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Items: 16


Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice.

Lindén D, Ahnmark A, Pingitore P, Ciociola E, Ahlstedt I, Andréasson AC, Sasidharan K, Madeyski-Bengtson K, Zurek M, Mancina RM, Lindblom A, Bjursell M, Böttcher G, Ståhlman M, Bohlooly-Y M, Haynes WG, Carlsson B, Graham M, Lee R, Murray S, Valenti L, Bhanot S, Åkerblad P, Romeo S.

Mol Metab. 2019 Apr;22:49-61. doi: 10.1016/j.molmet.2019.01.013. Epub 2019 Feb 5.


Targeted delivery of antisense oligonucleotides to pancreatic β-cells.

Ämmälä C, Drury WJ 3rd, Knerr L, Ahlstedt I, Stillemark-Billton P, Wennberg-Huldt C, Andersson EM, Valeur E, Jansson-Löfmark R, Janzén D, Sundström L, Meuller J, Claesson J, Andersson P, Johansson C, Lee RG, Prakash TP, Seth PP, Monia BP, Andersson S.

Sci Adv. 2018 Oct 17;4(10):eaat3386. doi: 10.1126/sciadv.aat3386. eCollection 2018 Oct.


Modeling human pancreatic beta cell dedifferentiation.

Diedisheim M, Oshima M, Albagli O, Huldt CW, Ahlstedt I, Clausen M, Menon S, Aivazidis A, Andreasson AC, Haynes WG, Marchetti P, Marselli L, Armanet M, Chimienti F, Scharfmann R.

Mol Metab. 2018 Apr;10:74-86. doi: 10.1016/j.molmet.2018.02.002. Epub 2018 Feb 8.


Dapagliflozin stimulates glucagon secretion at high glucose: experiments and mathematical simulations of human A-cells.

Pedersen MG, Ahlstedt I, El Hachmane MF, Göpel SO.

Sci Rep. 2016 Aug 18;6:31214. doi: 10.1038/srep31214.


Monoclonal antibody targeting of fibroblast growth factor receptor 1c ameliorates obesity and glucose intolerance via central mechanisms.

Lelliott CJ, Ahnmark A, Admyre T, Ahlstedt I, Irving L, Keyes F, Patterson L, Mumphrey MB, Bjursell M, Gorman T, Bohlooly-Y M, Buchanan A, Harrison P, Vaughan T, Berthoud HR, Lindén D.

PLoS One. 2014 Nov 26;9(11):e112109. doi: 10.1371/journal.pone.0112109. eCollection 2014.


Characterization of species-related differences in the pharmacology of tachykinin NK receptors 1, 2 and 3.

Leffler A, Ahlstedt I, Engberg S, Svensson A, Billger M, Oberg L, Bjursell MK, Lindström E, von Mentzer B.

Biochem Pharmacol. 2009 May 1;77(9):1522-30. doi: 10.1016/j.bcp.2009.01.020. Epub 2009 Feb 6.


Occurrence and pharmacological characterization of four human tachykinin NK2 receptor variants.

Ahlstedt I, Engberg S, Smith J, Perrey C, Moody A, Morten J, Lagerström-Fermér M, Drmota T, von Mentzer B, Påhlman I, Lindström E.

Biochem Pharmacol. 2008 Aug 15;76(4):476-81. doi: 10.1016/j.bcp.2008.06.003. Epub 2008 Jun 13.


Senktide-induced gerbil foot tapping behaviour is blocked by selective tachykinin NK1 and NK3 receptor antagonists.

Sundqvist M, Kristensson E, Adolfsson R, Leffler A, Ahlstedt I, Engberg S, Drmota T, Sigfridsson K, Jussila R, de Verdier J, Novén A, Johansson A, Påhlman I, von Mentzer B, Lindström E.

Eur J Pharmacol. 2007 Dec 22;577(1-3):78-86. Epub 2007 Sep 11.


Neurokinin 1 receptor antagonists: correlation between in vitro receptor interaction and in vivo efficacy.

Lindström E, von Mentzer B, Påhlman I, Ahlstedt I, Uvebrant A, Kristensson E, Martinsson R, Novén A, de Verdier J, Vauquelin G.

J Pharmacol Exp Ther. 2007 Sep;322(3):1286-93. Epub 2007 Jun 15.


Functional CRF receptors in BON cells stimulate serotonin release.

von Mentzer B, Murata Y, Ahlstedt I, Lindström E, Martínez V.

Biochem Pharmacol. 2007 Mar 15;73(6):805-13. Epub 2006 Nov 30.


Molecular cloning, mutations and effects of NK1 receptor antagonists reveal the human-like pharmacology of gerbil NK1 receptors.

Engberg S, Ahlstedt I, Leffler A, Lindström E, Kristensson E, Svensson A, Påhlman I, Johansson A, Drmota T, von Mentzer B.

Biochem Pharmacol. 2007 Jan 15;73(2):259-69. Epub 2006 Oct 12.


Differential expression of chemokine receptors on human IgA+ and IgG+ B cells.

Johansson C, Ahlstedt I, Furubacka S, Johnsson E, Agace WW, Quiding-Järbrink M.

Clin Exp Immunol. 2005 Aug;141(2):279-87.


Homing commitment of lymphocytes activated in the human gastric and intestinal mucosa.

Quiding-Järbrink M, Ahlstedt I, Lindholm C, Johansson EL, Lönroth H.

Gut. 2001 Oct;49(4):519-25.


Human gastric B cell responses can be induced by intestinal immunisation.

Quiding-Järbrink M, Lönroth H, Ahlstedt I, Holmgren J, Svennerholm AM.

Gut. 2001 Oct;49(4):512-8.


Role of local cytokines in increased gastric expression of the secretory component in Helicobacter pylori infection.

Ahlstedt I, Lindholm C, Lönroth H, Hamlet A, Svennerholm AM, Quiding-Järbrink M.

Infect Immun. 1999 Sep;67(9):4921-5.


Antibody-secreting cells in the stomachs of symptomatic and asymptomatic Helicobacter pylori-infected subjects.

Mattsson A, Quiding-Järbrink M, Lönroth H, Hamlet A, Ahlstedt I, Svennerholm A.

Infect Immun. 1998 Jun;66(6):2705-12.

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