMID:
26162002
20.

Etiology, clinical course and outcome of healthcare-associated bloodstream infections in patients with hematological malignancies: a retrospective study of 350 patients in a Finnish tertiary care hospital.

Åttman E, Aittoniemi J, Sinisalo M, Vuento R, Lyytikäinen O, Kärki T, Syrjänen J, Huttunen R.

Leuk Lymphoma. 2015;56(12):3370-7. doi: 10.3109/10428194.2015.1032967. Epub 2015 Oct 5.

PMID:
25813080
21.

Rapid and accurate detection of urinary pathogens by mobile IMS-based electronic nose: a proof-of-principle study.

Roine A, Saviauk T, Kumpulainen P, Karjalainen M, Tuokko A, Aittoniemi J, Vuento R, Lekkala J, Lehtimäki T, Tammela TL, Oksala NK.

PLoS One. 2014 Dec 19;9(12):e114279. doi: 10.1371/journal.pone.0114279. eCollection 2014.

22.

Predictors of recurrent cellulitis in five years. Clinical risk factors and the role of PTX3 and CRP.

Karppelin M, Siljander T, Aittoniemi J, Hurme M, Huttunen R, Huhtala H, Kere J, Vuopio J, Syrjänen J.

J Infect. 2015 May;70(5):467-73. doi: 10.1016/j.jinf.2014.11.002. Epub 2014 Nov 15.

PMID:
25447714
23.

Oral bacterial DNA findings in pericardial fluid.

Louhelainen AM, Aho J, Tuomisto S, Aittoniemi J, Vuento R, Karhunen PJ, Pessi T.

J Oral Microbiol. 2014 Nov 19;6:25835. doi: 10.3402/jom.v6.25835. eCollection 2014.

24.

Evidence of streptococcal origin of acute non-necrotising cellulitis: a serological study.

Karppelin M, Siljander T, Haapala AM, Aittoniemi J, Huttunen R, Kere J, Vuopio J, Syrjänen J.

Eur J Clin Microbiol Infect Dis. 2015 Apr;34(4):669-72. doi: 10.1007/s10096-014-2274-9. Epub 2014 Nov 18.

PMID:
25403372
25.

Nosocomial bloodstream infections in a Finnish tertiary care hospital: a retrospective cohort study of 2175 episodes during the years 1999-2001 and 2005-2010.

Huttunen R, Åttman E, Aittoniemi J, Outinen T, Syrjänen J, Kärki T, Lyytikäinen O.

Infect Dis (Lond). 2015 Jan;47(1):20-6. doi: 10.3109/00365548.2014.956791. Epub 2014 Oct 29.

PMID:
25351869
26.

Urine soluble urokinase-type plasminogen activator receptor levels correlate with proteinuria in Puumala hantavirus infection.

Outinen TK, Mäkelä S, Huttunen R, Mäenpää N, Libraty D, Vaheri A, Mustonen J, Aittoniemi J.

J Intern Med. 2014 Oct;276(4):387-95. doi: 10.1111/joim.12257. Epub 2014 May 14.

27.

Changes in gut bacterial populations and their translocation into liver and ascites in alcoholic liver cirrhotics.

Tuomisto S, Pessi T, Collin P, Vuento R, Aittoniemi J, Karhunen PJ.

BMC Gastroenterol. 2014 Feb 24;14:40. doi: 10.1186/1471-230X-14-40.

28.

High cell-free DNA predicts fatal outcome among Staphylococcus aureus bacteraemia patients with intensive care unit treatment.

Forsblom E, Aittoniemi J, Ruotsalainen E, Helmijoki V, Huttunen R, Jylhävä J, Hurme M, Järvinen A.

PLoS One. 2014 Feb 10;9(2):e87741. doi: 10.1371/journal.pone.0087741. eCollection 2014.

29.

Isotropic bicelles stabilize the juxtamembrane region of the influenza M2 protein for solution NMR studies.

Claridge JK, Aittoniemi J, Cooper DM, Schnell JR.

Biochemistry. 2013 Nov 26;52(47):8420-9. doi: 10.1021/bi401035m. Epub 2013 Nov 14.

PMID:
24168642
30.

Plasma levels of soluble urokinase-type plasminogen activator receptor associate with the clinical severity of acute Puumala hantavirus infection.

Outinen TK, Tervo L, Mäkelä S, Huttunen R, Mäenpää N, Huhtala H, Vaheri A, Mustonen J, Aittoniemi J.

PLoS One. 2013 Aug 21;8(8):e71335. doi: 10.1371/journal.pone.0071335. eCollection 2013.

31.

Current concepts in the diagnosis of blood stream infections. Are novel molecular methods useful in clinical practice?

Huttunen R, Syrjänen J, Vuento R, Aittoniemi J.

Int J Infect Dis. 2013 Nov;17(11):e934-8. doi: 10.1016/j.ijid.2013.04.018. Epub 2013 Jul 16. Review.

32.

Evaluation of postmortem bacterial migration using culturing and real-time quantitative PCR.

Tuomisto S, Karhunen PJ, Vuento R, Aittoniemi J, Pessi T.

J Forensic Sci. 2013 Jul;58(4):910-6. doi: 10.1111/1556-4029.12124. Epub 2013 Mar 29.

PMID:
23550887
33.

Pentraxin 3 (PTX3) is associated with severe sepsis and fatal disease in emergency room patients with suspected infection: a prospective cohort study.

Uusitalo-Seppälä R, Huttunen R, Aittoniemi J, Koskinen P, Leino A, Vahlberg T, Rintala EM.

PLoS One. 2013;8(1):e53661. doi: 10.1371/journal.pone.0053661. Epub 2013 Jan 14.

34.

Tetrameric structure of SUR2B revealed by electron microscopy of oriented single particles.

Fotinou C, Aittoniemi J, de Wet H, Polidori A, Pucci B, Sansom MS, Vénien-Bryan C, Ashcroft FM.

FEBS J. 2013 Feb;280(4):1051-63. doi: 10.1111/febs.12097. Epub 2013 Jan 27.

35.

Indoleamine 2,3-dioxygenase activity and expression in patients with chronic lymphocytic leukemia.

Lindström V, Aittoniemi J, Jylhävä J, Eklund C, Hurme M, Paavonen T, Oja SS, Itälä-Remes M, Sinisalo M.

Clin Lymphoma Myeloma Leuk. 2012 Oct;12(5):363-5. doi: 10.1016/j.clml.2012.06.001. Epub 2012 Sep 13.

PMID:
22981691
36.

A universally conserved residue in the SUR1 subunit of the KATP channel is essential for translating nucleotide binding at SUR1 into channel opening.

de Wet H, Shimomura K, Aittoniemi J, Ahmad N, Lafond M, Sansom MS, Ashcroft FM.

J Physiol. 2012 Oct 15;590(20):5025-36. doi: 10.1113/jphysiol.2012.236075. Epub 2012 Jul 16.

37.

Soluble urokinase-type plasminogen activator receptor in patients with suspected infection in the emergency room: a prospective cohort study.

Uusitalo-Seppälä R, Huttunen R, Tarkka M, Aittoniemi J, Koskinen P, Leino A, Vahlberg T, Rintala EM.

J Intern Med. 2012 Sep;272(3):247-56. doi: 10.1111/j.1365-2796.2012.02569.x. Epub 2012 Jul 29.

38.

Case fatality associated with a hypervirulent strain in patients with culture-positive Clostridium difficile infection: a retrospective population-based study.

Huttunen R, Vuento R, Syrjänen J, Tissari P, Aittoniemi J.

Int J Infect Dis. 2012 Jul;16(7):e532-5. doi: 10.1016/j.ijid.2012.02.019. Epub 2012 May 7.

39.

Risk factors for mortality in patients with Clostridium difficile infection.

Huttunen R, Aittoniemi J.

Clin Infect Dis. 2012 Apr;54(8):1214; author reply 1214-5. doi: 10.1093/cid/cis019. Epub 2012 Feb 21. No abstract available.

PMID:
22354921
40.

Relation of high cytomegalovirus antibody titres to blood pressure and brachial artery flow-mediated dilation in young men: the Cardiovascular Risk in Young Finns Study.

Haarala A, Kähönen M, Lehtimäki T, Aittoniemi J, Jylhävä J, Hutri-Kähönen N, Taittonen L, Laitinen T, Juonala M, Viikari J, Raitakari OT, Hurme M.

Clin Exp Immunol. 2012 Feb;167(2):309-16. doi: 10.1111/j.1365-2249.2011.04513.x.

41.

Apoptosis markers soluble Fas (sFas), Fas Ligand (FasL) and sFas/FasL ratio in patients with bacteremia: a prospective cohort study.

Huttunen R, Syrjänen J, Vuento R, Laine J, Hurme M, Aittoniemi J.

J Infect. 2012 Mar;64(3):276-81. doi: 10.1016/j.jinf.2011.12.006. Epub 2011 Dec 19.

PMID:
22207003
42.

Genome-wide association study does not reveal major genetic determinants for anti-cytomegalovirus antibody response.

Kuparinen T, Seppälä I, Jylhävä J, Marttila S, Aittoniemi J, Kettunen J, Viikari J, Kähönen M, Raitakari O, Lehtimäki T, Hurme M.

Genes Immun. 2012 Feb;13(2):184-90. doi: 10.1038/gene.2011.71. Epub 2011 Oct 13.

PMID:
21993531
43.

New concepts in the pathogenesis, diagnosis and treatment of bacteremia and sepsis.

Huttunen R, Aittoniemi J.

J Infect. 2011 Dec;63(6):407-19. doi: 10.1016/j.jinf.2011.08.004. Epub 2011 Aug 9. Review.

PMID:
21840338
44.

Fatal outcome in bacteremia is characterized by high plasma cell free DNA concentration and apoptotic DNA fragmentation: a prospective cohort study.

Huttunen R, Kuparinen T, Jylhävä J, Aittoniemi J, Vuento R, Huhtala H, Laine J, Syrjänen J, Hurme M.

PLoS One. 2011;6(7):e21700. doi: 10.1371/journal.pone.0021700. Epub 2011 Jul 1.

45.

High plasma level of long pentraxin 3 (PTX3) is associated with fatal disease in bacteremic patients: a prospective cohort study.

Huttunen R, Hurme M, Aittoniemi J, Huhtala H, Vuento R, Laine J, Jylhävä J, Syrjänen J.

PLoS One. 2011 Mar 10;6(3):e17653. doi: 10.1371/journal.pone.0017653.

46.

The value of HCV antigen test with reference to PCR in confirming infection in cases with indefinite antibody test result.

Seiskari T, Horsti J, Aittoniemi J.

J Clin Virol. 2011 May;51(1):90-1. doi: 10.1016/j.jcv.2011.02.003. Epub 2011 Mar 4. No abstract available.

PMID:
21377410
47.

Plasma level of soluble urokinase-type plasminogen activator receptor as a predictor of disease severity and case fatality in patients with bacteraemia: a prospective cohort study.

Huttunen R, Syrjänen J, Vuento R, Hurme M, Huhtala H, Laine J, Pessi T, Aittoniemi J.

J Intern Med. 2011 Jul;270(1):32-40. doi: 10.1111/j.1365-2796.2011.02363.x. Epub 2011 Mar 21.

48.

Asymmetric switching in a homodimeric ABC transporter: a simulation study.

Aittoniemi J, de Wet H, Ashcroft FM, Sansom MS.

PLoS Comput Biol. 2010 Apr 29;6(4):e1000762. doi: 10.1371/journal.pcbi.1000762.

49.

From Abbott ARCHITECT anti-HBc to Anti-HBc II--improved performance in detecting antibodies to hepatitis B core antigen.

Seiskari T, Lehtisaari H, Haapala AM, Aittoniemi J.

J Clin Virol. 2010 Jan;47(1):100-1. doi: 10.1016/j.jcv.2009.11.010. Epub 2009 Dec 3. No abstract available.

PMID:
19962345
50.

HLA-DRB1*01 allele and low plasma immunoglobulin G1 concentration may predispose to herpes-associated recurrent lymphocytic meningitis.

Kallio-Laine K, Seppänen M, Aittoniemi J, Kautiainen H, Seppälä I, Valtonen V, Färkkilä M, Kalso E, Lokki ML.

Hum Immunol. 2010 Feb;71(2):179-81. doi: 10.1016/j.humimm.2009.10.014. Epub 2009 Oct 30.

PMID:
19879913

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