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Items: 25


Dextran sulfate sodium (DSS)-induced colitis in mice.

Chassaing B, Aitken JD, Malleshappa M, Vijay-Kumar M.

Curr Protoc Immunol. 2014 Feb 4;104:15.25.1-15.25.14. doi: 10.1002/0471142735.im1525s104.


Gut microbiota in 2012: Toward understanding and manipulating the gut microbiota.

Aitken JD, Gewirtz AT.

Nat Rev Gastroenterol Hepatol. 2013 Feb;10(2):72-4. doi: 10.1038/nrgastro.2012.252. Epub 2013 Jan 8. Review. No abstract available.


Differential role of lipocalin 2 during immune complex-mediated acute and chronic inflammation in mice.

Shashidharamurthy R, Machiah D, Aitken JD, Putty K, Srinivasan G, Chassaing B, Parkos CA, Selvaraj P, Vijay-Kumar M.

Arthritis Rheum. 2013 Apr;65(4):1064-73. doi: 10.1002/art.37840.


Gut microbiota drives metabolic disease in immunologically altered mice.

Chassaing B, Aitken JD, Gewirtz AT, Vijay-Kumar M.

Adv Immunol. 2012;116:93-112. doi: 10.1016/B978-0-12-394300-2.00003-X. Review.


Transient inability to manage proteobacteria promotes chronic gut inflammation in TLR5-deficient mice.

Carvalho FA, Koren O, Goodrich JK, Johansson ME, Nalbantoglu I, Aitken JD, Su Y, Chassaing B, Walters WA, González A, Clemente JC, Cullender TC, Barnich N, Darfeuille-Michaud A, Vijay-Kumar M, Knight R, Ley RE, Gewirtz AT.

Cell Host Microbe. 2012 Aug 16;12(2):139-52. doi: 10.1016/j.chom.2012.07.004. Epub 2012 Aug 2.


Lipocalin 2 deficiency dysregulates iron homeostasis and exacerbates endotoxin-induced sepsis.

Srinivasan G, Aitken JD, Zhang B, Carvalho FA, Chassaing B, Shashidharamurthy R, Borregaard N, Jones DP, Gewirtz AT, Vijay-Kumar M.

J Immunol. 2012 Aug 15;189(4):1911-9. doi: 10.4049/jimmunol.1200892. Epub 2012 Jul 11.


Cytosolic flagellin receptor NLRC4 protects mice against mucosal and systemic challenges.

Carvalho FA, Nalbantoglu I, Aitken JD, Uchiyama R, Su Y, Doho GH, Vijay-Kumar M, Gewirtz AT.

Mucosal Immunol. 2012 May;5(3):288-98. doi: 10.1038/mi.2012.8. Epub 2012 Feb 8.


Toll-like receptor-gut microbiota interactions: perturb at your own risk!

Carvalho FA, Aitken JD, Vijay-Kumar M, Gewirtz AT.

Annu Rev Physiol. 2012;74:177-98. doi: 10.1146/annurev-physiol-020911-153330. Epub 2011 Oct 24. Review.


Interleukin-1β (IL-1β) promotes susceptibility of Toll-like receptor 5 (TLR5) deficient mice to colitis.

Carvalho FA, Nalbantoglu I, Ortega-Fernandez S, Aitken JD, Su Y, Koren O, Walters WA, Knight R, Ley RE, Vijay-Kumar M, Gewirtz AT.

Gut. 2012 Mar;61(3):373-84. doi: 10.1136/gut.2011.240556. Epub 2011 Jun 5.


Fish oil rich diet in comparison to saturated fat rich diet offered protection against lipopolysaccharide-induced inflammation and insulin resistance in mice.

Vijay-Kumar M, Vanegas SM, Patel N, Aitken JD, Ziegler TR, Ganji V.

Nutr Metab (Lond). 2011 Mar 9;8(1):16. doi: 10.1186/1743-7075-8-16.


Loss of function mutation in toll-like receptor-4 does not offer protection against obesity and insulin resistance induced by a diet high in trans fat in mice.

Vijay-Kumar M, Aitken JD, Carvalho FA, Ziegler TR, Gewirtz AT, Ganji V.

J Inflamm (Lond). 2011 Feb 11;8(1):2. doi: 10.1186/1476-9255-8-2.


TLR5 or NLRC4 is necessary and sufficient for promotion of humoral immunity by flagellin.

Vijay-Kumar M, Carvalho FA, Aitken JD, Fifadara NH, Gewirtz AT.

Eur J Immunol. 2010 Dec;40(12):3528-34. doi: 10.1002/eji.201040421.


TLR5 activation induces secretory interleukin-1 receptor antagonist (sIL-1Ra) and reduces inflammasome-associated tissue damage.

Carvalho FA, Aitken JD, Gewirtz AT, Vijay-Kumar M.

Mucosal Immunol. 2011 Jan;4(1):102-11. doi: 10.1038/mi.2010.57. Epub 2010 Sep 15.


Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5.

Vijay-Kumar M, Aitken JD, Carvalho FA, Cullender TC, Mwangi S, Srinivasan S, Sitaraman SV, Knight R, Ley RE, Gewirtz AT.

Science. 2010 Apr 9;328(5975):228-31. doi: 10.1126/science.1179721. Epub 2010 Mar 4.


Flagellin treatment protects against chemicals, bacteria, viruses, and radiation.

Vijay-Kumar M, Aitken JD, Sanders CJ, Frias A, Sloane VM, Xu J, Neish AS, Rojas M, Gewirtz AT.

J Immunol. 2008 Jun 15;180(12):8280-5.


Toll-like receptor 5-deficient mice have dysregulated intestinal gene expression and nonspecific resistance to Salmonella-induced typhoid-like disease.

Vijay-Kumar M, Aitken JD, Kumar A, Neish AS, Uematsu S, Akira S, Gewirtz AT.

Infect Immun. 2008 Mar;76(3):1276-81. doi: 10.1128/IAI.01491-07. Epub 2008 Jan 14.


Toll like receptor-5: protecting the gut from enteric microbes.

Vijay-Kumar M, Aitken JD, Gewirtz AT.

Semin Immunopathol. 2008 Feb;30(1):11-21. Epub 2007 Dec 7. Review.


Deletion of TLR5 results in spontaneous colitis in mice.

Vijay-Kumar M, Sanders CJ, Taylor RT, Kumar A, Aitken JD, Sitaraman SV, Neish AS, Uematsu S, Akira S, Williams IR, Gewirtz AT.

J Clin Invest. 2007 Dec;117(12):3909-21.


Analysis of the interaction between respiratory syncytial virus and lipid-rafts in Hep2 cells during infection.

Brown G, Jeffree CE, McDonald T, Rixon HW, Aitken JD, Sugrue RJ.

Virology. 2004 Oct 1;327(2):175-85.


pH reduction as a trigger for dissociation of herpes simplex virus type 1 scaffolds.

McClelland DA, Aitken JD, Bhella D, McNab D, Mitchell J, Kelly SM, Price NC, Rixon FJ.

J Virol. 2002 Aug;76(15):7407-17.


The products of human cytomegalovirus genes UL23, UL24, UL43 and US22 are tegument components.

Adair R, Douglas ER, Maclean JB, Graham SY, Aitken JD, Jamieson FE, Dargan DJ.

J Gen Virol. 2002 Jun;83(Pt 6):1315-24.


The role of the gene 71 product in the life cycle of equine herpesvirus 1.

Sun Y, MacLean AR, Aitken JD, Brown SM.

J Gen Virol. 1996 Mar;77 ( Pt 3):493-500.


ICP34.5 influences herpes simplex virus type 1 maturation and egress from infected cells in vitro.

Brown SM, MacLean AR, Aitken JD, Harland J.

J Gen Virol. 1994 Dec;75 ( Pt 12):3679-86.


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