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Items: 12


Mass Spectrometry and Antibody-Based Characterization of Blood Vessels from Brachylophosaurus canadensis.

Cleland TP, Schroeter ER, Zamdborg L, Zheng W, Lee JE, Tran JC, Bern M, Duncan MB, Lebleu VS, Ahlf DR, Thomas PM, Kalluri R, Kelleher NL, Schweitzer MH.

J Proteome Res. 2015 Dec 4;14(12):5252-62. doi: 10.1021/acs.jproteome.5b00675. Epub 2015 Nov 23.


Correlated mass spectrometry imaging and confocal Raman microscopy for studies of three-dimensional cell culture sections.

Ahlf DR, Masyuko RN, Hummon AB, Bohn PW.

Analyst. 2014 Sep 21;139(18):4578-85. doi: 10.1039/c4an00826j.


Large-scale top-down proteomics of the human proteome: membrane proteins, mitochondria, and senescence.

Catherman AD, Durbin KR, Ahlf DR, Early BP, Fellers RT, Tran JC, Thomas PM, Kelleher NL.

Mol Cell Proteomics. 2013 Dec;12(12):3465-73. doi: 10.1074/mcp.M113.030114. Epub 2013 Sep 10.


Developing top down proteomics to maximize proteome and sequence coverage from cells and tissues.

Ahlf DR, Thomas PM, Kelleher NL.

Curr Opin Chem Biol. 2013 Oct;17(5):787-94. doi: 10.1016/j.cbpa.2013.07.028. Epub 2013 Aug 27. Review.


Evaluation of the compact high-field orbitrap for top-down proteomics of human cells.

Ahlf DR, Compton PD, Tran JC, Early BP, Thomas PM, Kelleher NL.

J Proteome Res. 2012 Aug 3;11(8):4308-14. doi: 10.1021/pr3004216. Epub 2012 Jul 13.


A protease for 'middle-down' proteomics.

Wu C, Tran JC, Zamdborg L, Durbin KR, Li M, Ahlf DR, Early BP, Thomas PM, Sweedler JV, Kelleher NL.

Nat Methods. 2012 Jun 17;9(8):822-4. doi: 10.1038/nmeth.2074.


Nano-LC FTICR tandem mass spectrometry for top-down proteomics: routine baseline unit mass resolution of whole cell lysate proteins up to 72 kDa.

Tipton JD, Tran JC, Catherman AD, Ahlf DR, Durbin KR, Lee JE, Kellie JF, Kelleher NL, Hendrickson CL, Marshall AG.

Anal Chem. 2012 Mar 6;84(5):2111-7. doi: 10.1021/ac202651v. Epub 2012 Feb 22.


Mapping intact protein isoforms in discovery mode using top-down proteomics.

Tran JC, Zamdborg L, Ahlf DR, Lee JE, Catherman AD, Durbin KR, Tipton JD, Vellaichamy A, Kellie JF, Li M, Wu C, Sweet SM, Early BP, Siuti N, LeDuc RD, Compton PD, Thomas PM, Kelleher NL.

Nature. 2011 Oct 30;480(7376):254-8. doi: 10.1038/nature10575.


Analysis of intact protein isoforms by mass spectrometry.

Tipton JD, Tran JC, Catherman AD, Ahlf DR, Durbin KR, Kelleher NL.

J Biol Chem. 2011 Jul 22;286(29):25451-8. doi: 10.1074/jbc.R111.239442. Epub 2011 Jun 1. Review.


The emerging process of Top Down mass spectrometry for protein analysis: biomarkers, protein-therapeutics, and achieving high throughput.

Kellie JF, Tran JC, Lee JE, Ahlf DR, Thomas HM, Ntai I, Catherman AD, Durbin KR, Zamdborg L, Vellaichamy A, Thomas PM, Kelleher NL.

Mol Biosyst. 2010 Sep;6(9):1532-9. doi: 10.1039/c000896f. Epub 2010 Mar 29.


Size-sorting combined with improved nanocapillary liquid chromatography-mass spectrometry for identification of intact proteins up to 80 kDa.

Vellaichamy A, Tran JC, Catherman AD, Lee JE, Kellie JF, Sweet SM, Zamdborg L, Thomas PM, Ahlf DR, Durbin KR, Valaskovic GA, Kelleher NL.

Anal Chem. 2010 Feb 15;82(4):1234-44. doi: 10.1021/ac9021083.


A robust two-dimensional separation for top-down tandem mass spectrometry of the low-mass proteome.

Lee JE, Kellie JF, Tran JC, Tipton JD, Catherman AD, Thomas HM, Ahlf DR, Durbin KR, Vellaichamy A, Ntai I, Marshall AG, Kelleher NL.

J Am Soc Mass Spectrom. 2009 Dec;20(12):2183-91. doi: 10.1016/j.jasms.2009.08.001. Epub 2009 Aug 12.

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