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Items: 1 to 50 of 65

1.

Distribution and infection-related functions of bacillithiol in Staphylococcus aureus.

Pöther DC, Gierok P, Harms M, Mostertz J, Hochgräfe F, Antelmann H, Hamilton CJ, Borovok I, Lalk M, Aharonowitz Y, Hecker M.

Int J Med Microbiol. 2013 Apr;303(3):114-23. doi: 10.1016/j.ijmm.2013.01.003. Epub 2013 Mar 6.

PMID:
23517692
2.

Universal stress proteins are important for oxidative and acid stress resistance and growth of Listeria monocytogenes EGD-e in vitro and in vivo.

Seifart Gomes C, Izar B, Pazan F, Mohamed W, Mraheil MA, Mukherjee K, Billion A, Aharonowitz Y, Chakraborty T, Hain T.

PLoS One. 2011;6(9):e24965. doi: 10.1371/journal.pone.0024965. Epub 2011 Sep 30.

3.

Implications of the inability of Listeria monocytogenes EGD-e to grow anaerobically due to a deletion in the class III NrdD ribonucleotide reductase for its use as a model laboratory strain.

Ofer A, Kreft J, Logan DT, Cohen G, Borovok I, Aharonowitz Y.

J Bacteriol. 2011 Jun;193(12):2931-40. doi: 10.1128/JB.01405-10. Epub 2011 Apr 8.

4.

Staphylococcus aureus NrdH redoxin is a reductant of the class Ib ribonucleotide reductase.

Rabinovitch I, Yanku M, Yeheskel A, Cohen G, Borovok I, Aharonowitz Y.

J Bacteriol. 2010 Oct;192(19):4963-72. doi: 10.1128/JB.00539-10. Epub 2010 Jul 30.

5.

Diamide triggers mainly S Thiolations in the cytoplasmic proteomes of Bacillus subtilis and Staphylococcus aureus.

Pöther DC, Liebeke M, Hochgräfe F, Antelmann H, Becher D, Lalk M, Lindequist U, Borovok I, Cohen G, Aharonowitz Y, Hecker M.

J Bacteriol. 2009 Dec;191(24):7520-30. doi: 10.1128/JB.00937-09. Epub 2009 Oct 16.

6.

Identification and characterization of gshA, a gene encoding the glutamate-cysteine ligase in the halophilic archaeon Haloferax volcanii.

Malki L, Yanku M, Borovok I, Cohen G, Mevarech M, Aharonowitz Y.

J Bacteriol. 2009 Aug;191(16):5196-204. doi: 10.1128/JB.00297-09. Epub 2009 Jun 12.

7.

Functional analysis of the Streptomyces coelicolor NrdR ATP-cone domain: role in nucleotide binding, oligomerization, and DNA interactions.

Grinberg I, Shteinberg T, Hassan AQ, Aharonowitz Y, Borovok I, Cohen G.

J Bacteriol. 2009 Feb;191(4):1169-79. doi: 10.1128/JB.01145-08. Epub 2008 Dec 1.

8.

Pathogenomics: an updated European Research Agenda.

Demuth A, Aharonowitz Y, Bachmann TT, Blum-Oehler G, Buchrieser C, Covacci A, Dobrindt U, Emödy L, van der Ende A, Ewbank J, Fernández LA, Frosch M, García-Del Portillo F, Gilmore MS, Glaser P, Goebel W, Hasnain SE, Heesemann J, Islam K, Korhonen T, Maiden M, Meyer TF, Montecucco C, Oswald E, Parkhill J, Pucciarelli MG, Ron E, Svanborg C, Uhlin BE, Wai SN, Wehland J, Hacker J.

Infect Genet Evol. 2008 May;8(3):386-93. doi: 10.1016/j.meegid.2008.01.005. Epub 2008 Jan 18. Review.

PMID:
18321793
9.

Staphylococcus aureus ArcR controls expression of the arginine deiminase operon.

Makhlin J, Kofman T, Borovok I, Kohler C, Engelmann S, Cohen G, Aharonowitz Y.

J Bacteriol. 2007 Aug;189(16):5976-86. Epub 2007 Jun 8.

10.

NrdR controls differential expression of the Escherichia coli ribonucleotide reductase genes.

Torrents E, Grinberg I, Gorovitz-Harris B, Lundström H, Borovok I, Aharonowitz Y, Sjöberg BM, Cohen G.

J Bacteriol. 2007 Jul;189(14):5012-21. Epub 2007 May 11.

11.

The Streptomyces NrdR transcriptional regulator is a Zn ribbon/ATP cone protein that binds to the promoter regions of class Ia and class II ribonucleotide reductase operons.

Grinberg I, Shteinberg T, Gorovitz B, Aharonowitz Y, Cohen G, Borovok I.

J Bacteriol. 2006 Nov;188(21):7635-44. Epub 2006 Sep 1.

12.

A sequence-based filtering method for ncRNA identification and its application to searching for riboswitch elements.

Zhang S, Borovok I, Aharonowitz Y, Sharan R, Bafna V.

Bioinformatics. 2006 Jul 15;22(14):e557-65.

PMID:
16873520
13.

Coenzyme B12 controls transcription of the Streptomyces class Ia ribonucleotide reductase nrdABS operon via a riboswitch mechanism.

Borovok I, Gorovitz B, Schreiber R, Aharonowitz Y, Cohen G.

J Bacteriol. 2006 Apr;188(7):2512-20.

14.

A multidomain fusion protein in Listeria monocytogenes catalyzes the two primary activities for glutathione biosynthesis.

Gopal S, Borovok I, Ofer A, Yanku M, Cohen G, Goebel W, Kreft J, Aharonowitz Y.

J Bacteriol. 2005 Jun;187(11):3839-47.

15.

Alternative oxygen-dependent and oxygen-independent ribonucleotide reductases in Streptomyces: cross-regulation and physiological role in response to oxygen limitation.

Borovok I, Gorovitz B, Yanku M, Schreiber R, Gust B, Chater K, Aharonowitz Y, Cohen G.

Mol Microbiol. 2004 Nov;54(4):1022-35.

16.

Glutathione is a target in tellurite toxicity and is protected by tellurite resistance determinants in Escherichia coli.

Turner RJ, Aharonowitz Y, Weiner JH, Taylor DE.

Can J Microbiol. 2001 Jan;47(1):33-40.

PMID:
15049447
17.

Role of a cysteine synthase in Staphylococcus aureus.

Lithgow JK, Hayhurst EJ, Cohen G, Aharonowitz Y, Foster SJ.

J Bacteriol. 2004 Mar;186(6):1579-90.

18.
19.

Streptomyces spp. contain class Ia and class II ribonucleotide reductases: expression analysis of the genes in vegetative growth.

Borovok I, Kreisberg-Zakarin R, Yanko M, Schreiber R, Myslovati M, Aslund F, Holmgren A, Cohen G, Aharonowitz Y.

Microbiology. 2002 Feb;148(Pt 2):391-404.

PMID:
11832503
20.

Excretion of a phosphorus-containing carbohydrate by Streptomyces sp. A50.

Ben-Bashat D, Meller Y, Aharonowitz Y, Gutnick D, Carmeli S, Navon G.

J Nat Prod. 2001 Dec;64(12):1538-40.

PMID:
11754606
21.

Defining the disulphide stress response in Streptomyces coelicolor A3(2): identification of the sigmaR regulon.

Paget MS, Molle V, Cohen G, Aharonowitz Y, Buttner MJ.

Mol Microbiol. 2001 Nov;42(4):1007-20.

22.
23.

Structure-function studies of the non-heme iron active site of isopenicillin N synthase: some implications for catalysis.

Kreisberg-Zakarin R, Borovok I, Yanko M, Frolow F, Aharonowitz Y, Cohen G.

Biophys Chem. 2000 Aug 30;86(2-3):109-18.

PMID:
11026676
24.

Recent advances in the structure and function of isopenicillin N synthase.

Kreisberg-Zakarin R, Borovok I, Yanko M, Aharonowitz Y, Cohen G.

Antonie Van Leeuwenhoek. 1999 Jan-Feb;75(1-2):33-9. Review.

PMID:
10422580
25.

Gene organization in the trxA/B-oriC region of the Streptomyces coelicolor chromosome and comparison with other eubacteria.

Gal-Mor O, Borovok I, Av-Gay Y, Cohen G, Aharonowitz Y.

Gene. 1998 Sep 14;217(1-2):83-90.

PMID:
9795152
26.

The thioredoxin reductase system of mycoplasmas.

Ben-Menachem G, Himmelreich R, Herrmann R, Aharonowitz Y, Rottem S.

Microbiology. 1997 Jun;143 ( Pt 6):1933-40.

PMID:
9202470
27.
28.

Distribution of thiols in microorganisms: mycothiol is a major thiol in most actinomycetes.

Newton GL, Arnold K, Price MS, Sherrill C, Delcardayre SB, Aharonowitz Y, Cohen G, Davies J, Fahey RC, Davis C.

J Bacteriol. 1996 Apr;178(7):1990-5.

29.

Ferrous active site of isopenicillin N synthase: genetic and sequence analysis of the endogenous ligands.

Borovok I, Landman O, Kreisberg-Zakarin R, Aharonowitz Y, Cohen G.

Biochemistry. 1996 Feb 13;35(6):1981-7.

PMID:
8639682
30.

The structure of U17 isolated from Streptomyces clavuligerus and its properties as an antioxidant thiol.

Newton GL, Bewley CA, Dwyer TJ, Horn R, Aharonowitz Y, Cohen G, Davies J, Faulkner DJ, Fahey RC.

Eur J Biochem. 1995 Jun 1;230(2):821-5.

31.

The thioredoxin system of Penicillium chrysogenum and its possible role in penicillin biosynthesis.

Cohen G, Argaman A, Schreiber R, Mislovati M, Aharonowitz Y.

J Bacteriol. 1994 Feb;176(4):973-84.

32.

Thioredoxin-thioredoxin reductase system of Streptomyces clavuligerus: sequences, expression, and organization of the genes.

Cohen G, Yanko M, Mislovati M, Argaman A, Schreiber R, Av-Gay Y, Aharonowitz Y.

J Bacteriol. 1993 Aug;175(16):5159-67.

33.

Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase, the multienzyme integrating the four primary reactions in beta-lactam biosynthesis, as a model peptide synthetase.

Aharonowitz Y, Bergmeyer J, Cantoral JM, Cohen G, Demain AL, Fink U, Kinghorn J, Kleinkauf H, MacCabe A, Palissa H, et al.

Biotechnology (N Y). 1993 Jul;11(7):807-10. Review.

PMID:
7763859
34.

Low-molecular-weight thiols in streptomycetes and their potential role as antioxidants.

Newton GL, Fahey RC, Cohen G, Aharonowitz Y.

J Bacteriol. 1993 May;175(9):2734-42.

36.

Streptomyces contain a 7.0 kDa cold shock like protein.

Av-Gay Y, Aharonowitz Y, Cohen G.

Nucleic Acids Res. 1992 Oct 25;20(20):5478. No abstract available.

37.

Enzymatic characterisation of the multifunctional enzyme delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase from Streptomyces clavuligerus.

Schwecke T, Aharonowitz Y, Palissa H, von Döhren H, Kleinkauf H, van Liempt H.

Eur J Biochem. 1992 Apr 15;205(2):687-94.

38.

Penicillin and cephalosporin biosynthetic genes: structure, organization, regulation, and evolution.

Aharonowitz Y, Cohen G, Martin JF.

Annu Rev Microbiol. 1992;46:461-95. Review.

PMID:
1444264
39.
40.

Evolution of isopenicillin N synthase genes may have involved horizontal gene transfer.

Landan G, Cohen G, Aharonowitz Y, Shuali Y, Graur D, Shiffman D.

Mol Biol Evol. 1990 Sep;7(5):399-406. Review.

PMID:
2263192
41.

Microbial isopenicillin N synthase genes: structure, function, diversity and evolution.

Cohen G, Shiffman D, Mevarech M, Aharonowitz Y.

Trends Biotechnol. 1990 Apr;8(4):105-11. Review.

PMID:
1366527
42.

Nucleotide sequence of the isopenicillin N synthase gene (pcbC) of the gram negative Flavobacterium sp. SC 12,154.

Shiffman D, Cohen G, Aharonowitz Y, Palissa H, von Dohren H, Kleinkauf H, Mevarech M.

Nucleic Acids Res. 1990 Feb 11;18(3):660. No abstract available.

43.

Cloning and comparative sequence analysis of the gene coding for isopenicillin N synthase in Streptomyces.

Shiffman D, Mevarech M, Jensen SE, Cohen G, Aharonowitz Y.

Mol Gen Genet. 1988 Nov;214(3):562-9.

PMID:
3216857
44.

Isolation and characterization of a linear DNA plasmid from Streptomyces clavuligerus.

Keen CL, Mendelovitz S, Cohen G, Aharonowitz Y, Roy KL.

Mol Gen Genet. 1988 Apr;212(1):172-6.

PMID:
2836705
45.

Cloning and nucleotide sequence determination of the isopenicillin N synthetase gene from Streptomyces clavuligerus.

Leskiw BK, Aharonowitz Y, Mevarech M, Wolfe S, Vining LC, Westlake DW, Jensen SE.

Gene. 1988;62(2):187-96.

PMID:
3130293
46.

Purification of isopenicillin N synthetase from Streptomyces clavuligerus.

Jensen SE, Leskiw BK, Vining LC, Aharonowitz Y, Westlake DW, Wolfe S.

Can J Microbiol. 1986 Dec;32(12):953-8.

PMID:
3815161
47.

Synthesis of 19-hydroxyaldosterone and the 3 beta-hydroxy-5-ene analog of aldosterone, active mineralocorticoids.

Harnik M, Kashman Y, Aharonowitz Y, Morris DJ.

J Steroid Biochem. 1985 Aug;23(2):207-18.

PMID:
4033120
48.

Regulatory mutants of Streptomyces clavuligerus affected in free diaminopimelic acid content and antibiotic biosynthesis.

Aharonowitz Y, Mendelovitz S, Kirenberg F, Kuper V.

J Bacteriol. 1984 Jan;157(1):337-40.

49.

1-Ene-steroid reductase of Mycobacterium sp. NRRL B-3805.

Goren T, Harnik M, Rimon S, Aharonowitz Y.

J Steroid Biochem. 1983 Dec;19(6):1789-97.

PMID:
6584690
50.

Tetra- and hexahydro derivatives of aldosterone and 18-hydroxycorticosterone by chemical and microbial reductions.

Harnik M, Aharonowitz Y, Lamed R, Kashman Y.

J Steroid Biochem. 1983 Oct;19(4):1441-50.

PMID:
6645485

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