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Items: 18


Understanding immune-microbiota interactions in the intestine.

Ahern PP, Maloy KJ.

Immunology. 2020 Jan;159(1):4-14. doi: 10.1111/imm.13150. Epub 2019 Nov 27. Review.


Mechanisms by which sialylated milk oligosaccharides impact bone biology in a gnotobiotic mouse model of infant undernutrition.

Cowardin CA, Ahern PP, Kung VL, Hibberd MC, Cheng J, Guruge JL, Sundaresan V, Head RD, Barile D, Mills DA, Barratt MJ, Huq S, Ahmed T, Gordon JI.

Proc Natl Acad Sci U S A. 2019 Jun 11;116(24):11988-11996. doi: 10.1073/pnas.1821770116. Epub 2019 May 28.


Lactobacillus reuteri induces gut intraepithelial CD4+CD8αα+ T cells.

Cervantes-Barragan L, Chai JN, Tianero MD, Di Luccia B, Ahern PP, Merriman J, Cortez VS, Caparon MG, Donia MS, Gilfillan S, Cella M, Gordon JI, Hsieh CS, Colonna M.

Science. 2017 Aug 25;357(6353):806-810. doi: 10.1126/science.aah5825. Epub 2017 Aug 3.


Prior Dietary Practices and Connections to a Human Gut Microbial Metacommunity Alter Responses to Diet Interventions.

Griffin NW, Ahern PP, Cheng J, Heath AC, Ilkayeva O, Newgard CB, Fontana L, Gordon JI.

Cell Host Microbe. 2017 Jan 11;21(1):84-96. doi: 10.1016/j.chom.2016.12.006. Epub 2016 Dec 29.


Impact of the gut microbiota on enhancer accessibility in gut intraepithelial lymphocytes.

Semenkovich NP, Planer JD, Ahern PP, Griffin NW, Lin CY, Gordon JI.

Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):14805-14810. doi: 10.1073/pnas.1617793113. Epub 2016 Dec 1.


Effects of a gut pathobiont in a gnotobiotic mouse model of childhood undernutrition.

Wagner VE, Dey N, Guruge J, Hsiao A, Ahern PP, Semenkovich NP, Blanton LV, Cheng J, Griffin N, Stappenbeck TS, Ilkayeva O, Newgard CB, Petri W, Haque R, Ahmed T, Gordon JI.

Sci Transl Med. 2016 Nov 23;8(366):366ra164.


T-bet is a key modulator of IL-23-driven pathogenic CD4(+) T cell responses in the intestine.

Krausgruber T, Schiering C, Adelmann K, Harrison OJ, Chomka A, Pearson C, Ahern PP, Shale M, Oukka M, Powrie F.

Nat Commun. 2016 May 19;7:11627. doi: 10.1038/ncomms11627.


Analysis of gene-environment interactions in postnatal development of the mammalian intestine.

Rakoff-Nahoum S, Kong Y, Kleinstein SH, Subramanian S, Ahern PP, Gordon JI, Medzhitov R.

Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):1929-36. doi: 10.1073/pnas.1424886112.


An evolving perspective about the origins of childhood undernutrition and nutritional interventions that includes the gut microbiome.

Ahmed T, Auble D, Berkley JA, Black R, Ahern PP, Hossain M, Hsieh A, Ireen S, Arabi M, Gordon JI.

Ann N Y Acad Sci. 2014 Dec;1332:22-38. doi: 10.1111/nyas.12487. Epub 2014 Aug 12. Review.


Mining the human gut microbiota for effector strains that shape the immune system.

Ahern PP, Faith JJ, Gordon JI.

Immunity. 2014 Jun 19;40(6):815-23. doi: 10.1016/j.immuni.2014.05.012.


Identifying gut microbe-host phenotype relationships using combinatorial communities in gnotobiotic mice.

Faith JJ, Ahern PP, Ridaura VK, Cheng J, Gordon JI.

Sci Transl Med. 2014 Jan 22;6(220):220ra11. doi: 10.1126/scitranslmed.3008051.


Metabolic niche of a prominent sulfate-reducing human gut bacterium.

Rey FE, Gonzalez MD, Cheng J, Wu M, Ahern PP, Gordon JI.

Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13582-7. doi: 10.1073/pnas.1312524110. Epub 2013 Jul 29.


The absence of a microbiota enhances TSLP expression in mice with defective skin barrier but does not affect the severity of their allergic inflammation.

Yockey LJ, Demehri S, Turkoz M, Turkoz A, Ahern PP, Jassim O, Manivasagam S, Kearney JF, Gordon JI, Kopan R.

J Invest Dermatol. 2013 Dec;133(12):2714-2721. doi: 10.1038/jid.2013.228. Epub 2013 May 22.


Human nutrition, the gut microbiome and the immune system.

Kau AL, Ahern PP, Griffin NW, Goodman AL, Gordon JI.

Nature. 2011 Jun 15;474(7351):327-36. doi: 10.1038/nature10213. Review.


Interleukin-23 drives intestinal inflammation through direct activity on T cells.

Ahern PP, Schiering C, Buonocore S, McGeachy MJ, Cua DJ, Maloy KJ, Powrie F.

Immunity. 2010 Aug 27;33(2):279-88. doi: 10.1016/j.immuni.2010.08.010. Erratum in: Immunity. 2011 Mar 25;34(3):448.


Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology.

Buonocore S, Ahern PP, Uhlig HH, Ivanov II, Littman DR, Maloy KJ, Powrie F.

Nature. 2010 Apr 29;464(7293):1371-5. doi: 10.1038/nature08949.


The interleukin-23 axis in intestinal inflammation.

Ahern PP, Izcue A, Maloy KJ, Powrie F.

Immunol Rev. 2008 Dec;226:147-59. doi: 10.1111/j.1600-065X.2008.00705.x. Review.


Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis.

Izcue A, Hue S, Buonocore S, Arancibia-Cárcamo CV, Ahern PP, Iwakura Y, Maloy KJ, Powrie F.

Immunity. 2008 Apr;28(4):559-70. doi: 10.1016/j.immuni.2008.02.019.

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