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Items: 1 to 50 of 594

1.

Multi-organ systems study reveals Igfbp7 as a suppressor of gluconeogenesis after gastric bypass surgery.

Arima N, Sasaki Y, Lee LH, Zhang H, Figueiredo JL, Mlynarchik AK, Qiao J, Yamada I, Higashi H, Ha AH, Halu A, Mizuno K, Singh SA, Yamazaki Y, Aikawa M.

J Proteome Res. 2019 Oct 29. doi: 10.1021/acs.jproteome.9b00441. [Epub ahead of print]

PMID:
31661273
2.

Editorial: New Trends in Vascular Inflammation Research: From Biology to Therapy.

Aikawa M, Manabe I, Marx N.

Front Cardiovasc Med. 2019 Aug 28;6:102. doi: 10.3389/fcvm.2019.00102. eCollection 2019. No abstract available.

3.

Effects of Replacing Dietary Monounsaturated Fat With Carbohydrate on HDL (High-Density Lipoprotein) Protein Metabolism and Proteome Composition in Humans.

Andraski AB, Singh SA, Lee LH, Higashi H, Smith N, Zhang B, Aikawa M, Sacks FM.

Arterioscler Thromb Vasc Biol. 2019 Nov;39(11):2411-2430. doi: 10.1161/ATVBAHA.119.312889. Epub 2019 Sep 26.

PMID:
31554421
4.

Occurrence of Cortical Arousal at Recovery from Respiratory Disturbances during Deep Propofol Sedation.

Urahama R, Uesato M, Aikawa M, Kunii R, Isono S, Matsubara H.

Int J Environ Res Public Health. 2019 Sep 18;16(18). pii: E3482. doi: 10.3390/ijerph16183482.

5.

Production cross sections of ytterbium and thulium radioisotopes in alpha-induced nuclear reactions on natural erbium.

Saito M, Aikawa M, Sakaguchi M, Ukon N, Komori Y, Haba H.

Appl Radiat Isot. 2019 Dec;154:108874. doi: 10.1016/j.apradiso.2019.108874. Epub 2019 Aug 21.

PMID:
31470189
6.

Immigration, coping, and well-being: Implications for communities' roles in promoting the well-being of immigrants and refugees.

Aikawa M, Kleyman K.

J Prev Interv Community. 2019 Jun 28:1-12. doi: 10.1080/10852352.2019.1633066. [Epub ahead of print]

PMID:
31250737
7.

The selective peroxisome proliferator-activated receptor alpha modulator (SPPARMα) paradigm: conceptual framework and therapeutic potential : A consensus statement from the International Atherosclerosis Society (IAS) and the Residual Risk Reduction Initiative (R3i) Foundation.

Fruchart JC, Santos RD, Aguilar-Salinas C, Aikawa M, Al Rasadi K, Amarenco P, Barter PJ, Ceska R, Corsini A, Després JP, Duriez P, Eckel RH, Ezhov MV, Farnier M, Ginsberg HN, Hermans MP, Ishibashi S, Karpe F, Kodama T, Koenig W, Krempf M, Lim S, Lorenzatti AJ, McPherson R, Nuñez-Cortes JM, Nordestgaard BG, Ogawa H, Packard CJ, Plutzky J, Ponte-Negretti CI, Pradhan A, Ray KK, Reiner Ž, Ridker PM, Ruscica M, Sadikot S, Shimano H, Sritara P, Stock JK, Su TC, Susekov AV, Tartar A, Taskinen MR, Tenenbaum A, Tokgözoğlu LS, Tomlinson B, Tybjærg-Hansen A, Valensi P, Vrablík M, Wahli W, Watts GF, Yamashita S, Yokote K, Zambon A, Libby P.

Cardiovasc Diabetol. 2019 Jun 4;18(1):71. doi: 10.1186/s12933-019-0864-7. Review.

8.

The coronavirus macrodomain is required to prevent PARP-mediated inhibition of virus replication and enhancement of IFN expression.

Grunewald ME, Chen Y, Kuny C, Maejima T, Lease R, Ferraris D, Aikawa M, Sullivan CS, Perlman S, Fehr AR.

PLoS Pathog. 2019 May 16;15(5):e1007756. doi: 10.1371/journal.ppat.1007756. eCollection 2019 May.

9.

[18F]FMISO PET/CT as a preoperative prognostic factor in patients with pancreatic cancer.

Yamane T, Aikawa M, Yasuda M, Fukushima K, Seto A, Okamoto K, Koyama I, Kuji I.

EJNMMI Res. 2019 May 9;9(1):39. doi: 10.1186/s13550-019-0507-8.

10.

Standardization of Human Calcific Aortic Valve Disease in vitro Modeling Reveals Passage-Dependent Calcification.

Goto S, Rogers MA, Blaser MC, Higashi H, Lee LH, Schlotter F, Body SC, Aikawa M, Singh SA, Aikawa E.

Front Cardiovasc Med. 2019 Apr 16;6:49. doi: 10.3389/fcvm.2019.00049. eCollection 2019.

11.

Characteristics and risk assessments of heavy metals in fine and coarse particles in an industrial area of central China.

Zhang X, Zhang K, Lv W, Liu B, Aikawa M, Wang J.

Ecotoxicol Environ Saf. 2019 Sep 15;179:1-8. doi: 10.1016/j.ecoenv.2019.04.024. Epub 2019 Apr 22.

PMID:
31022650
12.

A Study into the ADP-Ribosylome of IFN-γ-Stimulated THP-1 Human Macrophage-like Cells Identifies ARTD8/PARP14 and ARTD9/PARP9 ADP-Ribosylation.

Higashi H, Maejima T, Lee LH, Yamazaki Y, Hottiger MO, Singh SA, Aikawa M.

J Proteome Res. 2019 Apr 5;18(4):1607-1622. doi: 10.1021/acs.jproteome.8b00895. Epub 2019 Mar 21.

13.

After 50 Years of Heart Transplants: What Does the Next 50 Years Hold for Cardiovascular Medicine? A Perspective From the International Society for Applied Cardiovascular Biology.

Hutcheson JD, Goergen CJ, Schoen FJ, Aikawa M, Zilla P, Aikawa E, Gaudette GR.

Front Cardiovasc Med. 2019 Feb 14;6:8. doi: 10.3389/fcvm.2019.00008. eCollection 2019.

14.

18F-Fluoride Signal Amplification Identifies Microcalcifications Associated With Atherosclerotic Plaque Instability in Positron Emission Tomography/Computed Tomography Images.

Creager MD, Hohl T, Hutcheson JD, Moss AJ, Schlotter F, Blaser MC, Park MA, Lee LH, Singh SA, Alcaide-Corral CJ, Tavares AAS, Newby DE, Kijewski MF, Aikawa M, Di Carli M, Dweck MR, Aikawa E.

Circ Cardiovasc Imaging. 2019 Jan;12(1):e007835. doi: 10.1161/CIRCIMAGING.118.007835.

PMID:
30642216
15.

Uremic Toxin Indoxyl Sulfate Promotes Proinflammatory Macrophage Activation Via the Interplay of OATP2B1 and Dll4-Notch Signaling.

Nakano T, Katsuki S, Chen M, Decano JL, Halu A, Lee LH, Pestana DVS, Kum AST, Kuromoto RK, Golden WS, Boff MS, Guimaraes GC, Higashi H, Kauffman KJ, Maejima T, Suzuki T, Iwata H, Barabási AL, Aster JC, Anderson DG, Sharma A, Singh SA, Aikawa E, Aikawa M.

Circulation. 2019 Jan 2;139(1):78-96. doi: 10.1161/CIRCULATIONAHA.118.034588.

PMID:
30586693
16.

Production cross sections of Mo, Nb and Zr radioisotopes from α-induced reaction on natZr.

Murata T, Aikawa M, Saito M, Ukon N, Komori Y, Haba H, Takács S.

Appl Radiat Isot. 2019 Feb;144:47-53. doi: 10.1016/j.apradiso.2018.11.012. Epub 2018 Nov 26.

PMID:
30529495
17.

Polysomnographic assessment of respiratory disturbance during deep propofol sedation for endoscopic submucosal dissection of gastric tumors.

Urahama R, Uesato M, Aikawa M, Yamaguchi Y, Hayano K, Matsumura T, Arai M, Kunii R, Isono S, Matsubara H.

World J Gastrointest Endosc. 2018 Nov 16;10(11):340-347. doi: 10.4253/wjge.v10.i11.340.

18.

XINA: A Workflow for the Integration of Multiplexed Proteomics Kinetics Data with Network Analysis.

Lee LH, Halu A, Morgan S, Iwata H, Aikawa M, Singh SA.

J Proteome Res. 2019 Feb 1;18(2):775-781. doi: 10.1021/acs.jproteome.8b00615. Epub 2018 Oct 29.

PMID:
30370770
19.

Context-enriched interactome powered by proteomics helps the identification of novel regulators of macrophage activation.

Halu A, Wang JG, Iwata H, Mojcher A, Abib AL, Singh SA, Aikawa M, Sharma A.

Elife. 2018 Oct 10;7. pii: e37059. doi: 10.7554/eLife.37059.

20.

Dynamic Macrophages: Understanding Mechanisms of Activation as Guide to Therapy for Atherosclerotic Vascular Disease.

Decano JL, Aikawa M.

Front Cardiovasc Med. 2018 Aug 3;5:97. doi: 10.3389/fcvm.2018.00097. eCollection 2018. Review.

21.

Controllability in an islet specific regulatory network identifies the transcriptional factor NFATC4, which regulates Type 2 Diabetes associated genes.

Sharma A, Halu A, Decano JL, Padi M, Liu YY, Prasad RB, Fadista J, Santolini M, Menche J, Weiss ST, Vidal M, Silverman EK, Aikawa M, Barabási AL, Groop L, Loscalzo J.

NPJ Syst Biol Appl. 2018 Jul 3;4:25. doi: 10.1038/s41540-018-0057-0. eCollection 2018.

22.

Transcriptional control of intestinal cholesterol absorption, adipose energy expenditure and lipid handling by Sortilin.

Hagita S, Rogers MA, Pham T, Wen JR, Mlynarchik AK, Aikawa M, Aikawa E.

Sci Rep. 2018 Jun 13;8(1):9006. doi: 10.1038/s41598-018-27416-y.

23.

Engineering a 3D-Bioprinted Model of Human Heart Valve Disease Using Nanoindentation-Based Biomechanics.

van der Valk DC, van der Ven CFT, Blaser MC, Grolman JM, Wu PJ, Fenton OS, Lee LH, Tibbitt MW, Andresen JL, Wen JR, Ha AH, Buffolo F, van Mil A, Bouten CVC, Body SC, Mooney DJ, Sluijter JPG, Aikawa M, Hjortnaes J, Langer R, Aikawa E.

Nanomaterials (Basel). 2018 May 3;8(5). pii: E296. doi: 10.3390/nano8050296.

24.

Spatiotemporal Multi-Omics Mapping Generates a Molecular Atlas of the Aortic Valve and Reveals Networks Driving Disease.

Schlotter F, Halu A, Goto S, Blaser MC, Body SC, Lee LH, Higashi H, DeLaughter DM, Hutcheson JD, Vyas P, Pham T, Rogers MA, Sharma A, Seidman CE, Loscalzo J, Seidman JG, Aikawa M, Singh SA, Aikawa E.

Circulation. 2018 Jul 24;138(4):377-393. doi: 10.1161/CIRCULATIONAHA.117.032291.

25.

Measurement of activation cross sections of alpha particle induced reactions on iridium up to an energy of 50 MeV.

Takács S, Ditrói F, Szűcs Z, Aikawa M, Haba H, Komori Y, Saito M.

Appl Radiat Isot. 2018 Jun;136:133-142. doi: 10.1016/j.apradiso.2018.02.023. Epub 2018 Feb 22.

PMID:
29499445
26.

[Surgical Therapy for Locally Recurrent Rectal Cancer].

Hara K, Yamaguchi S, Ishii T, Tashiro J, Kondo H, Shimizu H, Takemoto K, Suzuki A, Ishikawa S, Okada T, Aikawa M, Sato H, Okamoto K, Sakuramoto S, Koyama I.

Gan To Kagaku Ryoho. 2017 Nov;44(12):1769-1771. Japanese.

PMID:
29394770
27.

Dimerization of sortilin regulates its trafficking to extracellular vesicles.

Itoh S, Mizuno K, Aikawa M, Aikawa E.

J Biol Chem. 2018 Mar 23;293(12):4532-4544. doi: 10.1074/jbc.RA117.000732. Epub 2018 Jan 30.

28.

[The Efficacy of Definitive Chemoradiotherapy for Thoracic Esophageal Cancer on the Point of View Salvage Surgery].

Sato H, Miyawaki Y, Kasuya M, Aratani K, Chuman M, Gunji H, Aikawa M, Okamoto K, Sakuramoto S, Yamaguchi S, Koyama I.

Gan To Kagaku Ryoho. 2018 Jan;45(1):97-99. Japanese.

PMID:
29362320
29.

Laparoscopic liver resection using a monopolar soft-coagulation device to provide maximum intraoperative bleeding control for the treatment of hepatocellular carcinoma.

Miyazawa M, Aikawa M, Okada K, Watanabe Y, Okamoto K, Koyama I.

Surg Endosc. 2018 Apr;32(4):2157-2158. doi: 10.1007/s00464-017-5829-x. Epub 2017 Sep 15.

PMID:
28916868
30.

Comparison of Efficacy of Self-Expandable Metallic Stent Placement in the Unresectable Esophageal Cancer Patients.

Uesato M, Akutsu Y, Murakami K, Muto Y, Kagaya A, Nakano A, Aikawa M, Tamachi T, Arasawa T, Amagai H, Muto Y, Matsubara H.

Gastroenterol Res Pract. 2017;2017:2560510. doi: 10.1155/2017/2560510. Epub 2017 Jul 27.

31.

Endoscopic occlusion with silicone spigots for the closure of refractory esophago-bronchiole fistula after esophagectomy.

Uesato M, Kono T, Akutsu Y, Murakami K, Kagaya A, Muto Y, Nakano A, Aikawa M, Tamachi T, Amagai H, Arasawa T, Muto Y, Matsubara H.

World J Gastroenterol. 2017 Jul 28;23(28):5253-5256. doi: 10.3748/wjg.v23.i28.5253.

32.

Macrophage Heterogeneity Complicates Reversal of Calcification in Cardiovascular Tissues.

Rogers MA, Aikawa M, Aikawa E.

Circ Res. 2017 Jun 23;121(1):5-7. doi: 10.1161/CIRCRESAHA.117.311219. No abstract available.

33.

Dynamin-Related Protein 1 Inhibition Attenuates Cardiovascular Calcification in the Presence of Oxidative Stress.

Rogers MA, Maldonado N, Hutcheson JD, Goettsch C, Goto S, Yamada I, Faits T, Sesaki H, Aikawa M, Aikawa E.

Circ Res. 2017 Jul 21;121(3):220-233. doi: 10.1161/CIRCRESAHA.116.310293. Epub 2017 Jun 12.

34.

Production cross sections of 169Yb and Tm isotopes in deuteron-induced reactions on 169Tm.

Saito M, Aikawa M, Komori Y, Haba H, Takács S.

Appl Radiat Isot. 2017 Jul;125:23-26. doi: 10.1016/j.apradiso.2017.04.010. Epub 2017 Apr 5.

35.

Serum Sortilin Associates With Aortic Calcification and Cardiovascular Risk in Men.

Goettsch C, Iwata H, Hutcheson JD, O'Donnell CJ, Chapurlat R, Cook NR, Aikawa M, Szulc P, Aikawa E.

Arterioscler Thromb Vasc Biol. 2017 May;37(5):1005-1011. doi: 10.1161/ATVBAHA.116.308932. Epub 2017 Mar 9.

36.

A case of aggressive solid pseudopapillary neoplasm: Comparison of clinical and pathologic features with non-aggressive cases.

Watanabe Y, Okamoto K, Okada K, Aikawa M, Koyama I, Yamaguchi H.

Pathol Int. 2017 Apr;67(4):202-207. doi: 10.1111/pin.12516. Epub 2017 Feb 16.

PMID:
28208222
37.

Unbiased and targeted mass spectrometry for the HDL proteome.

Singh SA, Aikawa M.

Curr Opin Lipidol. 2017 Feb;28(1):68-77. doi: 10.1097/MOL.0000000000000374. Review.

38.

Quantification of Calcified Particles in Human Valve Tissue Reveals Asymmetry of Calcific Aortic Valve Disease Development.

Yabusaki K, Hutcheson JD, Vyas P, Bertazzo S, Body SC, Aikawa M, Aikawa E.

Front Cardiovasc Med. 2016 Nov 4;3:44. eCollection 2016.

39.

Automation of PRM-dependent D3-Leu tracer enrichment in HDL to study the metabolism of apoA-I, LCAT and other apolipoproteins.

Lee LH, Andraski AB, Pieper B, Higashi H, Sacks FM, Aikawa M, Singh SA.

Proteomics. 2017 Jan;17(1-2). doi: 10.1002/pmic.201600085.

40.

PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation.

Iwata H, Goettsch C, Sharma A, Ricchiuto P, Goh WW, Halu A, Yamada I, Yoshida H, Hara T, Wei M, Inoue N, Fukuda D, Mojcher A, Mattson PC, Barabási AL, Boothby M, Aikawa E, Singh SA, Aikawa M.

Nat Commun. 2016 Oct 31;7:12849. doi: 10.1038/ncomms12849.

41.

Cross section measurement of alpha particle induced nuclear reactions on natural cadmium up to 52MeV.

Ditrói F, Takács S, Haba H, Komori Y, Aikawa M.

Appl Radiat Isot. 2016 Dec;118:266-276. doi: 10.1016/j.apradiso.2016.09.031. Epub 2016 Sep 30.

42.

A Comparison of the Abdominal Fat Distribution and Coronary Risk Markers in Body Mass Index-matched Subjects with and without Fatty Liver.

Shiina Y, Homma K, Ozawa H, Yoshizawa J, Kobayashi T, Igarashi M, Aikawa M, Shibata T, Homma Y.

Intern Med. 2016;55(18):2549-54. doi: 10.2169/internalmedicine.55.6731. Epub 2016 Sep 15.

43.

Delta-Like Ligand 4-Notch Signaling in Macrophage Activation.

Nakano T, Fukuda D, Koga J, Aikawa M.

Arterioscler Thromb Vasc Biol. 2016 Oct;36(10):2038-47. doi: 10.1161/ATVBAHA.116.306926. Epub 2016 Aug 25. Review.

44.

Drill needle aspiration biopsy for submucosal tumors in an experimental study.

Uesato M, Tamachi T, Hanari N, Muto Y, Kagaya A, Urahama R, Ogura Y, Suito H, Nakano A, Aikawa M, Oide T, Matsubara H.

Gastric Cancer. 2017 May;20(3):475-480. doi: 10.1007/s10120-016-0630-4. Epub 2016 Aug 16.

45.

Current Trends and Future Perspectives of State-of-the-Art Proteomics Technologies Applied to Cardiovascular Disease Research.

Singh SA, Aikawa E, Aikawa M.

Circ J. 2016 Jul 25;80(8):1674-83. doi: 10.1253/circj.CJ-16-0499. Epub 2016 Jul 14. Review.

46.

A single injection of gain-of-function mutant PCSK9 adeno-associated virus vector induces cardiovascular calcification in mice with no genetic modification.

Goettsch C, Hutcheson JD, Hagita S, Rogers MA, Creager MD, Pham T, Choi J, Mlynarchik AK, Pieper B, Kjolby M, Aikawa M, Aikawa E.

Atherosclerosis. 2016 Aug;251:109-118. doi: 10.1016/j.atherosclerosis.2016.06.011. Epub 2016 Jun 9.

47.

Endophenotype Network Models: Common Core of Complex Diseases.

Ghiassian SD, Menche J, Chasman DI, Giulianini F, Wang R, Ricchiuto P, Aikawa M, Iwata H, Müller C, Zeller T, Sharma A, Wild P, Lackner K, Singh S, Ridker PM, Blankenberg S, Barabási AL, Loscalzo J.

Sci Rep. 2016 Jun 9;6:27414. doi: 10.1038/srep27414.

48.

Macrophages in Vascular Inflammation: Origins and Functions.

Decano JL, Mattson PC, Aikawa M.

Curr Atheroscler Rep. 2016 Jun;18(6):34. doi: 10.1007/s11883-016-0585-2. Review.

PMID:
27125207
49.

Discovery of a Selective and Potent Inhibitor of Mitogen-Activated Protein Kinase-Interacting Kinases 1 and 2 (MNK1/2) Utilizing Structure-Based Drug Design.

Han W, Ding Y, Xu Y, Pfister K, Zhu S, Warne B, Doyle M, Aikawa M, Amiri P, Appleton B, Stuart DD, Fanidi A, Shafer CM.

J Med Chem. 2016 Apr 14;59(7):3034-45. doi: 10.1021/acs.jmedchem.5b01657. Epub 2016 Mar 29.

PMID:
27002243
50.

Sortilin mediates vascular calcification via its recruitment into extracellular vesicles.

Goettsch C, Hutcheson JD, Aikawa M, Iwata H, Pham T, Nykjaer A, Kjolby M, Rogers M, Michel T, Shibasaki M, Hagita S, Kramann R, Rader DJ, Libby P, Singh SA, Aikawa E.

J Clin Invest. 2016 Apr 1;126(4):1323-36. doi: 10.1172/JCI80851. Epub 2016 Mar 7.

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