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Longitudinal evaluation of Tau-P301L transgenic mice reveals no cognitive impairments at 17 months of age.

Kent BA, Heath CJ, Kim CH, Ahrens R, Fraser PE, St George-Hyslop P, Bussey TJ, Saksida LM.

Brain Behav. 2017 Dec 18;8(1):e00896. doi: 10.1002/brb3.896. eCollection 2018 Jan.


Tau ablation in mice leads to pancreatic β cell dysfunction and glucose intolerance.

Wijesekara N, Gonçalves RA, Ahrens R, De Felice FG, Fraser PE.

FASEB J. 2018 Jun;32(6):3166-3173. doi: 10.1096/fj.201701352. Epub 2018 Jan 18.


Optional part-time and longer GP training modules in GP practices associated with more trainees becoming GPs - a cohort study in Switzerland.

Studerus L, Ahrens R, Häuptle C, Goeldlin A, Streit S.

BMC Fam Pract. 2018 Jan 5;19(1):5. doi: 10.1186/s12875-017-0706-1.


Effect of Study Design on Sample Size in Studies Intended to Evaluate Bioequivalence of Inhaled Short-Acting β-Agonist Formulations.

Zeng Y, Singh S, Wang K, Ahrens RC.

J Clin Pharmacol. 2018 Apr;58(4):457-465. doi: 10.1002/jcph.1045. Epub 2017 Dec 27.


Airway microbiota across age and disease spectrum in cystic fibrosis.

Zemanick ET, Wagner BD, Robertson CE, Ahrens RC, Chmiel JF, Clancy JP, Gibson RL, Harris WT, Kurland G, Laguna TA, McColley SA, McCoy K, Retsch-Bogart G, Sobush KT, Zeitlin PL, Stevens MJ, Accurso FJ, Sagel SD, Harris JK.

Eur Respir J. 2017 Nov 16;50(5). pii: 1700832. doi: 10.1183/13993003.00832-2017. Print 2017 Nov.


Amyloid-β and islet amyloid pathologies link Alzheimer's disease and type 2 diabetes in a transgenic model.

Wijesekara N, Ahrens R, Sabale M, Wu L, Ha K, Verdile G, Fraser PE.

FASEB J. 2017 Dec;31(12):5409-5418. doi: 10.1096/fj.201700431R. Epub 2017 Aug 14.


Integration of digital microfluidics with whispering-gallery mode sensors for label-free detection of biomolecules.

Wondimu SF, von der Ecken S, Ahrens R, Freude W, Guber AE, Koos C.

Lab Chip. 2017 May 16;17(10):1740-1748. doi: 10.1039/c6lc01556e.


Time-resolved NMR metabolomics of plant cells based on a microfluidic chip.

Maisch J, Kreppenhofer K, Büchler S, Merle C, Sobich S, Görling B, Luy B, Ahrens R, Guber AE, Nick P.

J Plant Physiol. 2016 Aug 1;200:28-34. doi: 10.1016/j.jplph.2016.06.004. Epub 2016 Jun 10.


Safety and Efficacy of a Novel Microbial Lipase in Patients with Exocrine Pancreatic Insufficiency due to Cystic Fibrosis: A Randomized Controlled Clinical Trial.

Heubi JE, Schaeffer D, Ahrens RC, Sollo N, Strausbaugh S, Graff G, Jain R, Witte S, Forssmann K.

J Pediatr. 2016 Sep;176:156-161.e1. doi: 10.1016/j.jpeds.2016.05.049. Epub 2016 Jun 11.


Loss of IL-4Rα-mediated PI3K signaling accelerates the progression of IgE/mast cell-mediated reactions.

Sledd J, Wu D, Ahrens R, Lee J, Waggoner L, Tsai YT, Wang YH, Hogan SP.

Immun Inflamm Dis. 2015 Sep 17;3(4):420-30. doi: 10.1002/iid3.80. eCollection 2015 Dec.


Bioassay of salmeterol in children using methacholine challenge with impulse oscillometry.

Mondal P, Baumstein S, Prabhakaran S, Abu-Hasan M, Zeng Y, Singh S, Wang K, Ahrens RC, Hendeles L.

Pediatr Pulmonol. 2016 Jun;51(6):570-5. doi: 10.1002/ppul.23345. Epub 2015 Nov 17.


Islet amyloid inhibitors improve glucose homeostasis in a transgenic mouse model of type 2 diabetes.

Wijesekara N, Ahrens R, Wu L, Ha K, Liu Y, Wheeler MB, Fraser PE.

Diabetes Obes Metab. 2015 Oct;17(10):1003-6. doi: 10.1111/dom.12529. Epub 2015 Aug 19.


[Personnel resources for psychiatric institutions. Needs assessment exemplified by the nursing profession in Germany].

Löhr M, Sauter D, Nienaber A, Heuft G, Ahrens R, Oppermann G, Heinz A, Schulz M; Employees of the AG structure and quality of DFPP BFLK.

Nervenarzt. 2015 Jul;86(7):857-65. doi: 10.1007/s00115-015-4356-z. German.


Efficacy response in CF patients treated with ivacaftor: post-hoc analysis.

Konstan MW, Plant BJ, Elborn JS, Rodriguez S, Munck A, Ahrens R, Johnson C.

Pediatr Pulmonol. 2015 May;50(5):447-55. doi: 10.1002/ppul.23173. Epub 2015 Mar 9.


Stock enhancement to address multiple recreational fisheries objectives: an integrated model applied to red drum Sciaenops ocellatus in Florida.

Camp EV, Lorenzen K, Ahrens RN, Allen MS.

J Fish Biol. 2014 Dec;85(6):1868-89. doi: 10.1111/jfb.12548.


Reply to the letter to the editor of K. Walsh.

Ahrens R, Barth J, Schaufelberger M.

Swiss Med Wkly. 2014 Sep 25;144:w13994. doi: 10.4414/smw.2014.13994. eCollection 2014. No abstract available.


Nonprescription racemic epinephrine for asthma.

Mondal P, Kandala B, Ahrens R, Chesrown SE, Hendeles L.

J Allergy Clin Immunol Pract. 2014 Sep-Oct;2(5):575-8. doi: 10.1016/j.jaip.2014.02.014. Epub 2014 Apr 18.


1α,25-Dihydroxyvitamin D3 reduces cerebral amyloid-β accumulation and improves cognition in mouse models of Alzheimer's disease.

Durk MR, Han K, Chow EC, Ahrens R, Henderson JT, Fraser PE, Pang KS.

J Neurosci. 2014 May 21;34(21):7091-101. doi: 10.1523/JNEUROSCI.2711-13.2014.


Consequences of insecurity in emergency telephone consultations: an experimental study in medical students.

Barth J, Ahrens R, Schaufelberger M.

Swiss Med Wkly. 2014 Mar 28;144:w13919. doi: 10.4414/smw.2014.13919. eCollection 2014.


Fabrication of polymeric microfluidic devices with tunable wetting behavior for biomedical applications.

Steidle NE, Schneider M, Ahrens R, Worgull M, Guber AE.

Conf Proc IEEE Eng Med Biol Soc. 2013;2013:6659-62. doi: 10.1109/EMBC.2013.6611083.


CD14+CD33+ myeloid cell-CCL11-eosinophil signature in ulcerative colitis.

Lampinen M, Waddell A, Ahrens R, Carlson M, Hogan SP.

J Leukoc Biol. 2013 Nov;94(5):1061-70. doi: 10.1189/jlb.1212640. Epub 2013 Jul 31.


Efficacy and safety of ivacaftor in patients aged 6 to 11 years with cystic fibrosis with a G551D mutation.

Davies JC, Wainwright CE, Canny GJ, Chilvers MA, Howenstine MS, Munck A, Mainz JG, Rodriguez S, Li H, Yen K, Ordoñez CL, Ahrens R; VX08-770-103 (ENVISION) Study Group.

Am J Respir Crit Care Med. 2013 Jun 1;187(11):1219-25. doi: 10.1164/rccm.201301-0153OC.


Intestinal CCL11 and eosinophilic inflammation is regulated by myeloid cell-specific RelA/p65 in mice.

Waddell A, Ahrens R, Tsai YT, Sherrill JD, Denson LA, Steinbrecher KA, Hogan SP.

J Immunol. 2013 May 1;190(9):4773-85. doi: 10.4049/jimmunol.1200057. Epub 2013 Apr 5.


Chymase-mediated intestinal epithelial permeability is regulated by a protease-activating receptor/matrix metalloproteinase-2-dependent mechanism.

Groschwitz KR, Wu D, Osterfeld H, Ahrens R, Hogan SP.

Am J Physiol Gastrointest Liver Physiol. 2013 Mar 1;304(5):G479-89. doi: 10.1152/ajpgi.00186.2012. Epub 2013 Jan 10.


Diffusion- and convection-based activation of Wnt/β-catenin signaling in a gradient generating microfluidic chip.

Kim C, Kreppenhofer K, Kashef J, Gradl D, Herrmann D, Schneider M, Ahrens R, Guber A, Wedlich D.

Lab Chip. 2012 Dec 21;12(24):5186-94. doi: 10.1039/c2lc40172j.


Equivalence considerations for orally inhaled products for local action-ISAM/IPAC-RS European Workshop report.

Evans C, Cipolla D, Chesworth T, Agurell E, Ahrens R, Conner D, Dissanayake S, Dolovich M, Doub W, Fuglsang A, García Arieta A, Golden M, Hermann R, Hochhaus G, Holmes S, Lafferty P, Lyapustina S, Nair P, O'Connor D, Parkins D, Peterson I, Reisner C, Sandell D, Singh GJ, Weda M, Watson P.

J Aerosol Med Pulm Drug Deliv. 2012 Jun;25(3):117-39. doi: 10.1089/jamp.2011.0968. Epub 2012 Mar 13.


Intestinal mast cell levels control severity of oral antigen-induced anaphylaxis in mice.

Ahrens R, Osterfeld H, Wu D, Chen CY, Arumugam M, Groschwitz K, Strait R, Wang YH, Finkelman FD, Hogan SP.

Am J Pathol. 2012 Apr;180(4):1535-46. doi: 10.1016/j.ajpath.2011.12.036. Epub 2012 Feb 7.


Long-term intersession variability for single-breath diffusing capacity.

Hegewald MJ, Jensen RL, Teeter JG, Wise RA, Riese RJ, England RD, Ahrens RC, Crapo RO, MacIntyre NR.

Respiration. 2012;84(5):377-84. doi: 10.1159/000334699. Epub 2011 Dec 31.


Microstructuring of multiwell plates for three-dimensional cell culture applications by ultrasonic embossing.

Altmann B, Ahrens R, Welle A, Dinglreiter H, Schneider M, Schober A.

Biomed Microdevices. 2012 Apr;14(2):291-301. doi: 10.1007/s10544-011-9605-8.


Methacholine challenge as a clinical bioassay of pulmonary delivery of a long-acting β₂-adrenergic agonist.

Prabhakaran S, Shuster J, Ahrens R, Hendeles L.

Pharmacotherapy. 2011 May;31(5):449-57. doi: 10.1592/phco.31.5.449.


Colonic eosinophilic inflammation in experimental colitis is mediated by Ly6C(high) CCR2(+) inflammatory monocyte/macrophage-derived CCL11.

Waddell A, Ahrens R, Steinbrecher K, Donovan B, Rothenberg ME, Munitz A, Hogan SP.

J Immunol. 2011 May 15;186(10):5993-6003. doi: 10.4049/jimmunol.1003844. Epub 2011 Apr 15.


The adult mouse and human pancreas contain rare multipotent stem cells that express insulin.

Smukler SR, Arntfield ME, Razavi R, Bikopoulos G, Karpowicz P, Seaberg R, Dai F, Lee S, Ahrens R, Fraser PE, Wheeler MB, van der Kooy D.

Cell Stem Cell. 2011 Mar 4;8(3):281-93. doi: 10.1016/j.stem.2011.01.015.


Interleukin-13 (IL-13)/IL-13 receptor alpha1 (IL-13Ralpha1) signaling regulates intestinal epithelial cystic fibrosis transmembrane conductance regulator channel-dependent Cl- secretion.

Wu D, Ahrens R, Osterfeld H, Noah TK, Groschwitz K, Foster PS, Steinbrecher KA, Rothenberg ME, Shroyer NF, Matthaei KI, Finkelman FD, Hogan SP.

J Biol Chem. 2011 Apr 15;286(15):13357-69. doi: 10.1074/jbc.M110.214965. Epub 2011 Feb 8.


Increased susceptibility of 129SvEvBrd mice to IgE-Mast cell mediated anaphylaxis.

Arumugam M, Ahrens R, Osterfeld H, Kottyan LC, Shang X, Maclennan JA, Zimmermann N, Zheng Y, Finkelman FD, Hogan SP.

BMC Immunol. 2011 Feb 3;12:14. doi: 10.1186/1471-2172-12-14.


Efficacy and Safety of a New Formulation of Pancrelipase (Ultrase MT20) in the Treatment of Malabsorption in Exocrine Pancreatic Insufficiency in Cystic Fibrosis.

Konstan MW, Liou TG, Strausbaugh SD, Ahrens R, Kanga JF, Graff GR, Moffett K, Millard SL, Nasr SZ, Siméon E, Spénard J, Grondin J.

Gastroenterol Res Pract. 2010;2010:898193. doi: 10.1155/2010/898193. Epub 2010 Dec 8.


Randomized trial of biofilm testing to select antibiotics for cystic fibrosis airway infection.

Moskowitz SM, Emerson JC, McNamara S, Shell RD, Orenstein DM, Rosenbluth D, Katz MF, Ahrens R, Hornick D, Joseph PM, Gibson RL, Aitken ML, Benton WW, Burns JL.

Pediatr Pulmonol. 2011 Feb;46(2):184-92. doi: 10.1002/ppul.21350. Epub 2010 Oct 20.


Standing genetic variation and compensatory evolution in transgenic organisms: a growth-enhanced salmon simulation.

Ahrens RN, Devlin RH.

Transgenic Res. 2011 Jun;20(3):583-97. doi: 10.1007/s11248-010-9443-0. Epub 2010 Sep 29.


Paired immunoglobulin-like receptor B (PIR-B) negatively regulates macrophage activation in experimental colitis.

Munitz A, Cole ET, Beichler A, Groschwitz K, Ahrens R, Steinbrecher K, Willson T, Han X, Denson L, Rothenberg ME, Hogan SP.

Gastroenterology. 2010 Aug;139(2):530-41. doi: 10.1053/j.gastro.2010.04.006. Epub 2010 Apr 14.


Differential roles for the IL-9/IL-9 receptor alpha-chain pathway in systemic and oral antigen-induced anaphylaxis.

Osterfeld H, Ahrens R, Strait R, Finkelman FD, Renauld JC, Hogan SP.

J Allergy Clin Immunol. 2010 Feb;125(2):469-476.e2. doi: 10.1016/j.jaci.2009.09.054.


Demonstrating Bioequivalence of Locally Acting Orally Inhaled Drug Products (OIPs): Workshop Summary Report.

Adams WP, Ahrens RC, Chen ML, Christopher D, Chowdhury BA, Conner DP, Dalby R, Fitzgerald K, Hendeles L, Hickey AJ, Hochhaus G, Laube BL, Lucas P, Lee SL, Lyapustina S, Li B, O'Connor D, Parikh N, Parkins DA, Peri P, Pitcairn GR, Riebe M, Roy P, Shah T, Singh GJ, Sharp SS, Suman JD, Weda M, Woodcock J, Yu L.

J Aerosol Med Pulm Drug Deliv. 2010 Feb;23(1):1-29. doi: 10.1089/jamp.2009.0803.


Mast cells regulate homeostatic intestinal epithelial migration and barrier function by a chymase/Mcpt4-dependent mechanism.

Groschwitz KR, Ahrens R, Osterfeld H, Gurish MF, Han X, Abrink M, Finkelman FD, Pejler G, Hogan SP.

Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22381-6. doi: 10.1073/pnas.0906372106. Epub 2009 Dec 16.


Resistin-like molecule alpha decreases glucose tolerance during intestinal inflammation.

Munitz A, Seidu L, Cole ET, Ahrens R, Hogan SP, Rothenberg ME.

J Immunol. 2009 Feb 15;182(4):2357-63. doi: 10.4049/jimmunol.0803130.


Resistin-like molecule alpha enhances myeloid cell activation and promotes colitis.

Munitz A, Waddell A, Seidu L, Cole ET, Ahrens R, Hogan SP, Rothenberg ME.

J Allergy Clin Immunol. 2008 Dec;122(6):1200-1207.e1. doi: 10.1016/j.jaci.2008.10.017.


Intestinal macrophage/epithelial cell-derived CCL11/eotaxin-1 mediates eosinophil recruitment and function in pediatric ulcerative colitis.

Ahrens R, Waddell A, Seidu L, Blanchard C, Carey R, Forbes E, Lampinen M, Wilson T, Cohen E, Stringer K, Ballard E, Munitz A, Xu H, Lee N, Lee JJ, Rothenberg ME, Denson L, Hogan SP.

J Immunol. 2008 Nov 15;181(10):7390-9.


Single voxel magnetic resonance spectroscopy at 3 Tesla in a memory disorders clinic: early right hippocampal NAA/Cr loss in mildly impaired subjects.

Caserta MT, Ragin A, Hermida AP, Ahrens RJ, Wise L.

Psychiatry Res. 2008 Nov 30;164(2):154-9. doi: 10.1016/j.pscychresns.2008.04.002. Epub 2008 Oct 19.


Intersession variability in single-breath diffusing capacity in diabetics without overt lung disease.

Drummond MB, Schwartz PF, Duggan WT, Teeter JG, Riese RJ, Ahrens RC, Crapo RO, England RD, Macintyre NR, Jensen RL, Wise RA.

Am J Respir Crit Care Med. 2008 Aug 1;178(3):225-32. doi: 10.1164/rccm.200801-090OC. Epub 2008 May 8.


IL-9- and mast cell-mediated intestinal permeability predisposes to oral antigen hypersensitivity.

Forbes EE, Groschwitz K, Abonia JP, Brandt EB, Cohen E, Blanchard C, Ahrens R, Seidu L, McKenzie A, Strait R, Finkelman FD, Foster PS, Matthaei KI, Rothenberg ME, Hogan SP.

J Exp Med. 2008 Apr 14;205(4):897-913. doi: 10.1084/jem.20071046. Epub 2008 Mar 31.


Standardization of the single-breath diffusing capacity in a multicenter clinical trial.

Wise RA, Teeter JG, Jensen RL, England RD, Schwartz PF, Giles DR, Ahrens RC, MacIntyre NR, Riese RJ, Crapo RO.

Chest. 2007 Oct;132(4):1191-7. Epub 2007 Sep 21.


Resistin-like molecule beta regulates innate colonic function: barrier integrity and inflammation susceptibility.

Hogan SP, Seidu L, Blanchard C, Groschwitz K, Mishra A, Karow ML, Ahrens R, Artis D, Murphy AJ, Valenzuela DM, Yancopoulos GD, Rothenberg ME.

J Allergy Clin Immunol. 2006 Jul;118(1):257-68.

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