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Items: 10


Synthesis of the Core Framework of the Cornexistins by Intramolecular Nozaki-Hiyama-Kishi Coupling.

Aimon A, Farrugia LJ, Clark JS.

Molecules. 2019 Jul 22;24(14). pii: E2654. doi: 10.3390/molecules24142654.


Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening.

Resnick E, Bradley A, Gan J, Douangamath A, Krojer T, Sethi R, Geurink PP, Aimon A, Amitai G, Bellini D, Bennett J, Fairhead M, Fedorov O, Gabizon R, Gan J, Guo J, Plotnikov A, Reznik N, Ruda GF, Díaz-Sáez L, Straub VM, Szommer T, Velupillai S, Zaidman D, Zhang Y, Coker AR, Dowson CG, Barr HM, Wang C, Huber KVM, Brennan PE, Ovaa H, von Delft F, London N.

J Am Chem Soc. 2019 Jun 5;141(22):8951-8968. doi: 10.1021/jacs.9b02822. Epub 2019 May 22.


Translation of innovative chemistry into screening libraries: an exemplar partnership from the European Lead Factory.

Morgentin R, Dow M, Aimon A, Karageorgis G, Kalliokoski T, Roche D, Marsden S, Nelson A.

Drug Discov Today. 2018 Sep;23(9):1578-1583. doi: 10.1016/j.drudis.2018.05.007. Epub 2018 May 9. Review.


Realisation of small molecule libraries based on frameworks distantly related to natural products.

Aimon A, Karageorgis G, Masters J, Dow M, Craven PGE, Ohsten M, Willaume A, Morgentin R, Ruiz-Llamas N, Lemoine H, Kalliokoski T, Eatherton AJ, Foley DJ, Marsden SP, Nelson A.

Org Biomol Chem. 2018 May 2;16(17):3160-3167. doi: 10.1039/c8ob00688a.


Synthesis and Demonstration of the Biological Relevance of sp3 -rich Scaffolds Distantly Related to Natural Product Frameworks.

Foley DJ, Craven PGE, Collins PM, Doveston RG, Aimon A, Talon R, Churcher I, von Delft F, Marsden SP, Nelson A.

Chemistry. 2017 Oct 26;23(60):15227-15232. doi: 10.1002/chem.201704169. Epub 2017 Oct 6.


Role of C-N Configurations in the Photoluminescence of Graphene Quantum Dots Synthesized by a Hydrothermal Route.

Permatasari FA, Aimon AH, Iskandar F, Ogi T, Okuyama K.

Sci Rep. 2016 Feb 15;6:21042. doi: 10.1038/srep21042.


Activity-Directed Synthesis with Intermolecular Reactions: Development of a Fragment into a Range of Androgen Receptor Agonists.

Karageorgis G, Dow M, Aimon A, Warriner S, Nelson A.

Angew Chem Int Ed Engl. 2015 Nov 9;54(46):13538-44. doi: 10.1002/anie.201506944. Epub 2015 Sep 11.


Design, synthesis and decoration of molecular scaffolds for exploitation in the production of alkaloid-like libraries.

Craven P, Aimon A, Dow M, Fleury-Bregeot N, Guilleux R, Morgentin R, Roche D, Kalliokoski T, Foster R, Marsden SP, Nelson A.

Bioorg Med Chem. 2015 Jun 1;23(11):2629-35. doi: 10.1016/j.bmc.2014.12.048. Epub 2014 Dec 29.


Organocatalytic synthesis of highly substituted furfuryl alcohols and amines.

Clark JS, Boyer A, Aimon A, Engel García P, Lindsay DM, Symington AD, Danoy Y.

Angew Chem Int Ed Engl. 2012 Nov 26;51(48):12128-31. doi: 10.1002/anie.201207300. Epub 2012 Oct 24. No abstract available.


The molecularly controlled synthesis of ordered bi-dimensional C60 arrays.

Gengler RY, Gournis D, Aimon AH, Toma LM, Rudolf P.

Chemistry. 2012 Jun 11;18(24):7594-600. doi: 10.1002/chem.201103528. Epub 2012 Apr 20.


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