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Pneumomediastinum as a complication of cocaine abuse.

Macrae C, Brown C, Aiken C, Jamdar R.

Clin Med (Lond). 2019 Jul;19(4):321-324. doi: 10.7861/clinmedicine.19-4-321.


A novel phenotype links HIV-1 capsid stability to cGAS-mediated DNA sensing.

Siddiqui MA, Saito A, Halambage UD, Ferhadian D, Fischer DK, Francis AC, Melikyan GB, Ambrose Z, Aiken C, Yamashita M.

J Virol. 2019 Jun 5. pii: JVI.00706-19. doi: 10.1128/JVI.00706-19. [Epub ahead of print]


Functional analysis of the secondary HIV-1 capsid binding site in the host protein cyclophilin A.

Peng W, Shi J, Márquez CL, Lau D, Walsh J, Faysal KMR, Byeon CH, Byeon IL, Aiken C, Böcking T.

Retrovirology. 2019 Apr 4;16(1):10. doi: 10.1186/s12977-019-0471-4.


Chronic gestational hypoxia accelerates ovarian aging and lowers ovarian reserve in next-generation adult rats.

Aiken CE, Tarry-Adkins JL, Spiroski AM, Nuzzo AM, Ashmore TJ, Rolfo A, Sutherland MJ, Camm EJ, Giussani DA, Ozanne SE.

FASEB J. 2019 Jun;33(6):7758-7766. doi: 10.1096/fj.201802772R. Epub 2019 Mar 19.


Early life environment influences the trajectory of post-partum weight loss in adult female rats.

Aiken CE, Tarry-Adkins JL, Ashmore TJ, Ozanne SE.

Reprod Biomed Online. 2019 May;38(5):779-786. doi: 10.1016/j.rbmo.2018.12.002. Epub 2018 Dec 12.


Chronic fetal hypoxia disrupts the peri-conceptual environment in next-generation adult female rats.

Aiken CE, Tarry-Adkins JL, Spiroski AM, Nuzzo AM, Ashmore TJ, Rolfo A, Sutherland MJ, Camm EJ, Giussani DA, Ozanne SE.

J Physiol. 2019 May;597(9):2391-2401. doi: 10.1113/JP277431. Epub 2019 Mar 24.


PF74 Inhibits HIV-1 Integration by Altering the Composition of the Preintegration Complex.

Balasubramaniam M, Zhou J, Addai A, Martinez P, Pandhare J, Aiken C, Dash C.

J Virol. 2019 Mar 5;93(6). pii: e01741-18. doi: 10.1128/JVI.01741-18. Print 2019 Mar 15.


Assaying Reproductive Capacity in Female Rodents.

Aiken CE, Tarry-Adkins JL, Ozanne SE.

Methods Mol Biol. 2019;1916:157-166. doi: 10.1007/978-1-4939-8994-2_15.


Effects of Exergaming on Physical and Cognitive Functions in Individuals with Autism Spectrum Disorder: A Systematic Review.

Fang Q, Aiken CA, Fang C, Pan Z.

Games Health J. 2019 Apr;8(2):74-84. doi: 10.1089/g4h.2018.0032. Epub 2018 Oct 17. Review.


Maternal exercise intervention in obese pregnancy improves the cardiovascular health of the adult male offspring.

Beeson JH, Blackmore HL, Carr SK, Dearden L, Duque-Guimarães DE, Kusinski LC, Pantaleão LC, Pinnock AG, Aiken CE, Giussani DA, Fernandez-Twinn DS, Ozanne SE.

Mol Metab. 2018 Oct;16:35-44. doi: 10.1016/j.molmet.2018.06.009. Epub 2018 Jun 18.


PF74 Reinforces the HIV-1 Capsid To Impair Reverse Transcription-Induced Uncoating.

Rankovic S, Ramalho R, Aiken C, Rousso I.

J Virol. 2018 Sep 26;92(20). pii: e00845-18. doi: 10.1128/JVI.00845-18. Print 2018 Oct 15.


HIV-1 Engages a Dynein-Dynactin-BICD2 Complex for Infection and Transport to the Nucleus.

Carnes SK, Zhou J, Aiken C.

J Virol. 2018 Sep 26;92(20). pii: e00358-18. doi: 10.1128/JVI.00358-18. Print 2018 Oct 15.


A suboptimal maternal diet combined with accelerated postnatal growth results in an altered aging profile in the thymus of male rats.

Tarry-Adkins JL, Aiken CE, Ashmore TJ, Fernandez-Twinn DS, Chen JH, Ozanne SE.

FASEB J. 2019 Jan;33(1):239-253. doi: 10.1096/fj.201701350RR. Epub 2018 Jul 5.


Improving outcomes in gestational diabetes: does gestational weight gain matter?

Aiken CEM, Hone L, Murphy HR, Meek CL.

Diabet Med. 2019 Feb;36(2):167-176. doi: 10.1111/dme.13767. Epub 2018 Jul 11.


Inhibitors of the HIV-1 capsid, a target of opportunity.

Carnes SK, Sheehan JH, Aiken C.

Curr Opin HIV AIDS. 2018 Jul;13(4):359-365. doi: 10.1097/COH.0000000000000472. Review.


Maternal diet-induced obesity programmes cardiac dysfunction in male mice independently of post-weaning diet.

Loche E, Blackmore HL, Carpenter AA, Beeson JH, Pinnock A, Ashmore TJ, Aiken CE, de Almeida-Faria J, Schoonejans JM, Giussani DA, Fernandez-Twinn DS, Ozanne SE.

Cardiovasc Res. 2018 Aug 1;114(10):1372-1384. doi: 10.1093/cvr/cvy082.


Insulin-signalling dysregulation and inflammation is programmed trans-generationally in a female rat model of poor maternal nutrition.

Tarry-Adkins JL, Aiken CE, Ashmore TJ, Ozanne SE.

Sci Rep. 2018 Mar 5;8(1):4014. doi: 10.1038/s41598-018-22383-w.


Observed Interactions in Families of Adolescent Suicide Attempters.

Aiken CS, Wagner BM, Benjamin Hinnant J.

Suicide Life Threat Behav. 2019 Feb;49(1):104-119. doi: 10.1111/sltb.12423. Epub 2017 Dec 1.


Quenching protein dynamics interferes with HIV capsid maturation.

Wang M, Quinn CM, Perilla JR, Zhang H, Shirra R Jr, Hou G, Byeon IJ, Suiter CL, Ablan S, Urano E, Nitz TJ, Aiken C, Freed EO, Zhang P, Schulten K, Gronenborn AM, Polenova T.

Nat Commun. 2017 Nov 24;8(1):1779. doi: 10.1038/s41467-017-01856-y.


Contributions of Function-Altering Variants in Genes Implicated in Pubertal Timing and Body Mass for Self-Limited Delayed Puberty.

Howard SR, Guasti L, Poliandri A, David A, Cabrera CP, Barnes MR, Wehkalampi K, O'Rahilly S, Aiken CE, Coll AP, Ma M, Rimmington D, Yeo GSH, Dunkel L.

J Clin Endocrinol Metab. 2018 Feb 1;103(2):649-659. doi: 10.1210/jc.2017-02147.


The effects of a two-step transfer on a visuomotor adaptation task.

Aiken CA, Pan Z, Van Gemmert AWA.

Exp Brain Res. 2017 Nov;235(11):3459-3467. doi: 10.1007/s00221-017-5071-8. Epub 2017 Aug 24.


Cyclophilin A potentiates TRIM5α inhibition of HIV-1 nuclear import without promoting TRIM5α binding to the viral capsid.

Burse M, Shi J, Aiken C.

PLoS One. 2017 Aug 2;12(8):e0182298. doi: 10.1371/journal.pone.0182298. eCollection 2017.


Measuring Spatially Resolved Collective Ionic Transport on Lithium Battery Cathodes Using Atomic Force Microscopy.

Mascaro A, Wang Z, Hovington P, Miyahara Y, Paolella A, Gariepy V, Feng Z, Enright T, Aiken C, Zaghib K, Bevan KH, Grutter P.

Nano Lett. 2017 Jul 12;17(7):4489-4496. doi: 10.1021/acs.nanolett.7b01857. Epub 2017 Jun 21.


Reverse Transcription Mechanically Initiates HIV-1 Capsid Disassembly.

Rankovic S, Varadarajan J, Ramalho R, Aiken C, Rousso I.

J Virol. 2017 May 26;91(12). pii: e00289-17. doi: 10.1128/JVI.00289-17. Print 2017 Jun 15.


Inhibition of HIV-1 Maturation via Small-Molecule Targeting of the Amino-Terminal Domain in the Viral Capsid Protein.

Wang W, Zhou J, Halambage UD, Jurado KA, Jamin AV, Wang Y, Engelman AN, Aiken C.

J Virol. 2017 Apr 13;91(9). pii: e02155-16. doi: 10.1128/JVI.02155-16. Print 2017 May 1.


Breaking the cycle of intergenerational obesity.

Aiken CE, Ozanne SE.

J Physiol. 2017 Mar 1;595(5):1443-1444. doi: 10.1113/JP273821. Epub 2017 Feb 1. No abstract available.


In vitro protease cleavage and computer simulations reveal the HIV-1 capsid maturation pathway.

Ning J, Erdemci-Tandogan G, Yufenyuy EL, Wagner J, Himes BA, Zhao G, Aiken C, Zandi R, Zhang P.

Nat Commun. 2016 Dec 13;7:13689. doi: 10.1038/ncomms13689.


Contraceptive method preferences and provision after termination of pregnancy: a population-based analysis of women obtaining care with the British Pregnancy Advisory Service.

Aiken A, Lohr PA, Aiken CE, Forsyth T, Trussell J.

BJOG. 2017 Apr;124(5):815-824. doi: 10.1111/1471-0528.14413. Epub 2016 Nov 14.


The influence of hours worked prior to delivery on maternal and neonatal outcomes: a retrospective cohort study.

Aiken CE, Aiken AR, Scott JG, Brockelsby JC.

Am J Obstet Gynecol. 2016 Nov;215(5):634.e1-634.e7. doi: 10.1016/j.ajog.2016.06.026. Epub 2016 Jun 23.


In the midst of Zika pregnancy advisories, termination of pregnancy is the elephant in the room.

Aiken A, Aiken CE, Trussell J.

BJOG. 2017 Mar;124(4):546-548. doi: 10.1111/1471-0528.14296. Epub 2016 Sep 5. No abstract available.


Poor maternal nutrition and accelerated postnatal growth induces an accelerated aging phenotype and oxidative stress in skeletal muscle of male rats.

Tarry-Adkins JL, Fernandez-Twinn DS, Chen JH, Hargreaves IP, Neergheen V, Aiken CE, Ozanne SE.

Dis Model Mech. 2016 Oct 1;9(10):1221-1229. Epub 2016 Sep 1.


Structure and Glycan Binding of a New Cyanovirin-N Homolog.

Matei E, Basu R, Furey W, Shi J, Calnan C, Aiken C, Gronenborn AM.

J Biol Chem. 2016 Sep 2;291(36):18967-76. doi: 10.1074/jbc.M116.740415. Epub 2016 Jul 7.


TACTIC: a multicentre, open-label, single-arm phase II trial of panitumumab, cisplatin, and gemcitabine in biliary tract cancer.

Ferraro D, Goldstein D, O'Connell RL, Zalcberg JR, Sjoquist KM, Tebbutt NC, Grimison P, McLachlan S, Lipton LL, Vasey P, Gebski VJ, Aiken C, Cronk M, Ng S, Karapetis CS, Shannon J; behalf of the the Australasian Gastro-Intestinal Trials Group.

Cancer Chemother Pharmacol. 2016 Aug;78(2):361-7. doi: 10.1007/s00280-016-3089-4. Epub 2016 Jun 22.


Requests for Abortion in Latin America Related to Concern about Zika Virus Exposure.

Aiken AR, Scott JG, Gomperts R, Trussell J, Worrell M, Aiken CE.

N Engl J Med. 2016 Jul 28;375(4):396-8. doi: 10.1056/NEJMc1605389. Epub 2016 Jun 22. No abstract available.


Time-Resolved Imaging of Single HIV-1 Uncoating In Vitro and in Living Cells.

Francis AC, Marin M, Shi J, Aiken C, Melikyan GB.

PLoS Pathog. 2016 Jun 20;12(6):e1005709. doi: 10.1371/journal.ppat.1005709. eCollection 2016 Jun.


Transgenerational effects of maternal diet on metabolic and reproductive ageing.

Aiken CE, Tarry-Adkins JL, Ozanne SE.

Mamm Genome. 2016 Aug;27(7-8):430-9. doi: 10.1007/s00335-016-9631-1. Epub 2016 Apr 25. Review.


Roles of Capsid-Interacting Host Factors in Multimodal Inhibition of HIV-1 by PF74.

Saito A, Ferhadian D, Sowd GA, Serrao E, Shi J, Halambage UD, Teng S, Soto J, Siddiqui MA, Engelman AN, Aiken C, Yamashita M.

J Virol. 2016 May 27;90(12):5808-5823. doi: 10.1128/JVI.03116-15. Print 2016 Jun 15.


Analysis of the mechanical properties of wild type and hyperstable mutants of the HIV-1 capsid.

Ramalho R, Rankovic S, Zhou J, Aiken C, Rousso I.

Retrovirology. 2016 Mar 15;13:17. doi: 10.1186/s12977-016-0250-4.


Assessing Hepatitis C Burden and Treatment Effectiveness through the British Columbia Hepatitis Testers Cohort (BC-HTC): Design and Characteristics of Linked and Unlinked Participants.

Janjua NZ, Kuo M, Chong M, Yu A, Alvarez M, Cook D, Armour R, Aiken C, Li K, Mussavi Rizi SA, Woods R, Godfrey D, Wong J, Gilbert M, Tyndall MW, Krajden M.

PLoS One. 2016 Mar 8;11(3):e0150176. doi: 10.1371/journal.pone.0150176. eCollection 2016.


Cyclophilin A stabilizes the HIV-1 capsid through a novel non-canonical binding site.

Liu C, Perilla JR, Ning J, Lu M, Hou G, Ramalho R, Himes BA, Zhao G, Bedwell GJ, Byeon IJ, Ahn J, Gronenborn AM, Prevelige PE, Rousso I, Aiken C, Polenova T, Schulten K, Zhang P.

Nat Commun. 2016 Mar 4;7:10714. doi: 10.1038/ncomms10714.


Weekend working: a retrospective cohort study of maternal and neonatal outcomes in a large NHS delivery unit.

Aiken CE, Aiken AR, Scott JG, Brockelsby JC, Trussell J.

Eur J Obstet Gynecol Reprod Biol. 2016 Apr;199:5-10. doi: 10.1016/j.ejogrb.2016.01.034. Epub 2016 Feb 6.


Self-control over combined video feedback and modeling facilitates motor learning.

Post PG, Aiken CA, Laughlin DD, Fairbrother JT.

Hum Mov Sci. 2016 Jun;47:49-59. doi: 10.1016/j.humov.2016.01.014. Epub 2016 Feb 11.


Coenzyme Q10 prevents hepatic fibrosis, inflammation, and oxidative stress in a male rat model of poor maternal nutrition and accelerated postnatal growth.

Tarry-Adkins JL, Fernandez-Twinn DS, Hargreaves IP, Neergheen V, Aiken CE, Martin-Gronert MS, McConnell JM, Ozanne SE.

Am J Clin Nutr. 2016 Feb;103(2):579-88. doi: 10.3945/ajcn.115.119834. Epub 2015 Dec 30.


Decreased ovarian reserve, dysregulation of mitochondrial biogenesis, and increased lipid peroxidation in female mouse offspring exposed to an obesogenic maternal diet.

Aiken CE, Tarry-Adkins JL, Penfold NC, Dearden L, Ozanne SE.

FASEB J. 2016 Apr;30(4):1548-56. doi: 10.1096/fj.15-280800. Epub 2015 Dec 23.


Dynamic allostery governs cyclophilin A-HIV capsid interplay.

Lu M, Hou G, Zhang H, Suiter CL, Ahn J, Byeon IJ, Perilla JR, Langmead CJ, Hung I, Gor'kov PL, Gan Z, Brey W, Aiken C, Zhang P, Schulten K, Gronenborn AM, Polenova T.

Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):14617-22. doi: 10.1073/pnas.1516920112. Epub 2015 Nov 9.


Transgenerational Developmental Programming of Ovarian Reserve.

Aiken CE, Tarry-Adkins JL, Ozanne SE.

Sci Rep. 2015 Nov 3;5:16175. doi: 10.1038/srep16175.


Fluorescent protein-tagged Vpr dissociates from HIV-1 core after viral fusion and rapidly enters the cell nucleus.

Desai TM, Marin M, Sood C, Shi J, Nawaz F, Aiken C, Melikyan GB.

Retrovirology. 2015 Oct 29;12:88. doi: 10.1186/s12977-015-0215-z.


Characterization of novel biomarkers in selecting for subtype specific medulloblastoma phenotypes.

Liang L, Aiken C, McClelland R, Morrison LC, Tatari N, Remke M, Ramaswamy V, Issaivanan M, Ryken T, Del Bigio MR, Taylor MD, Werbowetski-Ogilvie TE.

Oncotarget. 2015 Nov 17;6(36):38881-900. doi: 10.18632/oncotarget.6195.


HIV: Antiviral action countered by Nef.

Aiken C.

Nature. 2015 Oct 8;526(7572):202-3. doi: 10.1038/nature15637. Epub 2015 Sep 30. No abstract available.


OTX2 exhibits cell-context-dependent effects on cellular and molecular properties of human embryonic neural precursors and medulloblastoma cells.

Kaur R, Aiken C, Morrison LC, Rao R, Del Bigio MR, Rampalli S, Werbowetski-Ogilvie T.

Dis Model Mech. 2015 Oct 1;8(10):1295-309. doi: 10.1242/dmm.020594. Epub 2015 Aug 6.

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