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Strong toll-like receptor responses in cystic fibrosis patients are associated with higher lung function.

Kosamo S, Hisert KB, Dmyterko V, Nguyen C, Black RA, Holden TD, Radella F, Cotten PA, Goss CH, Aitken ML, Wurfel MM.

J Cyst Fibros. 2019 Dec 5. pii: S1569-1993(19)30973-7. doi: 10.1016/j.jcf.2019.11.009. [Epub ahead of print]


The expanding phenotype of OFD1-related disorders: Hemizygous loss-of-function variants in three patients with primary ciliary dyskinesia.

Hannah WB, DeBrosse S, Kinghorn B, Strausbaugh S, Aitken ML, Rosenfeld M, Wolf WE, Knowles MR, Zariwala MA.

Mol Genet Genomic Med. 2019 Sep;7(9):e911. doi: 10.1002/mgg3.911. Epub 2019 Aug 1.


A Survey Identifying Nutritional Needs in a Contemporary Adult Cystic Fibrosis Cohort.

Kapnadak SG, Ramos KJ, Lopriore AM, Goss CH, Aitken ML.

BMC Nutr. 2019;5. pii: 4. doi: 10.1186/s40795-018-0266-3. Epub 2019 Jan 7.


Addressing lung transplant with adults with cystic fibrosis: A qualitative analysis of patients' perspectives and experiences.

Ramos KJ, Hobler MR, Engelberg RA, Curtis JR, Zander MI, Howard SS, Goss CH, Aitken ML.

J Cyst Fibros. 2019 May;18(3):416-419. doi: 10.1016/j.jcf.2019.04.007. Epub 2019 Apr 17.


Higher Plasma Endothelial Markers in Adults with Cystic Fibrosis Compared with Healthy Age-matched Control Subjects.

Bhatraju PK, Hisert KB, Aitken ML, Goss CH, Liles WC, Altemeier WA.

Ann Am Thorac Soc. 2019 Jun;16(6):768-771. doi: 10.1513/AnnalsATS.201812-844RL. No abstract available.


Transcriptional and functional diversity of human macrophage repolarization.

Gharib SA, McMahan RS, Eddy WE, Long ME, Parks WC, Aitken ML, Manicone AM.

J Allergy Clin Immunol. 2019 Apr;143(4):1536-1548. doi: 10.1016/j.jaci.2018.10.046. Epub 2018 Nov 14.


Gallium disrupts bacterial iron metabolism and has therapeutic effects in mice and humans with lung infections.

Goss CH, Kaneko Y, Khuu L, Anderson GD, Ravishankar S, Aitken ML, Lechtzin N, Zhou G, Czyz DM, McLean K, Olakanmi O, Shuman HA, Teresi M, Wilhelm E, Caldwell E, Salipante SJ, Hornick DB, Siehnel RJ, Becker L, Britigan BE, Singh PK.

Sci Transl Med. 2018 Sep 26;10(460). pii: eaat7520. doi: 10.1126/scitranslmed.aat7520.


Changing Rates of Chronic Pseudomonas aeruginosa Infections in Cystic Fibrosis: A Population-Based Cohort Study.

Crull MR, Somayaji R, Ramos KJ, Caldwell E, Mayer-Hamblett N, Aitken ML, Nichols DP, Rowhani-Rahbar A, Goss CH.

Clin Infect Dis. 2018 Sep 14;67(7):1089-1095. doi: 10.1093/cid/ciy215.


Exploring Opportunities for Primary Outpatient Palliative Care for Adults with Cystic Fibrosis: A Mixed-Methods Study of Patients' Needs.

Hobler MR, Engelberg RA, Curtis JR, Ramos KJ, Zander MI, Howard SS, Goss CH, Aitken ML.

J Palliat Med. 2018 Apr;21(4):513-521. doi: 10.1089/jpm.2017.0259. Epub 2018 Jan 3.


Tracheal diverticula in advanced cystic fibrosis: Prevalence, features, and outcomes after lung transplantation.

Kapnadak SG, Kicska GA, Ramos KJ, Marshall DA, Carroll TY, Pipavath SN, Mulligan MS, Goss CH, Aitken ML.

J Cyst Fibros. 2017 Nov;16(6):735-743. doi: 10.1016/j.jcf.2017.07.015. Epub 2017 Jul 28.


Gender Equality in Academic Medicine Requires Changes for Both Men and Women.

Adamson R, Brady AK, Aitken ML.

Acad Med. 2017 Aug;92(8):1067. doi: 10.1097/ACM.0000000000001791. No abstract available.


Home Monitoring of Patients with Cystic Fibrosis to Identify and Treat Acute Pulmonary Exacerbations. eICE Study Results.

Lechtzin N, Mayer-Hamblett N, West NE, Allgood S, Wilhelm E, Khan U, Aitken ML, Ramsey BW, Boyle MP, Mogayzel PJ Jr, Gibson RL, Orenstein D, Milla C, Clancy JP, Antony V, Goss CH; eICE Study Team.

Am J Respir Crit Care Med. 2017 Nov 1;196(9):1144-1151. doi: 10.1164/rccm.201610-2172OC.


Common clinical features of CF (respiratory disease and exocrine pancreatic insufficiency).

Somayaji R, Ramos KJ, Kapnadak SG, Aitken ML, Goss CH.

Presse Med. 2017 Jun;46(6 Pt 2):e109-e124. doi: 10.1016/j.lpm.2017.03.021. Epub 2017 May 26. Review.


Pregnancy among cystic fibrosis women in the era of CFTR modulators.

Heltshe SL, Godfrey EM, Josephy T, Aitken ML, Taylor-Cousar JL.

J Cyst Fibros. 2017 Nov;16(6):687-694. doi: 10.1016/j.jcf.2017.01.008. Epub 2017 Feb 10.


Heterogeneity in Survival in Adult Patients With Cystic Fibrosis With FEV1 < 30% of Predicted in the United States.

Ramos KJ, Quon BS, Heltshe SL, Mayer-Hamblett N, Lease ED, Aitken ML, Weiss NS, Goss CH.

Chest. 2017 Jun;151(6):1320-1328. doi: 10.1016/j.chest.2017.01.019. Epub 2017 Jan 20.


Cystic fibrosis physicians' perspectives on the timing of referral for lung transplant evaluation: a survey of physicians in the United States.

Ramos KJ, Somayaji R, Lease ED, Goss CH, Aitken ML.

BMC Pulm Med. 2017 Jan 19;17(1):21. doi: 10.1186/s12890-017-0367-9.


Change in Pseudomonas aeruginosa prevalence in cystic fibrosis adults over time.

Crull MR, Ramos KJ, Caldwell E, Mayer-Hamblett N, Aitken ML, Goss CH.

BMC Pulm Med. 2016 Dec 7;16(1):176.


Deaths Related to Bronchial Arterial Embolization in Patients With Cystic Fibrosis: Three Cases and an Institutional Review.

Town JA, Monroe EJ, Aitken ML.

Chest. 2016 Oct;150(4):e93-e98. doi: 10.1016/j.chest.2016.03.009. Erratum in: Chest. 2019 Jan;155(1):246.


Approach to the evaluation of adverse antibiotic reactions in patients with cystic fibrosis.

Petroni DH, Aitken ML, Ham E, Chung S, Menalia L, Altman MC, Ayars AG.

Ann Allergy Asthma Immunol. 2016 Oct;117(4):378-381. doi: 10.1016/j.anai.2016.07.039. Epub 2016 Aug 31.


Radiologic computed tomography features of Mycobacterium abscessus in cystic fibrosis.

Lam DL, Kapnadak SG, Godwin JD, Kicska GA, Aitken ML, Pipavath SN.

Clin Respir J. 2018 Feb;12(2):459-466. doi: 10.1111/crj.12536. Epub 2016 Aug 22.


Predictors of non-referral of patients with cystic fibrosis for lung transplant evaluation in the United States.

Ramos KJ, Quon BS, Psoter KJ, Lease ED, Mayer-Hamblett N, Aitken ML, Goss CH.

J Cyst Fibros. 2016 Mar;15(2):196-203. doi: 10.1016/j.jcf.2015.11.005. Epub 2015 Dec 17.


A 21-Year-Old Woman With Cystic Fibrosis, Abdominal Pain, and Recent Weight Loss.

Kapnadak SG, Goss CH, Aitken ML.

Chest. 2015 Nov;148(5):e156-e160. doi: 10.1378/chest.15-1124.


Infection control strategies that successfully controlled an outbreak of Mycobacterium abscessus at a cystic fibrosis center.

Kapnadak SG, Hisert KB, Pottinger PS, Limaye AP, Aitken ML.

Am J Infect Control. 2016 Feb;44(2):154-9. doi: 10.1016/j.ajic.2015.08.023. Epub 2015 Oct 9.


Optimising inhaled mannitol for cystic fibrosis in an adult population.

Flume PA, Aitken ML, Bilton D, Agent P, Charlton B, Forster E, Fox HG, Hebestreit H, Kolbe J, Zuckerman JB, Button BM.

Breathe (Sheff). 2015 Mar;11(1):39-48. doi: 10.1183/20734735.021414. Review.


Regional Isolation Drives Bacterial Diversification within Cystic Fibrosis Lungs.

Jorth P, Staudinger BJ, Wu X, Hisert KB, Hayden H, Garudathri J, Harding CL, Radey MC, Rezayat A, Bautista G, Berrington WR, Goddard AF, Zheng C, Angermeyer A, Brittnacher MJ, Kitzman J, Shendure J, Fligner CL, Mittler J, Aitken ML, Manoil C, Bruce JE, Yahr TL, Singh PK.

Cell Host Microbe. 2015 Sep 9;18(3):307-19. doi: 10.1016/j.chom.2015.07.006. Epub 2015 Aug 20.


Gallium Compounds Exhibit Potential as New Therapeutic Agents against Mycobacterium abscessus.

Abdalla MY, Switzer BL, Goss CH, Aitken ML, Singh PK, Britigan BE.

Antimicrob Agents Chemother. 2015 Aug;59(8):4826-34. doi: 10.1128/AAC.00331-15. Epub 2015 Jun 1.


Prevalence of symptoms of depression and anxiety in adults with cystic fibrosis based on the PHQ-9 and GAD-7 screening questionnaires.

Quon BS, Bentham WD, Unutzer J, Chan YF, Goss CH, Aitken ML.

Psychosomatics. 2015 Jul-Aug;56(4):345-53. doi: 10.1016/j.psym.2014.05.017. Epub 2014 Jun 2.


High-level relatedness among Mycobacterium abscessus subsp. massiliense strains from widely separated outbreaks.

Tettelin H, Davidson RM, Agrawal S, Aitken ML, Shallom S, Hasan NA, Strong M, de Moura VC, De Groote MA, Duarte RS, Hine E, Parankush S, Su Q, Daugherty SC, Fraser CM, Brown-Elliott BA, Wallace RJ Jr, Holland SM, Sampaio EP, Olivier KN, Jackson M, Zelazny AM.

Emerg Infect Dis. 2014 Mar;20(3):364-71. doi: 10.3201/eid2003.131106.


Market watch: defining and quantifying the use of personalized medicines.

Hu SX, Aitken ML, Epstein AM, Trusheim MR, Berndt ER.

Nat Rev Drug Discov. 2013 Dec;12(12):896-7. doi: 10.1038/nrd4177. No abstract available.


Rationale and design of a randomized trial of home electronic symptom and lung function monitoring to detect cystic fibrosis pulmonary exacerbations: the early intervention in cystic fibrosis exacerbation (eICE) trial.

Lechtzin N, West N, Allgood S, Wilhelm E, Khan U, Mayer-Hamblett N, Aitken ML, Ramsey BW, Boyle MP, Mogayzel PJ Jr, Goss CH.

Contemp Clin Trials. 2013 Nov;36(2):460-9. doi: 10.1016/j.cct.2013.09.004. Epub 2013 Sep 19.


Hypoglycemia in adults with cystic fibrosis during oral glucose tolerance testing.

Hirsch IB, Janci MM, Goss CH, Aitken ML.

Diabetes Care. 2013 Aug;36(8):e121-2. doi: 10.2337/dc12-1859. No abstract available.


Role of cells and mediators in exercise-induced bronchoconstriction.

Hallstrand TS, Altemeier WA, Aitken ML, Henderson WR Jr.

Immunol Allergy Clin North Am. 2013 Aug;33(3):313-28, vii. doi: 10.1016/j.iac.2013.02.003. Epub 2013 Mar 29. Review.



Quon BS, Mayer-Hamblett N, Aitken ML, Goss CH.

Chest. 2013 Jan;143(1):272. doi: 10.1378/chest.12-2232. No abstract available.


Pooled analysis of two large randomised phase III inhaled mannitol studies in cystic fibrosis.

Bilton D, Bellon G, Charlton B, Cooper P, De Boeck K, Flume PA, Fox HG, Gallagher CG, Geller DE, Haarman EG, Hebestreit HU, Kolbe J, Lapey A, Robinson P, Wu J, Zuckerman JB, Aitken ML; CF301 and CF302 Investigators.

J Cyst Fibros. 2013 Jul;12(4):367-76. doi: 10.1016/j.jcf.2012.11.002. Epub 2012 Dec 9.


Cystic fibrosis: what to expect now in the early adult years.

Quon BS, Aitken ML.

Paediatr Respir Rev. 2012 Dec;13(4):206-14. doi: 10.1016/j.prrv.2012.03.005. Epub 2012 Jun 9. Review.


Disparities in access to lung transplantation for patients with cystic fibrosis by socioeconomic status.

Quon BS, Psoter K, Mayer-Hamblett N, Aitken ML, Li CI, Goss CH.

Am J Respir Crit Care Med. 2012 Nov 15;186(10):1008-13. doi: 10.1164/rccm.201205-0949OC. Epub 2012 Sep 13.


Direct sampling of cystic fibrosis lungs indicates that DNA-based analyses of upper-airway specimens can misrepresent lung microbiota.

Goddard AF, Staudinger BJ, Dowd SE, Joshi-Datar A, Wolcott RD, Aitken ML, Fligner CL, Singh PK.

Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13769-74. doi: 10.1073/pnas.1107435109. Epub 2012 Aug 7.


Chest computed tomography scores are predictive of survival in patients with cystic fibrosis awaiting lung transplantation.

Loeve M, Hop WC, de Bruijne M, van Hal PT, Robinson P, Aitken ML, Dodd JD, Tiddens HA; Computed Tomography Cystic Fibrosis Survival Study Group.

Am J Respir Crit Care Med. 2012 May 15;185(10):1096-103. doi: 10.1164/rccm.201111-2065OC. Epub 2012 Mar 8.


Respiratory outbreak of Mycobacterium abscessus subspecies massiliense in a lung transplant and cystic fibrosis center.

Aitken ML, Limaye A, Pottinger P, Whimbey E, Goss CH, Tonelli MR, Cangelosi GA, Dirac MA, Olivier KN, Brown-Elliott BA, McNulty S, Wallace RJ Jr.

Am J Respir Crit Care Med. 2012 Jan 15;185(2):231-2. No abstract available.


Feasibility of using pedometers to measure daily step counts in cystic fibrosis and an assessment of its responsiveness to changes in health state.

Quon BS, Patrick DL, Edwards TC, Aitken ML, Gibson RL, Genatossio A, McNamara S, Goss CH.

J Cyst Fibros. 2012 May;11(3):216-22. doi: 10.1016/j.jcf.2011.12.002. Epub 2012 Jan 4.


Risk of post-lung transplant renal dysfunction in adults with cystic fibrosis.

Quon BS, Mayer-Hamblett N, Aitken ML, Goss CH.

Chest. 2012 Jul;142(1):185-191. doi: 10.1378/chest.11-1926.


Long-term inhaled dry powder mannitol in cystic fibrosis: an international randomized study.

Aitken ML, Bellon G, De Boeck K, Flume PA, Fox HG, Geller DE, Haarman EG, Hebestreit HU, Lapey A, Schou IM, Zuckerman JB, Charlton B; CF302 Investigators.

Am J Respir Crit Care Med. 2012 Mar 15;185(6):645-52. doi: 10.1164/rccm.201109-1666OC. Epub 2011 Dec 28.


Results of a phase IIa study of VX-809, an investigational CFTR corrector compound, in subjects with cystic fibrosis homozygous for the F508del-CFTR mutation.

Clancy JP, Rowe SM, Accurso FJ, Aitken ML, Amin RS, Ashlock MA, Ballmann M, Boyle MP, Bronsveld I, Campbell PW, De Boeck K, Donaldson SH, Dorkin HL, Dunitz JM, Durie PR, Jain M, Leonard A, McCoy KS, Moss RB, Pilewski JM, Rosenbluth DB, Rubenstein RC, Schechter MS, Botfield M, Ordoñez CL, Spencer-Green GT, Vernillet L, Wisseh S, Yen K, Konstan MW.

Thorax. 2012 Jan;67(1):12-8. doi: 10.1136/thoraxjnl-2011-200393. Epub 2011 Aug 8.


Risk factors for chronic kidney disease in adults with cystic fibrosis.

Quon BS, Mayer-Hamblett N, Aitken ML, Smyth AR, Goss CH.

Am J Respir Crit Care Med. 2011 Nov 15;184(10):1147-52. doi: 10.1164/rccm.201105-0932OC. Epub 2011 Jul 28.


Effect of VX-770 in persons with cystic fibrosis and the G551D-CFTR mutation.

Accurso FJ, Rowe SM, Clancy JP, Boyle MP, Dunitz JM, Durie PR, Sagel SD, Hornick DB, Konstan MW, Donaldson SH, Moss RB, Pilewski JM, Rubenstein RC, Uluer AZ, Aitken ML, Freedman SD, Rose LM, Mayer-Hamblett N, Dong Q, Zha J, Stone AJ, Olson ER, Ordoñez CL, Campbell PW, Ashlock MA, Ramsey BW.

N Engl J Med. 2010 Nov 18;363(21):1991-2003. doi: 10.1056/NEJMoa0909825.


Randomized trial of biofilm testing to select antibiotics for cystic fibrosis airway infection.

Moskowitz SM, Emerson JC, McNamara S, Shell RD, Orenstein DM, Rosenbluth D, Katz MF, Ahrens R, Hornick D, Joseph PM, Gibson RL, Aitken ML, Benton WW, Burns JL.

Pediatr Pulmonol. 2011 Feb;46(2):184-92. doi: 10.1002/ppul.21350. Epub 2010 Oct 20.


Predictors of influenza vaccination in the Cystic Fibrosis Foundation patient registry, 2006 through 2007.

Ortiz JR, Neuzil KM, Victor JC, Aitken ML, Goss CH.

Chest. 2010 Dec;138(6):1448-55. doi: 10.1378/chest.10-0356. Epub 2010 May 21.


Effects of bronchoconstriction, minute ventilation, and deep inspiration on the composition of exhaled breath condensate.

Debley JS, Ohanian AS, Spiekerman CF, Aitken ML, Hallstrand TS.

Chest. 2011 Jan;139(1):16-22. doi: 10.1378/chest.10-0101. Epub 2010 Apr 9.


The use of rim excision as a treatment for canine acanthomatous ameloblastoma.

Murray RL, Aitken ML, Gottfried SD.

J Am Anim Hosp Assoc. 2010 Mar-Apr;46(2):91-6.


Transglutaminase 2, a novel regulator of eicosanoid production in asthma revealed by genome-wide expression profiling of distinct asthma phenotypes.

Hallstrand TS, Wurfel MM, Lai Y, Ni Z, Gelb MH, Altemeier WA, Beyer RP, Aitken ML, Henderson WR.

PLoS One. 2010 Jan 5;5(1):e8583. doi: 10.1371/journal.pone.0008583.

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