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Items: 17


Genetic mutations associated with lung cancer metastasis to the brain.

Aljohani HM, Aittaleb M, Furgason JM, Amaya P, Deeb A, Chalmers JJ, Bahassi EM.

Mutagenesis. 2018 Apr 13;33(2):137-145. doi: 10.1093/mutage/gey003.


Spatial distribution and molecular dynamics of dystrophin glycoprotein components at the neuromuscular junction in vivo.

Aittaleb M, Martinez-Pena Y Valenzuela I, Akaaboune M.

J Cell Sci. 2017 May 15;130(10):1752-1759. doi: 10.1242/jcs.198358. Epub 2017 Mar 31.


AChRs Are Essential for the Targeting of Rapsyn to the Postsynaptic Membrane of NMJs in Living Mice.

Chen PJ, Martinez-Pena Y Valenzuela I, Aittaleb M, Akaaboune M.

J Neurosci. 2016 May 25;36(21):5680-5. doi: 10.1523/JNEUROSCI.4580-15.2016.


Failure of lysosome clustering and positioning in the juxtanuclear region in cells deficient in rapsyn.

Aittaleb M, Chen PJ, Akaaboune M.

J Cell Sci. 2015 Oct 15;128(20):3744-56. doi: 10.1242/jcs.172536. Epub 2015 Sep 1.


The knockdown of αkap alters the postsynaptic apparatus of neuromuscular junctions in living mice.

Martinez-Pena Y Valenzuela I, Aittaleb M, Chen PJ, Akaaboune M.

J Neurosci. 2015 Apr 1;35(13):5118-27. doi: 10.1523/JNEUROSCI.3951-14.2015.


A role for the calmodulin kinase II-related anchoring protein (αkap) in maintaining the stability of nicotinic acetylcholine receptors.

Mouslim C, Aittaleb M, Hume RI, Akaaboune M.

J Neurosci. 2012 Apr 11;32(15):5177-85. doi: 10.1523/JNEUROSCI.6477-11.2012.


Plasma membrane association of p63 Rho guanine nucleotide exchange factor (p63RhoGEF) is mediated by palmitoylation and is required for basal activity in cells.

Aittaleb M, Nishimura A, Linder ME, Tesmer JJ.

J Biol Chem. 2011 Sep 30;286(39):34448-56. doi: 10.1074/jbc.M111.273342. Epub 2011 Aug 10.


Galpha q allosterically activates and relieves autoinhibition of p63RhoGEF.

Shankaranarayanan A, Boguth CA, Lutz S, Vettel C, Uhlemann F, Aittaleb M, Wieland T, Tesmer JJ.

Cell Signal. 2010 Jul;22(7):1114-23. doi: 10.1016/j.cellsig.2010.03.006. Epub 2010 Mar 7.


Structure and function of heterotrimeric G protein-regulated Rho guanine nucleotide exchange factors.

Aittaleb M, Boguth CA, Tesmer JJ.

Mol Pharmacol. 2010 Feb;77(2):111-25. doi: 10.1124/mol.109.061234. Epub 2009 Oct 30. Review.


A conserved hydrophobic surface of the LARG pleckstrin homology domain is critical for RhoA activation in cells.

Aittaleb M, Gao G, Evelyn CR, Neubig RR, Tesmer JJ.

Cell Signal. 2009 Nov;21(11):1569-78. doi: 10.1016/j.cellsig.2009.06.003. Epub 2009 Jun 26.


Structural and thermodynamic evidence for a stabilizing role of Nop5p in S-adenosyl-L-methionine binding to fibrillarin.

Aittaleb M, Visone T, Fenley MO, Li H.

J Biol Chem. 2004 Oct 1;279(40):41822-9. Epub 2004 Jul 30.


Functional requirement for symmetric assembly of archaeal box C/D small ribonucleoprotein particles.

Rashid R, Aittaleb M, Chen Q, Spiegel K, Demeler B, Li H.

J Mol Biol. 2003 Oct 17;333(2):295-306. Erratum in: J Mol Biol. 2004 Sep 24;342(4):1347.


Structure and function of archaeal box C/D sRNP core proteins.

Aittaleb M, Rashid R, Chen Q, Palmer JR, Daniels CJ, Li H.

Nat Struct Biol. 2003 Apr;10(4):256-63.


Structural, kinetic, and calorimetric characterization of the cold-active phosphoglycerate kinase from the antarctic Pseudomonas sp. TACII18.

Bentahir M, Feller G, Aittaleb M, Lamotte-Brasseur J, Himri T, Chessa JP, Gerday C.

J Biol Chem. 2000 Apr 14;275(15):11147-53.


Cold-adapted enzymes: from fundamentals to biotechnology.

Gerday C, Aittaleb M, Bentahir M, Chessa JP, Claverie P, Collins T, D'Amico S, Dumont J, Garsoux G, Georlette D, Hoyoux A, Lonhienne T, Meuwis MA, Feller G.

Trends Biotechnol. 2000 Mar;18(3):103-7. Review.


Psychrophilic enzymes: a thermodynamic challenge.

Gerday C, Aittaleb M, Arpigny JL, Baise E, Chessa JP, Garsoux G, Petrescu I, Feller G.

Biochim Biophys Acta. 1997 Oct 17;1342(2):119-31. Review.


Cold adaptation parameters derived from cDNA sequencing and molecular modelling of elastase from Antarctic fish Notothenia neglecta.

Aittaleb M, Hubner R, Lamotte-Brasseur J, Gerday C.

Protein Eng. 1997 May;10(5):475-7.


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