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Items: 22

1.

Early epithelial signaling center governs tooth budding morphogenesis.

Ahtiainen L, Uski I, Thesleff I, Mikkola ML.

J Cell Biol. 2016 Sep 12;214(6):753-67. doi: 10.1083/jcb.201512074.

2.

Genetic Instability of Influenza pH1N1 Viruses.

Jalovaara P, Bychkov D, Ahtiainen L, Kallio-Kokko H, Valkonen M, Kantele A, Mattila P, Almusa H, Kallioniemi O, Kainov D.

Genome Announc. 2014 Oct 2;2(5). pii: e00841-14. doi: 10.1128/genomeA.00841-14.

3.

Directional cell migration, but not proliferation, drives hair placode morphogenesis.

Ahtiainen L, Lefebvre S, Lindfors PH, Renvoisé E, Shirokova V, Vartiainen MK, Thesleff I, Mikkola ML.

Dev Cell. 2014 Mar 10;28(5):588-602. doi: 10.1016/j.devcel.2014.02.003.

4.

Oncolytic adenovirus with temozolomide induces autophagy and antitumor immune responses in cancer patients.

Liikanen I, Ahtiainen L, Hirvinen ML, Bramante S, Cerullo V, Nokisalmi P, Hemminki O, Diaconu I, Pesonen S, Koski A, Kangasniemi L, Pesonen SK, Oksanen M, Laasonen L, Partanen K, Joensuu T, Zhao F, Kanerva A, Hemminki A.

Mol Ther. 2013 Jun;21(6):1212-23. doi: 10.1038/mt.2013.51. Epub 2013 Apr 2.

5.

Sox2+ stem cells contribute to all epithelial lineages of the tooth via Sfrp5+ progenitors.

Juuri E, Saito K, Ahtiainen L, Seidel K, Tummers M, Hochedlinger K, Klein OD, Thesleff I, Michon F.

Dev Cell. 2012 Aug 14;23(2):317-28. doi: 10.1016/j.devcel.2012.05.012. Epub 2012 Jul 19.

6.

Sostdc1 defines the size and number of skin appendage placodes.

Närhi K, Tummers M, Ahtiainen L, Itoh N, Thesleff I, Mikkola ML.

Dev Biol. 2012 Apr 15;364(2):149-61.

7.

Ectodysplasin regulates hormone-independent mammary ductal morphogenesis via NF-κB.

Voutilainen M, Lindfors PH, Lefebvre S, Ahtiainen L, Fliniaux I, Rysti E, Murtoniemi M, Schneider P, Schmidt-Ullrich R, Mikkola ML.

Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5744-9. doi: 10.1073/pnas.1110627109. Epub 2012 Mar 26.

8.

Macrophage metalloelastase (MME) as adjuvant for intra-tumoral injection of oncolytic adenovirus and its influence on metastases development.

Lavilla-Alonso S, Bauer MM, Abo-Ramadan U, Ristimäki A, Halavaara J, Desmond RA, Wang D, Escutenaire S, Ahtiainen L, Saksela K, Tatlisumak T, Hemminki A, Pesonen S.

Cancer Gene Ther. 2012 Feb;19(2):126-34. doi: 10.1038/cgt.2011.76. Epub 2011 Nov 18.

PMID:
22095385
9.

Radiation-induced upregulation of gene expression from adenoviral vectors mediated by DNA damage repair and regulation.

Nokisalmi P, Rajecki M, Pesonen S, Escutenaire S, Soliymani R, Tenhunen M, Ahtiainen L, Hemminki A.

Int J Radiat Oncol Biol Phys. 2012 May 1;83(1):376-84. doi: 10.1016/j.ijrobp.2011.06.1973. Epub 2011 Oct 20.

PMID:
22019240
10.

Induction of interferon pathways mediates in vivo resistance to oncolytic adenovirus.

Liikanen I, Monsurrò V, Ahtiainen L, Raki M, Hakkarainen T, Diaconu I, Escutenaire S, Hemminki O, Dias JD, Cerullo V, Kanerva A, Pesonen S, Marzioni D, Colombatti M, Hemminki A.

Mol Ther. 2011 Oct;19(10):1858-66. doi: 10.1038/mt.2011.144. Epub 2011 Jul 26.

11.

In vivo and in vitro distribution of type 5 and fiber-modified oncolytic adenoviruses in human blood compartments.

Escutenaire S, Cerullo V, Diaconu I, Ahtiainen L, Hannuksela P, Oksanen M, Haavisto E, Karioja-Kallio A, Holm SL, Kangasniemi L, Ribacka C, Kauppinen S, Joensuu T, Arstila TP, Pesonen S, Kanerva A, Hemminki A.

Ann Med. 2011 Mar;43(2):151-63. doi: 10.3109/07853890.2010.538079. Epub 2011 Jan 25.

PMID:
21261555
12.

Defects in innate immunity render breast cancer initiating cells permissive to oncolytic adenovirus.

Ahtiainen L, Mirantes C, Jahkola T, Escutenaire S, Diaconu I, Osterlund P, Kanerva A, Cerullo V, Hemminki A.

PLoS One. 2010 Nov 5;5(11):e13859. doi: 10.1371/journal.pone.0013859.

13.

Safety of glucocorticoids in cancer patients treated with oncolytic adenoviruses.

Rajecki M, Raki M, Escutenaire S, Pesonen S, Cerullo V, Helminen A, Hannuksela P, Partanen K, Laasonen L, Joensuu T, Kangasniemi L, Haavisto E, Kanerva A, Ahtiainen L, Hemminki A.

Mol Pharm. 2011 Feb 7;8(1):93-103. doi: 10.1021/mp1002174. Epub 2010 Nov 8.

PMID:
20964369
14.

Adenoviral E4orf3 and E4orf6 proteins, but not E1B55K, increase killing of cancer cells by radiotherapy in vivo.

Liikanen I, Dias JD, Nokisalmi P, Sloniecka M, Kangasniemi L, Rajecki M, Dobner T, Tenhunen M, Kanerva A, Pesonen S, Ahtiainen L, Hemminki A.

Int J Radiat Oncol Biol Phys. 2010 Nov 15;78(4):1201-9. doi: 10.1016/j.ijrobp.2010.05.037. Epub 2010 Sep 9.

PMID:
20832189
15.

Oncolytic adenovirus ICOVIR-7 in patients with advanced and refractory solid tumors.

Nokisalmi P, Pesonen S, Escutenaire S, Särkioja M, Raki M, Cerullo V, Laasonen L, Alemany R, Rojas J, Cascallo M, Guse K, Rajecki M, Kangasniemi L, Haavisto E, Karioja-Kallio A, Hannuksela P, Oksanen M, Kanerva A, Joensuu T, Ahtiainen L, Hemminki A.

Clin Cancer Res. 2010 Jun 1;16(11):3035-43. doi: 10.1158/1078-0432.CCR-09-3167. Epub 2010 May 25.

16.

Oncolytic adenovirus coding for granulocyte macrophage colony-stimulating factor induces antitumoral immunity in cancer patients.

Cerullo V, Pesonen S, Diaconu I, Escutenaire S, Arstila PT, Ugolini M, Nokisalmi P, Raki M, Laasonen L, Särkioja M, Rajecki M, Kangasniemi L, Guse K, Helminen A, Ahtiainen L, Ristimäki A, Räisänen-Sokolowski A, Haavisto E, Oksanen M, Karli E, Karioja-Kallio A, Holm SL, Kouri M, Joensuu T, Kanerva A, Hemminki A.

Cancer Res. 2010 Jun 1;70(11):4297-309. doi: 10.1158/0008-5472.CAN-09-3567. Epub 2010 May 18.

17.

Mre11 inhibition by oncolytic adenovirus associates with autophagy and underlies synergy with ionizing radiation.

Rajecki M, af Hällström T, Hakkarainen T, Nokisalmi P, Hautaniemi S, Nieminen AI, Tenhunen M, Rantanen V, Desmond RA, Chen DT, Guse K, Stenman UH, Gargini R, Kapanen M, Klefström J, Kanerva A, Pesonen S, Ahtiainen L, Hemminki A.

Int J Cancer. 2009 Nov 15;125(10):2441-9. doi: 10.1002/ijc.24608.

18.

Palmitoyl protein thioesterase 1 (Ppt1)-deficient mouse neurons show alterations in cholesterol metabolism and calcium homeostasis prior to synaptic dysfunction.

Ahtiainen L, Kolikova J, Mutka AL, Luiro K, Gentile M, Ikonen E, Khiroug L, Jalanko A, Kopra O.

Neurobiol Dis. 2007 Oct;28(1):52-64. Epub 2007 Jun 23.

PMID:
17656100
19.

Palmitoyl protein thioesterase 1 (PPT1) deficiency causes endocytic defects connected to abnormal saposin processing.

Ahtiainen L, Luiro K, Kauppi M, Tyynelä J, Kopra O, Jalanko A.

Exp Cell Res. 2006 May 15;312(9):1540-53. Epub 2006 Mar 20.

PMID:
16542649
20.

Bone marrow transplantation in young aspartylglucosaminuria mice: improved clearance of lysosomal storage in brain by using wild type as compared to heterozygote donors.

Laine M, Ahtiainen L, Rapola J, Richter J, Jalanko A.

Bone Marrow Transplant. 2004 Dec;34(11):1001-3. No abstract available.

PMID:
15489878
21.

Interconnections of CLN3, Hook1 and Rab proteins link Batten disease to defects in the endocytic pathway.

Luiro K, Yliannala K, Ahtiainen L, Maunu H, Järvelä I, Kyttälä A, Jalanko A.

Hum Mol Genet. 2004 Dec 1;13(23):3017-27. Epub 2004 Oct 7.

PMID:
15471887
22.

Palmitoyl protein thioesterase 1 is targeted to the axons in neurons.

Ahtiainen L, Van Diggelen OP, Jalanko A, Kopra O.

J Comp Neurol. 2003 Jan 13;455(3):368-77.

PMID:
12483688

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