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Development and Application of the Metalloprotease Activity Multiplexed Bead-Based Immunoassay (MAMBI).

Ahrens CC, Chiswick EL, Ravindra KC, Miller MA, Ramseier JY, Isaacson KB, Lauffenburger DA, Griffith LG.

Biochemistry. 2019 Sep 24;58(38):3938-3942. doi: 10.1021/acs.biochem.9b00584. Epub 2019 Sep 9.


Adaptive variation for growth and resistance to a novel pathogen along climatic gradients in a foundation tree.

Ahrens CW, Mazanec RA, Paap T, Ruthrof KX, Challis A, Hardy G, Byrne M, Tissue DT, Rymer PD.

Evol Appl. 2019 Apr 15;12(6):1178-1190. doi: 10.1111/eva.12796. eCollection 2019 Jun.


Long-read based de novo assembly of low-complexity metagenome samples results in finished genomes and reveals insights into strain diversity and an active phage system.

Somerville V, Lutz S, Schmid M, Frei D, Moser A, Irmler S, Frey JE, Ahrens CH.

BMC Microbiol. 2019 Jun 25;19(1):143. doi: 10.1186/s12866-019-1500-0.


Simian-Human Immunodeficiency Virus SHIV.CH505 Infection of Rhesus Macaques Results in Persistent Viral Replication and Induces Intestinal Immunopathology.

Bar KJ, Coronado E, Hensley-McBain T, O'Connor MA, Osborn JM, Miller C, Gott TM, Wangari S, Iwayama N, Ahrens CY, Smedley J, Moats C, Lynch RM, Haddad EK, Haigwood NL, Fuller DH, Shaw GM, Klatt NR, Manuzak JA.

J Virol. 2019 Aug 28;93(18). pii: e00372-19. doi: 10.1128/JVI.00372-19. Print 2019 Sep 15.


An Integrated Systems Approach Unveils New Aspects of Microoxia-Mediated Regulation in Bradyrhizobium diazoefficiens.

Fernández N, Cabrera JJ, Varadarajan AR, Lutz S, Ledermann R, Roschitzki B, Eberl L, Bedmar EJ, Fischer HM, Pessi G, Ahrens CH, Mesa S.

Front Microbiol. 2019 May 7;10:924. doi: 10.3389/fmicb.2019.00924. eCollection 2019.


Snf2 controls pulcherriminic acid biosynthesis and antifungal activity of the biocontrol yeast Metschnikowia pulcherrima.

Gore-Lloyd D, Sumann I, Brachmann AO, Schneeberger K, Ortiz-Merino RA, Moreno-Beltrán M, Schläfli M, Kirner P, Santos Kron A, Rueda-Mejia MP, Somerville V, Wolfe KH, Piel J, Ahrens CH, Henk D, Freimoser FM.

Mol Microbiol. 2019 Jul;112(1):317-332. doi: 10.1111/mmi.14272. Epub 2019 May 20.


Local and regional scale habitat heterogeneity contribute to genetic adaptation in a commercially important marine mollusc (Haliotis rubra) from southeastern Australia.

Miller AD, Hoffmann AA, Tan MH, Young M, Ahrens C, Cocomazzo M, Rattray A, Ierodiaconou DA, Treml E, Sherman CDH.

Mol Ecol. 2019 Jun;28(12):3053-3072. doi: 10.1111/mec.15128. Epub 2019 Jun 9.


Standing genomic variation within coding and regulatory regions contributes to the adaptive capacity to climate in a foundation tree species.

Ahrens CW, Byrne M, Rymer PD.

Mol Ecol. 2019 May;28(10):2502-2516. doi: 10.1111/mec.15092. Epub 2019 May 13.


Pushing the limits of de novo genome assembly for complex prokaryotic genomes harboring very long, near identical repeats.

Schmid M, Frei D, Patrignani A, Schlapbach R, Frey JE, Remus-Emsermann MNP, Ahrens CH.

Nucleic Acids Res. 2018 Sep 28;46(17):8953-8965. doi: 10.1093/nar/gky726.


Chemoproteomics of matrix metalloproteases in a model of cartilage degeneration suggests functional biomarkers associated with posttraumatic osteoarthritis.

Ravindra KC, Ahrens CC, Wang Y, Ramseier JY, Wishnok JS, Griffith LG, Grodzinsky AJ, Tannenbaum SR.

J Biol Chem. 2018 Jul 20;293(29):11459-11469. doi: 10.1074/jbc.M117.818542. Epub 2018 May 23.


Metabolomics and Transcriptomics Identify Multiple Downstream Targets of Paraburkholderia phymatum σ54 During Symbiosis with Phaseolus vulgaris.

Lardi M, Liu Y, Giudice G, Ahrens CH, Zamboni N, Pessi G.

Int J Mol Sci. 2018 Apr 1;19(4). pii: E1049. doi: 10.3390/ijms19041049.


Seasonal Dynamics of Glyphosate and AMPA in Lake Greifensee: Rapid Microbial Degradation in the Epilimnion During Summer.

Huntscha S, Stravs MA, Bühlmann A, Ahrens CH, Frey JE, Pomati F, Hollender J, Buerge IJ, Balmer ME, Poiger T.

Environ Sci Technol. 2018 Apr 17;52(8):4641-4649. doi: 10.1021/acs.est.8b00314. Epub 2018 Mar 27.


The search for loci under selection: trends, biases and progress.

Ahrens CW, Rymer PD, Stow A, Bragg J, Dillon S, Umbers KDL, Dudaniec RY.

Mol Ecol. 2018 Mar;27(6):1342-1356. doi: 10.1111/mec.14549. Epub 2018 Mar 30. Review.


Pseudomonas orientalis F9: A Potent Antagonist against Phytopathogens with Phytotoxic Effect in the Apple Flower.

Zengerer V, Schmid M, Bieri M, Müller DC, Remus-Emsermann MNP, Ahrens CH, Pelludat C.

Front Microbiol. 2018 Feb 9;9:145. doi: 10.3389/fmicb.2018.00145. eCollection 2018.


Comparative Genomics of Completely Sequenced Lactobacillus helveticus Genomes Provides Insights into Strain-Specific Genes and Resolves Metagenomics Data Down to the Strain Level.

Schmid M, Muri J, Melidis D, Varadarajan AR, Somerville V, Wicki A, Moser A, Bourqui M, Wenzel C, Eugster-Meier E, Frey JE, Irmler S, Ahrens CH.

Front Microbiol. 2018 Jan 30;9:63. doi: 10.3389/fmicb.2018.00063. eCollection 2018.


An integrative strategy to identify the entire protein coding potential of prokaryotic genomes by proteogenomics.

Omasits U, Varadarajan AR, Schmid M, Goetze S, Melidis D, Bourqui M, Nikolayeva O, Québatte M, Patrignani A, Dehio C, Frey JE, Robinson MD, Wollscheid B, Ahrens CH.

Genome Res. 2017 Dec;27(12):2083-2095. doi: 10.1101/gr.218255.116. Epub 2017 Nov 15.


Institutional care paths: Development, implementation, and evaluation.

Leonard MC, Bauer SR, Ahrens C, Reddy A, Katzan I.

Am J Health Syst Pharm. 2017 Sep 15;74(18):1486-1493. doi: 10.2146/ajhp170004.


Engineering cell aggregates through incorporated polymeric microparticles.

Ahrens CC, Dong Z, Li W.

Acta Biomater. 2017 Oct 15;62:64-81. doi: 10.1016/j.actbio.2017.08.003. Epub 2017 Aug 4. Review.


Label-free, high-throughput holographic screening and enumeration of tumor cells in blood.

Singh DK, Ahrens CC, Li W, Vanapalli SA.

Lab Chip. 2017 Aug 22;17(17):2920-2932. doi: 10.1039/c7lc00149e.


Biofilm Formation Potential of Heat-Resistant Escherichia coli Dairy Isolates and the Complete Genome of Multidrug-Resistant, Heat-Resistant Strain FAM21845.

Marti R, Schmid M, Kulli S, Schneeberger K, Naskova J, Knøchel S, Ahrens CH, Hummerjohann J.

Appl Environ Microbiol. 2017 Jul 17;83(15). pii: e00628-17. doi: 10.1128/AEM.00628-17. Print 2017 Aug 1.


Adaptation and acclimation both influence photosynthetic and respiratory temperature responses in Corymbia calophylla.

Aspinwall MJ, Vårhammar A, Blackman CJ, Tjoelker MG, Ahrens C, Byrne M, Tissue DT, Rymer PD.

Tree Physiol. 2017 Aug 1;37(8):1095-1112. doi: 10.1093/treephys/tpx047.


Cell Isolation and Recovery Using Hollow Glass Microspheres Coated with Nanolayered Films for Applications in Resource-Limited Settings.

Dong Z, Ahrens CC, Yu D, Ding Z, Lim H, Li W.

ACS Appl Mater Interfaces. 2017 May 10;9(18):15265-15273. doi: 10.1021/acsami.7b02197. Epub 2017 Apr 26.


On-demand dissolution of modular, synthetic extracellular matrix reveals local epithelial-stromal communication networks.

Valdez J, Cook CD, Ahrens CC, Wang AJ, Brown A, Kumar M, Stockdale L, Rothenberg D, Renggli K, Gordon E, Lauffenburger D, White F, Griffith L.

Biomaterials. 2017 Jun;130:90-103. doi: 10.1016/j.biomaterials.2017.03.030. Epub 2017 Mar 23.


[Compression of the median nerve by chronic palmar dislocation of the lunate due to carpal collapse].

Spies CK, Schäfer M, Ahrens C, Hahn P, Unglaub F.

Unfallchirurg. 2017 Aug;120(8):712-714. doi: 10.1007/s00113-017-0345-y. German.


Genomic diversity guides conservation strategies among rare terrestrial orchid species when taxonomy remains uncertain.

Ahrens CW, Supple MA, Aitken NC, Cantrill DJ, Borevitz JO, James EA.

Ann Bot. 2017 Jun 1;119(8):1267-1277. doi: 10.1093/aob/mcx022.


Complete genome sequence of Pseudomonas citronellolis P3B5, a candidate for microbial phyllo-remediation of hydrocarbon-contaminated sites.

Remus-Emsermann MNP, Schmid M, Gekenidis MT, Pelludat C, Frey JE, Ahrens CH, Drissner D.

Stand Genomic Sci. 2016 Sep 26;11:75. doi: 10.1186/s40793-016-0190-6. eCollection 2016.


Long-Chain Alkyl Cyanides: Unprecedented Volatile Compounds Released by Pseudomonas and Micromonospora Bacteria.

Montes Vidal D, von Rymon-Lipinski AL, Ravella S, Groenhagen U, Herrmann J, Zaburannyi N, Zarbin PH, Varadarajan AR, Ahrens CH, Weisskopf L, Müller R, Schulz S.

Angew Chem Int Ed Engl. 2017 Apr 3;56(15):4342-4346. doi: 10.1002/anie.201611940. Epub 2017 Mar 9.


Label-free fingerprinting of tumor cells in bulk flow using inline digital holographic microscopy.

Singh DK, Ahrens CC, Li W, Vanapalli SA.

Biomed Opt Express. 2017 Jan 4;8(2):536-554. doi: 10.1364/BOE.8.000536. eCollection 2017 Feb 1.


Evolution of Cerebral Atrophy in a Patient with Super Refractory Status Epilepticus Treated with Barbiturate Coma.

Newey CR, George P, Nattanmai P, Ahrens C, Hantus S, Sarwal A.

Case Rep Neurol Med. 2017;2017:9131579. doi: 10.1155/2017/9131579. Epub 2017 Jan 15.


Competition assays and physiological experiments of soil and phyllosphere yeasts identify Candida subhashii as a novel antagonist of filamentous fungi.

Hilber-Bodmer M, Schmid M, Ahrens CH, Freimoser FM.

BMC Microbiol. 2017 Jan 5;17(1):4. doi: 10.1186/s12866-016-0908-z.


The Safety and Effectiveness of Intravenous Lacosamide for Refractory Status Epilepticus in the Critically Ill.

Newey CR, Le NM, Ahrens C, Sahota P, Hantus S.

Neurocrit Care. 2017 Apr;26(2):273-279. doi: 10.1007/s12028-016-0322-2.


A benchtop capillary flow layer-by-layer (CF-LbL) platform for rapid assembly and screening of biodegradable nanolayered films.

Dong Z, Tang L, Ahrens CC, Ding Z, Cao V, Castleberry S, Yan J, Li W.

Lab Chip. 2016 Nov 15;16(23):4601-4611.


Short communication: Heat-resistant Escherichia coli as potential persistent reservoir of extended-spectrum β-lactamases and Shiga toxin-encoding phages in dairy.

Marti R, Muniesa M, Schmid M, Ahrens CH, Naskova J, Hummerjohann J.

J Dairy Sci. 2016 Nov;99(11):8622-8632. doi: 10.3168/jds.2016-11076. Epub 2016 Aug 24.


Antimicrobial Monotherapy versus Combination Therapy for the Treatment of Complicated Intra-Abdominal Infections.

Petite SE, Bauer SR, Bollinger JE, Ahrens CL, Harinstein LM.

Pharmacotherapy. 2016 Nov;36(11):1138-1144. doi: 10.1002/phar.1847.


Isotropic thin PTCDA films on GaN(0 0 0 1).

Ahrens C, Flege JI, Jaye C, Fischer DA, Schmidt T, Falta J.

J Phys Condens Matter. 2016 Nov 30;28(47):475003. Epub 2016 Sep 26.


[Carpus and distal radioulnar joint : Clinical and radiological examination].

Spies CK, Langer MF, Unglaub F, Mühldorfer-Fodor M, Müller LP, Ahrens C, Schlindwein SF.

Unfallchirurg. 2016 Aug;119(8):673-89. doi: 10.1007/s00113-016-0206-0. Review. German.


Metabolomic Profiling of Bradyrhizobium diazoefficiens-Induced Root Nodules Reveals Both Host Plant-Specific and Developmental Signatures.

Lardi M, Murset V, Fischer HM, Mesa S, Ahrens CH, Zamboni N, Pessi G.

Int J Mol Sci. 2016 May 27;17(6). pii: E815. doi: 10.3390/ijms17060815.


[Perioperative Anticoagulation in Elective Hand Surgery: A Literature Review].

Ahrens C, Unglaub F, Hohendorff B, Müller LP, Spies CK.

Handchir Mikrochir Plast Chir. 2016 Jun;48(3):127-35. doi: 10.1055/s-0042-104504. Epub 2016 May 23. Review. German.


Genome-wide transcription start site mapping of Bradyrhizobium japonicum grown free-living or in symbiosis - a rich resource to identify new transcripts, proteins and to study gene regulation.

Čuklina J, Hahn J, Imakaev M, Omasits U, Förstner KU, Ljubimov N, Goebel M, Pessi G, Fischer HM, Ahrens CH, Gelfand MS, Evguenieva-Hackenberg E.

BMC Genomics. 2016 Apr 23;17:302. doi: 10.1186/s12864-016-2602-9.


Explosive cell lysis as a mechanism for the biogenesis of bacterial membrane vesicles and biofilms.

Turnbull L, Toyofuku M, Hynen AL, Kurosawa M, Pessi G, Petty NK, Osvath SR, Cárcamo-Oyarce G, Gloag ES, Shimoni R, Omasits U, Ito S, Yap X, Monahan LG, Cavaliere R, Ahrens CH, Charles IG, Nomura N, Eberl L, Whitchurch CB.

Nat Commun. 2016 Apr 14;7:11220. doi: 10.1038/ncomms11220.


Regional Genetic Structure and Environmental Variables Influence our Conservation Approach for Feather Heads (Ptilotus macrocephalus).

Ahrens CW, James EA.

J Hered. 2016 May;107(3):238-47. doi: 10.1093/jhered/esw009. Epub 2016 Feb 10.


[Fractures of the proximal interphalangeal joint: Diagnostic and operative therapy options].

Unglaub F, Langer MF, Hahn P, Müller LP, Ahrens C, Spies CK.

Unfallchirurg. 2016 Feb;119(2):133-43; quiz 144-5. doi: 10.1007/s00113-016-0142-z. Review. German.


Therapeutic drug monitoring of cerebrospinal fluid vancomycin concentration during intraventricular administration.

Popa D, Loewenstein L, Lam SW, Neuner EA, Ahrens CL, Bhimraj A.

J Hosp Infect. 2016 Feb;92(2):199-202. doi: 10.1016/j.jhin.2015.10.017. Epub 2015 Nov 6.


Volatile Organic Compounds from Native Potato-associated Pseudomonas as Potential Anti-oomycete Agents.

De Vrieze M, Pandey P, Bucheli TD, Varadarajan AR, Ahrens CH, Weisskopf L, Bailly A.

Front Microbiol. 2015 Nov 23;6:1295. doi: 10.3389/fmicb.2015.01295. eCollection 2015.


A Peptidomimetic Antibiotic Targets Outer Membrane Proteins and Disrupts Selectively the Outer Membrane in Escherichia coli.

Urfer M, Bogdanovic J, Lo Monte F, Moehle K, Zerbe K, Omasits U, Ahrens CH, Pessi G, Eberl L, Robinson JA.

J Biol Chem. 2016 Jan 22;291(4):1921-32. doi: 10.1074/jbc.M115.691725. Epub 2015 Dec 1.


The Role of FEIBA in Reversing Novel Oral Anticoagulants in Intracerebral Hemorrhage.

Dibu JR, Weimer JM, Ahrens C, Manno E, Frontera JA.

Neurocrit Care. 2016 Jun;24(3):413-9. doi: 10.1007/s12028-015-0213-y.


Uncharged Helical Modular Polypeptide Hydrogels for Cellular Scaffolds.

Ahrens CC, Welch ME, Griffith LG, Hammond PT.

Biomacromolecules. 2015 Dec 14;16(12):3774-83. doi: 10.1021/acs.biomac.5b01076. Epub 2015 Nov 9.


Mercury (II) reduction and co-precipitation of metallic mercury on hydrous ferric oxide in contaminated groundwater.

Richard JH, Bischoff C, Ahrens CGM, Biester H.

Sci Total Environ. 2016 Jan 1;539:36-44. doi: 10.1016/j.scitotenv.2015.08.116. Epub 2015 Sep 6.


Covalent Modification of Synthetic Hydrogels with Bioactive Proteins via Sortase-Mediated Ligation.

Cambria E, Renggli K, Ahrens CC, Cook CD, Kroll C, Krueger AT, Imperiali B, Griffith LG.

Biomacromolecules. 2015 Aug 10;16(8):2316-26. doi: 10.1021/acs.biomac.5b00549. Epub 2015 Jul 10.


Prehospital reversal of warfarin-related coagulopathy in intracerebral hemorrhage in a mobile stroke treatment unit.

Gomes JA, Ahrens CL, Hussain MS, Winners S, Rasmussen PA, Uchino K; Cleveland Pre-Hospital Acute Stroke Treatment Study Group.

Stroke. 2015 May;46(5):e118-20. doi: 10.1161/STROKEAHA.115.008483. Epub 2015 Apr 14. No abstract available.


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