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Doxorubicin-provoked increase of mitotic activity and concomitant drain of G0-pool in therapy-resistant BE(2)-C neuroblastoma.

Hultman I, Haeggblom L, Rognmo I, Jansson Edqvist J, Blomberg E, Ali R, Phillips L, Sandstedt B, Kogner P, Shirazi Fard S, Ährlund-Richter L.

PLoS One. 2018 Jan 17;13(1):e0190970. doi: 10.1371/journal.pone.0190970. eCollection 2018.


Loss of miR-514a-3p regulation of PEG3 activates the NF-kappa B pathway in human testicular germ cell tumors.

Özata DM, Li X, Lee L, Liu J, Warsito D, Hajeri P, Hultman I, Fotouhi O, Marklund S, Ährlund-Richter L, Juhlin CC, Larsson C, Lui WO.

Cell Death Dis. 2017 May 4;8(5):e2759. doi: 10.1038/cddis.2016.464.


Induction of sensory neurons from neuroepithelial stem cells by the ISX9 small molecule.

Ali RQ, Blomberg E, Falk A, Ährlund-Richter L, Ulfendahl M.

Am J Stem Cells. 2016 May 15;5(1):19-28. eCollection 2016.


Non-CG DNA methylation is a biomarker for assessing endodermal differentiation capacity in pluripotent stem cells.

Butcher LM, Ito M, Brimpari M, Morris TJ, Soares FA, Ährlund-Richter L, Carey N, Vallier L, Ferguson-Smith AC, Beck S.

Nat Commun. 2016 Jan 29;7:10458. doi: 10.1038/ncomms10458.


Stem Cell Therapy in Injured Vocal Folds: A Three-Month Xenograft Analysis of Human Embryonic Stem Cells.

Svensson B, Nagubothu SR, Nord C, Cedervall J, Hultman I, Ährlund-Richter L, Tolf A, Hertegård S.

Biomed Res Int. 2015;2015:754876. doi: 10.1155/2015/754876. Epub 2015 Oct 18.


Characterization of stem-like cells in mucoepidermoid tracheal paediatric tumor.

Lim ML, Ooi BN, Jungebluth P, Sjöqvist S, Hultman I, Lemon G, Gustafsson Y, Asmundsson J, Baiguera S, Douagi I, Gilevich I, Popova A, Haag JC, Rodríguez AB, Lim J, Liedén A, Nordenskjöld M, Alici E, Baker D, Unger C, Luedde T, Vassiliev I, Inzunza J, Ahrlund-Richter L, Macchiarini P.

PLoS One. 2014 Sep 17;9(9):e107712. doi: 10.1371/journal.pone.0107712. eCollection 2014.


Experimental teratoma: at the crossroad of fetal- and onco-development.

Hultman I, Björk L, Blomberg E, Sandstedt B, Ahrlund-Richter L.

Semin Cancer Biol. 2014 Dec;29:75-9. doi: 10.1016/j.semcancer.2014.08.005. Epub 2014 Aug 19. Review.


Oncofetal signaling as a target for cancer therapy.

Ahrlund-Richter L, Hendrix MJ.

Semin Cancer Biol. 2014 Dec;29:1-2. doi: 10.1016/j.semcancer.2014.08.001. Epub 2014 Aug 8. No abstract available.


Glial origin of mesenchymal stem cells in a tooth model system.

Kaukua N, Shahidi MK, Konstantinidou C, Dyachuk V, Kaucka M, Furlan A, An Z, Wang L, Hultman I, Ahrlund-Richter L, Blom H, Brismar H, Lopes NA, Pachnis V, Suter U, Clevers H, Thesleff I, Sharpe P, Ernfors P, Fried K, Adameyko I.

Nature. 2014 Sep 25;513(7519):551-4. doi: 10.1038/nature13536. Epub 2014 Jul 27.


An expression signature at diagnosis to estimate prostate cancer patients' overall survival.

Peng Z, Skoog L, Hellborg H, Jonstam G, Wingmo IL, Hjälm-Eriksson M, Harmenberg U, Cedermark GC, Andersson K, Ahrlund-Richter L, Pramana S, Pawitan Y, Nistér M, Nilsson S, Li C.

Prostate Cancer Prostatic Dis. 2014 Mar;17(1):81-90. doi: 10.1038/pcan.2013.57. Epub 2014 Jan 7.


Tropism of the in situ growth from biopsies of childhood neuroectodermal tumors following transplantation into experimental teratoma.

Jamil S, Hultman I, Cedervall J, Ali RQ, Fuchs G, Gustavsson B, Asmundsson J, Sandstedt B, Kogner P, Ährlund-Richter L.

Int J Cancer. 2014 Apr 1;134(7):1630-7. doi: 10.1002/ijc.28498. Epub 2013 Oct 17.


Neuroblastoma cells injected into experimental mature teratoma reveal a tropism for embryonic loose mesenchyme.

Jamil S, Cedervall J, Hultman I, Ali R, Margaryan NV, Rasmuson A, Johnsen JI, Sveinbjörnsson B, Dalianis T, Kanter L, Orrego A, Strizzi L, Hendrix MJ, Sandstedt B, Kogner P, Ahrlund-Richter L.

Int J Oncol. 2013 Sep;43(3):831-8. doi: 10.3892/ijo.2013.2014. Epub 2013 Jul 12.


Nodal expression and detection in cancer: experience and challenges.

Strizzi L, Hardy KM, Kirschmann DA, Ahrlund-Richter L, Hendrix MJ.

Cancer Res. 2012 Apr 15;72(8):1915-20. doi: 10.1158/0008-5472.CAN-11-3419. Review.


Early events in xenograft development from the human embryonic stem cell line HS181--resemblance with an initial multiple epiblast formation.

Gertow K, Cedervall J, Jamil S, Ali R, Imreh MP, Gulyas M, Sandstedt B, Ahrlund-Richter L.

PLoS One. 2011;6(11):e27741. doi: 10.1371/journal.pone.0027741. Epub 2011 Nov 30.


Concise review: Cord blood banking, transplantation and induced pluripotent stem cell: success and opportunities.

Rao M, Ahrlund-Richter L, Kaufman DS.

Stem Cells. 2012 Jan;30(1):55-60. doi: 10.1002/stem.770. Review.


Injection of human mesenchymal stem cells improves healing of vocal folds after scar excision--a xenograft analysis.

Svensson B, Nagubothu SR, Cedervall J, Chan RW, Le Blanc K, Kimura M, Ährlund-Richter L, Tolf A, Hertegård S.

Laryngoscope. 2011 Oct;121(10):2185-90. doi: 10.1002/lary.22143. Epub 2011 Sep 6.


Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells.

Rashid ST, Corbineau S, Hannan N, Marciniak SJ, Miranda E, Alexander G, Huang-Doran I, Griffin J, Ahrlund-Richter L, Skepper J, Semple R, Weber A, Lomas DA, Vallier L.

J Clin Invest. 2010 Sep;120(9):3127-36. doi: 10.1172/JCI43122. Epub 2010 Aug 25.


Injection of human mesenchymal stem cells improves healing of scarred vocal folds: analysis using a xenograft model.

Svensson B, Nagubothu RS, Cedervall J, Le Blanc K, Ahrlund-Richter L, Tolf A, Hertegård S.

Laryngoscope. 2010 Jul;120(7):1370-5. doi: 10.1002/lary.20926.


Lineage-specific promoter DNA methylation patterns segregate adult progenitor cell types.

Sørensen AL, Timoskainen S, West FD, Vekterud K, Boquest AC, Ahrlund-Richter L, Stice SL, Collas P.

Stem Cells Dev. 2010 Aug;19(8):1257-66. doi: 10.1089/scd.2009.0309.


Signaling pathways controlling pluripotency and early cell fate decisions of human induced pluripotent stem cells.

Vallier L, Touboul T, Brown S, Cho C, Bilican B, Alexander M, Cedervall J, Chandran S, Ahrlund-Richter L, Weber A, Pedersen RA.

Stem Cells. 2009 Nov;27(11):2655-66. doi: 10.1002/stem.199.


Melatonin promotes the cumulus-oocyte complexes quality of vitrified-thawed murine ovaries; with increased mean number of follicles survival and ovary size following heterotopic transplantation.

Hemadi M, Abolhassani F, Akbari M, Sobhani A, Pasbakhsh P, Ahrlund-Richter L, Modaresi MH, Salehnia M.

Eur J Pharmacol. 2009 Sep 15;618(1-3):84-90. doi: 10.1016/j.ejphar.2009.07.018. Epub 2009 Jul 19.


Species-specific in vivo engraftment of the human BL melanoma cell line results in an invasive dedifferentiated phenotype not present in xenografts.

Cedervall J, Jamil S, Prasmickaite L, Cheng Y, Eskandarpour M, Hansson J, Maelandsmo GM, Ringborg U, Gulyas M, Zhen HS, Kanter L, Ahrlund-Richter L.

Cancer Res. 2009 May 1;69(9):3746-54. doi: 10.1158/0008-5472.CAN-08-3746. Epub 2009 Apr 21.


Isolation and production of cells suitable for human therapy: challenges ahead.

Ahrlund-Richter L, De Luca M, Marshak DR, Munsie M, Veiga A, Rao M.

Cell Stem Cell. 2009 Jan 9;4(1):20-6. doi: 10.1016/j.stem.2008.11.012. Epub 2008 Dec 8.


New ISSCR guidelines underscore major principles for responsible translational stem cell research.

Hyun I, Lindvall O, Ahrlund-Richter L, Cattaneo E, Cavazzana-Calvo M, Cossu G, De Luca M, Fox IJ, Gerstle C, Goldstein RA, Hermerén G, High KA, Kim HO, Lee HP, Levy-Lahad E, Li L, Lo B, Marshak DR, McNab A, Munsie M, Nakauchi H, Rao M, Rooke HM, Valles CS, Srivastava A, Sugarman J, Taylor PL, Veiga A, Wong AL, Zoloth L, Daley GQ.

Cell Stem Cell. 2008 Dec 4;3(6):607-9. doi: 10.1016/j.stem.2008.11.009. Review.


Dynamics of gene expression during bone matrix formation in osteogenic cultures derived from human embryonic stem cells in vitro.

Kärner E, Bäckesjö CM, Cedervall J, Sugars RV, Ahrlund-Richter L, Wendel M.

Biochim Biophys Acta. 2009 Feb;1790(2):110-8. doi: 10.1016/j.bbagen.2008.10.004. Epub 2008 Oct 25.


Differentiation of human embryonic stem cells into osteogenic or hematopoietic lineages: a dose-dependent effect of osterix over-expression.

Kärner E, Unger C, Cerny R, Ahrlund-Richter L, Ganss B, Dilber MS, Wendel M.

J Cell Physiol. 2009 Feb;218(2):323-33. doi: 10.1002/jcp.21605.


Isolation of human embryonic stem cell-derived teratomas for the assessment of pluripotency.

Gertow K, Przyborski S, Loring JF, Auerbach JM, Epifano O, Otonkoski T, Damjanov I, Ahrlund-Richter L.

Curr Protoc Stem Cell Biol. 2007 Oct;Chapter 1:Unit1B.4. doi: 10.1002/9780470151808.sc01b04s3.


Lentiviral-mediated HoxB4 expression in human embryonic stem cells initiates early hematopoiesis in a dose-dependent manner but does not promote myeloid differentiation.

Unger C, Kärner E, Treschow A, Stellan B, Felldin U, Concha H, Wendel M, Hovatta O, Aints A, Ahrlund-Richter L, Dilber MS.

Stem Cells. 2008 Oct;26(10):2455-66. doi: 10.1634/stemcells.2007-0876. Epub 2008 Jul 10.


Injection of embryonic stem cells into scarred rabbit vocal folds enhances healing and improves viscoelasticity: short-term results.

Cedervall J, Ahrlund-Richter L, Svensson B, Forsgren K, Maurer FH, Vidovska D, Hertegård S.

Laryngoscope. 2007 Nov;117(11):2075-81.


Derivation of pluripotent epiblast stem cells from mammalian embryos.

Brons IG, Smithers LE, Trotter MW, Rugg-Gunn P, Sun B, Chuva de Sousa Lopes SM, Howlett SK, Clarkson A, Ahrlund-Richter L, Pedersen RA, Vallier L.

Nature. 2007 Jul 12;448(7150):191-5. Epub 2007 Jun 27.


Characterization of human embryonic stem cell lines by the International Stem Cell Initiative.

International Stem Cell Initiative, Adewumi O, Aflatoonian B, Ahrlund-Richter L, Amit M, Andrews PW, Beighton G, Bello PA, Benvenisty N, Berry LS, Bevan S, Blum B, Brooking J, Chen KG, Choo AB, Churchill GA, Corbel M, Damjanov I, Draper JS, Dvorak P, Emanuelsson K, Fleck RA, Ford A, Gertow K, Gertsenstein M, Gokhale PJ, Hamilton RS, Hampl A, Healy LE, Hovatta O, Hyllner J, Imreh MP, Itskovitz-Eldor J, Jackson J, Johnson JL, Jones M, Kee K, King BL, Knowles BB, Lako M, Lebrin F, Mallon BS, Manning D, Mayshar Y, McKay RD, Michalska AE, Mikkola M, Mileikovsky M, Minger SL, Moore HD, Mummery CL, Nagy A, Nakatsuji N, O'Brien CM, Oh SK, Olsson C, Otonkoski T, Park KY, Passier R, Patel H, Patel M, Pedersen R, Pera MF, Piekarczyk MS, Pera RA, Reubinoff BE, Robins AJ, Rossant J, Rugg-Gunn P, Schulz TC, Semb H, Sherrer ES, Siemen H, Stacey GN, Stojkovic M, Suemori H, Szatkiewicz J, Turetsky T, Tuuri T, van den Brink S, Vintersten K, Vuoristo S, Ward D, Weaver TA, Young LA, Zhang W.

Nat Biotechnol. 2007 Jul;25(7):803-16. Epub 2007 Jun 17.


Ethics. The ISSCR guidelines for human embryonic stem cell research.

Daley GQ, Ahrlund Richter L, Auerbach JM, Benvenisty N, Charo RA, Chen G, Deng HK, Goldstein LS, Hudson KL, Hyun I, Junn SC, Love J, Lee EH, McLaren A, Mummery CL, Nakatsuji N, Racowsky C, Rooke H, Rossant J, Schöler HR, Solbakk JH, Taylor P, Trounson AO, Weissman IL, Wilmut I, Yu J, Zoloth L.

Science. 2007 Feb 2;315(5812):603-4. No abstract available.


Bone matrix formation in osteogenic cultures derived from human embryonic stem cells in vitro.

Kärner E, Unger C, Sloan AJ, Ahrlund-Richter L, Sugars RV, Wendel M.

Stem Cells Dev. 2007 Feb;16(1):39-52.


Trisomy 12 in HESC leads to no selective in vivo growth advantage in teratomas, but induces an increased abundance of renal development.

Gertow K, Cedervall J, Unger C, Szöke K, Blennow E, Imreh MP, Ahrlund-Richter L.

J Cell Biochem. 2007 Apr 15;100(6):1518-25.


Horse embryonic stem cell lines from the proliferation of inner cell mass cells.

Li X, Zhou SG, Imreh MP, Ahrlund-Richter L, Allen WR.

Stem Cells Dev. 2006 Aug;15(4):523-31.


Viscoelastic and histologic properties in scarred rabbit vocal folds after mesenchymal stem cell injection.

Hertegård S, Cedervall J, Svensson B, Forsberg K, Maurer FH, Vidovska D, Olivius P, Ahrlund-Richter L, Le Blanc K.

Laryngoscope. 2006 Jul;116(7):1248-54.


In vitro culture conditions favoring selection of chromosomal abnormalities in human ES cells.

Imreh MP, Gertow K, Cedervall J, Unger C, Holmberg K, Szöke K, Csöregh L, Fried G, Dilber S, Blennow E, Ahrlund-Richter L.

J Cell Biochem. 2006 Oct 1;99(2):508-16.


Germfree status of mice obtained by embryo transfer in an isolator environment.

Inzunza J, Midtvedt T, Fartoo M, Norin E, Osterlund E, Persson AK, Ahrlund-Richter L.

Lab Anim. 2005 Oct;39(4):421-7.


Derivation of human embryonic stem cell lines in serum replacement medium using postnatal human fibroblasts as feeder cells.

Inzunza J, Gertow K, Strömberg MA, Matilainen E, Blennow E, Skottman H, Wolbank S, Ahrlund-Richter L, Hovatta O.

Stem Cells. 2005 Apr;23(4):544-9.


Organized development from human embryonic stem cells after injection into immunodeficient mice.

Gertow K, Wolbank S, Rozell B, Sugars R, Andäng M, Parish CL, Imreh MP, Wendel M, Ahrlund-Richter L.

Stem Cells Dev. 2004 Aug;13(4):421-35.


Culture and expansion of the human embryonic stem cell line HS181, evaluated in a double-color system.

Imreh MP, Wolbank S, Unger C, Gertow K, Aints A, Szeles A, Imreh S, Hovatta O, Fried G, Dilber S, Ahrlund-Richter L.

Stem Cells Dev. 2004 Aug;13(4):337-43.


Efficacy and mode of action of hammerhead and hairpin ribozymes against various HIV-1 target sites.

Hotchkiss G, Maijgren-Steffensson C, Ahrlund-Richter L.

Mol Ther. 2004 Jul;10(1):172-80.


Cis-cleavage affects hammerhead and hairpin ribozyme steady-state levels differently and has strong impact on trans-targeting efficiency.

Andäng M, Maijgren-Steffensson C, Hinkula J, Ahrlund-Richter L.

Oligonucleotides. 2004 Spring;14(1):11-21.


A culture system using human foreskin fibroblasts as feeder cells allows production of human embryonic stem cells.

Hovatta O, Mikkola M, Gertow K, Strömberg AM, Inzunza J, Hreinsson J, Rozell B, Blennow E, Andäng M, Ahrlund-Richter L.

Hum Reprod. 2003 Jul;18(7):1404-9.


Single cell CGH analysis reveals a high degree of mosaicism in human embryos from patients with balanced structural chromosome aberrations.

Malmgren H, Sahlén S, Inzunza J, Aho M, Rosenlund B, Fridström M, Hovatta O, Ahrlund-Richter L, Nordenskjöld M, Blennow E.

Mol Hum Reprod. 2002 May;8(5):502-10.


[Ethical aspects of stem cell research. Legislation and guidelines in Europe].

Hovatta O, Ahrlund-Richter L.

Lakartidningen. 2001 Aug 22;98(34):3515-9. Swedish.


Clinical outcome of treatment cycles using preimplantation genetic diagnosis for structural chromosomal abnormalities.

Fridström M, Ahrlund-Richter L, Iwarsson E, Malmgren H, Inzunza J, Rosenlund B, Sjöblom P, Nordenskjöld M, Blennow E, Hovatta O.

Prenat Diagn. 2001 Sep;21(9):781-7.


Smaller amounts of antiretroviral drugs are needed when combined with an active ribozyme against HIV-1.

Maijgren-Steffensson C, Sönnerborg A, Vahlne A, Britton S, Larsson S, Ahrlund-Richter L.

Mol Ther. 2001 Apr;3(4):531-5.


Highly abnormal cleavage divisions in preimplantation embryos from translocation carriers.

Iwarsson E, Malmgren H, Inzunza J, Ahrlund-Richter L, Sjöblom P, Rosenlund B, Fridström M, Hovatta O, Nordenskjöld M, Blennow E.

Prenat Diagn. 2000 Dec;20(13):1038-47.


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