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Items: 40


An activatable PET imaging radioprobe is a dynamic reporter of myeloperoxidase activity in vivo.

Wang C, Keliher E, Zeller MWG, Wojtkiewicz GR, Aguirre AD, Buckbinder L, Kim HY, Chen J, Maresca K, Ahmed MS, Motlagh NJ, Nahrendorf M, Chen JW.

Proc Natl Acad Sci U S A. 2019 Jun 11;116(24):11966-11971. doi: 10.1073/pnas.1818434116. Epub 2019 May 23.


A Supramolecular Nanocarrier for Delivery of Amiodarone Anti-Arrhythmic Therapy to the Heart.

Ahmed MS, Rodell CB, Hulsmans M, Kohler RH, Aguirre AD, Nahrendorf M, Weissleder R.

Bioconjug Chem. 2019 Mar 20;30(3):733-740. doi: 10.1021/acs.bioconjchem.8b00882. Epub 2019 Jan 18.


A Miniaturized, Programmable Pacemaker for Long-Term Studies in the Mouse.

Hulsmans M, Aguirre AD, Bonner MD, Bapat A, Cremer S, Iwamoto Y, King KR, Swirski FK, Milan DJ, Weissleder R, Nahrendorf M.

Circ Res. 2018 Nov 9;123(11):1208-1219. doi: 10.1161/CIRCRESAHA.118.313429.


Special Section Guest Editorial: Translational Biophotonics.

Aguirre AD, Apiou-Sbirlea G, Roblyer D, Tromberg BJ.

J Biomed Opt. 2017 Dec;22(12):1-2. doi: 10.1117/1.JBO.22.12.121601.


IRF3 and type I interferons fuel a fatal response to myocardial infarction.

King KR, Aguirre AD, Ye YX, Sun Y, Roh JD, Ng RP Jr, Kohler RH, Arlauckas SP, Iwamoto Y, Savol A, Sadreyev RI, Kelly M, Fitzgibbons TP, Fitzgerald KA, Mitchison T, Libby P, Nahrendorf M, Weissleder R.

Nat Med. 2017 Dec;23(12):1481-1487. doi: 10.1038/nm.4428. Epub 2017 Nov 6.


Clinical Predictors for Lack of Favorable Vascular Response to Statin Therapy in Patients With Coronary Artery Disease: A Serial Optical Coherence Tomography Study.

Minami Y, Wang Z, Aguirre AD, Ong DS, Kim CJ, Uemura S, Soeda T, Lee H, Fujimoto J, Jang IK.

J Am Heart Assoc. 2017 Nov 1;6(11). pii: e006241. doi: 10.1161/JAHA.117.006241.


Dynamic neointimal pattern after drug-eluting stent implantation defined by optical coherence tomography.

Yamamoto E, Xing L, Higuma T, Minami Y, Bryniarski K, Zanchin T, Wang Z, Aguirre AD, Lee H, Jang IK.

Coron Artery Dis. 2017 Nov;28(7):557-563. doi: 10.1097/MCA.0000000000000534.


Clinical Significance of Lipid-Rich Plaque Detected by Optical Coherence Tomography: A 4-Year Follow-Up Study.

Xing L, Higuma T, Wang Z, Aguirre AD, Mizuno K, Takano M, Dauerman HL, Park SJ, Jang Y, Kim CJ, Kim SJ, Choi SY, Itoh T, Uemura S, Lowe H, Walters DL, Barlis P, Lee S, Lerman A, Toma C, Tan JWC, Yamamoto E, Bryniarski K, Dai J, Zanchin T, Zhang S, Yu B, Lee H, Fujimoto J, Fuster V, Jang IK.

J Am Coll Cardiol. 2017 May 23;69(20):2502-2513. doi: 10.1016/j.jacc.2017.03.556.


Macrophages Facilitate Electrical Conduction in the Heart.

Hulsmans M, Clauss S, Xiao L, Aguirre AD, King KR, Hanley A, Hucker WJ, Wülfers EM, Seemann G, Courties G, Iwamoto Y, Sun Y, Savol AJ, Sager HB, Lavine KJ, Fishbein GA, Capen DE, Da Silva N, Miquerol L, Wakimoto H, Seidman CE, Seidman JG, Sadreyev RI, Naxerova K, Mitchell RN, Brown D, Libby P, Weissleder R, Swirski FK, Kohl P, Vinegoni C, Milan DJ, Ellinor PT, Nahrendorf M.

Cell. 2017 Apr 20;169(3):510-522.e20. doi: 10.1016/j.cell.2017.03.050.


Polyglucose nanoparticles with renal elimination and macrophage avidity facilitate PET imaging in ischaemic heart disease.

Keliher EJ, Ye YX, Wojtkiewicz GR, Aguirre AD, Tricot B, Senders ML, Groenen H, Fay F, Perez-Medina C, Calcagno C, Carlucci G, Reiner T, Sun Y, Courties G, Iwamoto Y, Kim HY, Wang C, Chen JW, Swirski FK, Wey HY, Hooker J, Fayad ZA, Mulder WJ, Weissleder R, Nahrendorf M.

Nat Commun. 2017 Jan 16;8:14064. doi: 10.1038/ncomms14064.


Prevalence and Predictors of Multiple Coronary Plaque Ruptures: In Vivo 3-Vessel Optical Coherence Tomography Imaging Study.

Vergallo R, Uemura S, Soeda T, Minami Y, Cho JM, Ong DS, Aguirre AD, Gao L, Biasucci LM, Crea F, Yu B, Lee H, Kim CJ, Jang IK.

Arterioscler Thromb Vasc Biol. 2016 Nov;36(11):2229-2238. Epub 2016 Sep 15.


Quantitative analysis of the side-branch orifice after bifurcation stenting using en-face processing of OCT images: a comparison between Xience V and Resolute Integrity stents.

Minami Y, Wang Z, Aguirre AD, Lee S, Uemura S, Soeda T, Vergallo R, Raffel OC, Barlis P, Itoh T, Lee H, Fujimoto J, Jang IK.

Coron Artery Dis. 2016 Jan;27(1):19-28. doi: 10.1097/MCA.0000000000000319.


Imaging the beating heart in the mouse using intravital microscopy techniques.

Vinegoni C, Aguirre AD, Lee S, Weissleder R.

Nat Protoc. 2015 Nov;10(11):1802-19. doi: 10.1038/nprot.2015.119. Epub 2015 Oct 22.


Recurrent myocardial infarctions and premature coronary atherosclerosis in a 23-year-old man with antiphospholipid syndrome.

Vergallo R, Aguirre AD, Abtahian F, Minami Y, Soeda T, Chatzizisis YS, Croce K, Jang IK.

Thromb Haemost. 2016 Jan;115(2):237-9. doi: 10.1160/TH15-05-0412. Epub 2015 Oct 1. No abstract available.


New techniques for motion-artifact-free in vivo cardiac microscopy.

Vinegoni C, Lee S, Aguirre AD, Weissleder R.

Front Physiol. 2015 May 12;6:147. doi: 10.3389/fphys.2015.00147. eCollection 2015. Review.


Impacts of lesion angle on incidence and distribution of acute vessel wall injuries and strut malapposition after drug-eluting stent implantation assessed by optical coherence tomography.

Minami Y, Ong DS, Uemura S, Wang Z, Aguirre AD, Mukhopadhyay S, Soeda T, Vergallo R, Jia H, Tian J, Hu S, Kim SJ, Park CB, Dauerman HL, Lee S, Jang IK.

Eur Heart J Cardiovasc Imaging. 2015 Dec;16(12):1390-8. doi: 10.1093/ehjci/jev108. Epub 2015 Apr 29.


Intravital imaging of cardiac function at the single-cell level.

Aguirre AD, Vinegoni C, Sebas M, Weissleder R.

Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):11257-62. doi: 10.1073/pnas.1401316111. Epub 2014 Jul 22.


Identifying early changes in myocardial microstructure in hypertensive heart disease.

Hiremath P, Bauer M, Aguirre AD, Cheng HW, Unno K, Patel RB, Harvey BW, Chang WT, Groarke JD, Liao R, Cheng S.

PLoS One. 2014 May 15;9(5):e97424. doi: 10.1371/journal.pone.0097424. eCollection 2014.


Magnetic ligation method for quantitative detection of microRNAs.

Liong M, Im H, Majmudar MD, Aguirre AD, Sebas M, Lee H, Weissleder R.

Adv Healthc Mater. 2014 Jul;3(7):1015-9. doi: 10.1002/adhm.201300672. Epub 2014 Feb 14.


Residual thrombus pattern in patients with ST-segment elevation myocardial infarction caused by plaque erosion versus plaque rupture after successful fibrinolysis: an optical coherence tomography study.

Hu S, Yonetsu T, Jia H, Karanasos A, Aguirre AD, Tian J, Abtahian F, Vergallo R, Soeda T, Lee H, McNulty I, Kato K, Yu B, Mizuno K, Toutouzas K, Stefanadis C, Jang IK.

J Am Coll Cardiol. 2014 Apr 8;63(13):1336-1338. doi: 10.1016/j.jacc.2013.11.025. Epub 2013 Dec 18. No abstract available.


Pancoronary plaque vulnerability in patients with acute coronary syndrome and ruptured culprit plaque: a 3-vessel optical coherence tomography study.

Vergallo R, Ren X, Yonetsu T, Kato K, Uemura S, Yu B, Jia H, Abtahian F, Aguirre AD, Tian J, Hu S, Soeda T, Lee H, McNulty I, Park SJ, Jang Y, Prasad A, Lee S, Zhang S, Porto I, Biasucci LM, Crea F, Jang IK.

Am Heart J. 2014 Jan;167(1):59-67. doi: 10.1016/j.ahj.2013.10.011. Epub 2013 Oct 19.


Ultrahigh speed spectral-domain optical coherence microscopy.

Lee HC, Liu JJ, Sheikine Y, Aguirre AD, Connolly JL, Fujimoto JG.

Biomed Opt Express. 2013 Jul 1;4(8):1236-54. doi: 10.1364/BOE.4.001236. eCollection 2013.


In vivo diagnosis of plaque erosion and calcified nodule in patients with acute coronary syndrome by intravascular optical coherence tomography.

Jia H, Abtahian F, Aguirre AD, Lee S, Chia S, Lowe H, Kato K, Yonetsu T, Vergallo R, Hu S, Tian J, Lee H, Park SJ, Jang YS, Raffel OC, Mizuno K, Uemura S, Itoh T, Kakuta T, Choi SY, Dauerman HL, Prasad A, Toma C, McNulty I, Zhang S, Yu B, Fuster V, Narula J, Virmani R, Jang IK.

J Am Coll Cardiol. 2013 Nov 5;62(19):1748-58. doi: 10.1016/j.jacc.2013.05.071. Epub 2013 Jun 27.


Integrated optical coherence tomography and optical coherence microscopy imaging of ex vivo human renal tissues.

Lee HC, Zhou C, Cohen DW, Mondelblatt AE, Wang Y, Aguirre AD, Shen D, Sheikine Y, Fujimoto JG, Connolly JL.

J Urol. 2012 Feb;187(2):691-9. doi: 10.1016/j.juro.2011.09.149. Epub 2011 Dec 16.


Integrated optical coherence tomography and microscopy for ex vivo multiscale evaluation of human breast tissues.

Zhou C, Cohen DW, Wang Y, Lee HC, Mondelblatt AE, Tsai TH, Aguirre AD, Fujimoto JG, Connolly JL.

Cancer Res. 2010 Dec 15;70(24):10071-9. doi: 10.1158/0008-5472.CAN-10-2968. Epub 2010 Nov 5.


High speed optical coherence microscopy with autofocus adjustment and a miniaturized endoscopic imaging probe.

Aguirre AD, Sawinski J, Huang SW, Zhou C, Denk W, Fujimoto JG.

Opt Express. 2010 Mar 1;18(5):4222-39. doi: 10.1364/OE.18.004222.


Cellular resolution ex vivo imaging of gastrointestinal tissues with optical coherence microscopy.

Aguirre AD, Chen Y, Bryan B, Mashimo H, Huang Q, Connolly JL, Fujimoto JG.

J Biomed Opt. 2010 Jan-Feb;15(1):016025. doi: 10.1117/1.3322704.


Ex vivo imaging of human thyroid pathology using integrated optical coherence tomography and optical coherence microscopy.

Zhou C, Wang Y, Aguirre AD, Tsai TH, Cohen DW, Connolly JL, Fujimoto JG.

J Biomed Opt. 2010 Jan-Feb;15(1):016001. doi: 10.1117/1.3306696.


Optical coherence tomography (OCT) reveals depth-resolved dynamics during functional brain activation.

Chen Y, Aguirre AD, Ruvinskaya L, Devor A, Boas DA, Fujimoto JG.

J Neurosci Methods. 2009 Mar 30;178(1):162-73. doi: 10.1016/j.jneumeth.2008.11.026. Epub 2008 Dec 11.


Effects of axial resolution improvement on optical coherence tomography (OCT) imaging of gastrointestinal tissues.

Chen Y, Aguirre AD, Hsiung PL, Huang SW, Mashimo H, Schmitt JM, Fujimoto JG.

Opt Express. 2008 Feb 18;16(4):2469-85.


High-resolution line-scanning optical coherence microscopy.

Chen Y, Huang SW, Aguirre AD, Fujimoto JG.

Opt Lett. 2007 Jul 15;32(14):1971-3.


Benign and malignant lesions in the human breast depicted with ultrahigh resolution and three-dimensional optical coherence tomography.

Hsiung PL, Phatak DR, Chen Y, Aguirre AD, Fujimoto JG, Connolly JL.

Radiology. 2007 Sep;244(3):865-74. Epub 2007 Jul 13.


High-resolution three-dimensional optical coherence tomography imaging of kidney microanatomy ex vivo.

Chen Y, Andrews PM, Aguirre AD, Schmitt JM, Fujimoto JG.

J Biomed Opt. 2007 May-Jun;12(3):034008.


Ultrahigh resolution optical coherence tomography of Barrett's esophagus: preliminary descriptive clinical study correlating images with histology.

Chen Y, Aguirre AD, Hsiung PL, Desai S, Herz PR, Pedrosa M, Huang Q, Figueiredo M, Huang SW, Koski A, Schmitt JM, Fujimoto JG, Mashimo H.

Endoscopy. 2007 Jul;39(7):599-605.


Swept source optical coherence microscopy using a Fourier domain mode-locked laser.

Huang SW, Aguirre AD, Huber RA, Adler DC, Fujimoto JG.

Opt Express. 2007 May 14;15(10):6210-7.


Two-axis MEMS Scanning Catheter for Ultrahigh Resolution Three-dimensional and En Face Imaging.

Aguirre AD, Hertz PR, Chen Y, Fujimoto JG, Piyawattanametha W, Fan L, Wu MC.

Opt Express. 2007 Mar 5;15(5):2445-53.


Depth-resolved imaging of functional activation in the rat cerebral cortex using optical coherence tomography.

Aguirre AD, Chen Y, Fujimoto JG, Ruvinskaya L, Devor A, Boas DA.

Opt Lett. 2006 Dec 1;31(23):3459-61.


Ultrahigh-resolution and 3-dimensional optical coherence tomography ex vivo imaging of the large and small intestines.

Hsiung PL, Pantanowitz L, Aguirre AD, Chen Y, Phatak D, Ko TH, Bourquin S, Schnitt SJ, Raza S, Connolly JL, Mashimo H, Fujimoto JG.

Gastrointest Endosc. 2005 Oct;62(4):561-74.


Micromotor endoscope catheter for in vivo, ultrahigh-resolution optical coherence tomography.

Herz PR, Chen Y, Aguirre AD, Schneider K, Hsiung P, Fujimoto JG, Madden K, Schmitt J, Goodnow J, Petersen C.

Opt Lett. 2004 Oct 1;29(19):2261-3.


High-resolution optical coherence microscopy for high-speed, in vivo cellular imaging.

Aguirre AD, Hsiung P, Ko TH, Hartl I, Fujimoto JG.

Opt Lett. 2003 Nov 1;28(21):2064-6.


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